Abstract: The present invention relates to the field of neurodegenerative processes and means to provide protection against the same. In particular, the present invention relates to polypeptides, fusion proteins, and other compounds interacting with the N-terminal domain of transient receptor potential melastatin subfamily member 4 (TRPM4), which are capable of interfering with NMDA receptor mediated neurotoxicity. The present invention also relates to nucleic acids encoding the aforementioned polypeptides or fusion proteins, compositions comprising the same and the use of said polypeptides, fusion proteins, and other compounds in methods for treating or preventing a disease of the human or animal body, for example in a method of treating diseases like Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD) or stroke.

Abstract: The present application discloses a traffic monitoring method, an apparatus, a device, and a storage medium, relates to fields of autonomous driving, intelligent transportation, big data. The specific implementation is: acquiring road condition information and/or vehicle state information collected by a terminal device, where the terminal device is at least one of an unmanned vehicle and an unmanned aerial vehicle; performing a data analysis on the road condition information and/or the vehicle state information, and identifying a traffic event. Through the above procedure, monitoring efficiency of the traffic state is improved.

Abstract: Methods and systems for image processing are provided. A target image may be acquired, wherein the target image may include a plurality of elements, an element of which may correspond to a pixel or a voxel. The target image may be decomposed into at least one layer, wherein the at least one layer may include a low frequency sub-image and a high frequency sub-image. The at least one layer may be transformed. The transformed layer may be reconstructed into a composite image.

Abstract: In an approach for maintaining data synchronization, a processor scans a set of data fields at each stage of a data analysis process. A processor generates a relationship tree model, wherein the set of data fields each correspond to a node in the relationship tree model. A processor prunes the relationship tree model. Responsive to an update to a data field of the set of data fields, a processor promulgates the update using the relationship tree model to generate an updated set of insight data. A processor outputs the updated set of insight data.

Abstract: Polymeric layers suitable for organic layers of electronic devices that show reduced driving voltage and/or increased luminous efficiency.

Abstract: Provided is an apparatus for enriching and screening a target object such as a cell, bacteria or biomolecule from a sample, comprising a plurality of multi-channel mesh bodies arranged in parallel, each multi-channel mesh body comprising a mesh body formed by intersecting a plurality of threads, a plurality of screen pores formed by intersecting the plurality of threads, and a capturing layer formed on the mesh body. The capturing layer comprises a capturing material specifically binding with the target object, and the screen pores of two adjacent layers of multi-channel mesh bodies are partially staggered. The present invention improves the capture rate of the target object in the case of ensuring high flux.

Abstract: Methods and systems for image processing are provided. A target image may be acquired, wherein the target image may include a plurality of elements, an element of which may correspond to a pixel or a voxel. The target image may be decomposed into at least one layer, wherein the at least one layer may include a low frequency sub-image and a high frequency sub-image. The at least one layer may be transformed. The transformed layer may be reconstructed into a composite image.

Abstract: A method is for determining at least one first characteristic value of blood in a patient. In an embodiment, the method includes acquiring, via a computed tomography device, computed tomography data of the patient for at least two energy levels of radiation using multi-energy computed tomography; defining a region of interest including blood, in at least one image data set reconstructed from the computed tomography data acquired; determining, at least in the region of interest defined, attenuation coefficients for each energy level of the at least two energy levels; performing material decomposition into at least two materials, one material of the two materials being iron, using the attenuation coefficients determined, yielding at least a fraction of iron in the region of interest defined; and determining the at least one first characteristic value, at least one of as and from the fraction of iron yielded.

Abstract: A method may include obtaining a breast image of an object that is acquired by an imaging device; determining a projection curve based on the breast image; determining a first valley point and a second valley point of the projection curve; determining a peak point of the projection curve based the first valley point and the second valley point of the projection curve; determining a first valley location, a second valley location, and a peak location in the breast image based on the peak point, the first valley point, and the second valley point of the projection curve; and determining a breast region in the breast image based on the first valley location, the second valley location, and the peak location.

Abstract: The present disclosure relates to systems, methods, computing devices, and storage media for medical examination. The medical examination system comprises: a breathing guiding apparatus configured to guide a breathing of a subject; an imaging device configured to scan the subject; and a controller coupled to the breathing guiding apparatus and configured to cause the breathing guiding apparatus to generate a breath guiding state for guiding the breathing of the subject.

Abstract: A computer-implemented method includes receiving, at a datastore having a plurality of records of a transaction-monitoring system, a first record representing a first instance of a transaction. The datastore includes a first layer and a second layer. A first record hash code, based on the first record, is compared to a template hash code set that includes one or more template hash codes, where each template hash code corresponds to a respective transaction in a set of one or more known transactions. The first record is inserted into the first layer of the datastore. The first record is inserted into the second layer of the datastore, based at least in part on the first record hash code not being found in the template hash code set.

