Abstract: Embodiments of the disclosure provide a circuit, chip, system, and method for eliminating random perturbation. The circuit includes a weight calculating module for receiving digital signals and random perturbation digital quantity, using least mean square error algorithm to calculate weight deviation iteration coefficient based on digital signal and digital quantity, and updating perturbation weight in real-time according to weight deviation iteration coefficient; and a perturbation eliminating module for eliminating perturbation signal in output digital signal of quantizer according to perturbation weight updated in real-time and updating perturbation weight in real-time according to weight deviation iteration coefficient, and then calculating current perturbation weight in real time to realize self-calibration of perturbation weight.

Abstract: The present disclosure relates to an electrode for CO2 electroreduction in an acidic electrolyte comprising cation species, the electrode comprising: a substrate, a metal-based catalyst material, and a cation-augmenting material; wherein the cation-augmenting material comprises an acidic group exchanging protons with the cation species of the acidic electrolyte so as to increase a concentration of the cation species at a surface of the electrode.

Abstract: A liquid explosive for in-situ explosive fracturing in low-permeability oilfields and application thereof are provided. The liquid explosive includes raw materials in parts by mass: a main explosive with positive oxygen balance, a guest regulator and isolation microcapsules; the main explosive with the positive oxygen balance includes raw materials in parts by mass: monomethylamine nitrate, ammonium nitrate, sodium nitrate, water, guar gum, sodium nitrite, a high-temperature resistant regulator with a low detonation velocity and a surfactant; the guest regulator includes raw materials in parts by mass: a reducing agent and a density regulator; the isolation microcapsules include raw materials in parts by mass: porous hollow microbeads, a pore plugging agent and wall materials of pressure-resistant microcapsules; the guest regulator exists in the porous hollow microbeads of the isolation microcapsules.

Abstract: Disclosed are a trifluoromethyl alkenylphosphonate derivative and preparation method therefor. The preparation method comprises the following steps: dissolving an acetylene derivative, an iodine compound, and a phosphorus reagent in a solvent for reaction at the temperature from the room temperature to 100° C. to obtain the trifluoromethyl alkenylphosphonate derivative. In the present invention, the acetylene derivative is used as a starting material, and the raw materials are easily available and diversified; products obtained by using the method of the present invention have various types and can be directly used and also used for other further reactions; moreover, the method disclosed in the present invention has the advantages of short steps, mild reaction conditions, simple reaction operation and post-treatment processes, and high yield, and is suitable for large-scale production.

Abstract: Provided are fusion proteins that include an apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) and a clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) protein, optionally further with uracil glycosylase inhibitor (UGI). Such a fusion protein is able to conduct base editing in DNA by deaminating cytosine to uracil, even when the cytosine is in a GpC context or is methylated.

Abstract: The present disclosure relates to a growth hormone fusion protein and a preparation method and use thereof. The growth hormone fusion protein includes: a double-stranded structure having a first constant region Fc segment and a second constant region Fc segment; and a growth hormone linked to the first constant region Fc segment, the growth hormone has no methionine at an N-terminus thereof, and the growth hormone fusion protein was expressed by a non-mammalian cell expression system. According to the present disclosure, by adopting the fusion of the growth hormone and the double-stranded structure, the in vivo half-life of the growth hormone can be prolonged, and since each double-stranded structure only carries one growth hormone, the active site of the growth hormone is not affected by steric hindrance, and stronger activity is provided, and since the N-terminus of the growth hormone has no methionine, higher safety is provided.

Abstract: Disclosed is a guiding and injecting integrated mechanism for continuous conduit, belonging to underground exploration technical field. The mechanism comprises a pair of chain wheel and chain clamping assemblies used for clamping conduit and pulling conduit to go down or out of well. A conduit guiding channel for conduit to pass through is formed between the pair of chain wheel and chain clamping assemblies, and an inlet and an outlet of the conduit guiding channel are not situated in line. The conduit guiding channel is arc-shaped and each of the two chain wheel and chain clamping assemblies comprises a chain wheel set, chains, clamping blocks mounted on the chain, and a pushing plate for pressing the clamping blocks. Further, clamping surfaces of the clamping blocks have a certain curvature with respect to guiding direction.

