Abstract: The present invention discloses a hydrogel that can be degraded under physiological conditions. The hydrogel includes at least one backbone moiety and an optional crosslinking moiety, and biodegradable linkers connecting backbone moieties and crosslinking moieties can be degraded by intramolecular cyclization.

Abstract: A probe system and a method are provided. The probe system includes an emitter unit, a pattern generation system, and an intensity modulator. The emitter unit is for emitting light. The pattern generation system is for projecting at least one reference structured-light pattern onto an object surface to obtain at least one reference projected pattern, and including a mirror scanning unit for reflecting the light to a plurality of directions. The intensity modulator is for modulating intensity of the light according to the at least one reference projected pattern to provide modulated light to the mirror scanning unit to reflect the modulated light to the plurality of directions to project at least one modulated structured-light pattern onto the object surface to obtain at least one modulated projected pattern.

Abstract: Embodiments include a method and apparatus for evaluating code in hierarchical architecture software, and a storage medium. The method includes acquiring layer definition information, of hierarchical architecture software to be tested, including layer information and intra-layer component information; scanning code of the hierarchical architecture software to be tested, to acquire basic information of the code including component information, intra-component file information and intra-file code metric information; mapping the basic information with the layer definition information, to obtain file information of each component in each layer of the hierarchical architecture software to be tested and intra-file code metric information; and calculating a code evaluation parameter of the hierarchical architecture software to be tested, based upon the file information of each component in each layer and the intra-file code metric information.

Abstract: Disclosed are promoieties of the following formula which can be used to form prodrugs of nitrogen-containing or hydroxyl-containing drug or a pharmaceutically active agent: and pharmaceutical compositions comprising the prodrugs.

Abstract: The present invention discloses a hydrogel that can be degraded under physiological conditions. The hydrogel includes at least one backbone moiety and an optional crosslinking moiety, and biodegradable linkers connecting backbone moieties and crosslinking moieties can be degraded by intramolecular cyclization.

Abstract: Disclosed herein are insulin agonist peptides conjugated to a glucagon analog wherein the insulin/glucagon conjugate is targeted to liver tissues upon administration to a patient.

Abstract: Generating granular clusters for real-time processing is provided. The systems can identify tokens based on aggregating input from computing devices over a time interval. The systems can identify, based on metrics, a subset of tokens for cluster generation. The systems can generate, via a clustering technique, token clusters from the subset of the tokens, each of the token clusters comprising two or more tokens from the subset of the tokens. The systems can apply a de-duplication technique to each of the token clusters. The systems can apply a filtering technique to the token clusters to remove tokens erroneously grouped in a token cluster. The systems can assign, based on a selection process, a label for each of the token clusters. The systems can activate, based on a number of remaining tokens in each of the token clusters, a subset of the token clusters for real-time content selection.

Abstract: Disclosed are promoieties of the following formula which can be used to form prodrugs of nitrogen-containing or hydroxyl-containing drug or a pharmaceutically active agent: and pharmaceutical compositions comprising the prodrugs.

Abstract: Embodiments include a method and apparatus for evaluating code in hierarchical architecture software, and a storage medium. The method includes acquiring layer definition information, of hierarchical architecture software to be tested, including layer information and intra-layer component information; scanning code of the hierarchical architecture software to be tested, to acquire basic information of the code including component information, intra-component file information and intra-file code metric information; mapping the basic information with the layer definition information, to obtain file information of each component in each layer of the hierarchical architecture software to be tested and intra-file code metric information; and calculating a code evaluation parameter of the hierarchical architecture software to be tested, based upon the file information of each component in each layer and the intra-file code metric information.

Abstract: Provided is a method and a device for forwarding a packet. The method includes: receiving, by a first node, a packet to be forwarded, where a destination address of the packet is a second node; searching, by the first node, a plurality of pre-generated paths for a target path corresponding to the packet, where the plurality of pre-generated paths include a first path, a second path and a third path; searching, by the first node, a plurality of pre-generated segment lists for a target segment list corresponding to the target path when the target path is one of the first path or the second path; and searching, by the first node, the target path for a next hop node for forwarding to the second node and forwarding the packet to the next hop node according to the target segment list.

Abstract: A method and device for measuring a substance's concentration in a fluid. The method includes first passing a sample to be measured through a chemical sensor at least twice and recording the response value each time; forming a simultaneous equation set using the equation relation between the response value obtained during each measurement and the concentration of the substance, and the mass equation relation satisfied by the concentration change caused by a physical, chemical reaction during each measurement and by the change of the mass, electric quantity, and heat; solving for the concentration of the substance measured and the sensor calibration parameter. The method, used as an absolute measurement method, can be applied to calibrate the sample concentration of a fluid, overcomes the effects on the measurements caused by temperature, humidity, pressure, and some interfering gas, requires no sensor calibration, and substantially enhances the measurements' stability and reliability.

Abstract: Disclosed herein are insulin agonist peptides conjugated to a glucagon analog wherein the insulin/glucagon conjugate is targeted to liver tissues upon administration to a patient.

