Abstract: A full continuous-flow preparation method of (+)-biotin, including: subjecting a cyclic anhydride and a chiral biphenyl propylene glycol to asymmetric ring-opening reaction to produce a first intermediate, which undergoes selective reduction with a borohydride and cyclization with an inorganic mineral acid to produce (3aS, 6aR)-lactone; subjecting the (3aS, 6aR)-lactone and a sulfenylating reagent to sulfenylation to produce (3aS, 6aR)-thiolactone, which undergoes Fukuyama coupling with a zinc reagent in the presence of a palladium catalyst and elimination reaction in the presence of an inorganic mineral acid to produce an alkenyl valerate compound; subjecting the alkenyl valerate compound to reduction in the presence of a Pd/C catalyst to produce a valerate ester, which undergoes hydrolysis to produce a valeric acid salt; and subjecting the valeric acid salt to debenzylation in the presence of an inorganic mineral acid to produce the target product (+)-biotin.

Abstract: A micro-zone soil sampling apparatus and method for different contamination situations. The apparatus includes an uncovered cylinder and a plurality of circular separators. The circular separators are horizontally arranged in a hollow inner cavity of the uncovered cylinder, and are removably connected to an inner wall of the uncovered cylinder. Each circular separator includes a plurality of inner rings arranged coaxially, an outer ring coaxially arranged outside the inner rings, and a soil-bearing net. Each circular separator is divided into multiple hollow spaces by the inner rings and the outer ring. The inner rings made of a permeable membrane material and the outer ring made of a rigid material both have a certain thickness. The soil-bearing net is fittedly fixed on a bottom of each circular separator. A plurality of spokes passing through a center of the soil-bearing net are fixedly arranged on the soil-bearing net. A micro-zone soil sampling apparatus and method for different contamination situations.

Abstract: A method for preparing L-carnitine using a micro-reaction system. (R)-4-halo-3-hydroxybutyrate was subjected to quaternization and hydrolysis in an aqueous trimethylamine solution in the presence of an inorganic base in a micro-channel reactor to produce the L-carnitine.

Abstract: An interferometric demodulation system for a large capacity fiber grating sensing network is provided by the present disclosure, comprising: a continuous light output end of the nanoscale wide-spectrum light source is connected to an input end of the pulse optical modulator, an output end of the reference grating is connected to an input end of the grating array sensing network, and a third communication end of the optical circulator is connected to an input end of the optical amplifier, an output end of the optical amplifier is connected to an input end of the Mach-Zehnder interferometer, three-channel signal output ends of the Mach-Zehnder interferometer are respectively connected to signal input ends corresponding to the embedded signal processor through the photoelectric converter, and the embedded signal processor controls the heating device to control a temperature of an any one of interference arms of the Mach-Zehnder interferometer.

Abstract: A bifunctional catalyst and a preparation method therefor are provided. The bifunctional catalyst is prepared by providing carbon matrix, adding 0.01-10 mol/L platinum containing solution, 0.01-10 mol/L palladium containing solution, 0.01-10 mol/L silver containing solution, and 0.01-15 mol/L sodium citrate trihydrate solution to the carbon matrix for reacting at 20° C. to 80° C. for 0.5 h to 24 h to obtain a mixed solution, and adding reducing agent to the mixed solution for reacting for 0.5 h to 30 h, and centrifuging and drying so as to obtain the bifunctional catalyst.

Abstract: A method for simultaneously determining fat-soluble vitamins and carotenoids in serum, and belonging to the technical field of analytical chemistry, includes an ionic liquid (IL) or a binary mixed solvent composed of an IL and another solvent is adopted as an extractant; the biological samples are pre-treated by liquid-liquid extraction (LLE) and then detected by high-performance liquid chromatography (HPLC); retinyl acetate and trans-?-apo-8?-carotenal are adopted as the internal standards for fat-soluble vitamins and carotenoids, respectively; and the internal standard method is adopted to establish standard curves for quantification based on the retention time and the UV-Vis absorption spectrum. Compared with the existing methods, in the disclosure, the pretreatment process is simple and easy to be conducted, the sample can be prepared in a short time, and the toxic and harmful organic solvent is used at a reduced amount.

Abstract: A TOF depth measuring device includes: an emission module projects a dot matrix pattern onto a target object, and an acquisition module includes an image sensor configured to receive reflected optical signals reflected by the target object. First pixels in the pixel array detect reflected optical signals of real light spots reflected by the target object, and second pixels in the pixel array detect reflected optical signals of real light spots reflected more than once. The TOF depth measuring device further includes a processor, connected to the emission module and the acquisition module, filters the first reflected optical signal to obtain a third reflected optical signal, and calculate a phase difference based on the third reflected optical signal to obtain a first depth map of the target object.

