Abstract: The present invention provides RUT analogs with various biological activities. In particular, the biological activities comprise anti-inflammatory activity, vasodilator effects, migration/invasion-suppressive activities, ability against damage due to remodeling between the epithelium and endothelium, collagen deposition and cardiac fibrosis suppress, Snail protein inhibitory effect, etc., which may improve cardiac, vasodilation, and lung functions. The RUT analogs disclosed herein also exhibit a lower cytotoxicity comparing to RUT.

Abstract: The present invention provides RUT analogs with various biological activities. In particular, the biological activities comprise anti-inflammatory activity, vasodilator effects, migration/invasion-suppressive activities, ability against damage due to remodeling between the epithelium and endothelium, collagen deposition and cardiac fibrosis suppress, Snail protein inhibitory effect, etc., which may improve cardiac, vasodilation, and lung functions. The RUT analogs disclosed herein also exhibit a lower cytotoxicity comparing to RUT.

Abstract: The present invention provides RUT analogs with various biological activities. In particular, the biological activities comprise anti-inflammatory activity, vasodilator effects, migration/invasion-suppressive activities, ability against damage due to remodeling between the epithelium and endothelium, collagen deposition and cardiac fibrosis suppress, Snail protein inhibitory effect, etc., which may improve cardiac, vasodilation, and lung functions. The RUT analogs disclosed herein also exhibit a lower cytotoxicity comparing to RUT.

Abstract: The present invention provides RUT analogs with various biological activities. In particular, the biological activities comprise anti-inflammatory activity, vasodilator effects, migration/invasion-suppressive activities, ability against damage due to remodeling between the epithelium and endothelium, collagen deposition and cardiac fibrosis suppress. Snail protein inhibitory effect, etc., which may improve cardiac, vasodilation, and lung functions. The RUT analogs disclosed herein also exhibit a lower cytotoxicity comparing to RUT.

Abstract: A vehicle wheel includes a wheel body having an elongated guiding slot radially extended from a center of the wheel body; and an axle centrifugal adjusting arrangement, which includes a sliding member slidably mounted along the guiding slot for mounting the wheel body to the wheel axle; and a gear adjustment device including a first gear unit mounted at the guiding slot of the wheel body, and a second gear unit mounted at the sliding member to substantially engage with the first gear unit so as to selectively adjust the sliding member to slide along the guiding slot.

Abstract: An adaptive teaching material generation system comprises a database, an authoring tool, and a course structure generator. The database provides a plurality of graphical templates for e-learning sequencing. The authoring tool provides an interface allowing one of the graphical templates to be dragged for forming a structure diagram for sequencing e-learning nodes comprised therein. The course structure generator automatically generates a course structure corresponding to the structure diagram, comprising sequencing settings of each node.

Abstract: A foldable bicycle includes a foldable bicycle frame which comprises a main frame and an enclosing frame foldably to define a receiving cavity; a front and a rear wheel assembly rotatably supported by the bicycle frame; a bicycle driving unit operatively mounted on the bicycle frame and connected to the two wheel assemblies for driving at least one of the wheel assemblies rotating; a steering unit longitudinally extended from the front wheel assembly for steering a moving direction of the front wheel assembly; and a folding arrangement. The folding arrangement includes a folding link connecting the front and the rear wheel assembly, the bicycle driving unit, the steering unit, the enclosing frame, and the main frame in a foldable manner; and a folding actuator operatively connected with the folding link in such a manner that the foldable bicycle is adapted to move between a folded position and an unfolded position.

Abstract: A rotation control brake system includes a tubular brake actuator coaxially mounted at a steering handle of a rider propelling vehicle, a brake unit operatively mounted at a position close to a driving wheel of the rider propelling vehicle, and a brake cable having a driving end coupling with the brake unit and an opposed actuating end extended to couple with the brake actuator to retain the brake actuator at a normal driving position. wherein at a braking position, the brake actuator is rotatably, longitudinally and outwardly slid with respect to the steering handle to pull the brake cable that the brake unit is biased against the driving wheel to control a rotational speed of the driving wheel, such that the rider propelling vehicle is adapted for being well controlled while the rider keeps the hand thereof at the steering handle.

Abstract: A rotation control brake system includes a tubular brake actuator coaxially mounted at a steering handle of a rider propelling vehicle, a brake unit operatively mounted at a position close to a driving wheel of the rider propelling vehicle, and a brake cable having a driving end coupling with the brake unit and an opposed actuating end extended to couple with the brake actuator to retain the brake actuator at a normal driving position. wherein at a braking position, the brake actuator is rotatably, longitudinally and outwardly slid with respect to the steering handle to pull the brake cable that the brake unit is biased against the driving wheel to control a rotational speed of the driving wheel, such that the rider propelling vehicle is adapted for being well controlled while the rider keeps the hand thereof at the steering handle.

Abstract: A safety driving equipment for a scooter, includes a twister member with a supporting arm at the end thereof opposite to the driving wheels. A universal safety wheel is mounted at the free end of the supporting arm and a transmission unit is extended to connect the twister member at a position between the safety wheel and the driving wheels. The safety wheel is capable of efficiently providing an increased safety area while the scooter in wobbling mainly to maintain the force center shifting within the safety area.

Abstract: An electrical twist vehicle includes a transmission system which enables a rider to selectively switch between electrically operated mode and manually operated mode for two rear wheels of the electrical twist vehicle by shifting a control member into a predefined position. In electrically operated mode, the two rear wheels of the electrical twist vehicle are driven by an electrical driving device whereas in manually operated mode, the two rear wheels of the electrical twist vehicle are set to free rotating. The transmission system includes a driving wheel connected to an electrical driving device, a driven wheel connected to a rear wheels axle, a transmission belt connecting the driving and driven wheel, and a biasing wheel wherein in electrically operated mode.

