Patents by Inventor Jianjun Wang

Jianjun Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10640751
    Abstract: A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPS cells formed using this method and uses thereof.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: May 5, 2020
    Assignee: Wayne State University
    Inventors: Jianjun Wang, Qianqian Li
  • Publication number: 20200108879
    Abstract: A track link rail surface and roller interface includes a first roller including a cylindrical configuration defining a radial direction, a longitudinal axis, a circumferential direction, and a plane containing the radial direction and the longitudinal axis. The first roller includes a first track link rail engaging surface including a first concave arcuate surface defining a first concave radius of curvature. The interface includes a first track link including a first track link rail surface including a first convex arcuate surface defining a first convex radius of curvature that is less or equal to the first concave radius of curvature.
    Type: Application
    Filed: October 5, 2018
    Publication date: April 9, 2020
    Applicant: Caterpillar Inc.
    Inventors: Matthew William Trone, Jianjun Wang
  • Patent number: 10598979
    Abstract: A color filter substrate includes a base substrate and a color filter formed on the base substrate, wherein the color filter includes at least one color area; the color filter substrate further includes at least one of at least one kind of fluorescent powder or at least one antireflective film, wherein each kind of fluorescent powder in the at least one kind of fluorescent powder corresponds to one color area in the color filter; each antireflective film in the at least one antireflective film corresponds to one color area in the color filter, the fluorescent powder is configured to convert light, of which a color is different from a color of a corresponding color area, in incident light into light of which a color is the same with the color of the corresponding color area.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: March 24, 2020
    Assignees: BOE TECHNOLOGY GROUP CO., LTD., BEIJING BOE DISPLAY TECHNOLOGY CO., LTD.
    Inventor: Jianjun Wang
  • Patent number: 10588853
    Abstract: The invention pertains to a lipid-based microbubble stably binding a plurality of nucleic acids, and a method of delivering the microbubble and nucleic acids to a specific target site using ultrasound. The delivered nucleic acids create transgenic cells (i.e., for example, a transgenic tumor cell), wherein the transgenic cell expresses the proteins encoded by the delivered nucleic acids. This technology provides a significant improvement for microbubble-drug delivery platforms as known microbubble do not efficiently bind nucleic acids. The improvements described herein include but are not limited to identifying proper lipid proportionality ratios and/or cationic surfactant layers that provide an optimum mechanical index compatible with ultrasonics. Microbubble perfusion and/or nucleic acid delivery may be performed by a combination of imaging and ultrasound/microbubble targeted delivery to simultaneously perform low power two-dimensional imaging and high power microbubble destruction.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: March 17, 2020
    Assignee: University Of Pittsburgh—Of The Commonwealth System Of Higher Education
    Inventors: Flordeliza Villanueva, Andrew Carson, Charles F McTiernan, Jianjun Wang
  • Publication number: 20200066221
    Abstract: A compensation device, a display device and a method for compensating common electrode voltage are provided in the embodiments of the present disclosure. A compensation device for a display panel according to an embodiment includes a compensation circuit, a comparison circuit, and an adjustment circuit. The compensation circuit generates a common electrode compensation signal to be provided to the display panel based on a common electrode input signal for providing a common electrode voltage to the display panel and a common electrode feedback signal from the display panel. The comparison circuit compares the common electrode compensation signal with the common electrode feedback signal. The adjustment circuit adjusts the common electrode compensation signal according to the comparison result of the comparison circuit.
    Type: Application
    Filed: July 24, 2017
    Publication date: February 27, 2020
    Inventors: Jianjun WANG, Long YAN, Chunyang NIE, Ke DAI
  • Patent number: 10570736
    Abstract: In one embodiment, the present disclosure provides a robot automated mining method. In one embodiment, a method includes a robot positioning a charging component for entry into a drill hole. In one embodiment, a method includes a robot moving a charging component within a drill hole. In one embodiment, a method includes a robot filling a drill hole with explosive material. In one embodiment, a method includes operating a robot within a mining environment.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: February 25, 2020
    Assignee: ABB Schweiz AG
    Inventors: Jianjun Wang, Carlos Martinez, Carlos Morato, Biao Zhang, Thomas Fuhlbrigge, Will Eakins, Sang Choi, Daniel Lasko, Jan Nyqvist, Remus Boca
  • Patent number: 10548983
    Abstract: Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: February 4, 2020
    Assignee: Wayne State University
    Inventors: Jianjun Wang, Qianqian Li, Michael Chopp, Feng Jiang, Guojun Wu
  • Publication number: 20200020264
    Abstract: This disclosure discloses a shift register, a method for driving the same, a gate driver circuit, and a display device. The shift register includes an input circuit, a reset circuit, a first control circuit, a first output circuit, and a second output circuit, where the first output circuit includes two output channels, where one channel is that under the joint control of signals of a first clock signal terminal and a first node, a signal of a first clock signal terminal is provided to a drive signal output terminal of the shift register, and the other channel is that under the joint control of signals of the second clock signal terminal and the first node, a signal of a second clock signal terminal is provided to the drive signal output terminal, and the first output circuit cooperates with the other four circuits so that these two channels can operate alternately to thereby avoid current from flowing through only one of the channels so as to improve the service lifetime of the shift register.
