Abstract: Systems and methods for evenly heating a drum dryer of a print system. In one embodiment, the dryer is configured to rotate about an axis oriented in a lateral direction, to receive a radiant energy source disposed inside the drum that extends between each lateral end of the drum in the lateral direction, and to receive a reflective assembly inside the drum that includes an inner portion and an outer portion. The inner portion surrounds the radiant energy source and removably attaches the reflective assembly to a lateral end of the drum. The outer portion extends from the inner portion in a radial direction of the drum that is perpendicular to the lateral direction. The outer portion includes a reflective surface that reflects radiant energy from the lateral end to the central portion of the drum in contact with the web.

Abstract: A container system is disclosed, where the container system includes a housing. A chromatography cartridge is disposed in the housing. A structural support in the housing is configured to retain the chromatography cartridge within the housing. The housing is configured to withstand a certain amount of pressure generated inside the chromatography cartridge. The chromatography cartridge is disposed in the housing either in horizontal or in vertical position.

Abstract: A cognitive load reducing platform comprises one or more sensors that collect information about an environment as sensor data. A processor is in communication with the one or more sensors, wherein the processor executes a cognitive enhancement engines that processes the sensor data into enhanced characterization data having a reduced amount of data compared to the sensor data. An output device electronically communicate the enhanced characterization data to a user such that the enhanced characterization data reduces the cognitive load of the user, wherein the sensor and the output device comprise an assisted perception module worn by the user during an incident. A command interface device remote from the user to enable a person of authority to manage the incident and the user by receiving and displaying the enhanced characterization data, and by transmitting data and commands back to the assisted perception module.

Abstract: The present invention provides dosing regimens of anti-C5 antibodies, such as pozelimab, for treating or preventing C5-associated diseases such as paroxysmal nocturnal hemoglobinuria or CHAPLE disease.

Abstract: Enhancing edges of objects in a thermal image comprises receiving a thermal image and generating a gradient magnitude image comprising a plurality of pixels having associated gradient magnitude values. The gradient magnitude image is partitioned into subregions and gradient magnitude statistics are calculated for each. Mapping parameters are calculated for each of the subregions that equalize and smooth a dynamic range of the corresponding gradient magnitude statistics across the subregions. The mapping parameters calculated for each of the subregions are applied to pixels in the subregions to generate enhanced gradient magnitude values having equalized luminosity and contrast, and a wireframe image is formed therefrom having enhanced edges of objects. The wireframe image is displayed on a display device, wherein the wireframe image appears as a decluttered line drawing where the enhanced edges have increased luminosity and contrast compared to the thermal image to reduce the cognitive load of the user.

Abstract: An aspect a bit selection path configured to propagate a bit selection signal. The bit selection path includes bit selection delay circuitry defining a bit selection delay. The memory array includes a row selection path configured to propagate a row selection signal. The row selection path includes row selection delay circuitry defining a row selection delay. The memory array includes local selection circuitry. The local selection circuitry is configured to receive the bit selection signal from the bit selection path before the row selection signal from the row selection path according to the bit selection delay and the row selection delay.

Abstract: A technique relates to computer artifacts in a computer system. The technique includes creating a list of insights from artifacts, determining a similarity level between the insights of the artifacts and a predefined area of capability, comparing similarity level of insights for each of the artifacts to a threshold metric, removing artifacts having the similarity level below threshold metric such that artifacts remaining meet the threshold metric, and performing a pair-wise similarity comparison on the artifacts remaining which compares insights of the artifacts to each other to determine which ones are least common. The technique includes creating feature vectors for artifacts that are least common, determining a feature vector having a most variation in feature vectors, an artifact associated with the feature vector being determined to comprise a unique insight, and generating a unique message using the artifact associated with the feature vector being the unique insight.

Abstract: The present invention is a vehicle or trailer anti-theft device including electro-mechanical means and a temporary electrical power supply. The temporary electrical power supply acts momentarily upon the electro-mechanical device, thereby causing it to move into an activated condition. In its activated condition, it acts upon either on at least one wheel of the trailer, or the vehicle's parking brake system, to lock the at least one wheel, and remains in its activated condition without the need for any external power supply until such time as the electro-mechanical device is activated or re-connected to the temporary electrical power supply whereby the power supply is able to act momentarily upon the electro-mechanical device, and return said device to its deactivated condition, thereby causing the at least one wheel to be unlocked or the vehicle park brake to deactivate.

Abstract: An aspect a bit selection path configured to propagate a bit selection signal. The bit selection path includes bit selection delay circuitry defining a bit selection delay. The memory array includes a row selection path configured to propagate a row selection signal. The row selection path includes row selection delay circuitry defining a row selection delay. The memory array includes local selection circuitry. The local selection circuitry is configured to receive the bit selection signal from the bit selection path before the row selection signal from the row selection path according the bit selection delay and the row selection delay.

