Abstract: A collision control method and apparatus, and a storage medium are provided. The method includes obtaining a collision action to be performed by a first control object in a game client and entity information of the first control object. The entity information includes first entity information representing a skeleton of the first control object, and second entity information representing a group of colliders of the first control object excluding the skeleton and driven by the skeleton. The skeleton and the group of colliders are controlled to perform the collision action of the first control object with a second control object based on the entity information.

Abstract: Methods for treating various cancers by administering one or more compounds that target the dimeric protein survivin are disclosed. Pharmaceutical compositions containing such compounds are also disclosed, along with general methods of identifying anti-cancer compounds that target oncogenic dimeric proteins.

Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Provided herein are compounds of formula (I)-(VI): wherein the variables are defined herein, processes of making them, and methods of treating cancer comprising administering such compounds.

Abstract: A high frequency time-division multi-phase power converter includes a power source, a switching circuit, a first resonant tank, a coreless transformer, a second resonant tank, an output rectifier circuit, an output load circuit and a control circuit. The switching circuit includes a first half bridge circuit and a second half bridge circuit connected in parallel. The first resonant tank includes a first resonant inductor, a first resonant capacitor and a first magnetizing inductor. The coreless transformer includes a primary side coil and a secondary side coil. The second resonant tank includes a second resonant capacitor and a second resonant inductor. The control circuit controls the switching circuit to be switched between multiple switching states, and ON states in a switching cycle of the first upper bridge switch, the first lower bridge switch, the second upper bridge switch, and the second lower bridge switch are mutually exclusive.

Abstract: A blade pitch drive comprising a driver sprocket, a driven sprocket, a toothed belt trained between the driver sprocket and driven sprocket, the toothed belt having a free span between the driver sprocket and driven sprocket, the free span having an arcuate form when the free span is in a slack condition, the toothed belt having a second span between the driver sprocket and driven sprocket in a tight condition when the free span is in a slack condition, and the free span operable as the second span and the second span operable as the free span according to an operating direction of the drive.

Abstract: A suspension particle sensing apparatus includes a first flow channel, a suspension particle concentration sensor and a suspension particle filtering assembly. The first flow channel has a first entrance and a first exit. The suspension particle concentration sensor is disposed in the first flow channel, and is located between the first entrance and the first exit. The suspension particle filtering assembly is disposed at the first entrance, and includes a casing and a suspension particle filtering structure. The casing has a first opening and a second opening. The first opening is communicated with the first entrance of the first flow channel. The suspension particle filtering structure covers the second opening.

Abstract: Provided herein are compounds of formula (I)-(VI): wherein the variables are defined herein, processes of making them, and methods of treating cancer comprising administering such compounds.

Abstract: An interleaved LLC half-bridge series resonant converter having an integrated transformer includes a power supply, a magnetic core, a first converter, a second converter and an output load circuit. The magnetic core has first and second outer columns and a center column. The first converter includes a first switch circuit, a first resonant tank, a first transformer, and a first rectifier circuit. The first transformer is coupled to the first resonant tank and includes a first primary winding wound on the first outer column and a first secondary winding wound on the second outer column. The second converter includes a second switch circuit, a second resonant tank, a second transformer and a second rectifier circuit. The second transformer is coupled to the second resonant tank and includes a second primary winding wound on the first outer column and a second secondary winding wound on the second outer column.

Abstract: An interleaved LLC half-bridge series resonant converter having an integrated transformer includes a power supply, a magnetic core, a first converter, a second converter and an output load circuit. The magnetic core has first and second outer columns and a center column. The first converter includes a first switch circuit, a first resonant tank, a first transformer, and a first rectifier circuit. The first transformer is coupled to the first resonant tank and includes a first primary winding wound on the first outer column and a first secondary winding wound on the second outer column. The second converter includes a second switch circuit, a second resonant tank, a second transformer and a second rectifier circuit. The second transformer is coupled to the second resonant tank and includes a second primary winding wound on the first outer column and a second secondary winding wound on the second outer column.

Abstract: A combination for improving intestinal micro-ecology and preventing chronic diseases includes an inulin, a galactooligosaccharide and a dietary fiber composite, wherein the ratio of the inulin, the galactooligosaccharide and the dietary fiber composite in a formula is (1-75):(1-75):(5-95). Preferably, the ratio is (10-50):(10-50):(25-50). A balanced nutritious food includes cereal flour and the ratio of the cereal flour to the combination in a formula is (50-95):(5-50). Preferably, the ratio is (70-95):(30-5). Moreover, provided is an application in preparing foods or medicaments for preventing inflammatory bowel disease, improving gastrointestinal motility and preventing constipation, preventing diabetes, preventing cardiovascular and cerebrovascular diseases, and regulating intestinal flora to enhance immune ability.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Disclosed are a heart rate detection system and a wearable device using the same. The heart rate detection system includes a light emitting unit, a light sensor and a processor. The light emitting unit emits a light to a human body. The light sensor senses a reflected light of the light and accordingly generates a first electric signal. The processor calculates the low-frequency noise signal and the high-frequency noise signal of the first electric signal, and removes them. After that, the processor executes a peak detection with respect to the first electric signal to calculate peak values of the first electric signal, and calculate a heart rate based on the time intervals among the peak values.

Abstract: An image sensing apparatus including a light source, an image sensor, at least one lens, and a wavelength selecting device is provided. The light source is configured to emit an illumination light to irradiate an object. The image sensor is configured to receive a light signal from the object and send an image signal corresponding to the light signal. The at least one lens is located on a transmission path of the light signal and between the object and the image sensor. The wavelength selecting device is located on the transmission path of the light signal and between the object and the image sensor. The wavelength selecting device has a first reflector and a second reflector, and a gap exists between the first reflector and the second reflector. The gap is adapted to be adjusted to have a first predetermined optical path length or a second predetermined optical path length.

Abstract: Methods for treating various cancers by administering one or more compounds that target the dimeric protein survivin are disclosed. Pharmaceutical compositions containing such compounds are also disclosed, along with general methods of identifying anti-cancer compounds that target oncogenic dimeric proteins. Exemplary compounds that can be used in the disclosed methods of treatment and pharmaceutical compositions have the chemical structure.

Abstract: Provided are novel compounds of Formula I: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula I and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Methods, systems, and computer readable media may facilitate the transport of content and playback position information from one media device to another. In embodiments, a wireless device such as a bi-directional remote control unit (e.g., Bluetooth, or RF4CE (radio frequency for consumer electronics)) or other device configured to receive and transmit wireless communications may be used to download, from a media device, and temporarily store information associated with content being output by the media device, wherein the information includes an identification of the content being output and an identification of a current playback or resume point within the piece of content. The wireless device may transmit the information associated with the content to a second media device, and the second media device may use the information to retrieve the piece of content identified by the information and to initiate playback of the content from the position identified by the information.

Abstract: Provided herein are optically active compounds of the formulae (ii); and (III) and pharmaceutical compositions thereof. Also provided herein are processes of making these compounds and resolving the racemic mixture or the enrichment of same with in one of its enantiomers to provide (R)- and (S)-1-(3-(3-N,N-dimethylaminocarbonyl)phenoxyl-4-nitrophenyl)-1-ethyl-N,N?-bis(ethylene)phosphoramidate, and methods of treating cancer comprising administering such compounds.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.