Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that bind to human CCR8, a pharmaceutical composition comprising said antibody, and use of the antibody or the composition for treating a disease, such as cancer.

Abstract: A machine learning power consumption model and process are provided for determining power consumption of computing environment resources in handling requests of an application. The process includes training the machine learning power consumption model to estimate power consumption of computing environment resources in handling requests. The training uses a training dataset derived from historical request-related data, and the training dataset includes request-related data and resource power consumption data. In addition, the process includes analyzing the requests. The analyzing includes, for a particular request of the requests, obtaining a common pattern of resource use and collecting real-time trace metrics to facilitate allocating resource use to the particular request.

Abstract: Methods, systems, and devices for wireless communication are described. A user equipment (UE) may perform a decoding operation on a downlink message for the UE. The UE may store, in a buffer of the UE, decoding information associated with the decoding operation on the downlink message based at least in part on the decoding operation on the downlink message being at least partially unsuccessful. In some examples, the UE may transmit, to a network entity, a report indicating buffer usage information of the buffer of the UE, where the buffer usage information indicates one or more parameters associated with the decoding information stored in the buffer of the UE. In some cases, the buffer usage information may indicate one or more transport blocks for which entries are present in the buffer of the UE.

Abstract: Provided is a polypeptide combination, a targeting component thereof comprising a shielding peptide, a cleavable part, an antigen-binding part and a first intein fragment, the shielding peptide and the antigen-binding part being connected by means of the cleavable part, and the antigen-binding part being directly or indirectly connected to the first intein fragment; a toxin component thereof comprises a second intein fragment and a toxin, and the second intein fragment is directly or indirectly connected to the toxin; the targeting component and the toxin component form an immunoconjugate by means of the interactive action between the first intein fragment and the second intein fragment; in the immunoconjugate, the shielding peptide and the antigen-binding part are connected by means of the cleavable part, and the antigen-binding part is connected to the toxin. Also provided are a preparation method and a pharmaceutical use for the polypeptide combination.

Abstract: This disclosure is directed to a pharmaceutical composition for treating or preventing a disease. The pharmaceutical composition can comprise a polymer-drug nanoaggregate having a polymer and at least one bioactive agent that can comprise STING polypeptide, a nucleic acid encoding said STING polypeptide, a STING inhibitor, a STING activator, a STING agonist, a STING antagonist, a STING modulating molecule, or a combination thereof. The pharmaceutical composition can be a vaccine or an adjuvant for a vaccine. This disclosure is also directed to a method for treating or preventing a disease using the pharmaceutical composition. The disease can include infectious diseases caused by viruses or other pathogens, for example, influenza, rabies, or respiratory illnesses such as severe acute respiratory syndrome (SARS) caused by coronaviruses, such as MERS-CoV, SARS-CoV, and Coronavirus Disease 2019 (COVID-19) caused by the virus SARS-CoV-2 and its variants.

Abstract: Wireless communications systems and methods related to communicating control information are provided. A method of wireless communication performed by a user equipment (UE) may include monitoring a first set of physical downlink control channel (PDCCH) candidate resources for a PDCCH communication from a network unit, receiving, from the network unit, a plurality of demodulation reference signals (DMRSs), and decoding, based on a metric associated with the plurality of demodulation reference signals (DMRSs) satisfying a threshold, the PDCCH communication.

Abstract: Provided is an antigen-binding protein having the following properties: (a) specifically binding to CDH6, and (b) having the activity of being internalized into CDH6-expressing cells by binding to CDH6. Further provided an immunoconjugate comprising an antibody or antigen binding fragment thereof that specifically binds to CDH6 and has internalization activity, a pharmaceutical product comprising the immunoconjugate and having therapeutic effects on a tumor, a method for treating a tumor using the immunoconjugate or the pharmaceutical product, and the like.

Abstract: The present invention discloses an antibody drug conjugate that targets MSLN. The present invention also disclosed a method of making the antibody drug conjugate (ADC). The present invention further discloses a novel MSLN antibody or a functional fragment thereof comprising engineered heavy and light chains.

Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) may transmit an indication of a capability of the UE to receive downlink transmissions over a plurality of component carriers with a first quantity of antennas. The UE may receive, in accordance with the indication of the capability of the UE, the downlink transmissions with at least a subset of the first quantity of antennas and over at least a subset of the plurality of component carriers.

Abstract: A method for wireless communication by a user equipment (UE) includes receiving, from a network node, a group of downlink transmissions. The method also includes forming a first hybrid automatic repeat request (HARQ)-acknowledgement (ACK) part and a second HARQ-ACK part associated with a HARQ-ACK payload in accordance with a transformation scheme. The HARQ-ACK payload may include HARQ feedback for each one of the group of downlink transmissions. A size of the second HARQ-ACK part may be a function of the first HARQ-ACK part. The method also includes separately encoding the first HARQ-ACK part and the second HARQ-ACK part. The method further includes transmitting, to the network node, the encoded first HARQ-ACK part and the encoded second HARQ-ACK part.

Abstract: The present disclosure provides a standby control signal generation circuit, including: an amplification sub-circuit connected with an input terminal of the standby control signal generation circuit and configured to receive a video signal and amplify the video signal; an XOR sub-circuit connected with the amplification sub-circuit and configured to perform an XOR operation on the amplified video signal and a ground signal; and an adjustment sub-circuit connected with the XOR sub-circuit and configured to perform a proportional adjustment on an amplitude of an output signal of the XOR sub-circuit to generate a standby control signal. The present disclosure further provides a display driving device, a display driving method and a display apparatus.

