Abstract: The present invention relates to a composition comprising metformin as an active ingredient for preventing or treating inflammatory bowel disease. The metformin compound or the metformin-etanercept (product name: Enbrel) composite according to the present invention may have excellent effects of maintaining the thickness of the small intestine and length of the large intestine normal, inhibiting or decreasing the activity of IL-17 and TNF-a, and promoting or increasing the activity of IFNr, and therefore can be effectively used as a pharmaceutical composition for preventing or treating autoimmune diseases including inflammatory bowel disease.

Abstract: A manufacturing method of a wire including: forming a lower layer on a substrate; forming a middle layer on the lower layer; forming an upper layer on the middle layer; forming, exposing, and developing a photoresist layer on the upper layer to form a photoresist pattern; and etching the upper layer, the middle layer, and the lower layer by using the photoresist pattern as a mask to form a wire such that the upper layer covers an end of the middle layer.

Abstract: A neural probe array includes a probe body that is implanted into a subject, a fixture body to support a rear end of the probe body, a cladding extending in a lengthwise direction of the probe body in an upper part of the probe body, and an optical waveguide member installed on the cladding along the cladding, and the cladding is embedded in a recessed cavity formed in the upper part of the probe body. A method for manufacturing the neural probe array includes forming the cavity in an upper part of a first substrate, embedding the cladding in the cavity, forming the optical waveguide member on the cladding along the cladding, and forming the probe body by cutting the first substrate off.

Abstract: A manufacturing method of a wire including: forming a lower layer on a substrate; forming a middle layer on the lower layer; forming an upper layer on the middle layer; forming, exposing, and developing a photoresist layer on the upper layer to form a photoresist pattern; and etching the upper layer, the middle layer, and the lower layer by using the photoresist pattern as a mask to form a wire such that the upper layer covers an end of the middle layer.

Abstract: A lighting device comprises: a heat sink which comprises one surface and a receiving recess; a light emitting module which is disposed on the one surface of the heat sink and comprises a substrate and a plurality of light sources disposed on the substrate, wherein the substrate has a first hole disposed at the center thereof and a second hole; a power controller which is electrically connected to the light emitting module through the second hole of the substrate and is disposed in the receiving recess of the heat sink, wherein the light emitting module comprises a first light emitting module comprising a first substrate and a first light source, and a second light emitting module comprising a second substrate and a second light source, wherein the first substrate and the second substrate are disposed adjacent to each other.

Abstract: A light emitting diode package including a package body with a cavity, a plurality of light emitting diode (LED) chips in the cavity, a plurality of wires connected to the plurality of LED chips, and a plurality of lead frames in the package body, wherein the lead frames comprise a first lead frame electrically connected to a first electrode of a first LED chip, a second lead frame electrically connected to a second electrode of the first LED chip and a second electrode of a second LED chip, a third lead frame electrically connected to a first electrode of the second LED chip, and fourth lead frame electrically connected to a second electrode of a third LED chip. Further, ends of the lead frames are exposed outside of the package body and penetrate the package body, and the first electrodes are P electrodes and the second electrodes are N electrodes.

Abstract: An electronic device and a method that may provide security using complex biometric information are provided. The electronic device includes a sensor module configured to sense two or more pieces of biometric information and a controller configured to execute a command corresponding to biometric combination information when the biometric combination information corresponding to the two or more pieces of biometric information sensed through the sensor module exist. As described above, through use of the complex biometric information combined of two or more pieces of biometric information, more strengthened security may be provided to various objects in the electronic device.

Abstract: The present invention is related to a reinforcing member for a membrane for improving the pressure-withstanding property of the membrane having corrugations, and a membrane assembly having the reinforcing member and a method of constructing the membrane assembly. By providing a reinforcing member for a membrane having corrugations and installed in an insulating structural member of an LNG cargo, the present invention can prevent the collapse of the corrugation and attenuate shocks against a same load without increasing the facial rigidity of the corrugation, and improve the insulating property by forming an additional insulating layer.