Abstract: A method and device for measuring a substance's concentration in a fluid. The method includes first passing a sample to be measured through a chemical sensor at least twice and recording the response value each time; forming a simultaneous equation set using the equation relation between the response value obtained during each measurement and the concentration of the substance, and the mass equation relation satisfied by the concentration change caused by a physical, chemical reaction during each measurement and by the change of the mass, electric quantity, and heat; solving for the concentration of the substance measured and the sensor calibration parameter. The method, used as an absolute measurement method, can be applied to calibrate the sample concentration of a fluid, overcomes the effects on the measurements caused by temperature, humidity, pressure, and some interfering gas, requires no sensor calibration, and substantially enhances the measurements' stability and reliability.

Abstract: A probe system and a method are provided. The probe system includes an emitter unit, a pattern generation system, and an intensity modulator. The emitter unit is for emitting light. The pattern generation system is for projecting at least one reference structured-light pattern onto an object surface to obtain at least one reference projected pattern, and including a mirror scanning unit for reflecting the light to a plurality of directions. The intensity modulator is for modulating intensity of the light according to the at least one reference projected pattern to provide modulated light to the mirror scanning unit to reflect the modulated light to the plurality of directions to project at least one modulated structured-light pattern onto the object surface to obtain at least one modulated projected pattern.

Abstract: A device for replacing sanding elements of a polishing device includes a first support, a second support, a feeder assembly, a suction assembly, a first pushing assembly, a second pushing assembly, and a clamping assembly. The feeder assembly includes a receiving member configured to receive the sanding elements, and a supporting member positioned below the receiving member. The suction assembly includes a suction member configured to draw a sanding element from the receiving member, and a rotary actuator configured to rotate the suction member. The first pushing assembly is configured to receive the sanding element from the suction member and transport the sanding element to the polishing device. The clamping assembly is configured to attach an unused sanding element to, and detach a used sanding element from, a manipulator of the polishing device, and the second pushing assembly is configured to separate the sanding element from the clamping assembly.

Abstract: A device for replacing sanding elements of a polishing device includes a first support, a second support, a feeder assembly, a suction assembly, a first pushing assembly, a second pushing assembly, and a clamping assembly. The feeder assembly includes a receiving member configured to receive the sanding elements, and a supporting member positioned below the receiving member. The suction assembly includes a suction member configured to draw a sanding element from the receiving member, and a rotary actuator configured to rotate the suction member. The first pushing assembly is configured to receive the sanding element from the suction member and transport the sanding element to the polishing device. The clamping assembly is configured to attach an unused sanding element to, and detach a used sanding element from, a manipulator of the polishing device, and the second pushing assembly is configured to separate the sanding element from the clamping assembly.

Abstract: A non-isolated light-emitting diode (LED) driving circuit has a rectifier, a switching device, a sampling resistor, a power supply unit, a controller unit and a lighting unit. The controller unit samples a voltage at the sampling resistor to compare the sampling voltage with reference voltage to determine if the switching device is turned on or off. When the switching device is turned on, a charging current outputted from the rectifier charges the power supply unit and the power supply unit simultaneously discharges to supply power to the lighting unit. When the switching device is turned off, a discharging current outputted from the power supply unit supplies power to the lighting unit. As there are no transformer and electrolytic capacitor, the non-isolated LED driving circuit is simplified, durable and cost-effective.

Abstract: Disclosed herein are insulin agonist peptides conjugated to incretins wherein the insulin/incretin conjugate has agonist activity at both the insulin receptor and the corresponding incretin receptor. Insulin is a proven therapy for the treatment of juvenile-onset diabetes and later-stage adult-onset diabetes. The peptide is biosynthesized as a larger linear precursor of low potency (approximately 2% to 9% of native insulin), named proinsulin. Proinsulin is proteolytically converted to insulin by the selective removal of a 35-residue connecting peptide (C peptide).

Abstract: An optical system configured to visually inspect a target having a variable position with respect to the optical system is provided. The optical system includes a polarizer configured to convert an incident light reflected or diffused from the target into linearly polarized light; a light modulating element configured to modulate a polarization state of the linearly polarized light in response to control signals; and a lens group comprising at least one birefringent element, the birefringent element configured to refract or reflect the modulated linearly polarized light with a first polarization state under a first refraction index to enable inspection of the target at a first object position, and the birefringent element further configured to refract or reflect the modulated linearly polarized light with a second polarization state under a second refraction index to enable inspection of the target at a second object position.

Abstract: The borescope includes an insertion tube, a first image processor, a model store unit, a pose calculator, a second image processor, a navigation image calculator and a display. The insertion tube includes a detection head and at least one sensor for receiving signals in the insertion tube and generating sensed signals. The first image processor is for calculating a first image based on first image signals captured by the detection head. The second image processor is for adjusting the initial pose calculated by the pose calculator to a navigation pose until a difference between the first image and a second image calculated based on the navigation pose and a predetermined model falls in an allowable range. The navigation image calculator is for calculating a navigation image based on the navigation pose and the predetermined model. The display is for showing the navigation image.