Abstract: An enzyme-catalyzed synthesis of (1S,5R)-bicyclolactone. A first genetically-engineered bacterium containing Baeyer-Villiger monooxygenase gene and a second genetically-engineered bacterium containing glucose dehydrogenase gene are constructed and then suspended with culture medium to prepare a first suspension and a second suspension, respectively. The first and second suspensions are centrifuged to respectively produce a first supernatant containing Baeyer-Villiger monooxygenase and a second supernatant containing glucose dehydrogenase, which are mixed. The mixed supernatant is then mixed with a raceme of a substituted bicyclo[3.2.0]-hept-2-en-6-one, a solvent, a hydrogen donor and a cofactor to perform an asymmetric Baeyer-Villiger oxidation to produce the (1S,5R)-bicyclolactone, where an amino acid sequence of the Baeyer-Villiger monooxygenase is shown in SEQ ID NO:1.

Abstract: A computer-implemented method for creating encoded data for use in a cognitive computing system. The method comprises the steps of receiving a plurality of hypervectors, each representing a respective semantic object; element-wise modular addition of two or more of the plurality of hypervectors, thereby binding the corresponding semantic objects; and vector concatenation of two or more of the plurality of hypervectors, thereby superposing the corresponding semantic objects. The method may be carried out by a cognitive processing unit that may be part of a cognitive computing system.

Abstract: Provided is a method for radially mining open-pit end slope pressed coal, including: L-shaped or U-shaped main tunnel arrangements, and radially mining; branch tunnels are formed by excavating tunnels in directions perpendicular to or obliquely crossing the main tunnel from the L-shaped or U-shaped main tunnel; In the mining method, a coal mining system and a transportation system both adopt a remote control mode, a tunneling machine excavates a tunnel to product coal; a rubber belt conveyor conveys coal; the main tunnel adopts an exhaust ventilation mode, the branch tunnels adopt a blowing ventilation mode; the lengths of the branch tunnels do not exceed a farthest control distance of a remote control system; the length of each main tunnel needs to ensure that all the end slope pressed coal is mined under the premise that the branch tunnels do not exceed the farthest control distance of the remote control system.

Abstract: This application relates to biological pharmacy and biochemical engineering, and more particularly to a method of preparing a (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound. This method includes: subjecting a 1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline raceme as a substrate to selective oxidation in the presence of a monoamine oxidase and the non-selective reduction to prepare the (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound, where the monoamine oxidase has an amino acid sequence as shown in SEQ ID NO: 1 or an amino acid sequence having an identity of more than 80% with SEQ ID NO: 1. The kinetic resolution is carried out in the presence of the monoamine oxidase as a catalyst and a reductant, and the resulting product has a high chiral purity.

Abstract: An internally injected replacement support room-type coal pillar recovery method is provided. During the recovery, the room-type coal pillars with an aspect ratio greater than 0.6 are divided into two parts: reserved coal pillars and pre-mined coal pillars. After the mining of the pre-mined coal pillars, a cemented filling material is injected into a goaf surrounded by the reserved coal pillars, and is stabilized to replace the coal pillars for support, and the reserved coal pillars are recovered. A mechanical model of the reserved coal pillars in a support overburden stage is established based on the Winkler beam theory, to obtain displacement and stress conditions of a roof of the reserved coal pillar in a support stage. A theoretical reserve-width of the reserved coal pillars is obtained according to a first strength theory of the roof and a criterion of ultimate strength of the reserved coal pillars.

Abstract: An optical fiber grating sensing method applied to small-scale fire source monitoring are provided, distinguishing two concepts of a spatial resolution and a perception resolution, under the premise of ensuring the spatial resolution of a traditional fiber Bragg grating sensing system, only increase the number of fiber Bragg gratings covered by a single pulsed optical signal without changing a pulse width of a pulsed optical signal, so as to improve the perception resolution of the system without increasing the requirements for a hardware circuit, and truly shorten an interval between adjacent fiber Bragg gratings. Improving the perception resolution of the system, which not only ensures the spatial resolution of the system, but also realizes the monitoring of small-scale fire sources; by adopting a simple feature extraction algorithm to obtain fire temperature information in different areas, the temperature detection speed of the system is fast.

Abstract: The present invention discloses an experimental device for cavitation corrosion of liquid metal, comprising a stand, and a vibration device and a lifting and rotating device separately arranged on the stand, wherein a heating device for experimental use is arranged on the vibration device; a furnace lid with a sealing ring is arranged above the heating device; a stirring mechanism is arranged on the furnace lid; the stirring mechanism is connected to a chunk below the furnace lid; a clamp is connected below the chuck, and the clamp is connected to a sample; the furnace lid is connected to the lifting and rotating device; the lifting and rotating device can control the movement of the furnace lid so that the sample is placed in the heating device; the lifting and rotating device, the stirring mechanism, the heating device and the vibration device are connected to a control system.

