Patents by Inventor Johannes-Peter Stasch

Johannes-Peter Stasch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinoxalinones and their use especially in the treatment of cardiovascular diseases
    Publication number: 20060247244
    Abstract: The invention relates to quinoxalinones and to methods for producing the same as well as the use thereof for preparing drugs for the treatment and/or prophylaxis of diseases, especially of cardiovascular diseases.
    Type: Application
    Filed: January 27, 2003
    Publication date: November 2, 2006
    Applicant: BAYER HEALTHCARE AG
    Inventors: Jens-Kerim Ergüden, Peter Kolkhof, Julio Castro-Palomino, Alexander Kuhl, Raimund Kast, Johannes-Peter Stasch, Hanna Tinel, Klaus Münter, Klemens Lustig, Josef Pernerstorfer, Martin Bechem, Jörg Hüser
  • Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and the use of the same as selective ligands of the adenosine receptor
    Patent number: 7129255
    Abstract: This application relates to compounds of the formula wherein the groups R1–R6 are as defined in the specification and claims, and to a pharmaceutical composition containing the same, and to a method of using the same in treatment of cardiovascular disorders.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: October 31, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Rosentreter, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Nicole Diedrichs, Thomas Krahn, Klaus Dembowsky, Johannes-Peter Stasch, Mitsuyuki Shimada
  • Heteroaryloxy-substituted phenylaminopyrimidines as rho-kinase inhibitors
    Publication number: 20060241127
    Abstract: The invention relates to heteroaryloxy-substituted phenylaminopyrimidines, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular diseases. The inventive compounds inhibit Rho-Kinase.
    Type: Application
    Filed: October 16, 2003
    Publication date: October 26, 2006
    Applicant: BAYER HEALTHCARE AG
    Inventors: Achim Feurer, Samir Bennabi, Heike Heckroth, Hartmut Schirok, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Jean Gnoth, Klaus Munter, Dieter Lang, Santiago Perez, Heimo Ehmke
  • Sulfonamide-substituted pyrazolopyridine compounds
    Patent number: 7115599
    Abstract: This invention relates to compounds of the formula in which R1, R2, and R3 are as defined in the claims, to a process for preparing such compounds, to pharmaceutical compositions containing such compounds, and to methods of using such compounds for treatment of hypertension and sexual dysfunction.
    Type: Grant
    Filed: November 12, 2001
    Date of Patent: October 3, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elisabeth Perzborn
  • Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and the use of the same
    Publication number: 20060217373
    Abstract: Compounds of the formula (I) a process for their preparation and their use as medicaments are described.
    Type: Application
    Filed: May 30, 2006
    Publication date: September 28, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Ulrich Rosentreter, Thomas Kramer, Mitsuyuki Shimada, Walter Hubsch, Nicole Diedrichs, Thomas Krahn, Kerstin Henninger, Johannes-Peter Stasch, Ralf Wischnat
  • Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and the use of the same
    Patent number: 7109218
    Abstract: Compounds of the formula (I) a process for their preparation and their use as medicaments are described.
    Type: Grant
    Filed: November 28, 2002
    Date of Patent: September 19, 2006
    Assignee: Bayer HealthCare AG
    Inventors: Ulrich Rosentreter, Thomas Krämer, Mitsuyuki Shimada, Walter Hübsch, Nicole Diedrichs, Thomas Krahn, Kerstin Henninger, Johannes-Peter Stasch, Ralf Wischnat
  • Carbamate-substituted pyrazolopyridine-derivatives
    Patent number: 7105523
    Abstract: This invention relates to compounds of the formula wherein R1 is H or a di-C1-6-alkylaminocarbonyl raical, and R2 is a radical of the formula —O—C(X)—NR3R4 wherein X is O or S. A process for preparing such compounds, pharmaceutical compositions containing them, and methods for using them in treatment of hypertension are also disclosed and claimed.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: September 12, 2006
    Assignee: Bayer Aktiengeselischaft
    Inventors: Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elisabeth Perzborn
  • 2,5-disubstituted pyrimidine derivatives
    Patent number: 7091198
    Abstract: The present invention relates to novel 2,5-disubstituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: August 15, 2006
    Assignee: Bayer HealthCare AG
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard König, Johannes-Peter Stasch, Elke Stahl, Rudy Schreiber, Frank Wunder
  • Derivatives of dicarboxylic acid having pharmaceutical properties
    Patent number: 7087644
    Abstract: The invention relates to compounds of formula (I) as well as the salts and stereoisomers thereof wherein the several variable groups are as defined in the specification and claims. Processes for making these materials, pharmaceutical compositions containing them, and methods for using them for treatment of cardiovascular disorders are also disclosed and claimed.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: August 8, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Cristina Alonso-Alija, Markus Heil, Dietmar Flubacher, Paul Naab, Josef Pernerstorfer, Johannes-Peter Stasch, Frank Wunder, Klaus Dembowsky, Elisabeth Perzborn, Elke Stahl
  • 2,5-DISUBSTITUTED PYRIMIDINE DERIVATIVES
    Publication number: 20060167016
    Abstract: The present invention relates to novel 2,5-disubstituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.
