Abstract: The present disclosure provides use of a hematopoietic cell kinase (HCK) inhibitor in preparation of a drug for treating pulmonary fibrosis, and relates to the technical field of biomedicine. In the present disclosure, idiopathic pulmonary fibrosis (IPF) model mice are used as a subject to allow research. Administration of an HCK inhibitor RK-20449 to IPF mice can effectively alleviate the progression of pulmonary fibrosis. A weight and a survival rate of the IPF mice have improved to a certain extent, and their lung function has improved significantly. The transcription levels of inflammatory factors Il-1?, Il-6, and Tnf-? in a lung tissue of the IPF mice have decreased, while the concentrations of inflammatory factors IL-1? and IL-6 in the alveolar lavage fluid have also decreased. The transcription levels of fibrosis factors Col-I and Fn-1 are decreased, the collagen-specific amino acid hydroxyproline is decreased, and the degree of lesions is alleviated.

Abstract: Provided is a use of a Galectin-1 inhibitor in preparation of a drug for treating pulmonary fibrosis. Taking silicosis model mice as a subject, administration of a Galectin-1 inhibitor OTX008 to silicosis mice can effectively alleviate the progression of pulmonary fibrosis. Studies have shown that the lung function of mice with silicosis is improved significantly; transcription levels of inflammatory factors Il-1? and Il-6 in the lung tissue of silicosis mice are decreased, concentrations of IL-1? and IL-6 in the alveolar lavage fluid are also decreased, and the infiltration of inflammatory cells is decreased. In the lung tissue of silicosis mice, the transcription levels of fibrosis factors Col-I and Fn-1 are decreased, the collagen-specific amino acid hydroxyproline is decreased, the fibrosis lesions are decreased, and the degree of lesions is alleviated. Therefore, the Galectin-1 inhibitor can be used as a new treatment strategy for pulmonary fibrosis.

Abstract: A method and systems for taking downhole measurements. The method may include selecting a pulsing scheme for taking one or more measurements using a pulsed neutron logging tool, selecting a neutron burst width for the pulsing scheme based at least in part on a neutron tube utilized by the pulsed neutron logging tool to form at least in part a neutron burst train, and selecting a decay window in which the one or more measurements are performed by the pulsed neutron logging tool. The method may further include selecting a starting time for a late gate in which the one or measurements are taken, disposing the pulsed neutron logging tool into a borehole, performing the neutron burst train with the pulsed neutron logging tool, and performing the one or more measurements with the pulsed neutron logging tool during the late gate.

Abstract: Embodiments of the disclosure provide an image processing method and apparatus, an electronic device and a storage medium. The method includes: when it is detected that a main body to be processed on a display interface is a target main body, adding an augmented reality (AR) special effect model for the target main body; according to a current video frame and a previous historical video frame, determining a target display location of the AR special effect model in the current video frame; displaying the AR special effect model at the target display position to obtain a target special effect video frame corresponding to the current video frame.

Abstract: Embodiments of the present disclosure provide a method and apparatus for determining effect video, an electronic device, and a storage medium. The method includes: in response to detecting that a target effect template is triggered, retrieving a target configuration file; determining the target edit item corresponding to the target effect template and the edit parameter of the target edit item by parsing the target configuration file, and displaying the target edit item; in response to receiving an effect material to be edited corresponding to a target edit item, displaying an edit parameter, so as to determine a target effect material corresponding to the effect material to be edited based on an adjustment operation on the edit parameter; and based on the target effect material and a video stream to be processed, generating a target effect video with the video stream to be processed as background information.

Abstract: Provided is use of pirfenidone (PFD) combined with nintedanib (BIBF 1120) in preparation of a drug for treating pneumoconiosis, which relates to the technical field of biomedicine. In the present disclosure, silicosis model mice in a fibrosis stage are used as a subject to allow research. A combined drug of PFD and BIBF 1120 to silicosis mice may effectively alleviate the progression of silicosis. The combined drug shows superiority in lung function, inflammation, and fibrosis, and exhibits an effect better than therapy with PFD or BIBF 1120 alone. Meanwhile, after the combined administration of PFD and BIBF 1120, there is no significant change in a body weight of the mice, and there is also no significant increase in liver function injury indicators such as serum aminotransferase, alanine aminotransferase (ALT), and aspartate aminotransferase (AST).

