Patents by Inventor Jing Zhong

Jing Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190060774
    Abstract: A finger spinner includes a central pivot element, a spinning element pivoted around the central pivot element, and an attaching base supporting the central pivot element. The spinning element further includes a spinning body and at least two spinning vanes symmetrical connected around the spinning body and has a central hole formed in the spinning body. The central pivot element is rotatably penetrated through the central hole to pivot around the central pivot element in response to an external force. The the attaching base is adapted for attaching to a finger ring or a nail surface.
    Type: Application
    Filed: August 24, 2017
    Publication date: February 28, 2019
    Inventors: Jing ZHONG, Wei LI
  • Patent number: 9955924
    Abstract: The present disclosure relates to methods and systems for magnetic nanoparticle temperature imaging. Particularly, the present methods involve applying different combinations of magnetic fields to magnetic nanoparticles placed in a one-dimensional space, collecting AC magnetization signals of the magnetic nanoparticles, and analyzing the collected signals to obtain in vivo temperature information of the one-dimensional space. Different exciting magnetic fields are applied to the magnetic nanoparticles, so that one-dimensional temperature imaging is transformed into single-point temperature measurement of each minizone, and one-dimensional temperature imaging can be precisely and quickly achieved without knowing the concentration distribution of the magnetic nanoparticles.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: May 1, 2018
    Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Wenzhong Liu, Shiqiang Pi, Wenping Mao, Jing Zhong, Le He
  • Patent number: 9840526
    Abstract: Bromodomain-containing protein 4 (BRI)) has recently emerged as an attractive epigenetic target for anticancer therapy. Iridium(III) complexes are useful as irreversible inhibitor of BRD4. Complex 1a of the formula: is particularly useful.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: December 12, 2017
    Assignees: University of Macau, Hong Kong Baptist University, Kaohsiung Medical University
    Inventors: Chung-Hang Leung, Hai-Jing Zhong, Dik-Lung Ma, Hui-Min Wang
  • Patent number: 9688879
    Abstract: The present invention provides a cross-linking non-fluoro hydrophobic aqueous polyurethane dispersion, which is produced by selecting a compound comprising alcohols, amines, acids, saturated or unsaturated (double-bonded or epoxidized) aliphatic long chain carbon-carbon groups or polydimethylsiloxane comprising alcohol groups, amines, oxosilane to be reacted with IPDI to obtain a PU prepolymer; adding a compound having tertiary amines to neutralize the carboxylic acid of PU prepolymer and adding water to disperse the PU prepolymer; and adding a ambient temperature cross-linking agent to obtain a cross-linking hydrophobic aqueous PU dispersion of the present invention. The hydrophobic aqueous-based PU resin has no fluorine which is friendly to the environment, and may further self cross-links on its applications on fabric, paper, wood, glass and metal surfaces, respectively on drying at ambient temperature which is energy saving process.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: June 27, 2017
    Assignee: TAMKANG UNIVERSITY
    Inventors: Kan-Nan Chen, Jing-Zhong Hwang, Rei-Xin Wu, Mei-Ting Lu, Wan-Chun Cai, Chung-Yin Chen, Chia-Hsin Chen
  • Publication number: 20170145472
    Abstract: The present invention provides a method of detecting helicase activity in a test solution, providing a substrate solution containing a double-stranded DNA, wherein said double-stranded DNA is a substrate for a helicase to be detected; (b) introducing the substrate solution to the test solution to form a reaction solution; (c) applying a luminescent probe into the reaction solution to form a mixture; and (d) measuring a luminescent response of the luminescent probe in the mixture, wherein the luminescent response corresponds to the helicase activity in the test solution. The present invention also refers to a method of screening a potent luminescent probe for detecting helicase activity, and a series of luminescent Ir (III) complexes.
    Type: Application
    Filed: November 24, 2015
    Publication date: May 25, 2017
    Inventors: Dik-Lung Ma, Chung-Hang Leung, Hai-Jing Zhong, Bingyong He
  • Patent number: 9534963
    Abstract: Provided is a magnetic nano temperature measurement method under a triangle wave excitation magnetic field relating to a technical field of nano measurement.