Abstract: Embodiments of the present invention are directed to methods, systems, and circuitry for reduced error in power consumption estimation for distinct circuitries. A non-limiting example includes distinct circuitry having an optimized power consumption definition. The distinct circuitry includes a substrate. The distinct circuitry includes an arrangement of interoperable hardware components disposed on the substrate having input pins defined according to a model described by a hardware description language operable to emulate toggle events of the interoperable hardware components defined by the model having a toggle event count based on combinations of the toggle events that correspond to predetermined power quantities. The toggle events define an aggregate toggle power consumption closer to an actual power consumption than an aggregate pin power consumption based on the input pins.

Abstract: A method of applying a data format in a direct memory access transfer is provided. The method includes distributing user data throughout a plurality of storage nodes through erasure coding, wherein the plurality of storage nodes are housed within a single chassis that couples the storage nodes as a cluster, each of the plurality of storage nodes having nonvolatile solid-state memory for user data storage. The method includes reading a self-describing data portion from a first memory of the nonvolatile solid-state memory and extracting a destination from the self-describing data portion. The method includes writing data, from the self-describing data portion, to a second memory of the nonvolatile solid-state memory according to the destination.

Abstract: A method for testing a circuit includes receiving, by a noise injection circuit, an input signal and generating a noise pulse. Generating the noise pulse includes computing an input resistor pulse, and computing an output resistor pulse. Generating the noise pulse further includes short-circuiting an output resistor substantially simultaneously with opening an input resistor. The method for testing the circuit includes modifying, by the noise injection circuit, the input signal using the noise pulse.

Abstract: A method of averting opioid addiction in a patient is disclosed. The method can be applied to a patient suffering from moderate to severe low back pain (LBP). The method comprises: diagnosing the patient as suffering from low back; administering to the patient a pharmaceutical composition comprising a therapeutically effective amount of an antibody that binds specifically to nerve growth factor (NGF) or an antigen binding fragment thereof; and avoiding administration of an opioid to the patient, and thereby relieving pain, and averting opioid addiction in a patient.

Abstract: An assisted perception (AP) module comprises an attachment mechanism to attach the AP module to a helmet, and a housing to integrate modular components of the AP module. The housing comprises a front portion and side portion, the front portion located over an eye of the user. The modular components include sensors to collect information about an environment as sensor data, and processors located in the side portion. The processors execute one or more assisted perception engines that process the sensor data from the sensors into enhanced characterization data. Output devices electronically communicate the enhanced characterization data to a user, wherein at least one of the output devices protrudes from the front portion of the housing in front of an eye of the user.

Abstract: The disclosure relates to the field of lymphedema therapy, more specifically, to a new pharmacological strategy to rescue the failed lymph pump system that can supplement, enhance or replace current therapies.

Abstract: Methods for treating moderate-to-severe or severe atopic dermatitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.

Abstract: A storage cluster includes a plurality of storage nodes. Each of the plurality of storage nodes includes nonvolatile solid-state memory and each of the plurality of storage nodes is configured to cooperate with others of the plurality of storage nodes having differing storage capacities in applying erasure coding. The plurality of storage nodes are configured to distribute the user data and metadata throughout the plurality of storage nodes.

Abstract: Intervertebral devices and systems, and methods of their use, are disclosed having configurations suitable for placement between two adjacent vertebrae, replacing the functionality of the disc therebetween. Intervertebral devices and systems contemplated herein are implantable devices intended for replacement of a vertebral disc, which may have deteriorated due to disease for example. The intervertebral devices and systems are configured to allow for ample placement of therapeutic agents therein, including bone growth enhancement material, which may lead to better fusion between adjacent vertebral bones. The intervertebral devices and systems are configured for use in minimally invasive procedures, if desired.

Abstract: Enhancing edges of objects in a thermal image comprises receiving a thermal image and generating a gradient magnitude image comprising a plurality of pixels having associated gradient magnitude values. The gradient magnitude image is partitioned into subregions and gradient magnitude statistics are calculated for each. Mapping parameters are calculated for each of the subregions that equalize and smooth a dynamic range of the corresponding gradient magnitude statistics across the subregions. The mapping parameters calculated for each of the subregions are applied to pixels in the subregions to generate enhanced gradient magnitude values having equalized luminosity and contrast, and a wireframe image is formed therefrom having enhanced edges of objects. The wireframe image is displayed on a display device, wherein the wireframe image appears as a decluttered line drawing where the enhanced edges have increased luminosity and contrast compared to the thermal image to reduce the cognitive load of the user.