Abstract: Disclosed are a range hood and a vehicle. The range hood includes a box, a fan, and a first baffle ring. The box is provided with an accommodation cavity, and an air inlet and an air outlet communicating with the accommodation cavity. The fan is at least partially housed in the accommodation cavity, and includes an impeller and a motor which is connected to and configured to drive the impeller. In the axial direction of the impeller, projection of the impeller is within projection of the air inlet. There is a gap between the projection of the impeller and the projection of the air inlet. A projection of the first baffle ring covers the gap in the axial direction of the impeller.

Abstract: An information display method, an apparatus, an electronic device, a storage medium, and a program product are provided. The information display method includes: playing a first content on a media content playing interface; and switching the first content to a second content in response to a content switching operation by a first user based on a media content stream in the media content playing interface, wherein the second content is associated information of a target object, the associated information comprises description information of the target object, and at least part of the associated information is displayed in a form of dynamic comment information.

Abstract: A interface display method. The method comprises: receiving a trigger operation which acts on a preset control, wherein the preset control is displayed in a playing interface of a target video, and the playing interface is used for playing a target picture at an initial position; in response to the trigger operation, acquiring a target area associated with the preset control; and displaying a fusion interface of the target area and the target picture of the target video, wherein the target picture is kept in a playing state.

Abstract: Provided is a method for preparing copper azide and cuprous azide encapsulated by conductive metal-organic framework. The method uses a conductive copper-containing metal-organic framework material as a precursor, and completes the azidation of the precursor by means of a liquid-solid electrochemical azidation reaction. Copper azide and cuprous azide nanocrystals are highly uniformly embedded within a conductive framework, which may effectively avoid the agglomeration of copper azide and cuprous azide, and reduce static charge generated by friction, displacement, and the like. Meanwhile, the conductive framework may promote the effective transfer of charge, avoid the accumulation of static charge, and improve the electrostatic safety.

Abstract: A bottom rail buffer rebound synchronization device, including rebound components, and a synchronous linkage assembly provided between the rebound components. The rebound components include a fixed plate assembly, a toggle block assembly slidably provided on the fixed plate assembly, an elastic sliding assembly, and a synchronous sliding assembly. The elastic sliding assembly is provided with an elastic stopper that can be extended and retracted. The fixed plate assembly is provided with an orienteering protrusion, which forms a backward guide groove, a separation guide groove, a clamping groove position, a forward guide groove, and a reset guide groove with the fixed plate assembly. The elastic sliding assembly is slid in the backward guide groove, the separation guide groove, the clamping groove position, the forward guide groove, and the reset guide groove in a cycle manner.

Abstract: A video editing method is provided. A clip identifier in one-to-one correspondence with a video clip indicated by a video editing template is displayed based on the video editing template, to prompt a user to import a video material for a specified video clip corresponding to the clip identifier; in response to a trigger operation of presenting an editing result, the editing result, which is obtained by applying, on a target video material, a specified editing operation indicated by the video editing template, is presented, wherein the target video material corresponds to the specified video clip; the target video material is used to be imported into the corresponding specified video clip to form the editing result; and if the specified video clip includes a first video clip into which the user does not import a video material, a preset video material is added into the first video clip.

Abstract: The disclosure discloses a method and an apparatus for stylizing a three-dimensional model, an electronic device, and a storage medium. The method for stylizing the three-dimensional model includes: acquiring a to-be-stylized three-dimensional model and a stylized target image; and rendering the three-dimensional model by using a predetermined network to acquire a two-dimensional rendered image and spatial feature parameters of a pixel, and stylizing a texture feature in the two-dimensional rendered image based on the spatial feature parameters and the stylized target image to acquire a stylized three-dimensional model.