    Type: Grant
    Filed: December 14, 2013
    Date of Patent: January 3, 2017
    Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Wenzhong Liu, Jing Zhong, Ling Jiang, Ming Yang, Pu Zhang, Ming Zhou
  • Publication number: 20160296175
    Abstract: The present disclosure relates to methods and systems for magnetic nanoparticle temperature imaging. Particularly, the present methods involve applying different combinations of magnetic fields to magnetic nanoparticles placed in a one-dimensional space, collecting AC magnetization signals of the magnetic nanoparticles, and analyzing the collected signals to obtain in vivo temperature information of the one-dimensional space. Different exciting magnetic fields are applied to the magnetic nanoparticles, so that one-dimensional temperature imaging is transformed into single-point temperature measurement of each minizone, and one-dimensional temperature imaging can be precisely and quickly achieved without knowing the concentration distribution of the magnetic nanoparticles.
    Type: Application
    Filed: April 14, 2014
    Publication date: October 13, 2016
    Inventors: Wenzhong LIU, Shiqiang PI, Wenping MAO, Jing ZHONG, Le HE
  • Publication number: 20160273971
    Abstract: Provided is a magnetic nano temperature measurement method under a triangle wave excitation magnetic field relating to a technical field of nano measurement.
    Type: Application
    Filed: December 14, 2013
    Publication date: September 22, 2016
    Inventors: Wenzhong Liu, Jing Zhong, Ling Jiang, Ming Yang, Pu Zhang, Ming Zhou
  • Patent number: 9399242
    Abstract: A method of preparing polyurethane prepolymer does not require using a toxic isocyanate monomer (manufactured by harmful phosgene) as a raw material. Epoxy resin and carbon dioxide are used as major raw materials to form cyclic carbonates to be reacted with a functional group oligomer, and then amino groups in a hydrophilic (ether group) or hydrophobic (siloxane group) diamine polymer are used for performing a ring-opening polymerization, and the microwave irradiation is used in the ring-opening polymerization to efficiently synthesize the amino-terminated PU prepolymer, and then an acrylic group at an end is added to manufacture an UV cross-linking PU (UV-PU) oligomer which can be coated onto a fabric surface, and the fabric is dried by UV radiation for a surface treatment to form a washing-resisted long lasting hydrophilic or hydrophobic PU fabric.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: July 26, 2016
    Assignee: TAMKANG UNIVERSITY (A UNIVERSITY OF TAIWAN)
    Inventors: Jing-Zhong Hwuang, Guei-Jia Chang, Jhong-Jheng Lin, Cheng-Wei Tsai, Shih-Chieh Wang, Po-Cheng Chen, Kan-Nan Chen, Jen-Taut Yeh
  • Patent number: 9301693
    Abstract: The invention discloses a method for in-vivo temperature measurement based on AC magnetization of magnetic nanoparticles, and relates to a nano test technology field. The invention positions magnetic nano agent at an area of a measured object, applies an AC excitation magnetic field to the area of the magnetic nano agent, collects an AC magnetization signal of the magnetic nano agent under the AC excitation magnetic field, detects amplitudes of odd harmonics of the AC magnetization signal, and finally calculates in-vivo temperature according to a relationship between the odd harmonics and the in-vivo temperature. The invention predetermines the relationship between the odd harmonics and the in-vivo temperature via the discrete Langevin's function and the Fourier transformation, solves the in-vivo temperature according to the relationship without considering concentration of the magnetic nanoparticles, and effective moment as temperature varies, and thus accurately detecting the in-vivo temperature.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: April 5, 2016
    Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Wenzhong Liu, Jing Zhong, Le He, Ling Jiang, Pu Zhang
  • Publication number: 20150275038
    Abstract: The present invention provides a cross-linking non-fluoro hydrophobic aqueous polyurethane dispersion, which is produced by selecting a compound comprising alcohols, amines, acids, saturated or unsaturated (double-bonded or epoxidized) aliphatic long chain carbon-carbon groups or polydimethylsiloxane comprising alcohol groups, amines, oxosilane to be reacted with IPDI to obtain a PU prepolymer; adding a compound having tertiary amines to neutralize the carboxylic acid of PU prepolymer and adding water to disperse the PU prepolymer; and adding a ambient temperature cross-linking agent to obtain a cross-linking hydrophobic aqueous PU dispersion of the present invention. The hydrophobic aqueous-based PU resin has no fluorine which is friendly to the environment, and may further self cross-links on its applications on fabric, paper, wood, glass and metal surfaces, respectively on drying at ambient temperature which is energy saving process.
