Abstract: The present invention relates to a method for culturing a 3-dimensional lung cancer organoid and a method for preparing a patient-derived xenograft animal model using the same. More specifically, the present invention relates to a method for culturing a 3-dimensional lung cancer organoid, a lung cancer organoid prepared by the method, a medium composition for culturing the lung cancer organoid, a method for preparing a xenograft animal model using the lung cancer organoid, a patient-derived lung cancer organoid xenograft animal model prepared by the method, and a method for analyzing therapeutic efficacy of an anticancer agent and a method for screening an anticancer agent, using the animal model.

Abstract: An apparatus for processing a substrate includes a processing vessel disposed in a process chamber and including a processing space in which a substrate is accommodated; a liquid supply line configured to process the substrate by supplying processing liquid to the substrate in the processing space; an exhaust line connected to the processing vessel and configured to exhaust gas in the processing space; a spraying portion disposed on the exhaust line and configured to spray cleaning liquid to remove contaminants accumulated in the exhaust line; and a washing liquid discharge line branched from the exhaust line and including a suction portion therein to suction cleaning liquid waste including contaminants removed from the exhaust line by the cleaning liquid and to discharge the cleaning liquid waste to the outside.

Abstract: The present invention relates to a technology for analyzing and detecting/diagnosing a target nucleic acid. When the detection system according to the present invention is used, effective real-time detection or diagnosis efficiency can be obtained while problems such as noise are minimized. In particular, since, by using a house-keeping gene according to a method of use, the expression difference of the target nucleic acid can be corrected, and direct real-time target nucleic acid detection is possible, it can be effectively used for detecting various nucleic acids and diagnosing various diseases thereby.

Abstract: The inventive concept provides a substrate treating apparatus. The substrate treating apparatus includes a batch-type treating bath for treating a substrate in a batch-type manner; a single-type treating chamber for treating the substrate in a single-type manner; and a buffer chamber positioned on a transfer path of the substrate transferred between the batch-type treating bath and the single-type treating chamber, and supplying a liquid for maintaining a wetting state of the substrate.

Abstract: An image processing apparatus is disclosed. The image processing apparatus includes a communicator configured to transmit or receive information to or from an intraoral scanner, a memory storing one or more instructions, and a processor configured to execute the one or more instructions stored in the memory to identify an oral image obtainment mode based on tip information about a tip included in the intraoral scanner, and obtain an oral image based on two-dimensional image data received from the intraoral scanner through the communicator and the identified oral image obtainment mode, wherein the tip information may include at least one of tip fastening direction information and tip size information.

Abstract: The present invention relates to microfluidic fluidic devices, methods and systems as microfluidic kidney on-chips, e.g. human Proximal Tubule-Kidney-Chip, Glomerulus (Kidney)-Chip, Collecting Duct (Kidney)-Chip. Devices, methods and systems are described for drug testing including drug transport and renal clearance. Further, such devices, methods and systems are used for determining drug-drug interactions and their effect upon renal transporter functions. Importantly, they may be used for pre-clinical and clinical drug development for treating kidney diseases and for personalized medicine.

Abstract: The present invention disclosures an oxide semiconductor transistor and a method of fabricating the same. The oxide semiconductor transistor according to an embodiment of the present invention includes a first gate electrode formed on a substrate; a first gate insulating film formed using a solution process on the first gate electrode; a source electrode and a drain electrode separately formed on one surface of the first gate insulating film; an oxide semiconductor film formed using a solution process on the first gate insulating film and the source and drain electrodes; a second gate insulating film formed using a solution process on the oxide semiconductor film; pixel electrodes separately formed on one surface of the second gate insulating film and electrically connected to the source and drain electrodes, respectively; and a second gate electrode formed on the second gate insulating film.

Abstract: The present invention relates to nucleic add molecules with increased gene silencing activity and uses thereof, wherein a double-stranded nucleic acid molecule or radial nucleic acid molecule comprising a chemically modified nudeotide at a specific position may have effectively increased gene silencing activity and in vivo stability for a target gene.

Abstract: The present invention relates to a charging system for personal mobility devices and, more particularly, may comprises: support units provided with slots into which wheels of personal mobility devices are mounted; first charging units which are installed toward the personal mobility devices and generate magnetic fields for wireless charging; and second charging units which are mounted onto the personal mobility devices, and which covert the magnetic fields, received via the first charging units, into electric power to charge the batteries provided in the personal mobility devices.

Abstract: A display device includes a housing including first and second edge areas; a panel assembly between a window and the housing; a first waterproof member corresponding to the first edge area; a second waterproof member corresponding to the second edge area and disconnected from the first waterproof member; and a first sealing member in contact with the first and second waterproof members, the panel assembly, the window and the housing. The panel assembly includes a plurality of members each protruded further than an end of the first waterproof member to respectively define first edges. Each first edge is in contact with the first sealing member, and protruded distances of the first edges from the end of the first waterproof member increase as a cross-sectional distance from the plurality of members to the window decreases to form a stepped shape of the panel assembly at the first edges.

