Abstract: Disclosed herein are nanoparticles comprising a therapeutic or diagnostic agent positioned within an orthosilicate inner matrix, and a silica outer shell encapsulating the orthosilicate inner matrix. Also disclosed are methods of treating a disease in a subject comprising administering to the subject a biological carrier cell comprising the nanoparticle. Also disclosed are methods of preparing nanoparticles, methods of delivering nanoparticles comprising a therapeutic or diagnostic agent to a target cell, and methods of loading a therapeutic or diagnostic agent into a biological carrier cell.

Abstract: Disclosed are particles comprising lithium salts and methods for their use in treating inflammatory conditions.

Abstract: A system includes a memory buffer, a first data processor, a second data processor, and a controller. The first data processor performs a write operation to write data into the memory buffer and provides a first reference indicating a status or progress of the write operation. The controller provides a second reference indicating a buffer block in the memory buffer. The second data processor receives the first reference and the second reference, uses a threshold and the first reference to determine whether the buffer block contains enough data to be processed by the second data processor, obtains data to be processed from the buffer block using the second reference if the buffer block contains enough data to be processed, and processes the data obtained from the buffer block.

Abstract: An online precise control method for truncating parameters of microscale abrasive grains includes the steps of: (1) clamping an electrode and a diamond grinding wheel to form a discharge circuit, and communicating a workstation with a power supply and a controller of a numerical control machine tool; (2) feedback controlling movement parameters of the machine tool and parameters of the power supply according to pulse discharge parameters, controlling a discharge current and a discharge voltage, and calculating a number of rotations of the grinding wheel; (3) determining a maximum truncating area of a cutting edge and a maximum effective number of rotations of the grinding wheel according to grinding wheel parameters and pulse discharge parameters, and precisely controlling a truncating area of a cutting edge of abrasive grains online by the calculated number of rotations of the grinding wheel; and (4) after the calculated number of rotations of the grinding wheel reaches a target value, calculating a truncati

Abstract: A memory data migration method, apparatus, and system are provided. During memory migration, data is classified into two parts based on a hot and cold degree of the data. Hot data is directly migrated, and cold data is written into a shared storage device shared by memories. When needing to be used in a destination-end memory, the cold data may be read from the shared storage device. This reduces an amount of data that needs to be migrated to the destination-end memory, thereby improving memory migration efficiency.

Abstract: A mechanical-hydraulic integrated releasing device includes an upper joint, a lower joint and a pawl. The upper joint and the lower joint are respectively connected to two ends of the pawl. An outer side of the pawl is sleeved with a releasing sleeve capable of moving in an axial direction of the pawl. A step is arranged on an outer wall of a ratchet of the pawl. A groove matching the step is arranged on an inner wall of the releasing sleeve, and the step and the groove cooperate to limit the pawl. A releasing sleeve upper portion is arranged between the releasing sleeve and the upper joint, one end of the releasing sleeve upper portion is inserted into the releasing sleeve, and the other end is sleeved on an outer portion of the upper joint and connected to the upper joint via a start pin.

Abstract: An installation tool for forcibly inserting a first work piece into a fitting hole of a second work piece comprises a body, a holding head, a power lever, and a hammering tool. The body has a front end and a rear end opposite the front end in a longitudinal direction. The holding head is connected to the front end of the body and configured to hold the second work piece. The power lever is movably mounted on the body and extends in the longitudinal direction. The hammering tool is configured to hammer the power lever to exert an impact force on the power lever, the power lever pushing the first work piece in the longitudinal direction under the impact force to forcibly insert the first work piece into the fitting hole of the second work piece.

Abstract: The present invention provides a method for micro-grinding tip-accurately induced brittle fracture forming of a curved mirror surface. The method includes the steps of: grinding a surface of an optical glass material by means of a V-shaped tip of a diamond grinding wheel to form a V-shaped microgroove having a groove micro-tip; setting two supporting points with a distance of L therebetween on one side of the optical glass material where the microgroove is machined, providing a loading pressing head having a horizontal deviation distance of l between a loading point and the groove micro-tip on the other side of the optical glass material, and allowing the loading pressing head to perpendicularly apply a loading force F onto the optical glass material with a loading speed of v, and forming a penetrated smooth curved mirror surface within 0.3 millisecond via the loading point of the loading force F and under induction of the groove micro-tip.

Abstract: Methods and systems are described for determining an optimal access point for a client device based on the relative difference between signal strengths of wireless signals received by the client device from access points. In particular, the signal strengths of wireless signals received by a client device from access points are determined without receipt of signal strength and/or transmit power information from the client device. Instead, the signal strength difference value may be determined based on known characteristics of signals transmitted by the access points and known characteristics of signals received by the access points from the client device. This relative difference value may thereafter be used to determine an appropriate access point to provide network access to the client device.

Abstract: A coated cathode material includes a cathode active material and an interfacial layer coating the cathode active material. The interfacial layer includes a lithium-containing fluoride which includes at least one additional metal different from lithium.