    Type: Application
    Filed: June 29, 2018
    Publication date: January 16, 2020
    Inventors: Kangxi Chen, Min Wang, Hui Dong, Hongjun Wang, Jianjun Wang
  • Publication number: 20200001458
    Abstract: A robot is configured to perform a task on an object using a method for generating a 3D model sufficient to determine a collision free path and identify the object in an industrial scene. The method includes determining a predefined collision free path and scanning an industrial scene around the robot. Stored images of the industrial scene are retrieved from a memory and analyzed to construct a new 3D model. After an object is detected in the new 3D model, the robot can further scan the image in the industrial scene while moving along a collision free path until the object is identified at a predefined certainty level. The robot can then perform a robot task on the object.
    Type: Application
    Filed: June 27, 2018
    Publication date: January 2, 2020
    Inventors: Biao Zhang, Remus Boca, Carlos W. Morato, Carlos Martinez, Jianjun Wang, Zhou Teng, Jinmiao Huang, Magnus Wahlstrom, Johnny Holmberg
  • Publication number: 20190392744
    Abstract: The embodiments of the present disclosure discloses a signal processing method, a timing control circuit, and a system. The signal processing method comprises: receiving a data enable signal or monitoring an estimated data enable signal; and controlling an activate timing of a mask signal according to the data enable signal or the estimated data enable signal. According to the embodiments of the present disclosure, frame-to-frame overlap can be eliminated, thereby solving display anomalies due to undesired overlapping of signals, and also enabling sufficient noise reduction for GOA units under normal input condition, thereby extending the life expectancy of systems such as displays.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 26, 2019
    Inventors: Jianjun WANG, Min WANG, Hui DONG
  • Publication number: 20190336562
    Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.
    Type: Application
    Filed: July 22, 2019
    Publication date: November 7, 2019
    Inventors: Jianjun Wang, Qianqian Li
  • Publication number: 20190318796
    Abstract: A shift register unit is provided, which includes an input circuit, a first output circuit and a first output signal adjustment circuit. The input circuit is configured for receiving an input signal from an input terminal and controlling an electrical signal of a first node based on the input signal. The first output circuit is configured for outputting a first output signal at a first output terminal of the shift register unit based on a first clock signal under control of the electrical signal of the first node. The first output signal adjustment circuit is configured for providing a first reference signal to the first output terminal under control of the second clock signal so as to decrease an amplitude of the first output signal.
    Type: Application
    Filed: January 10, 2019
    Publication date: October 17, 2019
    Inventors: Xiong XIONG, Xiaozhe ZHANG, Yudong LIU, Jianjun WANG
  • Publication number: 20190291855
    Abstract: A multi-rotor aircraft (100) is provided, comprising: a main aircraft assembly (10) comprising a first magnetic medium (13), a main housing (11), and a control motherboard accommodated in the main housing (11), wherein the first magnetic medium (13) is provided on the main housing (11), a slot (1120) is further provided on the main housing (11), and a connection point of the control motherboard is provided in the slot (1120); and a plurality of rotor systems (20), wherein each of the plurality of rotor systems comprises a second magnetic medium (23), a rotor mechanism (21), and a rotor protection cover (22) that is of a hollow annular structure and is fixed outside the rotor mechanism (21), wherein the second magnetic medium (23) is fixed to the rotor protection cover (22) and attracting the first magnetic medium (13), and a pin (2200) matching the slot (1120) is further provided on the rotor protection cover (22).
