Abstract: Some embodiments of the teachings herein include a motion control method. An example includes: creating a motion control model; training an online reinforcement learning model using the model; producing feedback with a controlled object, a model control value, and an initial control value; calculating a reward using the control value and the feedback; generating a residual control value using the online reinforcement learning model based on the reward, the model control value, and the feedback; controlling motion of the object with the residual control value and the model control value; sending the motion control model, the model control value, the feedback, and the reward to the cloud; training an offline model with the motion control model, the model control value, the feedback value, and the reward; and updating the existing online model using the offline model or deploying the offline model in a motion control system without an online model.

Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: A charging circuit is provided. The charging circuit includes a protection circuit and a charging control switch connected in series, and a transfer switch. The transfer switch is configured to switch to a first charging circuit by connecting to the protection circuit, and switch to a second charging circuit by connecting to the charging control switch. A maximum charging voltage of the first charging circuit is lower than a maximum charging voltage of the second charging circuit.

Abstract: The present disclosure provides a smokeless cooking appliance, including a cooking assembly. A fan flue is mounted above the cooking assembly in a crossing manner. A lower surface of the fan flue is provided with smoke inlets right above the cooking assembly. Smoke extraction devices are mounted in the smoke inlets. Two air guide pipe fittings are disposed below the cooking assembly. Air inlets of the two air guide pipe fittings are respectively in communication with two lower ports of the fan flue. Air outlets of the two air guide pipe fittings are respectively disposed on two sides of an upper surface of the cooking assembly.

Abstract: The present disclosure relates to a compound of Formula (I), a tautomer, a stereoisomer or a mixture of stereoisomers, a pharmaceutically acceptable salt, a hydrate, or a deuterated derivative thereof and their use in, e.g., treating a disease or disorder associated with CDK2. The present disclosure also relates to pharmaceutical compositions containing such compounds, and their use in treating or preventing a disease or disorder associated with CDK2.

Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: A light-emitting device is provided. The light-emitting device generates a white light and includes at least one light-emitting diode. The at least one light-emitting diode generates a light beam with a broadband blue spectrum and includes a first semiconductor layer, a second semiconductor layer and a multiple quantum well structure. The multiple quantum well structure is located between the first semiconductor layer and the second semiconductor layer, and includes well layers and barrier layers. The well layers include a first well layer, a second well layer and third well layers different in indium concentrations. The first well layer has the largest indium concentration, and the third well layers have the smallest indium concentration. Three of the well layers that are closest to the first semiconductor layer are the third well layers, and the first well layer is closer to the second semiconductor layer than the first semiconductor layer.

Abstract: An example system includes: a production system skill library, with a plurality of skill blocks describing and encapsulating the realization part of the skills involved in the production process; a unified execution engine with a plurality of skill function blocks describing and encapsulating the interface part of the skills involved in the production process; to receive a production procedure programmed by a user based on the skill function blocks, and successively start each skill function block in the production procedure to call at least one corresponding skill block; and device agents for controlling devices in the production system. Each device agent is used to provide a unified interface to control the corresponding device to perform operations according to the operation instructions from the unified execution engine or the skill block.

Abstract: A detection device includes a substrate and a die. The substrate provides a first voltage. The die is disposed adjacent to the substrate. The die includes a plurality of resistor paths, a selection circuit, an ADC (Analog-to-Digital Converter), and a digital circuit. The selection circuit selects one of the resistor paths as a target path. The target path provides a second voltage. The ADC generates a digital signal according to the first voltage and the second voltage. The digital circuit processes the digital signal.

Abstract: The present disclosure provides a method of preparing olefins from methanol, in which methanol and phenol-like molecules are used as raw material, which is gasified and then passed into a two-stage fixed-bed catalytic reactor. The raw material reacts with a catalyst A (silica-aluminum molecular sieve) and a catalyst B (silica-aluminum or phosphorus-aluminum molecular sieve) in sequence to produce ethylene.

Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: The present disclosure relates to novel glutarimide-containing compounds with KRAS mutant form degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of diseases and conditions.

Abstract: The present disclosure relates to novel SOS1 inhibitors, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.

Abstract: The present disclosure relates to novel quinolinone-8-carbonitrile based compounds, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions. The compounds disclosed herein exhibit androgen receptor degradation activity.

Abstract: The invention proposes a kind of bending bolt type anti-loosening nut, which relates to the technical field of mechanical fastening. It comprises an upper nut and a lower nut, the upper nut and the lower nut are stacked on the outside of the bolt and used to tightly connect the bolt to the connecting piece, the lower nut is arranged close to the connecting piece, the upper nut is arranged on the outer end surface of the lower nut; the adjacent end between the upper nut and lower nut is provided with an inclined surface, the inclined surface is inclined towards the interior of the upper nut, so that an inclined plane angle with deformation space between the upper nut and lower nut is formed; the invention achieves the effect of preventing nut loosening, is low in price, easy to manufacture, and suitable for small or miniature anti-loosening nuts.

Abstract: Various embodiments of the teachings herein include a method for knowledge recommendation. The method may include: obtaining current searching information of a user for certain knowledge in factory production, job characteristic information of the user, and historical feedback information of the user for at least one knowledge item and/or knowledge resource in the past; using a first prediction algorithm model for learning based on historical searching information, job feature information, and historical feedback information of the user and other users to analyze obtained information, to obtain first prediction information including a first number of knowledge items; using a second prediction algorithm model to perform fusion sorting on the first prediction information and thereby obtain second prediction information including a second number of knowledge items; providing the second number of knowledge items to a knowledge recommendation model; and recommending a knowledge resource output from the model.

Abstract: The present disclosure relates to a method, device, and system for configuring parameters, a computer device, a medium, and a product. A configuration device for configuring parameter sampling with respect to an edge device includes: one information acquiring unit, configured to acquire information related to the purpose and use environment of the edge device; one transmitting unit, configured to transmit the information to a cloud platform; and one configuration information determining unit, configured to receive configuration information for parameter sampling with respect to the edge device from the cloud platform, where the configuration information is configuration information determined as matching the information by the cloud platform utilizing a configuration model stored thereby.

Abstract: A method for specifying an object, includes: determining whether a pointing device is in a pointing mode or a control mode; determining a first position of a first locator and a second position of a second locator in the pointing device in a virtual space, when the pointing device is in the pointing mode; determining a pointing of the pointing device based on the first position of the first locator and the second position of the second locator; and determining a specified virtual object based on the pointing of the pointing device.

Abstract: The present disclosure relates to novel compounds that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK.

Abstract: The present disclosure relates to novel compounds that inhibit glucose-induced degradation-deficient (GID) E3 ligase, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.