Patents by Inventor Joel R. Walker

Joel R. Walker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THIENOPYRROLE COMPOUNDS AND USES THEREOF
    Publication number: 20160376568
    Abstract: Thienopyrrole compounds that may inhibit Oplophorus-derived luciferases are disclosed, as well as compositions and kits comprising the thienopyrrole compounds, and methods of using the thienopyrrole compounds.
    Type: Application
    Filed: June 24, 2016
    Publication date: December 29, 2016
    Inventors: Sarah Duellman, Matthew B. Robers, Joel R. Walker, Wenhui Zhou, Chad Zimprich
  • Tricyclic compounds and PBK inhibitors containing the same
    Patent number: 9453025
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: September 27, 2016
    Assignee: OncoTherapy Science, Inc.
    Inventors: Yusuke Nakamura, Yo Matsuo, Shoji Hisada, Feryan Ahmed, Raymond Huntley, Zohreh Sajjadi-Hashemi, David M. Jenkins, Robert B. Kargbo, Wenge Cui, Polivina Jolicia F. Gauuan, Joel R. Walker, Helene Decornez, Mahender Gurram
  • C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and methods of using the same to inhibit neoplastic cell growth
    Patent number: 9359322
    Abstract: Compounds of the formula: are described, along with pharmaceutical compositions containing these compounds, and methods of using the compounds to prevent and to treat cancer in mammals, including humans.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: June 7, 2016
    Assignees: Wisconsin Alumni Research Foundation, The Ohio State University Research Foundation
    Inventors: Margaret Clagett-Dame, Robert W. Curley, Jr., Joel R. Walker, Hussein Abou-Issa, Galal A. Alshafie
  • 1,5-naphthyridine derivatives and MELK inhibitors containing the same
    Patent number: 9345709
    Abstract: The present invention directs a compound represented by formula (I).
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: May 24, 2016
    Assignee: OncoTherapy Science, Inc.
    Inventors: Yo Matsuo, Shoji Hisada, Yusuke Nakamura, Feryan Ahmed, Joel R. Walker, Raymond Huntley
  • HETEROARYL INHIBITORS OF PDE4
    Publication number: 20160137672
    Abstract: The present invention relates to compounds and methods useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of disease.
    Type: Application
    Filed: November 11, 2015
    Publication date: May 19, 2016
    Inventors: Mark E. Gurney, Timothy J. Hagen, Xuesheng Mo, A. Samuel Vellekoop, Donna L. Romero, Robert F. Campbell, Joel R. Walker, Lei Zhu
  • Heteroaryl inhibitors of PDE4
    Patent number: 9221843
    Abstract: The present invention relates to compounds and methods useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of disease.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: December 29, 2015
    Assignee: Tetra Discovery Partners, LLC
    Inventors: Mark E. Gurney, Timothy J. Hagen, Xuesheng Mo, A. Samuel Vellekoop, Donna L. Romero, Robert F. Campbell, Joel R. Walker, Lei Zhu
  • 1,5-NAPHTHYRIDINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME
    Publication number: 20150328225
    Abstract: The present invention directs a compound represented by formula (I).
    Type: Application
    Filed: May 21, 2015
    Publication date: November 19, 2015
    Inventors: Yo MATSUO, Shoji HISADA, Yusuke NAKAMURA, Feryan AHMED, Joel R. WALKER, Raymond HUNTLEY
  • Quinoline derivatives and MELK inhibitors containing the same
    Patent number: 9120749
    Abstract: The present invention directs a compound represented by formula (I).
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: September 1, 2015
    Assignee: ONCOTHERAPY SCIENCE, INC.
    Inventors: Yo Matsuo, Shoji Hisada, Yusuke Nakamura, Feryan Ahmed, Raymond Huntley, Joel R. Walker, Helene Decornez
  • Tricyclic Compounds and PBK Inhibitors Containing the Same
    Publication number: 20150183799
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Application
    Filed: December 9, 2014
    Publication date: July 2, 2015
    Inventors: Yusuke NAKAMURA, Matsuo YO, Shoji HISADA, Feryan AHMED, Raymond HUNTLEY, Zohreh SAJJADI-HASHEMI, David M. JENKINS, Robert B. KARGBO, Wenge CUI, Polivina Jolicia F. GAUUAN, Joel R. WALKER, Helene DECORNEZ, Mahender GURRAM
  • 1,5-naphthyridine derivatives and MELK inhibitors containing the same
    Patent number: 9067937
    Abstract: The present invention directs a compound represented by formula (I).
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: June 30, 2015
    Assignee: OncoTherapy Science, Inc.