Abstract: The present invention provides a kerf structure for a snow tire, including unit structures on each of which spiral-shaped protrusions are continuously formed to be spaced a predetermined distance apart on the outer circumferential surface of a semi-cylindrical shaped column, wherein the continuously formed unit structures are arranged by alternating convex and concave portions in a zigzag formation, which is capable of optimizing the rigidity which can maintain gripping force as an original function of a kerf while ensuring a friction force generated from small blocks of a tread portion partitioned with kerfs by collapsing a block at an optimum level and further ensuring the kerf function on snow even in the last stages of tread wear by lowering the rigidity of the blocks of the tread portion.

Abstract: The present invention relates to a kerf structure for a snow tire, including a wave-shaped straight portion and an expansion portion formed expanding from the straight portion, wherein the expansion portion includes unit structures, on each of which central semi-sphere holes and polygonal forms around the semi-sphere holes form protrusions in opposite directions are formed continuously. According to the present invention, the kerf structure for a snow tire provides a symmetric shape, thereby securing uniform block rigidity regardless of the direction of the kerf, and the interlocking effect can be maximized through the combination of the protrusion shape of the polygonal shape and the embossing of the semi-sphere hole.

Abstract: Provided is a method of manufacturing a semiconductor device. The method includes forming a sacrificial film as part of a process of forming a semiconductor device. The sacrificial film has a relatively high etch selectivity with respect to other materials of the semiconductor device so as to reduce loss of etching masks and improve the quality of a components (e.g., buried contacts) of the semiconductor device.

Abstract: Provided is a method of manufacturing a semiconductor device. The method includes forming a sacrificial film as part of a process of forming a semiconductor device. The sacrificial film has a relatively high etch selectivity with respect to other materials of the semiconductor device so as to reduce loss of etching masks and improve the quality of a components (e.g., buried contacts) of the semiconductor device.

Abstract: According to the present invention, when nicotinamide is added in a culture process for producing pluripotent stem cells from human differentiated cells, it can increase the efficiency of reprogramming and can significantly reduce the time required for induction of reprogramming. It was verified that nicotinamide inhibits the induction of senescence and oxidative stress in the reprogramming process and increases cell proliferation and mitochondrial activity to effectively improve culture conditions for induction of reprogramming. Particularly, the present invention will contribute to optimizing a process of producing induced pluripotent stem cells from a small amount of patient-specific somatic cells obtained from various sources, and thus it will significantly improve a process of developing clinically applicable personalized stem cell therapy agents and new drugs and will facilitate the practical application of these agents and drugs.

Abstract: A fluorescent lamp type light emitting apparatus is provided. The light emitting apparatus comprises a cover, a light emitting module, radiation pads, and cap parts. The cover comprises a first cover and a transmissive second cover coupled to the first cover. The light emitting module comprises a plurality of light emitting diodes in the cover. The radiation pads are disposed on the light emitting module. The cap parts comprise electrode terminals at both ends of the cover.

Abstract: Provided is a graphics processing method and apparatus using a post fragment shader. A rendering pipeline of the graphics processing apparatus may include a fragment shader that operates before a raster operator, and a post fragment shader that operates after the raster operator. Each of the fragment shader and the post fragment shader may apply a different effect to each of a plurality of fragments.

Abstract: A light emitting device package may be provided that includes: a package body which includes a first cavity and a second cavity which are formed to be depressed in at least a portion of the package body; a first light emitting device and a second light emitting device, each of which is disposed in the first cavity and the second cavity respectively; and a first fluorescent substance and a second fluorescent substance, each of which is filled in the first cavity and the second cavity respectively.

Abstract: A portable electric mist supply apparatus for liquid cosmetics is disclosed. Liquid cosmetics such as cosmetic water or the like are stored in a storing container which is detachably engaged, and the stored liquid cosmetics is discharged by a certain amount when in use, in a form of mist particles with the aid of a ultrasonic vibrator.