Abstract: A front wheel drive child riding toy vehicle including a vehicle body, a power handle rod, a front wheel set, a shaft bracket and a rear wheel set mainly aims to generate a linearly proceeding function through a forward and rearward sway of the power handle rod, a rearward moving function through a forward and rearward sway of the power handle rod after being steered at 180 degrees, a steering function through a left and right rotation of the power hand rod without affecting the linearly proceeding structure of the vehicle body and to rotate at 360 degrees in a stationary state.

Abstract: A driving shaft device of a toy twist car is disclosed. The toy twist car has a car body. A rear side of the car body has an idle wheel and a front end thereof is installed with a vertical driving shaft. A handle is installed and perpendicular to the driving shaft. A lower end of the driving shaft is vertically installed with a driving seat which is extended horizontally. A rear end of the driving seat is installed with two driving wheels at a right and left sides of the driving seat. The driving shaft is a rod body, an axial rod encloses the rod body. A lower and an upper ends of the rod body have outer threads. Surfaces of the rod body and axial rod are formed with buckling structures and a lower end of the axial rod is formed with a connecting shaft and a shoulder portion.

Abstract: A sliding twist vehicle for snowy ground. The sliding twist vehicle includes a vehicle frame, a twisting unit, a transmission unit, and a steering unit. The transmission unit has a control portion, which is extended above the vehicle frame, connected to the steering unit, and a twisting portion, which is extended below the vehicle frame, connected to the driving portion of the twisting unit. The twisting unit further has two sharp edge portions extended along the two sides of the twisting unit from the driving portion respectively, two supporting portions which are spacedly apart from the driving portion. The transmission unit is rotationally connected to the vehicle frame such that when a clockwise and an anti-clockwise movement are subsequently imparted to the steering unit, the twisting unit is twisted as a result, causing the sliding twist vehicle to slide forwardly.

Abstract: An improved steering wheel of vehicle comprises an annular shape handle connected with a central hub through a plurality of radial bars. The annular shape handle comprises a left handgrip, a right handgrip, an upper handgrip and a lower handgrip occupying four quadrants of the annular shape handle. Two bumps are arranged somewhat at 10 o'clock and 10 minutes positions of the steering wheel; and two skidproof dents are formed below the two bumps.

Abstract: A twistingly moving exerciser using the torsion of a human waist portion and the dragging of a hand portion to make a vehicle platform move forwardly in an arcuate trace mainly has a universally turning front wheel disposed in the front aspect of the said vehicle platform and a rear wheel with a thrusting effect is respectively disposed on the left and the right sides in the rear aspect thereof; when a human body sits on the vehicle platform to operate it by twisting the waist to make deflective response, the alternative movement and the thrusting effect of the two rear wheels achieve the objective of obvious moving operation.

Abstract: A twist vehicle which includes a rear operation system wherein the steering unit of twist vehicle is mounted in a relatively rear position with respect to the vehicle frame, such that a rider can drive the twist vehicle without leaning forwardly and uncomfortably. The function is achieved by connecting the steering unit by a driving member which is further mechanically connected to a driven member by a transmission belt, so that when clockwise and anti-clockwise movements are subsequently imparted to the steering unit, the motions can be transferred to the driven member which are frontwardly apart from the driving member with respect to the vehicle frame by the transmission belt, causing the twisting unit, which is connected to the driven member, to rotate according to the subsequently clockwise and anti-clockwise motions, and therefore causing the twist vehicle to move forwardly.

Abstract: The present invention provides a sliding twist vehicle for snowy ground. The sliding twist vehicle includes a vehicle frame, a twisting unit, a transmission unit, and a steering unit. The transmission unit has a control portion, which is extended above the vehicle frame, connected to the steering unit, and a twisting portion, which is extended below the vehicle frame, connected to the driving portion of the twisting unit. The twisting unit further has two sharp edge portions extended along the two sides of the twisting unit from the driving portion respectively, two supporting portions which are spacedly apart from the driving portion. The transmission unit is rotationally connected to the vehicle frame such that when a clockwise and an anti-clockwise movement are subsequently imparted to the steering unit, the twisting unit is twisted as a result, causing the sliding twist vehicle to slide forwardly.

Abstract: A twist vehicle includes a vehicle frame, a steering unit, a twisting unit and a connecting member in which when subsequent clockwise and anti-clockwise movements are imparted to the steering unit, the movements are then transferred to the twisting unit, causing the twisting unit to rotate accordingly, and therefore drive the twist vehicle to move forwardly. The twist vehicle further includes an anti-reverse system which includes at least two locking member provided to the pair of driving wheels respectively, and a pair of locking panels in which each locking panel has at least one biasing member for rotatably engaging with the locking member, so as to restrict the pair of driving wheels to be rotated in one direction only.

Abstract: The present invention relates to an operation arrangement, particularly to an operation arrangement for a twist vehicle having a sliding slot located on an end portion of an driving frame, a pivot shaft located opposite to the sliding slot, a sliding shaft with one end sliding freely along the sliding slot and another end being connected to a rocking arm, a steering shaft being connected directly and perpendicularly to the rocking arm and operated by a steering wheel. As a result, the steering wheel for the twist vehicle can be extended backwardly towards the rear portion of the operating wheels, close to the user's operation position. This arrangement can improve ease of operation by moving the steering wheel towards the user and also maintain better stability by extending the length of the wheelbase and effectively causing the center of gravity to be shifted toward the idle wheel axle.