Abstract: Aspects of the disclosure include an apparatus that has a first clock generator and a second clock generator. The first clock generator is configured to drive a first circuit, causing the first circuit to (i) receive a signal corresponding to an audio input, and (ii) determine whether an energy level of the signal exceeds a predetermined threshold. The second clock generator is activated when the first circuit determines that the energy level of the signal exceeds the predetermined threshold. The second clock generator is configured to drive a second circuit, causing the second circuit to determine whether the signal matches a predetermined pattern. A third circuit is activated when the second circuit determines that the signal matches the predetermined pattern.

Abstract: Photodynamic therapy systems comprising a nanoparticle that emits electromagnetic radiation having a first wavelength when irradiated with electromagnetic radiation, a photosensitizer which absorbs electromagnetic radiation of said first wavelength and a biocompatible mesoporous material are disclosed herein. In some examples, the photodynamic therapy system comprises a core comprising the nanoparticle, a first shell comprising the biocompatible mesoporous material, and a photosensitizer embedded in the first shell. Upon irradiation by, for example, X-rays, the nanoparticle can function as a transducer, converting X-ray photons to visible photons, and in turn, activating the photosensitizers. Methods of using the photodynamic therapy system are also disclosed.

Abstract: An anode includes: (1) a current collector; and (2) an interfacial layer disposed over the current collector. The interfacial layer includes a film of a layered material and a reinforcing material selectively disposed over certain regions of the film, while other regions of the film remain exposed from the reinforcing material.

Abstract: A system includes a memory buffer, a first data processor, a second data processor, and a controller. The first data processor performs a write operation to write data into the memory buffer and provides a first reference indicating a status or progress of the write operation. The controller provides a second reference indicating a buffer block in the memory buffer. The second data processor receives the first reference and the second reference, uses a threshold and the first reference to determine whether the buffer block contains enough data to be processed by the second data processor, obtains data to be processed from the buffer block using the second reference if the buffer block contains enough data to be processed, and processes the data obtained from the buffer block.

Abstract: An image processing method includes reading first image data from a memory, storing the first image data in a line buffer, processing the first image data to generate a first partial image, writing the first partial image into the memory, reading second image data from the memory, storing the second image data in the line buffer, processing the second image data to generate a second partial image, reading the first partial image from the memory, and splicing the first and the second partial images to obtain an output image. The first image data and the second image data correspond to a same original image having L rows and K columns of pixels. The first image data includes L rows and M columns of pixel data, and the second image data includes L rows and N columns of pixel data. K is larger than or equal to M plus N.

Abstract: An image processing method comprising acquiring a plurality of pixel rows of an image according to a rectangular pixel region, and storing the plurality of pixel rows as blocks in a plurality of line buffers. A pixel row is stored as a block in a storage space of the plurality of line buffers, and a number of bits of the block in a line buffer is smaller than a number of pixel columns of the image.

Abstract: The present invention provides a method for micro-grinding tip-accurately induced brittle fracture forming of a curved mirror surface. The method includes the steps of: grinding a surface of an optical glass material by means of a V-shaped tip of a diamond grinding wheel to form a V-shaped microgroove having a groove micro-tip; setting two supporting points with a distance of L therebetween on one side of the optical glass material where the microgroove is machined, providing a loading pressing head having a horizontal deviation distance of l between a loading point and the groove micro-tip on the other side of the optical glass material, and allowing the loading pressing head to perpendicularly apply a loading force F onto the optical glass material with a loading speed of ?, and forming a penetrated smooth curved mirror surface within 0.3 millisecond via the loading point of the loading force F and under induction of the groove micro-tip.

Abstract: Nanoparticles described as metal-encapsulated carbonaceous dots or M@C-dots are disclosed. Also disclosed are specific M@C-dots with gadolinium, so called Gd@C-dots. These nanoparticles are biologically inert and preclude the release of metal in biological environments. In addition, despite a dimension exceeding the commonly recognized threshold for renal clearance, the disclosed nanoparticles can be efficiently cleared via urine after systematic injection. Methods of making and using such nanoparticles are also disclosed.

Abstract: The present invention relates to a method for producing (functionalized) biaryls by employing a visible-light-driven, gold-catalyzed C—C cross-coupling reaction system involving boron- and silicon-containing aryl compounds and aryldiazonium compounds. Moreover, the present invention relates to the use of such boron- and silicon-containing aryl compounds and aryldiazonium compounds, as well as related gold catalysts, in the manufacture of (functionalized) biaryls.

Abstract: In one embodiment, a system includes a processor to determine a number P of how many multi-user groups are to be formed to promote airtime fairness for N client devices in which each one client device of the N client devices will be equally represented in the to-be-formed multi-user groups and in which each of the to-be-formed groups is to be actively considered by a scheduler for transmission purposes, the N client devices being associated with N wireless connections with an access point having multi-user simultaneous communication multiple-input multiple-output technology, define P multi-user groups with each one multi-user group of the P multi-user groups having a capacity for M client devices from the N client devices, N being greater than M, and allocate the N client devices to the P multi-user groups with each one client devices of the N client devices being equally represented in the P multi-user groups.