Patents by Inventor Jingwei Xie

Jingwei Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanofiber structures and methods of use thereof
    Patent number: 11951227
    Abstract: Coated and expanded, nanofiber structures are provided and methods of use thereof.
    Type: Grant
    Filed: April 4, 2022
    Date of Patent: April 9, 2024
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Jingwei Xie, Shixuan Chen, Mark Carlson
  • Nanofiber structures and methods of use thereof
    Patent number: 11946164
    Abstract: Expanded, nanofiber structures are provided as well as methods of use thereof and methods of making.
    Type: Grant
    Filed: July 19, 2022
    Date of Patent: April 2, 2024
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventor: Jingwei Xie
  • NANOFIBER COLLECTION DEVICES
    Publication number: 20230389900
    Abstract: Sample collection devices are provided as well as methods of use thereof and methods of making.
    Type: Application
    Filed: April 3, 2023
    Publication date: December 7, 2023
    Inventors: Jingwei Xie, Johnson Vitharikunnil John
  • SURFACE MODIFIED SCAFFOLDS AND METHODS OF USE THEREOF
    Publication number: 20230390456
    Abstract: Surface modified scaffolds are provided as well as methods of use thereof and methods of making.
    Type: Application
    Filed: October 25, 2021
    Publication date: December 7, 2023
    Inventor: Jingwei XIE
  • Microfiber structures and methods of synthesis and use thereof
    Patent number: 11813377
    Abstract: Three dimensional nanofiber structures are provided and methods of production thereof.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: November 14, 2023
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Jingwei Xie, Jiang Jiang
  • METHODS OF FABRICATING 3D HIERARCHICAL NANOFIBER SCAFFOLDS WITH STRUCTURAL AND/OR COMPOSITIONAL GRADIENTS
    Publication number: 20230302196
    Abstract: Nanofiber structures are provided as well as methods of use thereof and methods of making.
    Type: Application
    Filed: July 20, 2021
    Publication date: September 28, 2023
    Inventors: Jingwei XIE, Shixuan CHEN
  • NANOFIBER COLLECTION SWABS
    Publication number: 20230270599
    Abstract: Nanofiber swabs are provided as well as methods of use thereof and methods of making.
    Type: Application
    Filed: January 13, 2023
    Publication date: August 31, 2023
    Inventors: Jingwei Xie, Mark Carlson, Shixuan Chen, Alec McCarthy
  • Expanded nanofiber structures comprising electrospun nanofibers and a plurality of holes and methods of making and use thereof
    Patent number: 11738116
    Abstract: Expanded, nanofiber structures comprising electrospun nanofibers, a plurality of holes, and, optionally, cells are provided. Methods of making the nanofiber structures as well as methods of use thereof, particularly for wound healing, are also provided.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: August 29, 2023
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Jingwei Xie, Shixuan Chen, Mark Carlson
  • MULTI-LAYER HERNIA MESHES AND METHODS OF MANUFACTURE AND USE THEREOF
    Publication number: 20230130357
    Abstract: Hernia meshes are provided as well as methods of use thereof and methods of making.
    Type: Application
    Filed: April 30, 2021
    Publication date: April 27, 2023
    Inventors: Mark A. CARLSON, Jingwei XIE
  • COMPOSITIONS AND METHODS FOR COATING BONE GRAFTS
    Publication number: 20230093766
    Abstract: Coated bone grafts are provided as well as methods of use thereof and methods of making. In accordance with the instant invention, methods of preparing a coated bone graft (e.g., bone allograft) are provided. In certain embodiments, the method comprises electrospraying a composition comprising a polymer and, optionally, an agent, particularly a therapeutic agent, onto the surface of the bone graft. Therapeutic agents include, without limitation: bone stimulating agents, anti-fibrotic agents, antimicrobials, anti-inflammatory agents, and pro-angiogenesis agents.
    Type: Application
    Filed: February 8, 2021
    Publication date: March 23, 2023
    Inventors: Jingwei XIE, Xinping ZHANG
  • BIOMEDICAL PATCHES WITH ALIGNED FIBERS
    Publication number: 20230053327
    Abstract: A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.
