Abstract: Provided are a clearing and expansion method and an imaging method for biological tissue. The clearing and expansion method for biological tissue comprises: (1) degreasing a fixed biological tissue sample; (2) soaking the degreased biological tissue sample in a solution of gel monomer molecules, such that the monomer molecules permeate into the degreased biological tissue sample; (3) inducing a polymerization reaction of the monomer molecules permeating into the biological tissue sample so as to form a polymer gel; and (4) placing the biological tissue sample which has been subjected to a gelation treatment into water for expansion. The clearing and expansion method for biological tissue avoids the sample treatment steps of heating and enzymatic digestion that cause fluorescent quenching and the destruction of biological tissue, and thus has the advantages of high retention of endogenous fluorescent proteins, high mechanical strength of expanded biological tissue, a short sample treatment time, etc.

Abstract: The present invention belongs to the technical field of antibacterial drugs, and discloses a pyrrolylacylpiperidylamine compound and use thereof. The present invention in particular relates to a pyrrolylacylpiperidylamine compound and a pharmaceutically acceptable salt thereof, and use thereof in the preparation of a medicament for resisting infections with bacteria, mycoplasma or chlamydia.

Abstract: Disclosed are systems and techniques for efficient real-time codec encoding of video files. In one embodiments, the techniques include receiving one or more intra-prediction modes, each having a corresponding cost; calculating a first cost of a chroma-from-luma intra-prediction mode; calculating a second cost of the chroma-from-luma intra-prediction mode; and calculating a final cost based on the first cost and the second cost. The techniques also include selecting a final intra-prediction mode; generating, based on the selected final intra-prediction mode, a block of predicted pixels that approximates a block of source pixels of an image frame; and encoding a first alpha value in a bitstream.

Abstract: An analyzer and a control method thereof, a detection system, and a storage medium are provided. The control method of the analyzer includes: determining whether the analyzer obtains an analysis parameter corresponding to a detection chip used for detection; requesting and obtaining the analysis parameter in a case of being determined that the analyzer does not obtain the analysis parameter; and performing detection on the detection chip and analyzing a substance to be analyzed contained in the detection chip by using the analysis parameter to obtain analysis data of the substance to be analyzed in a case of being determined that the analyzer obtains the analysis parameter.

Abstract: Provided are a silicate modified manganese-based material and a preparation method and application thereof. The silicate modified manganese-based material has a nanoscale needle like structure, and is prepared from a solution containing a manganese source and a soluble silicate source through an oxidation-reduction reaction and then a hydrothermal reaction. The manganese source includes a divalent manganese source and a heptavalent manganese source, with Mn (II) and Mn (VII) in a molar ratio of 0.5-5.5 to 1. The present disclosure uses silicate to regulate manganese oxides, significantly reducing the particle size of the manganese-based material, generating manganese vacancies, and changing the surface manganese valence state. An advanced oxidation system formed by the silicate modified manganese-based material and an oxidant has high removal rate and reaction rate for various organic compounds.

Abstract: Disclosed are a data loading method and apparatus for a convolution operation, a computer device, a storage medium and a computer program product. The method includes: splitting a feature image to be loaded into the cache unit into a plurality of sub-feature images; determining a target cache line corresponding to each of the sub-feature images in each of the cache lines according to a positional relationship of each of the sub-feature images in the feature image; wherein target cache lines corresponding to at least two sub-feature images with the same positional relationship are located in the same cache set, and target cache lines corresponding to at least two sub-feature images with an adjacent positional relationship are located in different cache sets; loading a data content of each of the sub-feature images into the target cache line corresponding to each of the sub-feature images.

Abstract: A method for processing commodity information includes: obtaining commodity information of a commodity, in which the commodity information includes a target commodity configuration and a configuration value; obtaining a composite structure of matching conditions associated with the commodity, in which the composite structure is a tree structure of matching conditions with respect to commodity configurations, non-leaf nodes of the tree structure are in an AND-OR relationship, leaf nodes of the tree structure store Boolean expressions, each Boolean expression includes a commodity configuration, a matching value and a matching operator; obtaining a target expression having an AND-OR relationship by traversing the matching conditions in the composite structure; and obtaining a matching result by performing a matching process based on the target expression, the target commodity configuration and the configuration value of the commodity.

Abstract: Provided is a method and system for predicting tumor mutation burden (TMB) in triple negative breast cancer (TNBC) based on nuclear scores and histopathological whole slide images (WSIs). The method includes the following steps: first, screening the histopathological WSIs of TNBC; calculating a TMB value of each patient according to gene mutation of each patient with TNBC, and dividing the TMB values into two groups with high and low TMB according to a set threshold; dividing the histopathological WSIs of TNBC into patches of a set size; screening a certain number of patches with high nuclear scores according to a nuclear score function; then building a convolutional neural network (CNN) classification model, and stochastically initializing parameters in the CNN classification model; and finally, putting the screened patches into the built CNN classification model for training, so as to automatically predict high or low TMB with the histopathological WSIs of TNBC.

Abstract: The present invention relates to an anti-BTLA antibody or an antigen-binding fragment thereof comprising: at least one light chain CDR domain selected from SEQ ID NOs: 7, 8, 9, 10, 11, 12, 16, 17, 18, 22, 23, 24, 31, 32 and 33, and/or at least one heavy chain CDR domain selected from SEQ ID NOs: 1, 2, 3, 4, 5, 6, 13, 14, 15, 19, 20, 21, 25, 26, 27, 28, 29 and 30. The present invention also relates to a nucleic acid molecule encoding the antibody or the antigen-binding fragment thereof, a corresponding expression vector and a host cell, as well as therapeutic use of the antibody or the antigen-binding fragment thereof, the nucleic acid molecule, the expression vector and the host cell.