Abstract: Disclosed is a frequency mixer. The frequency mixer includes a first matching circuit that generates a matched local oscillator (LO) signal based on an LO signal, a non-linear circuit that generates a non-linear LO signal based on the matched LO signal, a second matching circuit that generates a matched radio frequency (RF) signal based on an RF signal, a mixing circuit that generates a mixed signal based on a mixing of the non-linear LO signal and the matched RF signal, a third matching circuit that generates an intermediate frequency (IF) signal based on the mixed signal, wherein the non-linear circuit includes a non-linear transistor, a bias transistor, and an internal matching circuit connected in series.

Abstract: Disclosed are a structure of a quantum-dot light emitting device including a charge generation junction layer and a method of fabricating the quantum-dot light emitting device. A quantum-dot light emitting device according to an embodiment of the present invention includes a negative electrode, a first charge generation junction layer including a p-type semiconductor layer and an n-type semiconductor layer, a quantum-dot light emitting layer, a hole transport layer, a second charge generation junction layer including a p-type semiconductor layer and an n-type semiconductor layer, and a positive electrode. The first and second charge generation junction layers is formed using a solution process. Accordingly, charge generation and injection can be stabilized, a process time can be shorted, and problems in the work function a positive or a negative electrode of a quantum-dot light emitting device can be addressed.

Abstract: A method for outputting a drawing reference number description regarding a patent drawing reference number according to an embodiment of the present disclosure may include recognizing a size of a patent drawing and a position of a drawing reference number included in the patent drawing and acquiring a relative position coordinate of the drawing reference number in the patent drawing; setting a relative position coordinate of the drawing reference number description corresponding to the drawing reference number based on the acquired relative position coordinate; and outputting the drawing reference number description on the set relative position coordinate, thereby outputting such that the drawing reference number description corresponds to the drawing reference number.

Abstract: A method of manufacturing a pouch type battery cell according to an embodiment of the present disclosure includes forming an embossing part in a part of a pouch film by using an embossing punch part. A pouch forming apparatus for forming a receiving part of the pouch film includes an embossing punch part, a die part serving as a passage through which the punch part moves, and a blank holder in contact with the embossing punch part in the die part.

Abstract: Compositions, devices and methods are described for improving adhesion, attachment, and/or differentiation of cells in a microfluidic device or chip. In one embodiment, one or more ECM proteins are covalently coupled to the surface of a microchannel of a microfluidic device. The microfluidic devices can be stored or used immediately for culture and/or support of living cells such as mammalian cells, and/or for simulating a function of a tissue, e.g., a liver tissue, muscle tissue, etc. Extended adhesion and viability with sustained function over time is observed.

Abstract: An apparatus and method for predicting a friction coefficient of a road surface are disclosed. The apparatus includes a microphone that obtains a sound signal around a tire mounted on a vehicle, and a controller that estimates a state and a type of the road surface and a degree of tire wear corresponding to the sound signal around the tire based on a first deep learning model, estimates a peak adjustment factor and an initial inclination adjustment factor of a friction coefficient curve corresponding to the state and the type of the road surface and the degree of tire wear based on a second deep learning model, and predicts the friction coefficient based on the peak adjustment factor and the initial inclination adjustment factor of the friction coefficient curve.

Abstract: A thin film transistor manufacturing method according to an embodiment includes: forming a gate electrode on a substrate; forming a gate insulation layer on the gate electrode; forming a semiconductor layer on the gate insulation layer; and forming a source electrode and a drain electrode that contact the semiconductor layer, wherein the forming of the gate insulation layer and the forming of the semiconductor layer include spray coating on the substrate.

Abstract: The present disclosure provides a spray coater including a spray nozzle unit having at least one spray nozzle and configured to spray a coating material, a spray nozzle transfer unit configured to control a position of the spray nozzle unit by operating a transfer block, on which the spray nozzle unit is mounted, at least in a planar direction, a substrate seating unit positioned below the spray nozzle unit and configured such that a substrate, which is subjected to coating, is seated thereon, a substrate carrier configured to accommodate the substrate before the substrate is coated and accommodate the substrate after the substrate is coated, and a robot arm configured to unload the substrate from the substrate carrier and provide the substrate to the substrate seating unit before the substrate is coated or unload the substrate from the substrate seating unit and load the substrate on the substrate carrier after the substrate is coated.

Abstract: A cooking appliance includes a cavity and a partition configured to partition the cavity. The partition includes an upper partition, a lower partition, and a heater arranged between the upper partition and the lower partition. The partition further includes a heater installation member provided to detachably mount the heater. At least one of the upper partition and the lower partition further includes a heater installation member installation hole to install the heater.

Abstract: The present disclosure provides a reagent composition for detecting illicit drugs, the composition comprising: a diacetylene derivative compound represented by chemical formula 1; and at least one compound selected from among gabazine (SR-95531), an amine group-linked diacetylene derivative represented by chemical formula 2-1, and a gabazine-linked diacetylene derivative represented by chemical formula 2-2.