Abstract: A drug delivery implant may include an implant body and a core comprising a pharmaceutical agent. The core can be located within the implant body that extends longitudinally and circumferentially around the core. The implant body can also define an aperture that exposes a first surface of the core. A method for treating a mammal to obtain a desired physiological or pharmacological effect by injecting such a drug delivery implant into a mammal in need of treatment is also disclosed.

Abstract: The field is related to plant breeding and methods of identifying and selecting plants with resistance to southern corn rust. Provided are methods to identify novel genes that encode proteins providing plant resistance to southern corn rust and uses thereof. These disease resistant genes are useful in the production of resistant plants through breeding, transgenic modification, or genome editing.

Abstract: A molecular marker for identifying DNA methylation and thereby detecting the benignity or malignancy of a lung nodule is disclosed. The molecular marker for identifying DNA methylation includes the sequence of, or the completely complementary sequence to, SEQ ID NO:6 or a continuous fragment of at least 55% of the full length of the sequence of, or the completely complementary sequence to, SEQ ID NO:6. Also disclosed are applications of the molecular marker for identifying DNA methylation, including a corresponding detection reagent kit and a corresponding detection method. The disclosed molecular marker combinations for identifying DNA methylation are highly correlated to lung cancer, are highly sensitive and specific when used to detect the benignity or malignancy of a lung nodule, and can increase the detection rate of malignant lung nodules while lowering the false positive rate.

Abstract: Formulations and intravitreal implants containing nintedanib can be used in methods for the treatment of back-of-the-eye diseases.

Abstract: An air conditioner and a method for controlling air conditioner communication are disclosed. The air conditioner includes an indoor unit, an outdoor unit, and a temperature protector. The indoor unit includes an indoor control device and an indoor communication device. The outdoor unit includes an outdoor control device and an outdoor communication device. The temperature protector includes a temperature control device and a temperature control communication device. The temperature control device is configured to output a temperature control setting parameters. The temperature control communication device is coupled with the temperature control device.

Abstract: This invention relates to a bioerodible drug delivery device that can be implanted in a patient at or near an area in need of treatment. The bioerodible drug delivery device can be used to deliver a wide variety of different pharmaceutically active agents, and can do so at a controlled rate and over an extended period of time. The bioerodible drug delivery device includes a bioerodible polymeric outer housing with one or more delivery ports for delivering the pharmaceutically active agent(s) contained therein. The polymer used as the bioerodible polymeric outer housing is not substantially degraded during the dosing of the pharmaceutically active agent(s) in the bioerodible drug delivery device. The invention also provides methods of making the bioerodible drug delivery device and using it for the treatment of diseases and disorders.

Abstract: Described are self-learning systems and methods for adaptive management of memory resources within a memory hierarchy. Memory allocations associated with different active functions are organized into blocks for placement in alternative levels in a memory hierarchy optimized for different metrics of e.g. cost and performance. A host processor monitors a performance metric of the active functions, such as the number of instructions per clock cycle, and reorganizes the function-specific blocks among the levels of the hierarchy. Over time, this process tends toward block organizations that improve the performance metric.

Abstract: Disclosed is a high-magnetic-induction oriented silicon steel, wherein the chemical elements thereof are, in mass percentage: Si: 2.0-4.0%; C: 0.03-0.07%; Al: 0.015-0.035%; N: 0.003-0.010%; Nb: 0.0010-0.0500%, the balance being Fe and inevitable impurities. The manufacturing method for the high-magnetic-induction oriented silicon steel includes the steps of: (1) smelting and casting; (2) heating a slab; (3) hot rolling; (4) cold rolling; (5) decarbonizing and annealing; (6) nitriding treatment; (7) applying an MgO coating; (8) high temperature annealing; and (9) applying an insulating coating; wherein a high-magnetic-induction oriented silicon steel is obtained by the manufacturing method, having an average primary grain size of 14-22 ?m and a primary grain size variation coefficient of higher than 1.

Abstract: This invention relates to a bioerodible drug delivery device that can be implanted in a patient at or near an area in need of treatment. The bioerodible drug delivery device can be used to deliver a wide variety of different pharmaceutically active agents, and can do so at a controlled rate and over an extended period of time. The bioerodible drug delivery device includes a bioerodible polymeric outer housing with one or more delivery ports for delivering the pharmaceutically active agent(s) contained therein. The polymer used as the bioerodible polymeric outer housing is not substantially degraded during the dosing of the pharmaceutically active agent(s) in the bioerodible drug delivery device. The invention also provides methods of making the bioerodible drug delivery device and using it for the treatment of diseases and disorders.

Abstract: An apparatus and a method for rapidly heating cold-rolled strip steel (10). The apparatus for rapidly heating cold-rolled strip steel (10) comprises a heating zone, a soaking zone, and a cooling zone, and the heating zone is sequentially divided into a first heating section (1), a second heating section (2), a third heating section (3), and a fourth heating section (4) along a moving direction of the strip steel (10) to be heated, the first heating section (1) and the fourth heating section (4) being radiant heating sections, and the second heating section (2) and the third heating section (3) being inductive heating sections. The method for rapidly heating cold-rolled strip steel (10) uses the apparatus for rapidly heating cold-rolled strip steel (10) to heat the strip steel (10).

