Abstract: According to the present invention, an image encoding apparatus comprises: a motion prediction unit which derives motion information on a current block in the form of the motion information including L0 motion information and L1 motion information; a motion compensation unit which performs a motion compensation for the current block on the basis of at least one of the L0 motion information and L1 motion information so as to generate a prediction block corresponding to the current block; and a restoration block generating unit which generates a restoration block corresponding to the current block based on the prediction block. According to the present invention, image encoding efficiency can be improved.

Abstract: The present disclosure relates to targeted genome editing in eukaryotic cells or organisms. More particularly, the present disclosure provides for Cas9/RNA complexes that may induce modifications in target endogenous nucleic acid sequences in nucleuses of eukaryotic cells. The Cas9/RNA complex may comprise a recombinant Cas9 protein including a nuclear localization signal (NLS) and a guide RNA including a crRNA and a tracrRNA. The Cas9/RNA complex may be a combination of the recombinant Cas9 protein and the guide RNA. The guide RNA may be transcribed in vitro or synthesized chemically. The target endogenous nucleic acid sequence may include a portion complementary to the crRNA of the guide RNA.

Abstract: Proposed is a 3D over-printing device for over-printing a 3D shape on an existing structure, the device including: a vat containing a light-curable material; a driving part configured to fix the existing structure and move the existing structure vertically, layer by layer, within the vat; and an optical part comprising a projector and a mirror structure, and configured to photocure an area to be cured on a surface of the light-curable material by projecting UV light in several directions simultaneously from above the surface of the light-curable material toward the surface of the light-curable material that is upward exposed and in contact with the existing structure.

Abstract: The present disclosure relates to targeted genome editing in eukaryotic cells or organisms. More particularly, the present disclosure provides compositions for inducing targeted disruption of endogenous genes in eukaryotic cells. The composition may comprise a Cas9/guide RNA complex with a Cas9 protein to which a NLS is linked, and a guide RNA having a crRNA and a tracrRNA. The crRNA may comprise i) a portion to be hybridized with a portion of the tracrRNA, and ii) a portion complementary to a target DNA of the endogenous genes. In some embodiments, the Cas/guide RNA complex may be formed in vitro before being introduced into the eukaryotic cell.

Abstract: A host includes: an index tree storing an index including information for identifying a versioning key; and an index update buffer storing a write key included in data subject to a write request and the versioning key corresponding to the write key. When a preset update condition is satisfied, the host transfers the versioning key stored in the index update buffer to the index tree, and when the index update buffer requires recovery, the host designates a recovery section of memory of the storage device including data corresponding to the versioning key which has not been updated to the index tree, to be read by a plurality of threads, reads data included in the recovery section from the storage device through the plurality of threads, and inserts the read data into the index update buffer to recover the index update buffer.

Abstract: The present invention relates to: a prime editing composition comprising a prime editor protein or a nucleic acid encoding same, and a prime editing guide RNA (pegRNA); and a prime editing method.

Abstract: An operating method of a controller that controls a memory device includes initializing a clock frequency set corresponding to clock signals provided to a plurality of operation modules included in the controller when a change in a current performance or a change in a host request pattern is detected, determining a target performance on the basis of the current performance given after the clock frequency set is initialized, determining an optimal clock frequency set, in which the current performance is able to be maintained equal to or greater than the target performance, by repeatedly performing an operation of changing at least one clock frequency included in the clock frequency set and an operation of monitoring the current performance given after the clock frequency is changed, and providing the plurality of operation modules with clock signals according to the optimal clock frequency set.

Abstract: The present disclosure is directed to multi-stage falling particle receivers and methods of falling particle heating. As the particles fall through the receiver, the particles are periodically collected and released by flow retarding devices. The periodic catch-and-release of the particles falling through the receiver reduces particle flow dispersion, increases particle opacity and solar absorption, and reduces erosion and damage to surfaces caused by direct particle impingement.

Abstract: The present invention relates to targeted genome editing in eukaryotic cells or organisms. More particularly, the present invention relates to a composition for cleaving a target DNA in eukaryotic cells or organisms comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein, and use thereof.