Abstract: A moon-based in-situ condition-preserved coring multi-stage large-depth drilling system and method therefor. The system includes a rotary plate provided inside a lander, an in-situ condition-preserved coring tool provided on a surface of the rotary plate, a space frame provided on a surface of the rotary plate, a working platform provided on a top of the space frame, a mechanical arm provided on a bottom surface of the working platform, and a camera provided on the bottom surface of the working platform, the mechanical arm is fixedly connected to the working platform, and the camera is fixedly connected to the working platform. By controlling the mechanical arm to place the in-situ condition-preserved coring tool on the moon surface, and using the in-situ condition-preserved coring tool to sample the lunar soil on the moon surface, the coring operation problem of the lunar soil is solved.

Abstract: Disclosed is a continuous conduit apparatus based on guiding and injecting integrated mechanism, which comprises a straightening apparatus and a pair of sprocket and chain clamping assemblies. The pair of sprocket and chain clamping assemblies are configured to clamp the conduit and pull the conduit to go downwards a well or upwards a lifting direction. Between the pair of sprocket and chain clamping assemblies, a conduit guide channel applied for the conduit to passing through is formed. An inlet and an outlet of the conduit guide channel are not situated in a straight line, and the straightening apparatus are configured to straighten the conduit. Each of the two sprocket and chain clamping assemblies comprises a sprocket set, a chain, a plurality of clamping blocks mounted on the chain, and a pushing plate configured to press the clamping blocks.

Abstract: An indicator light circuit configured for a micro-current comprises an indicator light module, a logic controller, and a sampling circuit. The logic controller is configured to compare a sample voltage generated by the micro-current on the sampling circuit with a first preset threshold voltage. When the sample voltage is greater than the first preset threshold voltage, the logic controller outputs a control signal to the indicator light module to drive an indicator light of the indicator light module to be turned on.

Abstract: A constant current output circuit configured for a micro-current comprises a voltage boosting module and a logic controller. An input terminal of the voltage boosting module is connected to a power source, and an output terminal of the logic controller is connected to the input terminal of the voltage boosting module. The logic controller is configured to compare a sample voltage generated by the micro-current on a sampling resistor with a first threshold voltage, and when the sample voltage is less than the first threshold voltage, the logic controller drives the voltage boosting module to boost an output voltage until the sample voltage is increased to be greater than the first threshold voltage.

Abstract: Disclosed is a continuous conduit operation apparatus, which comprises a folding frame and a guiding and injecting integrated mechanism configured to pull the conduit to go downwards a well or upwards a lifting direction. The folding frame comprises a base, a mounting frame connected to the base in a movable connection, and a telescopic mechanism configured to rotate the mounting frame in a vertical plane around a position of the movable connection. One end of the telescopic mechanism is movably connected to the base, another end of the telescopic mechanism is movably connected to the mounting frame. The guiding and injecting integrated mechanism is arranged on the mounting frame. The present disclosure integrates the guiding function and the injection function to reduce the height of the apparatus and is suitable for operation environment with limited space and height.

Abstract: Disclosed is a guiding and injecting integrated mechanism for continuous conduit, belonging to underground exploration technical field. The mechanism comprises a pair of chain wheel and chain clamping assemblies used for clamping conduit and pulling conduit to go down or out of well. A conduit guiding channel for conduit to pass through is formed between the pair of chain wheel and chain clamping assemblies, and an inlet and an outlet of the conduit guiding channel are not situated in line. The conduit guiding channel is arc-shaped and each of the two chain wheel and chain clamping assemblies comprises a chain wheel set, chains, clamping blocks mounted on the chain, and a pushing plate for pressing the clamping blocks. Further, clamping surfaces of the clamping blocks have a certain curvature with respect to guiding direction.