Abstract: This invention relates to a bioerodible drug delivery device that can be implanted in a patient at or near an area in need of treatment. The bioerodible drug delivery device can be used to deliver a wide variety of different pharmaceutically active agents, and can do so at a controlled rate and over an extended period of time. The bioerodible drug delivery device includes a bioerodible polymeric outer housing with one or more delivery ports for delivering the pharmaceutically active agent(s) contained therein. The polymer used as the bioerodible polymeric outer housing is not substantially degraded during the dosing of the pharmaceutically active agent(s) in the bioerodible drug delivery device. The invention also provides methods of making the bioerodible drug delivery device and using it for the treatment of diseases and disorders.

Abstract: An apparatus and a method for rapidly heating cold-rolled strip steel (10). The apparatus for rapidly heating cold-rolled strip steel (10) comprises a heating zone, a soaking zone, and a cooling zone, and the heating zone is sequentially divided into a first heating section (1), a second heating section (2), a third heating section (3), and a fourth heating section (4) along a moving direction of the strip steel (10) to be heated, the first heating section (1) and the fourth heating section (4) being radiant heating sections, and the second heating section (2) and the third heating section (3) being inductive heating sections. The method for rapidly heating cold-rolled strip steel (10) uses the apparatus for rapidly heating cold-rolled strip steel (10) to heat the strip steel (10).

Abstract: Described are self-learning systems and methods for adaptive management of memory resources within a memory hierarchy. Memory allocations associated with different active functions are organized into blocks for placement in alternative levels in a memory hierarchy optimized for different metrics of e.g. cost and performance. A host processor monitors a performance metric of the active functions, such as the number of instructions per clock cycle, and reorganizes the function-specific blocks among the levels of the hierarchy. Over time, this process tends toward block organizations that improve the performance metric.

Abstract: The present invention relates to sustained release drug delivery systems, medical devices incorporating said systems, and methods of use and manufacture thereof. The inventive systems feature bioerodible drug delivery devices that include biocompatible solid and biocompatible fluid compositions to achieve desired sustained release drug delivery.

Abstract: The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the drug-eluting particle of the invention comprises a biodegradable porous silicon body, a reservoir formed within the porous silicon body having at least one opening to an exterior of the body, wherein the reservoir contains a therapeutic or diagnostic agent, and an agent-permeable seal disposed over the at least one opening. The invention further provides a method for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle of the invention. The invention also provides methods of fabricating a drug-eluting particle for releasing therapeutic agents.

Abstract: The present disclosure provides a method for processing an acid gas, comprising: using a processor 1 for receiving and processing the acid gas to obtain a gas phase stream 1 and a liquid phase stream 2, wherein the stream 2 is partially or completely recycled to the processor 1; using a processor 2 for processing the stream 1 from the processor 1 to obtain a gas phase stream 3 and a liquid phase stream 4; using a processor 3 for processing the stream 3 from the processor 2 to obtain a gas phase stream 5 and a liquid phase stream 6; and using a processor 4 for receiving the stream 43 from the processor 2 and using the stream 43 as a processing solution for processing the stream 5 from the processor 3 to obtain a gas phase stream 7 and a liquid phase stream 8, which can be divided into two sub-streams including a stream 81 and a stream 82. The present disclosure further provides an apparatus for processing an acid gas.

Abstract: The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the drug-eluting particle of the invention comprises a biodegradable porous silicon body, a reservoir formed within the porous silicon body having at least one opening to an exterior of the body, wherein the reservoir contains a therapeutic or diagnostic agent, and an agent-permeable seal disposed over the at least one opening. The invention further provides a method for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle of the invention.

Abstract: The invention provides liquid controlled-release drug delivery compositions which gel upon injection into the body to form, in situ, controlled-release drug implants. The compositions of the invention feature a gel-forming polymer that is insoluble in water, a polyethylene glycol solvent in which the polymer is dissolved, and the drug substance to be delivered.

Abstract: The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the drug-eluting particle of the invention comprises a biodegradable porous silicon body, a reservoir formed within the porous silicon body having at least one opening to an exterior of the body, wherein the reservoir contains a therapeutic or diagnostic agent, and an agent-permeable seal disposed over the at least one opening. The invention further provides a method for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle of the invention. The invention also provides methods of fabricating a drug-eluting particle for releasing therapeutic agents.

Abstract: The present disclosure provides a reactor for at least two liquid materials, comprising an enclosed reactor housing; a feeding tube having liquid material inlets for receiving corresponding liquid materials respectively; a distribution tube communicating with the feeding tube and extending into the reactor housing, the distribution tube being provided with a plurality of distribution holes in the region thereof extending into the reactor housing; a rotating bed in form of a hollow cylinder, which is disposed in the reactor housing via a fixing mechanism, thus dividing inner cavity of the reactor housing into a central area and an outer area, the rotating bed being capable of rotating driven by a driving mechanism; and a material outlet provided in a lower portion of the reactor housing for outputting product after reaction.