    Type: Application
    Filed: June 15, 2015
    Publication date: October 1, 2015
    Inventors: Kan-Nan Chen, Jing-Zhong Hwang, Rei-Xin Wu, Mei-Ting Lu, Wan-Chun Cai, Chung-Yin Chen, Chia-Hsin Chen
  • Publication number: 20150275039
    Abstract: The present invention provides a cross-linking non-fluoro hydrophobic aqueous polyurethane dispersion, which is produced by selecting a compound comprising alcohols, amines, acids, saturated or unsaturated (double-bonded or epoxidized) aliphatic long chain carbon-carbon groups or polydimethylsiloxane comprising alcohol groups, amines, oxosilane to be reacted with IPDI to obtain a PU prepolymer; adding a compound having tertiary amines to neutralize the carboxylic acid of PU prepolymer and adding water to disperse the PU prepolymer; and adding a ambient temperature cross-linking agent to obtain a cross-linking hydrophobic aqueous PU dispersion of the present invention. The hydrophobic aqueous-based PU resin has no fluorine which is friendly to the environment, and may further self cross-links on its applications on fabric, paper, wood, glass and metal surfaces, respectively on drying at ambient temperature which is energy saving process.
    Type: Application
    Filed: June 15, 2015
    Publication date: October 1, 2015
    Inventors: Kan-Nan Chen, Jing-Zhong Hwang, Rei-Xin Wu, Mei-Ting Lu, Wan-Chun Cai, Chung-Yin Chen, Chia-Hsin Chen
  • Publication number: 20150086713
    Abstract: The present invention provides a cross-linking non-fluoro hydrophobic aqueous polyurethane dispersion, which is produced by selecting a compound comprising alcohols, amines, acids, saturated or unsaturated (double-bonded or epoxidized) aliphatic long chain carbon-carbon groups or polydimethylsiloxane comprising alcohol groups, amines, oxosilane to be reacted with IPDI to obtain a PU prepolymer; adding a compound having tertiary amines to neutralize the carboxylic acid of PU prepolymer and adding water to disperse the PU prepolymer; and adding a ambient temperature cross-linking agent to obtain a cross-linking hydrophobic aqueous PU dispersion of the present invention. The hydrophobic aqueous-based PU resin has no fluorine which is friendly to the environment, and may further self cross-links on its applications on fabric, paper, wood, glass and metal surfaces, respectively on drying at ambient temperature which is energy saving process.
    Type: Application
    Filed: December 30, 2013
    Publication date: March 26, 2015
    Applicant: Tamkang University
    Inventors: Kan-Nan Chen, Jing-Zhong Hwang, Rei-Xin Wu, Mei-Ting Lu, Wan-Chun Cai, Chung-Yin Chen, Chia-Hsin Chen
  • Publication number: 20150045691
    Abstract: The invention discloses a method for in-vivo temperature measurement based on AC magnetization of magnetic nanoparticles, and relates to a nano test technology field. The invention positions magnetic nano agent at an area of a measured object, applies an AC excitation magnetic field to the area of the magnetic nano agent, collects an AC magnetization signal of the magnetic nano agent under the AC excitation magnetic field, detects amplitudes of odd harmonics of the AC magnetization signal, and finally calculates in-vivo temperature according to a relationship between the odd harmonics and the in-vivo temperature. The invention predetermines the relationship between the odd harmonics and the in-vivo temperature via the discrete Langevin's function and the Fourier transformation, solves the in-vivo temperature according to the relationship without considering concentration of the magnetic nanoparticles, and effective moment as temperature varies, and thus accurately detecting the in-vivo temperature.
    Type: Application
    Filed: June 25, 2013
    Publication date: February 12, 2015
    Inventors: Wenzhong Liu, Jing Zhong, Le He, Ling Jiang, Pu Zhang
  • Publication number: 20140242292
    Abstract: A method of preparing polyurethane prepolymer does not require using a toxic isocyanate monomer (manufactured by harmful phosgene) as a raw material. Epoxy resin and carbon dioxide are used as major raw materials to form cyclic carbonates to be reacted with a functional group oligomer, and then amino groups in a hydrophilic (ether group) or hydrophobic (siloxane group) diamine polymer are used for performing a ring-opening polymerization, and the microwave irradiation is used in the ring-opening polymerization to efficiently synthesize the amino-terminated PU prepolymer, and then an acrylic group at an end is added to manufacture an UV cross-linking PU (UV-PU) oligomer which can be coated onto a fabric surface, and the fabric is dried by UV radiation for a surface treatment to form a washing-resisted long lasting hydrophilic or hydrophobic PU fabric.
