Abstract: A method of analyzing genetic data based on gene ontology includes receiving, by an analysis device, gene expression data of a sample and gene expression data of reference tissue, receiving, by the analysis device, information on gene set related to at least one gene ontology term, extracting, by the analysis device, first gene expression data for genes belonging to the gene set from among the gene expression data of the sample and second gene expression data for genes belonging to the gene set from among the gene expression data of the reference tissue, and calculating, by the analysis device, a degree of variation of the sample based on the reference tissue by calculating entropy for the first gene expression data and the second gene expression data.

Abstract: The present disclosure relates to a two-vane pump for wastewater and a design method of a two-vane pump for wastewater using machine learning, and more particularly, a design method of a two-vane pump using machine learning capable of having efficiency of a target head and performing optimal design for sizes of solids that can pass through and a two-vane pump for wastewater according to the machine learning.

Abstract: Disclosed is a method of processing item sales information by an electronic apparatus including acquiring a purchase request including item information related to an item selected by a user and information related to a payment means, providing a purchase response including approval information corresponding to the purchase request before proceeding with payment through the payment means in response to the purchase request when the information related to the payment means satisfies a first condition, transmitting a release request for the item to a first server; and requesting payment for at least some of an amount corresponding to one or more purchase requests related to the payment means according to an arrival of settlement timing corresponding to the payment means.

Abstract: A semiconductor device includes a first substrate including a cell region and surrounded by an extension region, a common source plate on the first substrate, a supporter on the common source plate, a first stack structure on the supporter and including an alternately stacked first insulating film and first gate electrode, a channel hole penetrating the first stack structure, the supporter, and the common source plate on the cell region, and an electrode isolation trench spaced apart from the channel hole in a first direction on the cell region, extending in a second direction, and penetrating the first stack structure, the supporter, and the common source plate, wherein a first thickness of the supporter in a first region adjacent to the electrode isolation trench is greater than a second thickness of the supporter in a second region formed between the electrode isolation trench and the channel hole.

Abstract: Disclosed are methods of forming PN junction structures, methods of fabricating semiconductor devices using the same, and semiconductor devices fabricated by the same. The method of forming a PN junction structure includes: forming on a substrate a first material layer that includes first transition metal atoms and first chalcogen atoms, loading the first material layer into a process chamber and supplying a gas of second chalcogen atoms, and forming a second material layer by substituting the second chalcogen atoms for the first chalcogen atoms on a selected portion of the first material layer. The first material layer has one of n-type conductivity and p-type conductivity. The second material layer has the other of the n-type conductivity and the p-type conductivity.

Abstract: The present disclosure provides nanoparticles including laminarin and a near-infrared responsive photosensitizer covalently bonded thereto, and a composition for preventing, diagnosing, or treating arteriosclerosis comprising the same as an active ingredient. According to the present disclosure, not only the atherosclerotic plaque targeting and plaque-penetrating properties can be enhanced as compared to conventional photodynamic therapy, thus capable of being usefully used for in vivo imaging of atherosclerotic plaques, but also the size of atherosclerotic plaques is reduced by inducing apoptosis of macrophages in atherosclerotic plaques, thus capable of stabilizing atherosclerotic plaques.

Abstract: A seat ventilation blower may include a first housing; a second housing coupled and assembled to the first housing; an impeller inserted inside the first housing or the second housing, the impeller configured to rotate; and a circuit board body having a motor assembly coupled to the impeller to rotate the impeller wherein the circuit board body is configured to control operation of the motor assembly and installed in the housing when the first and second housings are coupled and assembled together.

Abstract: Disclosed is a method of processing item sales information by an electronic apparatus including acquiring a purchase request including item information related to an item selected by a user and information related to a payment means, providing a purchase response including approval information corresponding to the purchase request before proceeding with payment through the payment means in response to the purchase request when the information related to the payment means satisfies a first condition, transmitting a release request for the item to a first server; and requesting payment for at least some of an amount corresponding to one or more purchase requests related to the payment means according to an arrival of settlement timing corresponding to the payment means.

Abstract: Disclosed is a sample analysis method using a kernel module in a genomic module network. The method includes a step in which an analysis device utilizes gene expression data of a sample to construct a genomic module network based on entropy and a step in which the analysis device analyzes the sample, using a kernel module of a reference genomic module network and a kernel module of the genomic module network of the sample. The kernel module is a module that is lower in entropy by a reference value or greater than the other modules in the corresponding genomic module network. The entropy represents relations between multiple genes on the basis of probabilities of transcriptional states of the multiple genes.

Abstract: The present disclosure relates to a two-vane pump for wastewater and a design method of a two-vane pump for wastewater using machine learning, and more particularly, a design method of a two-vane pump using machine learning capable of having efficiency of a target head and performing optimal design for sizes of solids that can pass through and a two-vane pump for wastewater according to the machine learning.