Abstract: In an approach for maintaining data synchronization, a processor scans a set of data fields at each stage of a data analysis process. A processor generates a relationship tree model, wherein the set of data fields each correspond to a node in the relationship tree model. A processor prunes the relationship tree model. Responsive to an update to a data field of the set of data fields, a processor promulgates the update using the relationship tree model to generate an updated set of insight data. A processor outputs the updated set of insight data.

Abstract: A battery comprises a cathode, an anode and an electrolyte. The cathode comprises a cathode active material which is capable of reversibly intercalating and deintercalating a plurality of first metal ions; and a conductive agent, wherein the particle size of the conductive agent graphite is less than 50 ?m and the crystallinity of the conductive agent graphite is no less than 90%.

Abstract: Embodiments of the present disclosure disclose a method and apparatus for generating information. A specific embodiment of the method comprises: acquiring associated information of a road to be evaluated for driving difficulty; generating traffic environment information of the road based on the associated information; and inputting the traffic environment information of the road into a driving difficulty evaluation model to obtain a driving difficulty level of the road for an autonomous driving vehicle. The driving difficulty of the road for the autonomous driving vehicle is evaluated, to obtain the driving difficulty level of the road for the autonomous driving vehicle. Thus, based on a driving difficulty level of each road for the autonomous driving vehicle, the autonomous driving vehicle may select a road having a low driving difficulty level to drive.

Abstract: A method for image reconstruction may include obtaining projection data D0 generated by an imaging device by scanning an object at first angles, wherein the first angles may be a subset of second angles. The second angles may include at least short-scan angles for a system to conduct image reconstruction. The method may also include generating an image F1 based on the projection data D0. The method may also include determining, based on the image F1, projection data D1 corresponding to third angles that are a subset of the second angles and different from the first angles. The method may also include generating a final image associated with the object by performing an iteration process including one or more iterations using initial data including the image F1, the projection data D0, and the projection data D1.

Abstract: An on-demand key performance indicator (KPI) monitoring system includes an on-demand KPI structure module configured to dynamically generate an on-demand data structure of a KPI based on a KPI request input to a user interface. The KPI request includes a one or more targeted KPI objects. An agent collector module generates an on-demand KPI collection strategy based on the on-demand data structure. An object monitoring module collects KPI objects based on the on-demand KPI collection strategy. The collected KPI objects include the targeted KPI objects requested by the user, while excluding non-targeted KPI objects excluded from the user's KPI request.

Abstract: Disclosed are a functionalized mesh and fluidic apparatus for capturing cells or molecules in solution. The functionalized mesh comprises a mesh substrate and a functional layer formed on said mesh substrate, wherein the functional layer comprises capturing substances that can specifically bind with the target cells or molecules. The mesh and apparatus of the invention have high specificity, as well as high throughput, and are suitable for capturing molecules in solution or expressed at the surface of cell membranes. It is particularly suited to capture and sort circulating tumor cells.

Abstract: Disclosed is a method for capturing target cells or molecules in solution, comprising steps of: (I) getting medium containing said target cells or molecules into an apparatus comprising a capturing device for capturing said target cells or molecules; (II) getting said medium flow through said capturing device; (III) removing unbound debris, cells and molecules; (IV) getting said target cells or molecules detached from the capturing device; and (V) collecting said target cells or molecules; wherein said capturing device comprises at least one functionalized mesh comprising a mesh substrate and a functional layer formed on said mesh substrate, wherein said functional layer comprises capturing substances that can specifically bind with said target cells or molecules. The method has high specificity, as well as high throughput, and is suitable for capturing cells or molecules in a solution or expressed at the surface of cell membranes. It is particularly suited to capture and sort circulating tumor cells.

Abstract: A computer-implemented method includes receiving, at a datastore having a plurality of records of a transaction-monitoring system, a first record representing a first instance of a transaction. The datastore includes a first layer and a second layer. A first record hash code, based on the first record, is compared to a template hash code set that includes one or more template hash codes, where each template hash code corresponds to a respective transaction in a set of one or more known transactions. The first record is inserted into the first layer of the datastore. The first record is inserted into the second layer of the datastore, based at least in part on the first record hash code not being found in the template hash code set.

Abstract: A battery comprises a cathode, an anode and an electrolyte. The cathode comprises a cathode active material which is capable of reversibly intercalating and deintercalating a plurality of first metal ions; and a conductive agent, wherein the particle size of the conductive agent graphite is less than 50 ?m and the crystallinity of the conductive agent graphite is no less than 90%.