Abstract: A display substrate has a primary display region and a secondary display region, and the secondary display region includes an element arrangement region and a transition region. The display substrate includes: a substrate, and a pixel circuit layer and first via holes located on the substrate. The pixel circuit layer includes an active layer and a multi-layer inorganic insulating layer disposed on a side of the active layer away from the substrate. The active layer is located at least in the primary display region and at least partially surrounds the secondary display region. The multi-layer inorganic insulating layer is located at least in the primary display region and the secondary display region. The first via holes are located at least in the transition region, and penetrate at least one layer of the multi-layer inorganic insulating layer.

Abstract: The present disclosure provides a method for refining styrene by using falling film reboilers and heat pump technology to provide a heat source required by a separation column. According to the method, high-concentration gas-phase ethylbenzene separated from a top of a low pressure ethylbenzene/styrene column is directly pressurized through a compressor, or a heat pump working medium is gasified using the high-concentration gas-phase ethylbenzene separated from the top of the low pressure ethylbenzene/styrene column, and the gasified heat pump working medium is pressurized. The directly pressurized high-concentration gas-phase ethylbenzene or the indirectly gasified and pressurized high-concentration gas-phase ethylbenzene is fed into the falling film reboiler with low heat transfer temperature difference requirement to serve as a heat source of a pre-separation column and/or a styrene product column in a styrene separation process.

Abstract: Disclosed is a dual physically-driven and data-driven method for reconstructing internal response of a bridge. The method includes: obtaining acceleration response by an acceleration sensor under an action of an unknown load of the bridge; embedding a physical logic into a neural network based on a frequency response function; putting a physical formula and corresponding boundary conditions and initial conditions into a loss function as penalty terms, and limiting a space of a feasible solution accordingly; and training a neural network model, and predicting acceleration of an unknown point by inputting an acceleration response set of a known point obtained by the sensor into the network.

Abstract: The present invention relates to an anti-BTLA antibody or an antigen-binding fragment thereof comprising: at least one light chain CDR domain selected from SEQ ID NOs: 7, 8, 9, 10, 11, 12, 16, 17, 18, 22, 23, 24, 31, 32 and 33, and/or at least one heavy chain CDR domain selected from SEQ ID NOs: 1, 2, 3, 4, 5, 6, 13, 14, 15, 19, 20, 21, 25, 26, 27, 28, 29 and 30. The present invention also relates to a nucleic acid molecule encoding the antibody or the antigen-binding fragment thereof, a corresponding expression vector and a host cell, as well as therapeutic use of the antibody or the antigen-binding fragment thereof, the nucleic acid molecule, the expression vector and the host cell.

Abstract: According to some aspects, a memory includes a bit line discharge circuit and a bit line coupled to the bit line discharge circuit. The bit line discharge circuit includes a transistor, a control branch, and a first discharge branch. A gate of the transistor is connected with the control branch. One of a source or a drain of the transistor is connected with the first discharge branch. Another of the source or the drain of the transistor is connected with the bit line. The control branch is configured to turn on the transistor. The first discharge branch is configured to discharge the bit line at a set discharge speed when the transistor is turned on.

Abstract: The present invention discloses a recombinant RBD trimer protein capable of simultaneously generating cross neutralization activity for various severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic strains. The RBD trimer protein is taken as an antigen and supplemented with an adjuvant to immunize an organism, so that a high-titer neutralizing antibody aiming at various SARS-CoV-2 epidemic strains can be generated at the same time, and the antibody has a certain broad-spectrum property and can be used for treating and/or preventing SARS-CoV-2 infection and/or coronavirus disease 2019.

Abstract: An electronic map generation method and apparatus, and an electronic map are provided. The method includes: obtaining a first electronic map, where the first electronic map includes a first road junction, and the first road junction includes a first upstream lane and a first downstream lane (S301); and generating M virtual lane lines between the first upstream lane and the first downstream lane, where the M virtual lane lines are used to update the first electronic map, and M is an integer greater than or equal to 1 (S302). A virtual lane line can be generated between an upstream lane and a downstream lane at the first road junction. Further, a virtual lane line can be generated at a road junction based on a specific production requirement, to improve operation efficiency of an autonomous vehicle.

Abstract: This present disclosure provides a control method, a device, and an apparatus for a liquid cooling pipeline of a battery energy storage system. The control method comprises: monitoring, the battery energy storage system to obtain the working mode and a first temperature; determining, a thermal management mode to be turned on for the battery energy storage system and judging whether the battery energy storage system needs to perform a startup flow control, based on the first temperature and the working mode of the plurality of battery cells in each one of the battery clusters; and in response to the battery energy storage system needs to perform a startup flow control, determining a target battery cluster based on the first temperature and the thermal management mode, and turning on a flow control valve of a liquid cooling pipeline branch corresponding to the target battery cluster.

Abstract: A turnout apparatus for an overhead monorail includes a frame, an input fixed rail docking an input rail, output fixed rails each docking an output rail, and movable rails disposed between the input fixed rail and the output fixed rails. The input fixed rail is disposed at one end of the frame. The output fixed rails include a first output fixed rail and a second output fixed rail disposed at the other end of the frame. The movable rails include a first movable rail docking the input fixed rail and the first output fixed rail, and a second movable rail docking the input fixed rail and the second output fixed rail. The first and second movable rails are fixed and rotatable about a horizontal line as an axis. Directions toward which upper rail surfaces of the first movable rail and the second movable rail face differ by 180 degrees.