Abstract: A method of wireless communication by a user equipment (UE) includes receiving, from a network device, a number of transmissions. The method also includes generating an original hybrid automatic repeat request acknowledgement (HARQ-ACK) codebook based on whether each of the number of transmission is successfully decoded. The method further includes converting a block of k HARQ-ACK bits from the original HARQ-ACK codebook into a partition. A number of partitions for a number of blocks corresponds to quantized HARQ-ACK bits. The method still further includes transmitting the quantized HARQ-ACK bits to the network device.

Abstract: A method of wireless communication by a user equipment (UE) includes converting a block of hybrid automatic repeat request acknowledgment (HARQ-ACK) bits from an original HARQ-ACK codebook into a partition, a number of partitions for a number of blocks corresponding to quantized HARQ-ACK bits. The method also includes transforming the quantized HARQ-ACK bits into a two part HARQ-ACK payload. The method further includes separately encoding a first part and a second part of the two part HARQ-ACK payload. The method also includes transmitting, to a network node, the encoded first part and the encoded second part.

Abstract: A transmitter is provided that shapes uniformly-distributed bits into a non-uniformly distributed bits according to a parity check matrix of a linear code such that a product of the parity check matrix and the non-uniformly distributed bits equals the uniformly-distributed bits. Similarly, receiver is provided that recovers the uniformly-distributed bits from the non-uniformly distributed bits through a multiplication of the non-uniformly-distributed bits with the parity check matrix.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a first network node may receive, from a second network node, a first indication of an air interface resource configuration that is associated with the second network node. The first network node may transmit a cross link interference (CLI) measurement configuration that is addressed to a user equipment (UE) associated with the first network node, the CLI measurement configuration being associated with a CLI measurement procedure at the UE and being based at least in part on the air interface resource configuration. The first network node may receive a second indication of a CLI measurement report that is associated with the UE, the CLI measurement report including a CLI metric that is based at least in part on the CLI measurement configuration. Numerous other aspects are described.

Abstract: Methods, systems, and devices for wireless communications are described. A first wireless device may communicate an allocation of a set of time-frequency resources of a carrier for transmission of a first codeword. The first wireless device may map a first portion of the first codeword to resource elements of a first subband of the set of time-frequency resources in a frequency-first, time-second manner and a second portion of the first codeword to resource elements of a second subband of the set of time-frequency resources in the frequency-first, time-second manner. The first portion of the first codeword may include a contiguous portion of the first codeword preceding the second portion of the first codeword. The first wireless device may transmit, within the set of time-frequency resources, the first codeword based on the mapping.

Abstract: Conventional email filtering services are not suitable for recognizing sophisticated malicious emails, and therefore may allow sophisticated malicious emails to reach inboxes by mistake. Introduced here are threat detection platforms designed to take an integrative approach to detecting security threats. For example, after receiving input indicative of an approval from an individual to access past email received by employees of an enterprise, a threat detection platform can download past emails to build a machine learning (ML) model that understands the norms of communication with internal contacts (e.g., other employees) and/or external contacts (e.g., vendors). By applying the ML model to incoming email, the threat detection platform can identify security threats in real time in a targeted manner.

Abstract: This disclosure provides systems, methods, and devices for image signal processing that support improved demosaicing of color image signal. In a first aspect, a method of image processing includes receiving a first image frame and a second image frame. The method may also include determining a first demosaiced image frame by applying a first demosaic process to the first image frame and determining a second demosaiced image frame by applying a second demosaic process to the first image frame based on the second image frame. Blending weights may be determined based on the first image frame and the second image frame and a blended image frame may be determined by combining pixel values from corresponding portions of the first demosaiced image frame and the second demosaiced image frame according to the blending weights. Other aspects and features are also claimed and described.

Abstract: Methods, systems, and devices for wireless communication are described. A user equipment (UE) may transmit a random access preamble according to a cyclic shift from a first set of cyclic shifts associated with a cyclic shift step size that is less than a round trip time (RTT) of a serving cell of the UE. The UE may generate the first set of cyclic shifts based on a second set of cyclic shifts and a set of cyclic shift offsets associated with an offset step size that is less than the RTT. If a network entity detects a collision between the random access preamble and another random access preamble, the network entity may transmit a collision resolution message indicating resources for the UE to retransmit the random access preamble. Alternatively, the network entity may proceed with the random access procedure by transmitting a random access response message to the UE.

Abstract: The present invention relates to the technical field of wastewater treatment, and discloses a bioaugmentation treatment process for lithium battery producing wastewater. The method comprises the following steps: 1) introducing wastewater into a hydrolytic acidification tank, and adding Enterobacter sp. NJUST50 and activated sludge to the hydrolytic acidification tank for hydrolytic acidification treatment; 2) introducing the effluent into an anoxic tank, and adding Enterobacter sp. NJUST50 and anaerobic activated sludge for anoxic treatment; 3) introducing the effluent into an aerobic tank, and adding Enterobacter sp. NJUST50 and aerobic activated sludge for aerobic treatment; 4) introducing the effluent into an anoxic filter tank, and adding Enterobacter sp. NJUST50 and anaerobic activated sludge to the filter tank for treatment; and 5) introducing the effluent into a biological aerated filter tank, and adding a sludge mixture of Enterobacter sp.