Abstract: The present disclosure provides a method for data storage, a general service entity device, and a storage medium. The method for data storage includes: by adopting a general service entity, receiving data sent by an application entity; performing a lock setting or an overflow setting; selecting a retention strategy for previously stored data according to the lock setting or the overflow setting in the case of satisfying a data overflow condition; and storing part or all of received data according to the retention strategy.

Abstract: A priority-based resource processing method and system, belonging to the technical field of information processing, are described. The priority-based resource processing method comprises: calculating a first priority of a first resource and a second priority of a second resource; determining whether the first priority of the first resource is higher than the second priority of the second resource; and when it is determined that the first priority is higher than the second priority, responding to a first operation request corresponding to the first resource.

Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.

Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.

Abstract: The present invention relates to a multi-specific binding conjugate, a related composition and use. The binding conjugate comprises binding moieties for two or more different receptors, co-receptors, antigens or cellular markers which moieties are coupled by a nanomaterial. The multi-specific binding conjugate can be used to modulate an immune response, treat or prevent a disease or condition (e.g., a cancer, autoimmune disease, pathogen infection or inflammatory disease).

Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.

Abstract: Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a ?-lactam antibiotic.

Abstract: The present disclosure relates to a method, apparatus, system and storage medium for access control policy configuration. The method includes receiving a request for creating a target resource; determining, based on the request, whether an access control policy inheritance attribute is set for the target resource, the access control policy inheritance attribute indicating an inheritance relationship between access control policies of the target resource and its parent resource; and configuring the access control policy of the target resource according to a result of the determination. Thus, the efficiency of configuring an access control policy for a resource is improved.

Abstract: The present invention relates to the newly identified MIC-1 binding receptor, GFRAL. In vitro bioassays, for testing affinity and potency of GFRAL ligand, such as MIC- or MIC-1 variants, are provided.

Abstract: An event notification method, including: receiving an event subscription request from a subscriber, the event subscription request including at least one notified party; sending a first event notification to the at least one notified party; sending a second event notification to at least a part of the at least one notified party, the second event notification being for canceling the first event notification.

Abstract: Disclosed are a class of ?-opioid receptor agonists and a preparation method therefor and the use thereof in the field of medicine, belonging to the field of medicinal chemistry. The ?-opioid receptor agonists significantly increase the selectivity for a G protein signaling pathway, and not only can exhibit excellent pharmacodynamic effects, but also significantly improve safety.

Abstract: The present disclosure relates to a method, apparatus and storage medium for resource configuration. The method includes: receiving a request for resource creation, the request comprising a configuration rule for automatic configuration of a target resource; creating an automatic deployment resource in response to the request, wherein the automatic deployment resource includes configuration rule information derived from the configuration rule included in the request; and identifying the target resource to be configured and performing resource configuration for the identified target resource based on the configuration rule information. Thus, the efficiency of configuring a target resource is increased.

Abstract: The present disclosure relates to a subscription server, a subscription terminal and an information subscription method and system. The method includes establishing content information of a request from a first entity as first information of an event after determining that request information of the request satisfies an event notification rule in a subscription resource, obtaining second information of the event according to an associated object of the subscription resource, and sending a notification message containing the first information and the second information to a notified party of the subscription resource. The present disclosure may be applied to avoid increasing the network load of a requester and a notifying party, and ensure that an event will be handled in time after the notification message of the event is received.

Abstract: A priority-based resource processing method and system, belonging to the technical field of information processing, are described. The priority-based resource processing method comprises: calculating a first priority of a first resource and a second priority of a second resource; determining whether the first priority of the first resource is higher than the second priority of the second resource; and when it is determined that the first priority is higher than the second priority, responding to a first operation request corresponding to the first resource.

Abstract: A device and a method for measuring thermal load caused by excited state absorption in laser gain crystal are disclosed. Thermal focal lengths on the tangential and sagittal planes of the laser gain crystal are obtained by obtaining the threshold when the pump power is decreased, the optimal operating point, and cavity parameters of the single-frequency laser. Individual ABCD matrices of the laser gain crystal on the tangential plane and the sagittal plane are obtained based on thermal focal length.

Abstract: A device and a method for measuring a thermal load caused by energy transfer upconversion in a laser gain crystal. Increasing the pump power multiple times so that the power meter obtains multiple thresholds for a single-frequency laser; obtaining an average pump threshold of the output laser; obtaining cavity parameters of the single-frequency laser; obtaining thermal focal lengths on the tangential and sagittal planes of the laser gain crystal inside the single-frequency laser; obtaining individual ABCD matrices of the laser system on the tangential and the sagittal planes; obtaining a thermal load at the threshold based on the ABCD transfer matrix of the laser gain crystal on the tangential plane, the ABCD transfer matrix of the laser gain crystal on the sagittal plane, and the average pump threshold of the laser system; obtaining a thermal load caused by ETU at threshold based on the thermal load at the threshold.

Abstract: A work light includes a body, a light source head, and a battery. The body includes a mount surface for mounting the work light to a structure. The light source head is pivotably connected to the body. The light source head is opposite the mount surface of the body. The battery is removably coupled to the body. The battery includes a support surface. The support surface is disposed outside of the body. The support surface is oriented perpendicular to the mount surface.

Abstract: The present disclosure provides an information search method, apparatus, and system. The information search method includes: a search word sent by a user by using a client is received; search intention of the user is recognized according to feature information of the search word and/or search context feature information; search is performed by using a search policy corresponding to the recognized search intention and according to the search word to acquire information search results associated with the search word; and the information search results are sent to the client, so that the client displays the information search results.

Abstract: The present invention relates to a multi-specific binding conjugate, a related composition and use. The binding conjugate comprises binding moieties for two or more different receptors, co-receptors, antigens or cellular markers which moieties are coupled by a nanomaterial. The multi-specific binding conjugate can be used to modulate an immune response, treat or prevent a disease or condition (e.g., a cancer, autoimmune disease, pathogen infection or inflammatory disease).

Abstract: A multi-objective optimization method for groundwater pollution monitoring network, which mainly includes four steps: groundwater numerical value simulation, groundwater vulnerability assessment, the establishment of the monitoring network optimization model, and the solving of the optimization model. The core of the method is to establish a multi-objective optimization model aimed at establishing the least monitoring wells, monitoring the maximum pollutant concentration, and monitoring the maximum regional vulnerability value. Solving the optimization model by the algorithm and considering the relationship between the quality error and the number of monitoring wells comprehensively to determine the well number and location of the monitoring network.