    Type: Application
    Filed: June 25, 2021
    Publication date: February 16, 2023
    Inventors: Matthew R. MacEwan, Jingwei Xie, Zack Ray, Younan Xia
  • NANOFIBER STRUCTURES AND METHODS OF USE THEREOF
    Publication number: 20220364269
    Abstract: Expanded, nanofiber structures are provided as well as methods of use thereof and methods of making.
    Type: Application
    Filed: July 19, 2022
    Publication date: November 17, 2022
    Inventor: Jingwei Xie
  • Biomedical patches with aligned fibers
    Patent number: 11471260
    Abstract: A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: October 18, 2022
    Assignee: Washington University
    Inventors: Matthew R. MacEwan, Jingwei Xie, Zack Ray, Younan Xia
  • Methods for producing a nanofiber or microfiber structure
    Patent number: 11427936
    Abstract: Expanded, nanofiber structures are provided as well as methods of use thereof and methods of making.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: August 30, 2022
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventor: Jingwei Xie
  • Nanofiber Structures and Methods of Use Thereof
    Publication number: 20220226537
    Abstract: Coated and expanded, nanofiber structures are provided and methods of use thereof.
    Type: Application
    Filed: April 4, 2022
    Publication date: July 21, 2022
    Inventors: Jingwei Xie, Shixuan Chen, Mark Carlson
  • BIOMEDICAL PATCHES WITH ALIGNED FIBERS
    Publication number: 20220175510
    Abstract: A structure of aligned (e.g., radially and/or polygonally aligned) fibers, and systems and methods for producing and using the same. One or more structures provided may be created using an apparatus that includes one or more first electrodes that define an area and/or partially circumscribe an area. For example, a single first electrode may enclose the area, or a plurality of first electrode(s) may be positioned on at least a portion of the perimeter of the area. A second electrode is positioned within the area. Electrodes with rounded (e.g., convex) surfaces may be arranged in an array, and a fibrous structure created using such electrodes may include an array of wells at positions corresponding to the positions of the electrodes.
    Type: Application
    Filed: July 23, 2021
    Publication date: June 9, 2022
    Inventors: Matthew R. MacEwan, Jingwei Xie, Zack Ray, Younan Xia
  • Nanofiber structures and methods of use thereof
    Patent number: 11318224
    Abstract: Coated and expanded, nanofiber structures are provided and methods of use thereof.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: May 3, 2022
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Jingwei Xie, Shixuan Chen, Mark Carlson
  • Biomedical patches with aligned fibers
    Patent number: 11311366
    Abstract: A structure of aligned (e.g., radially and/or polygonally aligned) fibers, and systems and methods for producing and using the same. One or more structures provided may be created using an apparatus that includes one or more first electrodes that define an area and/or partially circumscribe an area. For example, a single first electrode may enclose the area, or a plurality of first electrode(s) may be positioned on at least a portion of the perimeter of the area. A second electrode is positioned within the area. Electrodes with rounded (e.g., convex) surfaces may be arranged in an array, and a fibrous structure created using such electrodes may include an array of wells at positions corresponding to the positions of the electrodes.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: April 26, 2022
    Assignee: Washington University
    Inventors: Matthew R. MacEwan, Jingwei Xie, Zack Ray, Younan Xia
  • ELECTROSPUN NANOFIBER-BASED DRESSINGS AND METHODS OF MANUFACTURE AND USE THEREOF
    Publication number: 20220096706
    Abstract: Nanofiber structures are provided as well as methods of use thereof and methods of making.
    Type: Application
    Filed: January 28, 2020
    Publication date: March 31, 2022
    Inventors: Jingwei XIE, Guangshun WANG
  • NANOFIBER STRUCTURES AND METHODS OF MANUFACTURE AND USE THEREOF
    Publication number: 20220023496
    Abstract: Nanofiber structures are provided as well as methods of use thereof and methods of making.
    Type: Application
    Filed: December 16, 2019
    Publication date: January 27, 2022
    Inventors: Jingwei XIE, Shixuan CHEN