    Inventors: Yo Matsuo, Shoji Hisada, Yusuke Nakamura, Feryan Ahmed, Joel R. Walker, Raymond Huntley
  • HETEROARYL INHIBITORS OF PDE4
    Publication number: 20150119362
    Abstract: The present invention relates to compounds and methods useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of disease.
    Type: Application
    Filed: October 24, 2013
    Publication date: April 30, 2015
    Inventors: Mark E. Gurney, Timothy J. Hagen, Joel R. Walker, Xuesheng Mo, A. Samuel Vellekoop, Robert Campbell, Lei Zhu, Donna L. Romero
  • Tricyclic compounds and PBK inhibitors containing the same
    Patent number: 8962648
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: February 24, 2015
    Assignee: OncoTherapy Science, Inc.
    Inventors: Yusuke Nakamura, Yo Matsuo, Shoji Hisada, Feryan Ahmed, Raymond Huntley, Zohreh Sajjadi-Hashemi, David M. Jenkins, Robert B. Kargbo, Wenge Cui, Polivina Jolicia F. Gauuan, Joel R. Walker, Helene Decornez, Mahender Gurram
  • 1,5-NAPHTHYRIDINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME
    Publication number: 20150005302
    Abstract: The present invention directs a compound represented by formula (I).
    Type: Application
    Filed: December 21, 2012
    Publication date: January 1, 2015
    Inventors: Yo Matsuo, Shoji Hisada, Yusuke Nakamura, Feryan Ahmed, Joel R. Walker, Raymond Huntley
  • QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME
    Publication number: 20130217671
    Abstract: The present invention directs a compound represented by formula (I).
    Type: Application
    Filed: July 28, 2011
    Publication date: August 22, 2013
    Inventors: Yo Matsuo, Shoji Hisada, Yusuke Nakamura, Feryan Ahmed, Raymond Huntley, Joel R. Walker, Helene Decomez
  • NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF
    Publication number: 20130184313
    Abstract: The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.
    Type: Application
    Filed: March 7, 2013
    Publication date: July 18, 2013
    Applicants: The Board of Trustees of the University of Illinois, PsychoGenics, Inc.
    Inventors: Jayaraman Chandrasekhar, Alan P. Kozikowski, Jianhua Liu, Werner Tueckmantel, Joel R. Walker, Po-wai Yuen
  • TRICYCLIC COMPOUNDS AND PBK INHIBITORS CONTAINING THE SAME
    Publication number: 20130178459
    Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.
    Type: Application
    Filed: March 29, 2011
    Publication date: July 11, 2013
    Applicant: Oncotherapy Science, Inc.
    Inventors: Yusuke Nakamura, Yo Matsuo, Shoji Hisada, Feryan Ahmed, Raymond Huntley, Zohreh Sajjadi-Hashemi, David M. Jenkins, Robert B. Kargbo, Wenge Cui, Polivina Jolicia F. Gauuan, Joel R. Walker, Helene Decornez, Mahender Gurram
  • Nicotinic acetylcholine receptor ligands and the uses thereof
    Patent number: 8445684
    Abstract: The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: May 21, 2013
    Assignees: PsycoGenics Inc., The Board of Trustee of the University of IL
    Inventors: Jayaraman Chandrasekhar, Alan P. Kozikowski, Jianhua Liu, Werner Tueckmantel, Joel R. Walker, Po-wai Yuen
  • Silent desensitizers of neuronal NACHR and methods of use thereof
    Publication number: 20110281836
    Abstract: One aspect of the present invention relates to heterocyclic compounds that are ligands for nicotinic acetylcholine receptors. A second aspect of the invention relates to the use of a compound of the invention for modulation of a mammalian nicotinic acetylcholine receptor.
    Type: Application
    Filed: November 19, 2010
    Publication date: November 17, 2011
    Applicant: PSYCHOGENICS, INC.
    Inventors: Joel R. Walker, Milton Brown, Mikell A. Paige, Yingxian Xiao, Kenneth J. Kellar
  • C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth
    Patent number: 8026220
    Abstract: Compounds of the formula: are described, along with pharmaceutical compositions containing these compounds, and methods of using the compounds to prevent and to treat cancer in mammals, including humans.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: September 27, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Margaret Clagett-Dame, Robert W. Curley, Jr., Joel R. Walker, Hussein Abou-Issa, Galal A. Alshafie
  • C-LINKED GLUCURONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHODS OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH
    Publication number: 20110212906
    Abstract: Compounds of the formula: are described, along with pharmaceutical compositions containing these compounds, and methods of using the compounds to prevent and to treat cancer in mammals, including humans.
    Type: Application
    Filed: May 12, 2011
    Publication date: September 1, 2011
    Inventors: Margaret Clagett-Dame, Robert W. Curley, JR., Joel R. Walker, Hussein Abou-Issa, Galal A. Alshafie