Patents by Inventor Joan D. Tyner

Joan D. Tyner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20190162726
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: December 31, 2018
    Publication date: May 30, 2019
    Inventors: David J. Hawksworth, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Susan E. Brophy, Dinesh O. Shah, Joan D. Tyner, Robert N. Ziemann
  • Anti-antibodies and methods of use
    Patent number: 10215754
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: February 26, 2019
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20170023568
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: October 6, 2016
    Publication date: January 26, 2017
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Anti-antibodies and methods of use
    Patent number: 9482667
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: November 1, 2016
    Assignee: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Monoclonal antibodies to human immunodeficiency virus and uses thereof
    Patent number: 9115189
    Abstract: The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: August 25, 2015
    Assignee: ABBOTT LABORATORIES
    Inventors: Sheng C. Lou, Jeffrey C. Hunt, John G. Konrath, Xiaoxing Qiu, James W. Scheffel, Joan D. Tyner
  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20150212083
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: April 14, 2015
    Publication date: July 30, 2015
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Anti-antibodies and methods of use
    Patent number: 9073984
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: July 7, 2015
    Assignee: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • ANTIBODIES TO TROPONIN I AND METHODS OF USE THEREOF
    Publication number: 20150024457
    Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
    Type: Application
    Filed: September 5, 2014
    Publication date: January 22, 2015
    Inventors: Susan E. Brophy, Bailin Tu, Joan D. Tyner, Dagang Huang, Robert N. Ziemann
  • Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
    Patent number: 8734793
    Abstract: Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: May 27, 2014
    Assignee: Abbott Laboratories Inc.
    Inventors: Bailin Tu, Joan D. Tyner, James W. Scheffel, Michael K. White, Jeffrey M. Werneke, Robert N. Ziemann, David J. Hawksworth, Mary S. Pinkus, Robin A. Gutierrez
  • Neutrophil gelatinase-associated lipocalin (NGAL) protein isoforms enriched from urine and recombinant chinese hamster ovary (CHO) cells and related compositions, antibodies, and methods of enrichment, analysis and use
    Patent number: 8394606
    Abstract: A composition comprising neutrophil gelatinase-associated lipocalin (NGAL), which has been enriched from urine, has a molecular weight of about 24.9 kDa to about 25.9 kDa, and comprises a plurality of isoforms having isoelectric points (pIs) ranging from about 5.9 to about 9.1; a composition comprising NGAL, which has been enriched from recombinant Chinese hamster ovary (CHO) cells, has a molecular weight of about 25.9 kDa to about 27.9 kDa, and comprises a plurality of isoforms having pIs ranging from about 5.6 to about 9.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: March 12, 2013
    Assignee: Abbott Laboratories
    Inventors: Salman Ali, Ryan M. Bonn, Frank C. Grenier, Tracey D. Rae, Kevin R. Rupprecht, Hina N. Syed, Bailin Tu, Joan D. Tyner, Ryan F. Workman
  • GLYCOSYLATED MAMMALIAN NGAL AND USE THEREOF
    Publication number: 20120142022
    Abstract: The present invention relates to glycosylated mammalian NGAL, and methods of using said glycosylated mammalian NGAL.
    Type: Application
    Filed: January 19, 2012
    Publication date: June 7, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Bailin Tu, Joan D. Tyner, Lowell J. Tyner
  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20120122125
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: January 19, 2012
    Publication date: May 17, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • MONOCLONAL ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS AND USES THEREOF
    Publication number: 20120100632
    Abstract: The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
    Type: Application
    Filed: February 9, 2011
    Publication date: April 26, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Sheng C. Lou, Jeffrey C. Hunt, John G. Konrath, Xiaoxing Qiu, James W. Scheffel, Joan D. Tyner
  • ANTIBODIES TO TROPONIN I AND METHODS OF USE THEREOF
    Publication number: 20120076803
    Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
    Type: Application
    Filed: February 23, 2010
    Publication date: March 29, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, Bailin Tu, Joan D. Tyner, Lowell J. Tyner, Dagang Huang, Robert N. Ziemann
  • RECOMBINANT ANTIBODIES AGAINST HEPATITIS C VIRUS AND METHODS OF OBTAINING AND USING SAME
    Publication number: 20110263436
    Abstract: Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection.
    Type: Application
    Filed: November 22, 2010
    Publication date: October 27, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Bailin Tu, Joan D. Tyner, James W. Scheffel, Michael K. White, Jeffrey M. Werneke, Robert N. Ziemann, David J. Hawksworth, Mary S. Pinkus, Robin A. Gutierrez
  • Antibodies to troponin I and methods of use thereof
    Patent number: 8030026
    Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
    Type: Grant
    Filed: February 24, 2009
    Date of Patent: October 4, 2011
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, Bailin Tu, Joan D. Tyner, Lowell J. Tyner, legal representative, Dagang Huang, Robert N. Ziemann
  • Immunosuppressant binding antibodies and methods of obtaining and using same
    Patent number: 8022188
    Abstract: The present invention relates among other things to antibodies that immunospecifically bind to at least one agent of interest (e.g., an immunosuppressive agent), methods for producing such antibodies, and immunoassays that employ said antibodies. Additionally, the present invention also relates to methods for selecting an antibody for use in a diagnostic immunoassay and methods for selecting an antigen for use in a diagnostic immunoassay. The present invention further relates to the improvement of antibody recognition of an active parent drug in the presence of one or more of its major metabolites.
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: September 20, 2011
    Assignee: Abbott Laboratories
    Inventors: Robert W. Siegel, Joan D. Tyner, Terry Y. Nakagawa
  • Human BNP immunospecific antibodies
    Patent number: 7998480
    Abstract: The present invention relates to antibodies that immunospecifically bind to human brain natriuretic peptide or a human brain natriuretic peptide fragment with a high binding affinity, methods for producing and selecting said antibodies, immunoassays for human brain natriuretic peptide or a human brain natriuretic peptide fragment that employ said antibodies and therapeutic compositions containing said antibodies.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: August 16, 2011
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, Joan D. Tyner, Lowell J. Tyner, legal representative, Bailin X. Tu, Mary S. Pinkus, Jessie W. Shih, Bryan C. Tieman
  • Human BNP immunospecific antibodies
    Patent number: 7939069
    Abstract: The present invention relates to antibodies that immunospecifically bind to human brain natriuretic peptide or a human brain natriuretic peptide fragment with a high binding affinity, methods for producing and selecting said antibodies, immunoassays for human brain natriuretic peptide or a human brain natriuretic peptide fragment that employ said antibodies and therapeutic compositions containing said antibodies.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: May 10, 2011
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, Joan D. Tyner, Bryan C. Tieman
  • Methods for the detection of HIV-1 or -2 antigens employing monoclonal antibodies that recognize a shared HIV-1/-2 epitope in the capsid p24/p26 proteins
    Patent number: 7897332
    Abstract: The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: March 1, 2011
    Assignee: Abbott Laboratories
    Inventors: Sheng C. Lou, Jeffrey C. Hunt, John G. Konrath, Xiaoxing Qiu, James W. Scheffel, Joan D. Tyner