Abstract: The present disclosure provides methods of treating cancer by administering a heterodimeric protein comprising a first monomer comprising an IL15 protein-Fc domain fusion and a second monomer comprising an IL15R? protein-Fc domain fusion.

Abstract: An air guide device for a motor vehicle having an air guide element and a movement mechanism. The air guide element forming a rear side part of a body of the motor vehicle so as to be movable relative to the remaining body. The air guide element is movable between an inoperative position and at least one operating end position. The air guide element, in its inoperative position, is flush with the remaining body. The rear side part has a flow guide surface which faces an environment of the motor vehicle and along which air flows. The air guide element has a surface which is at least part of the flow guide surface. The air guide element, in its operating end position, is configured to extend the flow guide surface along a body longitudinal axis (X) of the body.

Abstract: A drive unit for an air deflector element of a motor vehicle includes a drive motor transmission unit formed by a drive motor connected with, as a single unit, at least one transmission, a control unit configured to control the drive unit, and a temperature sensor configured to detect a temperature of the drive unit.

Abstract: An air conduction device for a motor vehicle includes an air conduction element and a movement device. The air conduction element is movably configured relative to the remaining body as at least part of a tail side part of a body of the vehicle. The air conduction element can be brought into an inoperative position and at least one final operating position. The tail side part has a flow guiding area along which air flows which is designed to face an area surrounding the motor vehicle. The air conduction element has a surface which is at least part of the flow guiding area. The air conduction element is configured in its final operating position to lengthen the flow guiding area in the direction of a longitudinal body axis (X) of the body. The air conduction element can be brought into its positions with the help of the movement device.

Abstract: An air conduction device for a motor vehicle including an air conduction element and a movement device with adjustment kinematics. The air conduction element is movable relative to the remaining body as at least part of a tail side part of the vehicle body. The air conduction element moves between an inoperative position and at least one final operating position. The tail side part has a flow guiding area along which air flows which is designed to face an area surrounding the motor vehicle. The air conduction element has a surface which is at least part of the flow guiding area. The air conduction element is configured in its final operating position to lengthen the flow guiding area in the direction of a longitudinal body axis (X) of the body. The adjustment kinematics are configured in the form of multipoint joint kinematics.

Abstract: A motor vehicle side spoiler arrangement with a spoiler blade which can be moved in a motorized manner between a retracted rest position and a laterally extended spoiler position. A spoiler shell is fixed on the vehicle and provided with a shell rear wall, a guide mechanism which guides the spoiler blade in the longitudinal direction, and an actuating motor. A sliding seal lip is provided between the spoiler blade and the shell rear wall, which sliding seal lip closes a front-side gap (S) between the spoiler blade and the shell rear wall in the spoiler position of the spoiler blade.

Abstract: A hollow filter element for insertion into an openable filter housing has a filter medium body configured as a hollow body surrounding an inwardly positioned flow space. At least one end disk is connected to the filter medium body and covers an axial end face of the filter medium body. A positioning element is arranged at the at least one end disk and interacts with a housing-associated blade of the filter housing. The positioning element receives the housing-associated blade with form fit in two different transverse directions relative to the longitudinal axis of the filter medium body. The positioning element has a positioning recess.

Abstract: The disclosure concerns a computer-implemented method of optimizing the cash level of a cash device (20), wherein the cash level indicates an amount of currency in at least one cash box of the cash device (20), wherein the method comprises the following steps: iteratively optimizing, in an automated manner, a calibration (26) of the cash device (20), wherein the calibration (26) comprises a plurality of parameters; and generating a plan (29) based at least in part on the calibration (26), wherein the plan (29) indicates when and/or how the cash device (20) is to be serviced.

Abstract: An air guide device for a motor vehicle body of a motor vehicle. The motor vehicle body has a longitudinal axis, a transverse axis, and a vertical axis. The air guide device includes: an air guide element, which is received in the motor vehicle body so as to be movable with the aid of an adjusting device, and which is movable into at least a first position and a second position. In order to effect a reduced coefficient of air resistance and an increased downforce, the air guide element has a guide element, which is configured to be movable and which is received movably on a wing top surface of the air guide element.

Abstract: A lighting device comprises a carrier having a radially outwardly facing mounting surface and an inner cavity radially within the outer mounting surface. Solid state lighting devices are mounted on the outer mounting surface and a driver is housed in the inner cavity. A ring shaped optical unit defines a light output region of the lighting device and is mounted around the carrier. An outer housing reflects light from the arrangement of solid state lighting devices to the ring shaped optical unit. This provides a compact arrangement, in which the driver, the heat sink (implemented by the carrier), and the solid state lighting arrangement are essentially in a plane. This is possible by providing a ring of light sources facing radially outwardly, with the driver mounted radially inside the ring. The radial light output is converted to a light output with a desired direction and beam shape by the optical unit.