Abstract: The invention discloses a vacuum container comprising a storage container, a connecting tray component, a top cap and two one-way exhausters. The connecting tray component air-tightly encloses a container opening of the storage container. The top cap has a pressing part, and the top cap encloses a tray opening of the connecting tray component in a manner that the pressing part is in a position corresponding to the tray opening. One of the one-way exhausters is inserted in a guiding hole of the connecting tray component to form a tray one-way exhaust passage. The other one-way exhauster is inserted in an exhausting hole to form a cap one-way exhaust passage.

Abstract: The disclosure provides a runner protection tube for steel casting and a manufacturing method thereof. The runner protection tube for steel casting is made of a slurry composition for forming the runner protection tube for steel casting, the slurry composition includes organic fibers, inorganic fibers, thermosetting resins, thermoplastic resins, inorganic particles, inorganic binders, water, a lubricating oil and a hydrating agent.

Abstract: The present disclosure discloses a method for determining a message decoding strategy and apparatus, related to the field of message decoding. After the message is acquired, the message is inputted to a preset machine learning model to determine the type of the message and the decoding strategy of the message. In response to the message being a normal message, the message is decoded based on the obtained decoding strategy and the message is released; in response to the message being a malicious message, the message is rejected, and the preset machine learning model is obtained by training multiple normal messages and malicious messages in advance. Firstly, the type of message and the decoding strategy needed are determined by machine learning model, which effectively reduces the memory occupation of the system and improves the parsing and decoding efficiency of the message.

Abstract: The present invention provides a snack food with a bar-like body and a food portion that comprises at least one type of chopped nuts, chopped grains, and chopped dried fruit wrapped at one end of the bar-like body. The food portion is bound into a solid body by means of a food binder. A nut food is applied to a bar-like body to manufacture the food into a lollipop shape, and the food portion can be stably fixed on the bar-like body by means of a special structure of a fixing end of the bar-like body. The proportions of the nuts, grains, and/or fruit in the present invention is greater than half of the weight of the food portion; thus, the food has rich nutrition, does not cause excess sugar intake, and is a snack food suitable for consumers of all ages.

Abstract: According to one embodiment, a method, computer system, and computer program product for mixed reality is provided. The present invention may include receiving one or more 3D non-eye landmarks of a user; receiving at least one voice audio of the user; using random noise sampled with a unit normal distribution as one or more noised 3D eye landmarks for the user; inputting the received one or more 3D non-eye landmarks of the user, the at least one voice audio of the user, and the one or more noised 3D eye landmarks for the user, into a trained eye landmark generative model; generating one or more 3D eye landmarks for the user using the trained eye landmark generative model; performing iterative refinement of the one or more generated 3D eye landmarks using the trained eye landmark generative model; and rendering the user's generated face model using a formed 3D face mesh.

Abstract: A method may include obtaining an original image. The method may also include determining a plurality of decomposition coefficients of the original image by decomposing the original image. The method may also include determining at least one enhancement coefficient by performing enhancement to at least one of the plurality of decomposition coefficients using a coefficient enhancement model. The method may also include generating an enhanced image corresponding to the original image based on the at least one enhancement coefficient.

Abstract: An antibody specifically binding to CD112R or an antigen binding fragment thereof, a composition comprising same, a nucleic acid molecule encoding the antibody or the antigen binding fragment thereof, a vector and a host cell for expressing the antibody or the antigen binding fragment thereof, a treatment and diagnostic method using the antibody or the antigen binding fragment thereof, and use of the antibody or the antigen binding fragment thereof.

Abstract: The present disclosure discloses a standard characteristic polypeptide sequence for quantitatively detecting casein glycomacropeptide in a polypeptide product by mass spectrometry, and belongs to the technical field of inspection and detection. According to the present disclosure, three polypeptides for quantitatively detecting the casein glycomacropeptide are obtained through screening, which have amino acid sequences shown in SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3 respectively, and are suitable for quantitatively analyzing the content of the casein glycomacropeptide in a sample to be detected. According to the present disclosure, accurate quantitative analysis of the casein glycomacropeptide is realized, and the polypeptide sequence can be used for determining whether the content of the casein glycomacropeptide in the product reaches a standard or not.

Abstract: The present disclosure provides a method for processing defect information of a product, which includes the following steps of: acquiring defect information on a current film layer and defect information on historical film layers; determining whether defect information exists at a target location of the historical film layer if defect information exists at a target location of the current film layer; if defect information exists for a corresponding location to the target location in at least one of the historical film layers, deleting the defect information detected at the target location in the current film layer; and if no defect information exists for the target location in any of the historical film layers, retaining the defect information detected at the target location in the current film layer.

Abstract: Disclosed are a brightness control apparatus and method, and a display apparatus. The brightness control apparatus includes an optical detection circuit and an integrated circuit chip connected with the optical detection circuit. The optical detection circuit includes at least one transistor, configured to detect a light intensity of light to be detected corresponding to an environment where a display panel is located, and generate an electrical signal corresponding to the light intensity of the light to be detected.

Abstract: An antenna and an electronic device are provided. The antenna includes a phase shifting unit, a reference electrode layer, and an antenna substrate; the phase shifting unit includes at least one phase shifter, each includes a first transmission structure, a second transmission structure, and a phase shifting structure therebetween; the reference electrode layer is provided with at least one and second first openings; the antenna substrate includes a first dielectric substrate, and a feed structure and at least one first radiation portion on a side of the first dielectric substrate away from the reference electrode layer; the feed structure includes at least one first and second feed ports; for each phase shifter, the first transmission structure is electrically connected to a corresponding second feed port through a corresponding first opening; and the second transmission structure is electrically connected to a corresponding first radiation portion through a corresponding second opening.