Patents by Inventor Johannes Eduard Maria Antonius Debets

Johannes Eduard Maria Antonius Debets has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • T CELLS FOR USE IN THERAPY
    Publication number: 20240131155
    Abstract: The invention provides inter alia an engineered T cell, wherein said T cell is engineered to express a T cell receptor (TCR) or an antibody-based receptor that binds to a T cell epitope of human ropporin-1A (ROPN1) or human ropporin-1B (ROPN1B); wherein said T cell epitope is selected from the group consisting of SEQ ID NO:4, SEQ ID NO:43, SEQ ID NO:23, SEQ ID NO:56 and SEQ ID NO:24.
    Type: Application
    Filed: January 21, 2022
    Publication date: April 25, 2024
    Inventors: Johannes Eduard Maria Antonius DEBETS, Dora Martha HAMMERL
  • Mammalian cytokines; receptors; related reagents and methods
    Patent number: 6843987
    Abstract: Nucleic acids encoding mammalian, e.g., rodent, IL-1?, IL-1?, purified IL-1? and IL-1? proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: January 18, 2005
    Assignee: Schering Corporation
    Inventors: Johannes Eduard Maria Antonius Debets, Jacqueline C. Timans, J. Fernando Bazan, Robert A. Kastelein
  • Human receptor proteins; related reagents and methods
    Publication number: 20030055218
    Abstract: Nucleic acids encoding mammalian, e.g., human receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: October 22, 2001
    Publication date: March 20, 2003
    Inventors: Jacqueline C. Timans, Johannes Eduard Maria Antonius Debets, Theodore R. Sana, J. Fernando Bazan, Robert A. Kastelein
  • Mammalian cytokines; receptors; related reagents and methods
    Publication number: 20020102234
    Abstract: Nucleic acids encoding mammalian, e.g., rodent, IL-1&dgr;, IL-1&egr;, purified IL-1&dgr; and IL-1&egr; proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: February 1, 2001
    Publication date: August 1, 2002
    Applicant: Schering Corporation, a New Jersey Corporation
    Inventors: Johannes Eduard Maria Antonius Debets, Jacqueline C. Timans, J. Fernando Bazan, Robert A. Kastelein
  • Cytokine antagonists
    Publication number: 20020068060
    Abstract: Antagonists of a cytokine signaling system have been found which exhibit favorable properties. In particular, antibody antagonists raised against the receptor are effective in blocking various signaling processes.
    Type: Application
    Filed: April 12, 2001
    Publication date: June 6, 2002
    Inventors: Johannes Eduard Maria Antonius Debets, John S. Abrams, Robert A. Kastelein, Anne O'Garra
  • Human receptor proteins; related reagents and methods
    Patent number: 6326472
    Abstract: Nucleic acids encoding mammalian, e.g., human receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: October 14, 1998
    Date of Patent: December 4, 2001
    Assignee: Schering Corporation
    Inventors: Jacqueline C. Timans, Johannes Eduard Maria Antonius Debets, Theodore R. Sana, J. Fernando Bazan, Robert A. Kastelein