Patents by Inventor Jie Wen

Jie Wen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140199468
    Abstract: A nanofiber is formed by combining one or more natural or synthetic polymeric materials and one or more than one cross-linking agents having at least two latent reactive activatable groups. The latent reactive activatable nanofiber may be used to modify the surface of a substrate by activating at least one of the latent reactive activatable groups to bond the nanofiber to the surface by the formation of a covalent bond between the surface of the substrate and the latent reactive activatable group. Some of the remaining latent reactive activatable group(s) are left accessible on the surface of the substrate, and may be used for further surface modification of the substrate. Biologically active materials may be immobilized on the nanofiber modified surface by reacting with the latent reactive groups that are accessible on the surface of the substrate.
    Type: Application
    Filed: March 10, 2014
    Publication date: July 17, 2014
    Applicant: Innovative Surface Technologies, Inc.
    Inventors: Jie Wen, Patrick E. Guire
  • Patent number: 8779206
    Abstract: The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous environments.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: July 15, 2014
    Assignee: Innovative Surface Technologies, LLC
    Inventors: Patrick E. Guire, Kristin Taton, Jie Wen
  • Patent number: 8709809
    Abstract: A nanofiber is formed by combining one or more natural or synthetic polymeric materials and one or more than one cross-linking agents having at least two latent reactive activatable groups. The latent reactive activatable nanofiber may be used to modify the surface of a substrate by activating at least one of the latent reactive activatable groups to bond the nanofiber to the surface by the formation of a covalent bond between the surface of the substrate and the latent reactive activatable group. Some of the remaining latent reactive activatable group(s) are left accessible on the surface of the substrate, and may be used for further surface modification of the substrate. Biologically active materials may be immobilized on the nanofiber modified surface by reacting with the latent reactive groups that are accessible on the surface of the substrate.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: April 29, 2014
    Assignee: Innovative Surface Technologies, Inc.
    Inventors: Jie Wen, Patrick E. Guire
  • Patent number: 8691983
    Abstract: The invention provides compositions that include crosslinking agents having multiple photoactivatable groups, such as diaryl ketones, or a diaryl ketone, such as benzophenone, and at least one polymerizable monomer, such as a zwitterionic monomer. The compositions are useful as surface coating agents that provide brush type polymeric coatings. These polymeric coatings can be used on medical devices, such as artificial joints, to reduce wear and tear between the components of the joint and thus reduce or eliminate debris generated by friction between the joint components.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: April 8, 2014
    Assignee: Innovative Surface Technologies, Inc.
    Inventors: Jie Wen, Laurie R. Lawin, Patrick Guire
  • Patent number: 8663674
    Abstract: Polymeric matrices including microparticles that provide sustained release of a hydrophilic bioactive agent are described. The matrices can be in the form of a coating on the surface of an implantable medical article or an in situ formed matrix. The microparticles of the matrix include a first polymer and a second polymer that modulates release of the hydrophilic bioactive agent from the matrix.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: March 4, 2014
    Assignee: Surmodics, Inc.
    Inventors: Jie Wen, Aron B. Anderson
  • Publication number: 20140021814
    Abstract: A method for interconnecting electronic power modules of a polyphase rotary electric machine. The power modules are disposed in open cavities of a heat sink and comprise substrates on which are provided MOSFETs of a synchronous rectifier bridge and integrated control circuits. The method comprises the production of: a planar connector (6) including at least one layer of conductive traces (64); a plurality of interconnection elements (512) arranged in multiple geometric formations and ultrasonically welded or brazed (S2) directly to the substrates (51) and/or the MOSFETs; and openings (65) in the planar connector (6) allowing the free passage of the upper ends (5120) of the connection elements (512) and a mechanical contact with the conductive traces (64). The electrical connections are obtained by means of laser (8) transmission welding (S1) or electric resistance welding.
    Type: Application
    Filed: November 17, 2011
    Publication date: January 23, 2014
    Applicant: VALEO EQUIPEMENTS ELECTRIQUES MOTEUR
    Inventors: Regis Seidenbinder, Bryann Lafabrie, Fbrice Tauvron, Cyrille Dheripre, David Delplace, Marc Tunzini, Romaric Guillard, Ruth Lopeze, Jie Wen
  • Publication number: 20140011938
    Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.
    Type: Application
    Filed: July 29, 2013
    Publication date: January 9, 2014
    Applicant: INNOVATIVE SURFACE TECHNOLOGIES, INC.
    Inventors: Patrick E. Guire, Kristin Taton, Jie Wen, Laurie R. Lawin
  • Publication number: 20140009016
    Abstract: An architecture of interconnected electronic power modules for a polyphase rotary machine, comprising electrically interconnected power modules (5) and a connector (6) including one or more layers formed by pluralities of conductive traces borne by plates, such as to connect the power modules (51 to 53) to one another and to electrical elements of the rotary machine. The power modules (51 to 53) comprise a plurality of connection elements (510 to 530) brazed directly to components of the power modules (51 to 53) and, in the upper part, to conductive traces of the connector (6). This architecture includes a heat sink (4) equipped with open cavities (41 to 43) for receiving the power modules (51 to 53). A polyphase rotary machine is also provided using such an architecture, in particular a dual three-phase alternator with synchronous rectification.