Abstract: The present invention provides a snack food with a bar-like body and a food portion that comprises at least one type of chopped nuts, chopped grains, and chopped dried fruit wrapped at one end of the bar-like body. The food portion is bound into a solid body by means of a food binder. A nut food is applied to a bar-like body to manufacture the food into a lollipop shape, and the food portion can be stably fixed on the bar-like body by means of a special structure of a fixing end of the bar-like body. The proportions of the nuts, grains, and/or fruit in the present invention is greater than half of the weight of the food portion; thus, the food has rich nutrition, does not cause excess sugar intake, and is a snack food suitable for consumers of all ages.

Abstract: Disclosed herein are methods of treating arrhythmogenic right ventricular cardiomyopathy in a subject, comprising administering a gene therapy construct comprising a connexin 43 sequence, wherein as a result of the administration, connexin 43 levels in at least a portion of the heart are increased.

Abstract: A pharmaceutical composition having a hypoglycemic effect, comprising: a GLP-1 receptor agonist, and a composition for promoting small-intestinal absorption; wherein the composition for promoting small-intestinal absorption comprises sodium lauryl sulfate, carbomer, chitosan, and sodium citrate. The composition for promoting small intestinal absorption according to the present invention may be prepared into a composite adjuvant, which, when combined with a GLP-1 agonist, can improve the absorption of this active ingredient in the small intestine and the like.

Abstract: The present invention provides use of an oral pharmaceutical formulation containing adrenocorticotropic hormone or its derivatives in the preparation of medications for the treatment of arthritis. In particular, the oral pharmaceutical formulation is used for the treatment of gout caused by a high uric acid level.

Abstract: The present disclosure provides a system and a method for controlling motion of a bank of elevators. The method includes accepting current requests for service by the bank of elevators, accepting a partial trajectory of a motion of a person moving in an environment serviced by the bank of elevators, and obtaining a probability of a future elevator request. The method further includes processing the partial trajectory with a neural network trained to estimate a weighted combination of probability density functions that indicates an arrival time distribution of the person, and generating a set of possible future requests jointly representing the probability of the future elevator request and the arrival time distribution. The method further includes optimizing a schedule of the bank of elevators to serve the current requests and the set of possible future requests, and controlling the bank of elevators according to the schedule.

Abstract: Systems and methods for verifying an executable portion of a published cloud image represents an unaltered version of an executable portion of a corresponding original cloud image are provided. In one embodiment, modification of a predefined portion of a cloud image by a cloud provider prior to its publication via a marketplace of the cloud provider is proactively addressed as part of (i) an automated signing process performed by a software publisher on the original cloud image prior to delivery to the cloud provider and (ii) a corresponding background verification process performed on the published cloud image on behalf of users by a management platform. The signing and verification processes are operable to exclude the predefined portion when creating their respective digests, thereby allowing the signed digest created prior to the modification to remain useful as part of a subsequent digest comparison performed by the verification process.

Abstract: An antibody specifically binding to CD112R or an antigen binding fragment thereof, a composition comprising same, a nucleic acid molecule encoding the antibody or the antigen binding fragment thereof, a vector and a host cell for expressing the antibody or the antigen binding fragment thereof, a treatment and diagnostic method using the antibody or the antigen binding fragment thereof, and use of the antibody or the antigen binding fragment thereof.

Abstract: A grapevine soil-cleaning device and engineering machinery installed with the soil-cleaning device, comprising an air blower (4), an air vent direction reversal device, a soil-retaining device, an angular sensor (7) and a controller (19). The controller (19) is connected to the air blower (4), the angular sensor (7), the air vent direction reversal device and the soil-retaining device respectively. The present device achieves non-contact soil cleaning by blowing air, and has the advantages of no harmful impact on buds and branches, one-time cleaning, and highly efficient soil cleaning. The air vent direction reversal device may achieve a consistent air-blowing direction when the grapevine soil-cleaning device moves among rows of the grapevine. The soil-retaining device may hold back the blown soil and reduce the displacement distance of the blown soil.

Abstract: A conductive adhesive film is disclosed. The conductive adhesive film includes a first film layer and a conductive particle layer. The first film layer has a plurality of electrode contact regions and a non-contact region separating the plurality of electrode contact regions. The first film layer has a plurality of gap structures, and the plurality of gap structures are located at least in the non-contact region. The conductive particle layer is located on a side of the first film layer. The conductive particle layer includes conductive particles. An orthographic projection of the conductive particles on the first film layer overlaps with at least a portion of each electrode contact region.

Abstract: The present disclosure provides a system and a method for estimating a future traffic density in an environment. The method comprises receiving, for at least one object in the environment, at least one partial trajectory and a sequence of observation vectors. The at least one object is represented by a plurality of particles. The method comprises processing the at least one partial trajectory with a trajectory prediction model to predict a location of each particle of the plurality of particles at a future time instant and processing the sequence of observation vectors with an entering particle prediction model to predict a probability of observing an entering particle at each ingress point at the future time instant. The future traffic density is estimated based on the predicted location of each particle and the predicted probability of observing the entering particle at each ingress point at the future time instant.

Abstract: A stable pharmaceutical composition containing a non-steroidal anti-inflammatory drug derivative, at least comprising a separated solid part and liquid part, the solid part comprising a therapeutically effective dose of non-steroidal anti-inflammatory drug derivative and the liquid part being a pharmaceutically acceptable solvent. After a long-term stability study (25° C.±2° C., 12 months), the stability of the solid part was good, and met the requirements of the pharmaceutical industry.