    Type: Application
    Filed: July 7, 2003
    Publication date: July 27, 2006
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard Konig, Johannes-Peter Stasch, Elke Stahl, Rudy Schreiber, Frank Wunder
  • Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines with adenosine receptor-binding activity and their use as cardiovascular preparations
    Patent number: 7078417
    Abstract: This application relates to pyridine derivatives having the general structure in which the several variables are as defined in the specification and claims, and to a process for preparing these compounds, a pharmacutical composition containing such compounds, and a method for using these materials for treatment of stable and unstable angina pectoris and atrial fibrillation.
    Type: Grant
    Filed: March 19, 2002
    Date of Patent: July 18, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Rosentreter, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Nicole Diedrichs, Thomas Krahn, Klaus Dembowsky, Johannes-Peter Stasch, Mitsuyuki Shimada
  • Adenosine receptor selective modulators
    Publication number: 20060154969
    Abstract: The invention relates to the compounds of formula (I), to a method for producing the same and to the use thereof as medicaments.
    Type: Application
    Filed: February 28, 2002
    Publication date: July 13, 2006
    Inventors: Ulrich Rosentreter, Thomas Kramer, Andrea Vaupel, Walter Hubsch, Nicole Diedrichs, Thomas Krahn, Klaus Dembowsky, Johannes-Peter Stasch
  • Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases
    Patent number: 7067694
    Abstract: Compounds of the general formula (I) wherein R1 represents halogen, R2 and R3 represent H or halogen, and R4 represents C3-8-cycloalkyl or optionally substituted phenyl, pharamceutical compositions containing such materials, and methods of using such materials in the treatment of various diseases are disclosed and claimed.
    Type: Grant
    Filed: February 18, 2002
    Date of Patent: June 27, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Härter, Michael G. Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Morpoline-bridged indazole derivatives
    Publication number: 20060128700
    Abstract: The present invention relates to novel morpholine-bridged indazole derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of disorders of the central nervous system.
    Type: Application
    Filed: September 16, 2003
    Publication date: June 15, 2006
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard Konig, Johannes-Peter Stasch, Frank Wunder, Dieter Lang, Elke Stahl, Thomas Schenke, Rudy Schreiber
  • Novel halogen-substituted aminodicarboxylic acid derivatives
    Publication number: 20060111444
    Abstract: This invention relates to methods for treating cardiovascular disorders selected from heart failure, thromboembolic disorders, venous diseases, and fibriotic disorders other than fibrosis of the liver, comprising administering an effective amount of a compound of formula (I) wherein the several variables are as defined in the specification and claims.
    Type: Application
    Filed: August 22, 2005
    Publication date: May 25, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Michael Harter, Michael Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
  • Substituted 2-thio-3, 5-dicyano-4-phenyl-6-aminopyridines and their use as adenosine receptor-selective ligands
    Patent number: 7045631
    Abstract: Compounds of the formula (I) a process for preparing them, and their use as medicaments are described.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: May 16, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Rosentreter, Thomas Kramer, Mitsuyuki Shimada, Walter Hubsch, Nicole Diedrichs, Thomas Krahn, Kerstin Henninger, Johannes-Peter Stasch
  • Substituted 2,5-diamidoindoles as ECE inhibitors for the treatment of cardiovascular diseases
    Patent number: 7045544
    Abstract: The invention relates to compounds of formula (I), to a method for the production thereof, and to the use of the same as pharmaceuticals for the treatment of diseases in humans and/or animals
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: May 16, 2006
    Assignee: Bayer HealthCare AG
    Inventors: Jens-Kerim Ergüden, Thomas Krahn, Christian Schröder, Johannes-Peter Stasch, Stefan Weigand, Hanno Wild, Michael Brands
  • Novel aminodicarboxylic acid derivatives having pharmaceutical properties
    Publication number: 20060094769
    Abstract: The invention relates to compounds of formulae (II), (IV), and (VI) as shown below, wherein the several variable groups are as defined in the specification and claims. Processes for making these materials, and methods for using them in the synthesis of compounds for treatment of cardiovascular disorders and fibrotic disorders are also disclosed.
    Type: Application
    Filed: August 8, 2005
    Publication date: May 4, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Cristina Alonso-Alija, Markus Heil, Dietmar Flubacher, Paul Naab, Josef Pernerstorfer, Johannes-Peter Stasch, Frank Wunder, Klaus Dembowsky, Elizabeth Perzborn, Elke Stahl
  • Carbamate-substituted pyrazolopyridines
    Publication number: 20060052397
    Abstract: The present invention relates to compounds which stimulate soluble guanylate cyclase, to the preparation thereof and to the use thereof as medicaments, in particular as medicaments for the treatment of cardiovascular disorders and/or sexual dysfunction.
    Type: Application
    Filed: April 25, 2003
    Publication date: March 9, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Cristina Alonso-Alija, Erwin Bischoff, Klaus Munter, Johannes-Peter Stasch, Elke Stahl, Stefan Weigand, Achim Feurer
  • 4-amino-substituted pyrimidine derivatives
    Publication number: 20060014951
    Abstract: The present invention relates to novel 4-amino-substituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.
    Type: Application
    Filed: July 7, 2003
    Publication date: January 19, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard Konig, Johannes-Peter Stasch, Elke Stahl, Rudy Schreiber, Frank Wunder, Dieter Lang