Abstract: A filter element has a filter medium body with a first side and an oppositely positioned second side, wherein one of the first and second sides is the inflow side of the filter medium body and the other one is the outflow side of the filter medium body. A first sealing or supporting element is arranged at the first side. A second sealing or supporting element is arranged at the second side. At least one force-transmitting adhesive bead extends between the first side and the second side, wherein the at least one adhesive bead is a force transmitting element extending between the first and second sealing or supporting elements.

Abstract: The present invention concerns a cryptocurrency-cash gateway, comprising a wallet interface (403) for communicating over a network with at least one crypto wallet (102) and an EFT gateway interface (404) for communicating over a network with at least one electronic funds transfer, EFT, gateway or financial institution (407), wherein the cryptocurrency-cash gateway is operable to perform a cryptocurrency-to-cash transaction for allowing a user to withdraw cash at an automatic transaction machine, ATM (110), or a point-of-sale, POS, system (110B) by exchanging a corresponding amount of a cryptocurrency from the crypto wallet(s); or conversely allowing the user to deposit cash at an ATM or POS system and exchanging it for a corresponding amount of a cryptocurrency to be deposited in at least one crypto wallet of the user.

Abstract: An air guide device for a vehicle has: a static carrier, which is installable via installation brackets on a body structure of the vehicle, which are connected at a first portion to the body structure and at a second portion to a carrier; an air guide displaceable relative to the static carrier between a retracted rest position and a deployed operating position; a kinematic link arrangement, which has multiple links via which the air guide is displaceable relative to the carrier, wherein the links of the kinematic link arrangement are mounted on first installation brackets; and an adjusting motor, which acts on the kinematic link arrangement for the purposes of displacing the air guide relative to the carrier. The adjusting motor is mounted on a second installation bracket. The carrier, which is made of plastic, is connected by a clip connection to the installation brackets, which comprise plastic or metal.

Abstract: A drive arrangement for a motor vehicle functional part includes: a housing, in which a drive motor, a gear mechanism and an adjustor are provided at least partially; a drive shaft configured to transfer the adjustor via the gear mechanism from a closed position into an open position and vice versa; and a wrap spring arrangement comprising two wrap spring members, which act in opposite directions. The wrap spring arrangement is arranged on a gear mechanism output side, in a region of the adjustor.

Abstract: A filter element has a filter medium body with a first side and an oppositely positioned second side, wherein one of the first and second sides is the inflow side of the filter medium body and the other one is the outflow side of the filter medium body. A first sealing or supporting element is arranged at the first side. A second sealing or supporting element is arranged at the second side. At least one force-transmitting adhesive bead extends between the first side and the second side, wherein the at least one adhesive bead is a force transmitting element extending between the first and second sealing or supporting elements.

Abstract: A filter element with at least one filter medium body and with a grip configured to hold and guide the filter element is provided. At least one locking element is arranged at the grip and configured to lock the filter element on a receiving filter housing. A filter device with such a filter element has a receiving filter housing to receive the filter element and a cover to secure the locking element in locked position on the filter housing.

Abstract: A worm drive includes a rotatably mounted worm shaft, and a device for compensating an unwanted axial backlash of the worm shaft. The device for compensating the unwanted axial backlash of the worm shaft includes two pressure bodies between which the worm shaft is clamped in the axial direction by a diaphragm spring device. The diaphragm spring is assigned to one of the pressure bodies.

Abstract: A motor vehicle body includes an air-guiding unit having an air-guiding element configured to be positioned flush with the motor vehicle body and movably connected to the motor vehicle body and an adjustment unit including an actuation element arranged fixedly on a support element of the motor vehicle body and configured to aid movement of the air guiding element. The motor vehicle body further includes a receiving space configured to receive the air-guiding element, wherein the receiving space is arranged in a rear region of the motor vehicle body. The support element is designed in a form of a torsional profile for reinforcing a rear lid, forming the receiving space, of the rear region.

Abstract: The present invention relates to the reduction of oxidative stress, the improvement of the system, the provision of healthy cartilage, as well as the alleviation of pain in ruminants.

Abstract: The present invention relates to the reduction of stress in ruminants in need thereof.