    Type: Application
    Filed: November 17, 2011
    Publication date: January 9, 2014
    Applicant: VALEO EQUIPEMENTS ELECTRIQUES MOTEUR
    Inventors: Regis Seidenbinder, Bryann Lafabrie, Fabrice Tauvron, Cyrille Dheripre, David Delplace, Mar Tunzini, Romaric Guillard, Ruth Lopez, Jie Wen
  • Publication number: 20130317086
    Abstract: The invention is directed to transfection reagents for the delivery of nucleic acids into neural cells, compositions including the reagents, methods of preparation of such reagents, methods of transfecting cells with such reagents, and uses thereof. In preferred embodiments the reagents comprise horseradish peroxidase and/or a polycarboxylic acid such as poly(acrylic acid) or poly(methacrylic acid).
    Type: Application
    Filed: February 7, 2012
    Publication date: November 28, 2013
    Inventors: Eric Guire, Jie Wen
  • Publication number: 20130303759
    Abstract: The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous environments.
    Type: Application
    Filed: July 15, 2013
    Publication date: November 14, 2013
    Inventors: Patrick E. Guire, Kristin Taton, Jie Wen
  • Patent number: 8496857
    Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: July 30, 2013
    Assignee: Innovative Surface Technologies, Inc.
    Inventors: Patrick E. Guire, Kristin Taton, Jie Wen, Laurie R. Lawin
  • Patent number: 8487137
    Abstract: The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous environments.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: July 16, 2013
    Assignee: Innovative Surface Technologies, LLC
    Inventors: Patrick E. Guire, Kristin Taton, Jie Wen
  • Publication number: 20130171331
    Abstract: A stimuli responsive nanofiber that includes a stimuli responsive polymer, such as a thermally responsive polymer, and a cross-linking agent having at least two latent reactive activatable groups. The nanofiber may also include a biologically active material or a functional polymer. The stimuli responsive nanofiber can be used to modify the surface of a substrate. When the nanofiber includes a thermally responsive polymer, the physical properties of the surface can be controlled by controlling the temperature of the system, thus controlling the ability of the surface to bind to a biologically active material of interest.
    Type: Application
    Filed: December 10, 2012
    Publication date: July 4, 2013
    Inventors: Tahmina Naqvi, Jie Wen, Patrick Guire
  • Publication number: 20130052899
    Abstract: A resin-and-fiber includes a base layer and a molded layer integrally bonding the base layer. The base layer includes a fiber layer made of fiber woven fabric and a resin layer made of transparent or translucent resin. The fiber layer has a first surface and an opposite second surface. The resin layer bonds the first surface and penetrating into the fiber layer. The molded layer is made of resin and integrally bonding the second surface of the fiber layer. A method for making the present resin-and-fiber composite is also provided.
    Type: Application
    Filed: November 23, 2011
    Publication date: February 28, 2013
    Applicants: FIH (HONG KONG) LIMITED, SHENZHEN FUTAIHONG PRECISION INDUSTRY CO., LTD.
    Inventors: WU LI, QIANG ZHANG, XUAN-ZHAN ZENG, DA-QING HUANG, YUAN-LEI ZHANG, ZHI-WEI HU, MING-LIANG WANG, YUN-FENG HUANG, QING XIA, HE-JIE WEN
  • Publication number: 20120258313
    Abstract: The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by application of additional coating layers), or for providing desirable properties to a surface.
    Type: Application
    Filed: December 21, 2010
    Publication date: October 11, 2012
    Inventors: Jie Wen, Kristin Taton, Laurie Lawin, William Knopke, Eric Guire, Patrick Guire
  • Publication number: 20120144244
    Abstract: A method that determines the system impact of single event upset (SEU) and a single event upset (SEU) wrapper that controls a SEU controller is disclosed. The method injects faults into a component (e.g. FPGA, ASIC) of an operational system that is carrying live traffic and monitors the system's response to the faults to determine the impact of SEU on the system. The SEU wrapper sends the SEU controller a pattern scheme that includes information indicating when, where, how often, and/or how long to inject bursts of one or more faults into memory of the component of the system. A burst of faults contains faults that are consecutively injected into the array of memory blocks. After each fault in a burst is injected, one or more errors in one or more memory elements are detected and/or corrected. Information regarding the detection and/or the correction of an error is updated using registers that store counters. After injecting a burst of faults, the SEU controller waits for a predetermined amount of time.
    Type: Application
    Filed: December 7, 2010
    Publication date: June 7, 2012
    Inventors: Yie-Fong Dan, Shi-Jie Wen, Raymond Ng
  • Publication number: 20110268973
    Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.
    Type: Application
    Filed: June 23, 2011
    Publication date: November 3, 2011
    Inventors: Patrick E. Guire, Kristin Taton, Jie Wen, Laurie R. Lawin
  • Publication number: 20110223336
    Abstract: The invention describes novel compositions of crosslinkers that include at least two pendent photoactivatable groups, such as benzophenone moieties, and an initiator, such as acetophenone.
    Type: Application
    Filed: September 3, 2009
    Publication date: September 15, 2011
    Applicant: INNOVATIVE SURFACE TECHNOLOGIES, INC.
    Inventors: Timothy A. Bloomquist, Mark W. Josephson, Laurie R. Lawin, Kristin S. Taton, Jie Wen
  • Publication number: 20110223212
    Abstract: The invention describes nanotextured super hydrophobic coatings that contain active agents which can elute from the coating over a period of time.
    Type: Application
    Filed: September 15, 2009
    Publication date: September 15, 2011
    Inventors: Kristin S. Taton, Patrick E. Guire, Laurie R. Lawin, Jie Wen
  • Patent number: 7989619
    Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: August 2, 2011
    Assignee: Innovative Surface Technoloiges, Inc.
    Inventors: Patrick Guire, Kristin Taton, Jie Wen, Laurie R. Lawin