Abstract: The invention discloses a visualization system with a real-time imaging function, comprising: a receiving end, a light source, an imaging system, and a display device. The light source comprises a red light source and a fluorescence excitation light source; the imaging system comprises a red light image sensor and a fluorescence image sensor to process a signal to output a real-time visualization signal to the display device. Through the technical scheme, the visualization system can provide sufficient background information and obtain a clear and complete real-time image for a surgeon only by using a specific band of red light to illuminate a surgical scene, the visualization system is simple in whole structure, is convenient in a control method, is simple and highly effective in the imaging process procedure, has a good use experience while the manufacturing and maintenance costs are low, and has a very high applicability and popularization.

Abstract: A system and method for transmission of a signal for a powered assistive device has a sensor node with a wireless transmitter adapted for digitally transmitting a transmitted signal, the sensor node adapted for receiving and monitoring a sensor signal from a sensor attached to a user, and a master node with a controller and a wireless receiver for receiving the transmitted signal from the wireless transmitter. The master node processes the transmitted signal and communicates a control signal to the powered assistive device. The wireless transmitter transmits the transmitted signal at a first rate when the wireless transmitter adapted to transmit the transmitted signal at a first rate when the sensor signal is indicative of the rest state and to transmit the transmitted signal at a second rate when the sensor signal is indicative of the active state, the second rate being greater than the first rate.

Abstract: An internal blowout-prevention gas-retaining connector has a body mounted at the bottom of a drill pipe. The body includes a valve pipe section and a connecting pipe section arranged from top to bottom. The bottom of the valve pipe section is inserted into the top of the connecting pipe section. The blowout-prevention valve seat is provided at a bottom end of the valve pipe section while a blowout-prevention valve bonnet is provided on a bottom surface of the valve pipe section. The edge of the blowout-prevention valve bonnet is rotatably connected to a bottom surface edge of the valve pipe section. A torsion spring is provided on a bottom surface of the blowout-prevention valve bonnet. One end of the torsion spring is connected to the bottom surface of the blowout-prevention valve bonnet while the other end is connected to the inner wall of the connecting pipe section.

Abstract: A heart valve prosthesis anchored to an interventricular septum. The heart valve prosthesis includes a valve supporting frame and a fixing device. The valve supporting frame includes a valve stitching section and an artificial valve. The artificial valve is fixedly connected to the valve stitching section. The fixing device includes a fixing and supporting section and a fixing member. One end of the fixing and supporting section is connected to a proximal end of the valve stitching section, and another end of the fixing and supporting section is connected to the interventricular septum of a patient by the fixing member, to support the heart valve prosthesis and prevent the heart valve prosthesis from axially moving.

Abstract: A prediction device extracts each predictive feature vector expressing a feature from a peptide that is a target for biostability prediction. The prediction device generates a predicted value of biostability of the prediction target cyclic peptide by inputting plural predictive feature vectors into a trained model pre-trained to output a predicted value of peptide biostability.

Abstract: A moon-based in-situ condition-preserved coring multi-stage large-depth drilling system and method therefor. The system includes a rotary plate provided inside a lander, an in-situ condition-preserved coring tool provided on a surface of the rotary plate, a space frame provided on a surface of the rotary plate, a working platform provided on a top of the space frame, a mechanical arm provided on a bottom surface of the working platform, and a camera provided on the bottom surface of the working platform, the mechanical arm is fixedly connected to the working platform, and the camera is fixedly connected to the working platform. By controlling the mechanical arm to place the in-situ condition-preserved coring tool on the moon surface, and using the in-situ condition-preserved coring tool to sample the lunar soil on the moon surface, the coring operation problem of the lunar soil is solved.

Abstract: A system and method for transmission of a signal for a powered assistive device has a sensor node with a wireless transmitter adapted for digitally transmitting a transmitted signal, the sensor node adapted for receiving and monitoring a sensor signal from a sensor attached to a user, and a master node with a controller and a wireless receiver for receiving the transmitted signal from the wireless transmitter. The master node processes the transmitted signal and communicates a control signal to the powered assistive device. The wireless transmitter transmits the transmitted signal at a first rate when the wireless transmitter adapted to transmit the transmitted signal at a first rate when the sensor signal is indicative of the rest state and to transmit the transmitted signal at a second rate when the sensor signal is indicative of the active state, the second rate being greater than the first rate.