Abstract: A semiconductor device includes a first substrate including a cell region and surrounded by an extension region, a common source plate on the first substrate, a supporter on the common source plate, a first stack structure on the supporter and including an alternately stacked first insulating film and first gate electrode, a channel hole penetrating the first stack structure, the supporter, and the common source plate on the cell region, and an electrode isolation trench spaced apart from the channel hole in a first direction on the cell region, extending in a second direction, and penetrating the first stack structure, the supporter, and the common source plate, wherein a first thickness of the supporter in a first region adjacent to the electrode isolation trench is greater than a second thickness of the supporter in a second region formed between the electrode isolation trench and the channel hole.

Abstract: A semiconductor device includes a first substrate including a cell region and surrounded by an extension region, a common source plate on the first substrate, a supporter on the common source plate, a first stack structure on the supporter and including an alternately stacked first insulating film and first gate electrode, a channel hole penetrating the first stack structure, the supporter, and the common source plate on the cell region, and an electrode isolation trench spaced apart from the channel hole in a first direction on the cell region, extending in a second direction, and penetrating the first stack structure, the supporter, and the common source plate, wherein a first thickness of the supporter in a first region adjacent to the electrode isolation trench is greater than a second thickness of the supporter in a second region formed between the electrode isolation trench and the channel hole.

Abstract: A semiconductor device includes a first substrate including a cell region and surrounded by an extension region, a common source plate on the first substrate, a supporter on the common source plate, a first stack structure on the supporter and including an alternately stacked first insulating film and first gate electrode, a channel hole penetrating the first stack structure, the supporter, and the common source plate on the cell region, and an electrode isolation trench spaced apart from the channel hole in a first direction on the cell region, extending in a second direction, and penetrating the first stack structure, the supporter, and the common source plate, wherein a first thickness of the supporter in a first region adjacent to the electrode isolation trench is greater than a second thickness of the supporter in a second region formed between the electrode isolation trench and the channel hole.

Abstract: Provided is a method of analyzing sample data based on a genomic module network by means of a computer apparatus. The method includes filtering first gene expression data for a normal or tumor tissue, which is the same tissue as a specific tissue, and second gene expression data for a target tissue to be analyzed, which is the same tissue as the specific tissue, on the basis of a specific module among a plurality of genomic modules; and classifying genes into a plurality of new genomic modules on the basis of an entropy determined using the filtered first gene expression data and determining, for genes belonging to at least one of the plurality of new genomic modules, a first degree of variation of the target tissue relative to the normal or tumor tissue in the at least one genomic module using the filtered first gene expression data and the filtered second gene expression data.

Abstract: Provided is a method of analyzing sample data based on a genomic module network by means of a computer apparatus. The method includes filtering first gene expression data for a normal or tumor tissue, which is the same tissue as a specific tissue, and second gene expression data for a target tissue to be analyzed, which is the same tissue as the specific tissue, on the basis of a specific module among a plurality of genomic modules; and classifying genes into a plurality of new genomic modules on the basis of an entropy determined using the filtered first gene expression data and determining, for genes belonging to at least one of the plurality of new genomic modules, a first degree of variation of the target tissue relative to the normal or tumor tissue in the at least one genomic module using the filtered first gene expression data and the filtered second gene expression data.

Abstract: A seat ventilation blower may include a first housing; a second housing coupled and assembled to the first housing; an impeller inserted inside the first housing or the second housing, the impeller configured to rotate; and a circuit board body having a motor assembly coupled to the impeller to rotate the impeller wherein the circuit board body is configured to control operation of the motor assembly and installed in the housing when the first and second housings are coupled and assembled together.

Abstract: Provided is a regenerative blower. According to an illustrative embodiment of the present invention, the regenerative blower comprises an impeller comprising a plurality of blades disposed spaced apart in the circumferential direction, wherein, in the plurality of blades, each blade gap is arranged at an incremental angle (??i).

Abstract: The present disclosure relates to a novel tetrahydropyridine derivative compound, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, methods for preparing the compounds, methods for inhibiting UDP-3-O—(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), methods for treating Gram-negative bacterial infections, the use of the compounds for the preparation of therapeutic medicaments for treating Gram-negative bacterial infections, and pharmaceutical compositions for prevention or treatment of Gram-negative bacterial infections, which contain the compounds. The compounds represented by formula I, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present disclosure can exhibit excellent effects on the treatment bacterial infections.

Abstract: The present disclosure relates to a novel tetrahydropyridine derivative compound, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, methods for preparing the compounds, methods for inhibiting UDP-3-O—(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), methods for treating Gram-negative bacterial infections, the use of the compounds for the preparation of therapeutic medicaments for treating Gram-negative bacterial infections, and pharmaceutical compositions for prevention or treatment of Gram-negative bacterial infections, which contain the compounds. The compounds represented by formula I, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present disclosure can exhibit excellent effects on the treatment bacterial infections.