Abstract: The present invention relates to targeted genome editing in eukaryotic cells or organisms. More particularly, the present invention relates to a composition for cleaving a target DNA in eukaryotic cells or organisms comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein, and use thereof.

Abstract: An electrode assembly includes a first electrode; a second electrode; a separation membrane interposed between the first electrode and the second electrode, in which the first electrode, the second electrode, and the separation membrane are wound together to form a jelly-roll structure; and an auxiliary separation membrane disposed between the first electrode and the separation membrane in a center of the jelly-roll structure.

Abstract: Provided are an antibody that binds specifically to N-terminal pro-B-type natriuretic peptide (NT-proBNP) and use thereof. An antibody or antigen-binding fragment thereof, which binds specifically to an epitope of NT-proBNP including the amino acid sequence of HXLGXXX (SEQ ID NO: 2), may detect NT-proBNP, which is a heart disease biomarker, and heart disease can also be effectively diagnosed by using the same.

Abstract: Proposed is a preparation method for single-layered MXenes capable of exfoliating a single layer of MXenes from multi-layered MXenes with a high yield. One embodiment of the present disclosure provides a preparation method for single-layer MXenes, the method includes exfoliating a single layer of MXenes from multi-layered Mxenes with a Couette-Taylor reactor (CT reactor), inducing a regular flow.

Abstract: An electrode assembly includes a first electrode; a second electrode; and a first separator interposed between the first electrode and the second electrode. The first electrode, the second electrode and the first separator are wound together to form a jelly-roll structure. The first electrode includes a first portion including an innermost edge of the first electrode near a center portion of the jelly-roll structure and a second portion extending from the first portion away from the center portion of the jelly-roll structure. A thickness of the first portion is thinner than a thickness of the second portion.

Abstract: A storage device may include: a memory device including a temperature sensor; and a memory controller for acquiring, from the memory device, temperature information sensed by the temperature sensor for a temperature management period, performing a performance limiting operation of limiting the performance of the memory device according to the temperature information, calculating the temperature management period by using the temperature information, and updating the temperature management period by using history information on a performance history of the performance limiting operation.

Abstract: An electrode assembly and a secondary battery including the same are provided. The electrode assembly includes an electrode stack, in which electrodes and a separator are alternately stacked to be wound, and a temperature difference compensating member disposed at a winding center of the electrode stack such that a temperature difference between a winding outer shell and a winding center of the electrode stack is reduced. The temperature difference compensating member includes a phase change material.

Abstract: The present invention relates to: a therapeutic composition for coronavirus comprising, as an active ingredient, one peptide selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 6, and SEQ ID NO: 8 that binds to a coronavirus N-protein, a coronavirus-derived spike protein, or a fragment of the spike protein; and a composition that binds to a coronavirus N-protein comprising, as an active ingredient, the coronavirus-derived spike protein or the fragment of the spike protein. It is suggested that the peptides of the present invention, based on the understanding and targeting of the interaction of the coronavirus S protein and N protein of the present invention, have an effect that can be helpful in the treatment of coronaviruses including MERS-CoV, SARS-CoV-2, SARS-CoV, and HCoV-OC43.

Abstract: The present invention relates to a Cas9 variant or a nucleic acid encoding the same, a composition for editing a genome using Cas9 or a Cas9 variant or a nucleic acid encoding the same, and a method of editing a genome using the composition. Specifically, the present invention relates to a composition for editing a genome with excellent efficiency while reducing unwanted insertions/deletions (indels) by using a prime editing nuclease or a variant thereof, for example, Cas9 or a Cas9 variant or a nucleic acid encoding the same, and a method of editing a genome using the composition.

Abstract: The present disclosure relates to a binder solution for all-solid-state batteries. The binder solution includes a polymer binder, a first solvent, and an ion-conductive additive, wherein the ion-conductive additive includes lithium salt and a second solvent, which is different from the first solvent.

Abstract: A storage device includes a controller and nonvolatile memories. The controller receives write commands having virtual stream identifiers (IDs), receives discard commands having the virtual stream IDs, and determines a lifetime of write data to which each of the virtual stream IDs is assigned. The nonvolatile memories are accessed by the controller depending on physical stream IDs. The controller maps the virtual stream IDs and the physical stream IDs based on the lifetime of the write data.