    Type: Application
    Filed: February 24, 2014
    Publication date: August 28, 2014
    Applicant: Tamkang University
    Inventors: Jing-Zhong Hwuang, Guei-Jia Chang, Jhong-Jheng Lin, Cheng-Wei Tsai, Shih-Chieh Wang, Po-Cheng Chen, Kan-Nan Chen, Jen-Taut Yeh
  • Patent number: 8815970
    Abstract: A method of preparing polyurethane prepolymer does not require using a toxic isocyanate monomer (manufactured by harmful phosgene) as a raw material. Epoxy resin and carbon dioxide are used as major raw materials to form cyclic carbonates to be reacted with a functional group oligomer, and then amino groups in a hydrophilic (ether group) or hydrophobic (siloxane group) diamine polymer are used for performing a ring-opening polymerization, and the microwave irradiation is used in the ring-opening polymerization to efficiently synthesize the amino-terminated PU prepolymer, and then an acrylic group at an end is added to manufacture an UV cross-linking PU (UV-PU) oligomer which can be coated onto a fabric surface, and the fabric is dried by UV radiation for a surface treatment to form a washing-resisted long lasting hydrophilic or hydrophobic PU fabric.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: August 26, 2014
    Assignee: Tamkang University (A University of Taiwan)
    Inventors: Jing-Zhong Hwang, Guei-Jia Chang, Jhong-Jheng Lin, Cheng-Wei Tsai, Shih-Chieh Wang, Po-Cheng Chen, Kan-Nan Chen, Kan-Nan Chen
  • Patent number: 8498837
    Abstract: The invention discloses a paramagnetism-based remote temperature measurement method for magnetic nanoparticles, and the method comprises: applying multiple times of excited magnetic fields on the area of a magnetic nano sample, constructing an equation group between the different excited magnetic fields and corresponding magnetic susceptibilities according to the Langevin's paramagnetic theorem, and obtaining the information of temperature and sample concentration via the equation group. The invention is capable of more precisely and more quickly detecting the temperature of an object, and especially applicable for the detection of thermal motion at bio-molecular level. Experiments indicate the measurement error is less than 0.56K.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: July 30, 2013
    Assignee: Huazhong University of Science and Technology
    Inventors: Wenzhong Liu, Jing Zhong, Yin Li, Zhongzhou Du, Di Xie
  • Publication number: 20130004677
    Abstract: A method of preparing polyurethane prepolymer does not require using a toxic isocyanate monomer (manufactured by harmful phosgene) as a raw material. Epoxy resin and carbon dioxide are used as major raw materials to form cyclic carbonates to be reacted with a functional group oligomer, and then amino groups in a hydrophilic (ether group) or hydrophobic (siloxane group) diamine polymer are used for performing a ring-opening polymerization, and the microwave irradiation is used in the ring-opening polymerization to efficiently synthesize the amino-terminated PU prepolymer, and then an acrylic group at an end is added to manufacture an UV cross-linking PU (UV-PU) oligomer which can be coated onto a fabric surface, and the fabric is dried by UV radiation for a surface treatment to form a washing-resisted long lasting hydrophilic or hydrophobic PU fabric.
    Type: Application
    Filed: September 22, 2011
    Publication date: January 3, 2013
    Inventors: Jing-Zhong HWANG, Guei-Jia CHANG, Jhong-Jheng LIN, Cheng-Wei TSAI, Shih-Chieh WANG, Po-Cheng CHEN, Kan-Nan CHEN, Jen-Taut YEH
  • Publication number: 20120239341
    Abstract: The invention discloses a paramagnetism-based remote temperature measurement method for magnetic nanoparticles, and the method comprises: applying multiple times of excited magnetic fields on the area of a magnetic nano sample, constructing an equation group between the different excited magnetic fields and corresponding magnetic susceptibilities according to the Langevin's paramagnetic theorem, and obtaining the information of temperature and sample concentration via the equation group. The invention is capable of more precisely and more quickly detecting the temperature of an object, and especially applicable for the detection of thermal motion at bio-molecular level. Experiments indicate the measurement error is less than 0.56K.
    Type: Application
    Filed: March 28, 2011
    Publication date: September 20, 2012
    Applicant: Huazhong University of Science and Technology
    Inventors: Wenzhong Liu, Jing Zhong, Yin Li, Zhongzhou Du, Di Xie
  • Patent number: D820918
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: June 19, 2018
    Inventors: Jing Zhong, Wei Li