Abstract: An anchor determination includes: performing feature extraction on an image to be processed to obtain a first feature map of the image to be processed; performing anchor prediction on the first feature map via an anchor prediction network to obtain position information of anchors and shape information of the anchors in the first feature map, the position information of the anchors referring to information about positions in the first feature map where the anchors are generated. A corresponding anchor determination apparatus and a storage medium are also provided.

Abstract: An optical fiber grating sensing method applied to small-scale fire source monitoring are provided, distinguishing two concepts of a spatial resolution and a perception resolution, under the premise of ensuring the spatial resolution of a traditional fiber Bragg grating sensing system, only increase the number of fiber Bragg gratings covered by a single pulsed optical signal without changing a pulse width of a pulsed optical signal, so as to improve the perception resolution of the system without increasing the requirements for a hardware circuit, and truly shorten an interval between adjacent fiber Bragg gratings. Improving the perception resolution of the system, which not only ensures the spatial resolution of the system, but also realizes the monitoring of small-scale fire sources; by adopting a simple feature extraction algorithm to obtain fire temperature information in different areas, the temperature detection speed of the system is fast.

Abstract: Disclosed herein relates to organic synthesis, and more particularly to a method for preparing a key intermediate for the synthesis of statins. The key intermediate is 2-[(4R, 6S)-6-[(benzo[d]thiazol-2-ylthio)methyl]-2,2-di substituted-1,3-dioxan-4-yl] acetate of formula (I): where R1 is a C1-C8 alkyl group, a C3-C8 cycloalkyl group, a monosubstituted or polysubstituted aryl group, or monosubstituted or polysubstituted aralkyl group; R2 is hydrogen, or monosubstituted or polysubstituted C1-C3 alkyl group, or halogen; and R3 and R4 are each independently a C1-C5 alkyl group, a C3-C7 cycloalkyl group, a C3-C7 cycloalkenyl group, a C1-C3 alkoxy group, a C6-C10 aryl group, or C7-C12 aralkyl group. In the method, a halomethyl compound and a thiol reagent are subjected to nucleophilic substitution in an organic solvent to synthesize a thioether, which then undergoes ketal exchange reaction with a carbonyl compound (V) in the presence of an organic acid to obtain a target product.

Abstract: A method for correcting a phase jump caused by polarization-induced fading in optical fiber phase demodulation, including the steps of: 1, selecting a demodulated phase in the case of non-depolarization as historical sample data; 2, determining an autoregressive coefficient and a moving average coefficient of the autoregressive moving average model for the demodulated phase; 3, establishing a Kalman prediction model for the demodulated phase, and deriving recursive equations of the Kalman prediction model for the demodulated phase; and 4, judging whether a jump point exists in the actual demodulated phase, determining polarization states of lights if the jump point exists, and correcting the jump point when the polarization states of the lights are in polarization orthogonality by replacing the actual demodulated phase with a predicted phase value. The disclosure ensures the correctness of subsequent vibration-based signal processing.

Abstract: A preparation method of a direct ethanol fuel cell includes synthesizing electrolytes, preparing a cathode and an anode, and clamping the electrolytes between the cathode and the anode to get direct ethanol fuel cell. The electrolytes are synthesized by polymerizing sodium acrylate with an initiator to get a hydrogel, and the hydrogel is soaked in a harsh alkaline solution. The cathode is synthesized by coating N,S codoped carbon catalyst onto a current collector, where the N,S codoped carbon catalyst is synthesized by mixing and preheating silica powder, sucrose and trithiocyanuric acid to get a mixed powder, and mixing and heating the mixed powder with poly tetra fluoroethylene so as to get the N,S codoped carbon catalyst. The anode is synthesized by coating Pt-Ru/C catalyst onto a current collector.

Abstract: A multi-layered micro-channel mixer includes a base plate and a cover plate. Two inlet fluid reservoirs, two inlet channels, two groups of fluid distribution channel networks, two groups of process fluid channels, an impinging stream mixing chamber, a fluid mixing intensification channel and an outlet buffer reservoir are provided on the base plate. Two fluids are fed into the two inlet fluid reservoirs, respectively. The fluids then flow into the process fluid channels via the inlet channels and the multi-stage fluid distribution channel networks, respectively. Then the two fluid streams ejected from the opposing process fluid channels impinges upon each other in the impinging stream mixing chamber. The mixed fluid is subjected to vortex or secondary flow generated by the baffles or the internals in the impinging stream mixing chamber and fluid mixing intensification channel, and finally the mixed fluid is discharged through the outlet buffer reservoir.