Abstract: A method for producing light aromatic hydrocarbons from C9+ aromatic hydrocarbons includes a step of contacting a C9+ aromatic hydrocarbon with a dealkylation catalyst comprising a KL zeolite, and platinum and a modifying metal supported thereon in the presence of hydrogen, to obtain a light aromatic hydrocarbon. The modifying metal is selected from the group consisting of Group IIA metals and rare earth metals. By using a Pt/KL catalyst comprising a specific modifying metal in the dealkylation reaction of C9+ aromatic hydrocarbons for producing light aromatic hydrocarbons, the method shows the advantages of high conversion rate of feedstock, high yield of light aromatic hydrocarbons, good reaction selectivity.

Abstract: The present application relates to a circuit, a method, and a radar for detecting ambient light. The circuit comprises: a photosensitive element, which is configured to convert a received light signal into a current signal; an electrical signal conditioning circuit, coupled to the photosensitive element, which is configured to convert the current signal into a voltage signal; a demodulation processing unit, coupled to the electrical signal conditioning circuit, which is configured to convert the voltage signal into a digital signal based on a voltage threshold; and a digital processing unit, coupled to the demodulation processing unit, which is configured to process the digital signal to obtain ambient light information.

Abstract: The present application relates to a video collection presentation method and apparatus, an electronic device, and a readable storage medium. The method comprises: presenting a plurality of first videos explaining video clipping skills in a video collection in a second page in the form of a directory, wherein when the video collection is presented by means of a directory, a subdirectory corresponding to the first videos comprises a plurality of directory items at different levels.

Abstract: An urban underground space resistivity sensing system and data collection method based on cloud-edge-end collaboration is disclosed. Employing an advanced cloud-edge-end architecture design, data collection tasks are decentralized to distributed edge nodes and sensing nodes. Computational tasks intensive in data processing and data mining are deployed on a central cloud computing platform, ensuring real-time and efficient data collection. Simultaneously, a three-dimensional spatial arbitrarily distributed sensing network is jointly constructed with well structures in the ground. Leveraging favorable conditions such as embedded horizontal cables and longitudinally drilled holes on both sides of roads, the system flexibly deploys a three-dimensional resistivity sensing network traversing streets, addressing the limitations of singular surface exploration and achieving detailed imaging of subterranean targets beneath urban streets.

Abstract: A video editing method is provided. A clip identifier in one-to-one correspondence with a video clip indicated by a video editing template is displayed based on the video editing template, to prompt a user to import a video material for a specified video clip corresponding to the clip identifier; in response to a trigger operation of presenting an editing result, the editing result, which is obtained by applying, on a target video material, a specified editing operation indicated by the video editing template, is presented, wherein the target video material corresponds to the specified video clip; the target video material is used to be imported into the corresponding specified video clip to form the editing result; and if the specified video clip includes a first video clip into which the user does not import a video material, a preset video material is added into the first video clip.

Abstract: This application discloses a LiDAR controlling method, the LiDAR includes a laser emission array and a laser receiving array, and the method includes: in a measurement cycle, determining at least one emission block to be turned on in a current measurement cycle from the laser emission array, where the laser emission array includes multiple emission blocks, and each emission block includes multiple emission units; controlling at least one emission block to emit a laser beam according to a preset rule; and controlling a receiving block in the laser receiving array that corresponds to the at least one emission block to receive a laser echo, where the laser echo refers to an echo formed after the laser beam is reflected by a target object.

Abstract: A low-cost modular liquid nitrogen low-temperature multi-nuclear magnetic resonance probe includes a Dewar, a pluggable coil and a front-end gain amplifier. The Dewar includes a cylindrical sandwich chamber, the center of the cylindrical sandwich chamber constitutes a room-temperature chamber, a sandwich of the cylindrical sandwich chamber is divided into a vacuum chamber and a liquid nitrogen chamber by a liquid nitrogen vessel wall, the vacuum chamber is located between the room-temperature chamber and the liquid nitrogen chamber, the pluggable coil and the front-end gain amplifier are provided in the vacuum chamber, the pluggable coil comprises a coil portion and a pluggable base, the coil portion is in pluggable connection with the pluggable base, and the pluggable coil is connected with the front-end gain amplifier. The probe realizes the transmission of radio frequency pulses and the reception of magnetic resonance signals, and is applicable to whole-body imaging of a small animal.