    Type: Application
    Filed: May 18, 2016
    Publication date: September 26, 2019
    Inventor: Jianjun WANG
  • Patent number: 10413278
    Abstract: Various methods of performing ultrasound contrast assisted therapy are provided. One such method includes delivering a plurality of microbubble-based ultrasound contrast agents to a target area and disrupting the microbubble-based ultrasound contrast agents by delivering tone bursts of ultrasound to the target area. The oscillation of the microbubble-based ultrasound contrast agents can be achieved by delivering ultrasound tone bursts of greater than 5 acoustic cycles with a pulse repetition frequency of between 0.01 and 20 Hz, with pressure greater than 0.3 MPa.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: September 17, 2019
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Xucai Chen, Jianjun Wang, John J. Pacella, Flordeliza S. Villanueva
  • Publication number: 20190271866
    Abstract: An anti-peeping device, an anti-peeping display, and a control method. The anti-peeping device comprises an external light source, a grating mirror structure, and a first controller coupled to the grating mirror structure. The external light source is configured to emit light towards the grating mirror structure, and the first controller is configured to control the grating mirror structure to rotate such that light emitted from the external light source towards the grating mirror structure is reflected to a first direction by the grating mirror structure, the first direction deviating from a normal perpendicular to the horizontal plane of the grating mirror structure.
    Type: Application
    Filed: August 24, 2018
    Publication date: September 5, 2019
    Inventors: Yupeng WANG, Jianjun WANG, Lidong YAN, Jiliang ZHANG
  • Publication number: 20190251865
    Abstract: An electronic building block system includes at least one set of power source modules (10) for supplying electric energy, at least one set of input modules (20) electrically connected to the power source modules (10) and used for inputting data and signals, at least one set of output modules (30) electrically connected to the power source modules (10) and used to receive data and signal control of the input modules (20) to output corresponding signals and at least one communication module (40) selectively connected to the power source modules (10); and the communication module (40) is connected or disconnected so that communication between the electronic building block system and an external terminal (50) is connected to or disconnected, so that the electronic building block system is in a non-programmable state or a programmable state.
    Type: Application
    Filed: February 16, 2017
    Publication date: August 15, 2019
    Inventor: Jianjun WANG
  • Patent number: 10378353
    Abstract: In one embodiment, the present disclosure provides a robot automated mining method. In one embodiment, a method includes a robot positioning a charging component for entry into a drill hole. In one embodiment, a method includes a robot moving a charging component within a drill hole. In one embodiment, a method includes a robot filling a drill hole with explosive material. In one embodiment, a method includes operating a robot within a mining environment.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: August 13, 2019
    Assignee: ABB Schweiz AG
    Inventors: Jianjun Wang, Carlos Martinez, Carlos Morato, Biao Zhang, Thomas Fuhlbrigge, Will Eakins, Sang Choi, Daniel Lasko, Jan Nyqvist, Remus Boca
  • Patent number: 10357532
    Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery, a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: July 23, 2019
    Assignee: Wayne State University
    Inventors: Jianjun Wang, Qianqian Li
  • Patent number: 10349035
    Abstract: Automatic scanning and representing an environment having a plurality of features, for example, includes scanning the environment along a scanning path, interspersing a plurality of localized scanning of the plurality of features in the environment during the scanning along the scanning path of the environment wherein the interspersed localized scanning of the plurality of features in the environment being different from the scanning the environment along the scanning path, and obtaining a representation of at least a portion of the environment based on the scanning of the environment and the interspersed localized scanning of the plurality of features in the environment.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: July 9, 2019
    Assignee: ABB Schweiz AG
    Inventors: Jianjun Wang, Biao Zhang, Carlos Martinez, Carlos W. Morato, Remus Boca
  • Publication number: 20190204694
    Abstract: The present disclosure discloses an electrostatic protection method, an electrostatic protection apparatus and a liquid crystal display. The electrostatic protection method includes: monitoring an interface signal of a timing control circuit and/or a level conversion circuit to determine whether the monitored signal is subjected to electrostatic interference; and when the electrostatic interference is detected, adjusting a timing control signal output by the timing control circuit to a gate driving circuit of an array substrate, wherein the level conversion circuit connects the timing control circuit to the gate driving circuit of the array substrate, and is configured to perform level conversion on an output signal output by the timing control circuit to the gate driving circuit of the array substrate.
    Type: Application
    Filed: April 20, 2018
    Publication date: July 4, 2019
    Inventors: Jianjun Wang, Yuanyuan Liu, Min Wang, Rui Ma