Abstract: Improved iminium based processes for the production of cyanoacrylates and methylidene malonates wherein the improvement pertains to the presence of acid chlorides and/or acid anhydrides in the reaction mix.

Abstract: The embodiments herein are directed to a reusable frameless vehicle roof-top carrier configured, dimensioned and arranged to securely mount and carry cargo loads having a size and shape similar to cut evergreen trees, while protecting the vehicle finish and cargo from damage. The reusable vehicle roof-top carrier is trapezoidal shaped to conveniently bind and condense branches of the tree, while catching sap drippings. Illustratively, the vehicle roof-top carrier is made from a tear-resistant fabric and includes a non-tacky non-slip surface placed in slip-resistant contact with the roof of the vehicle so as to prevent slippage (i.e., movement) of the tree during transport.

Abstract: An ion generating device can include a housing having an opening, an anode and a cathode disposed within the housing and having a space between them in fluid communication with the opening, a power source having a negative terminal and a positive terminal with a first connection between the negative terminal and the anode and a second connection between the positive terminal and the cathode, and an air mover disposed to direct an air flow through the space and out of the opening.

Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.

Abstract: The present invention relates to new methods of selecting and breeding organisms, in particular organisms which exhibit symbiotic behaviour with symbionts, and to new organisms and symbiota developed thereby, such as plant or grass and endophyte symbiota. Multiple symbionts are deployed in multiple organisms and selected for improved symbiotic compatibility and performance early in the breeding process. Methods include producing improved organisms from germplasm, by inoculating host organism germplasm libraries with symbionts selected from symbiont libraries and selecting improved host organisms exhibiting desired symbiota characteristics, and selection of organism-symbiont associations with a desired genetic and metabolic profile by metagenomic analysis of nucleic acid libraries from an organism or organism-symbiont association.

Abstract: A method is presented for organizing and carrying out a training program, a seminar or a workshop having a plurality of participants to assist each participant in improving an efficiency and function of a business organization to which that participant belongs. The method exposes the participants to structures and regulations utilized for maintaining proper function of a deployed submarine having a plurality of crew members. Each crew member is subjected to a check-in procedure and required to assume ownership of a role. Each crew member must qualify to perform a function associated with the assumed role and each crew member has an assigned ombudsman. The training procedure then equates members of the business organization to which a participant belongs to those crew members. The invention has the advantage of improving performance elements dependent on factors which are of evident importance in a submarine environment but whose central relevance normally remains unnoticed in a normal business organization.

Abstract: A bearing assembly for an electrical generator includes a frame, a bearing liner, a bearing and a non-metallic ring. The frame is configured to connect with a housing of the electrical generator. The bearing liner is connected with the frame. The bearing is received in the bearing liner. The non-metallic ring is interposed between the bearing liner and the bearing.

Abstract: A chair has a seat portion and a leg portion. The seat portion and the leg portion are joined by a structure that allows that seat portion to wobble relative to the leg portion. The structure can include one or more resilient member to create the wobble and one or more motion restrictor member to limit the amount of wobble or prevent wobble.

Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-?-hydroxysteroids from ?-9,11-ene, 11-keto or 11-hydroxy-?-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.

Abstract: Improved iminium based processes for the production of cyanoacrylates and methylidene malonates wherein the improvement pertains to the presence of acid chlorides and/or acid anhydrides in the reaction mix.

Abstract: A grasp management system and corresponding methods are described. In some examples, information about a set of grasps of a robotic manipulator is accessed. The information is used by the robotic manipulator to attempt to grasp an item using the set of grasps associated with a first grasping orientation. An orientation of the robotic manipulator can be adjusted into a second grasping orientation and the robotic manipulator can attempt to grasp the item using the set of grasps associated with the second grasping orientation. Information about the attempts can be recorded and used to determine a richness measure that may represent a richness of the set of grasps for the item.

Abstract: A bearing assembly for an electrical generator includes a frame, a bearing liner and a ring. The frame is configured to connect with a housing of an electrical generator. The frame includes a frame opening and is made from a first material. The bearing liner connects with the frame. The bearing liner is made from a second material, which is dissimilar from the first material. At least a portion of the bearing liner passes through the frame opening. The ring surrounds the bearing liner. The ring contacts the frame and the bearing liner and maintains a clearance between the portion of the bearing liner passing through the frame opening and the frame.

Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-?-hydroxysteroids from ?-9,11-ene, 11-keto or 11-hydroxy-?-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.

Abstract: Compounds are provided according to Formula (I), and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein A, R1, and R5 are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

Abstract: In an embodiment, therapeutic methods and uses of Bruton's Tyrosine Kinase (BTK) inhibitors for treatment of cancer, inflammation, immune disorders, and autoimmune disorders, including dermatoses, and for transplantation prophylaxis, based on BTK occupancies and/or BTK resynthesis rates for B cells in various diseases, tissue compartments, including bone marrow and lymph nodes, are described. In an embodiment, dosing regimens for a BTK inhibitor for treatment of cancer, inflammation, immune disorders, and autoimmune disorders, including dermatoses, and for transplantation prophylaxis, based on BTK occupancies and/or BTK resynthesis rates for B cells in various diseases, tissue compartments, including bone marrow and lymph nodes, are described.

Abstract: A rotating machine includes a housing and a first bearing received in the housing. The rotating machine also includes a shaft supported by the first bearing. The shaft defines a central axis that extends in a longitudinal direction. The rotating machine also includes at least one duct radially interior to the outer diameter of the shaft. The duct includes an inlet port and a radial outlet port that are in fluid communication with one another. The inlet port is configured to receive air and the radial outlet port is configured to discharge the air. The rotating machine also includes an air mover longitudinally disposed between the first bearing and the inlet port of the duct. The air mover creates an area of air pressure at the radial outlet port that is less than an air pressure at the inlet port.

Abstract: Methods, apparatus, systems and articles of manufacture (e.g., physical storage media) to reroute tunnel traffic in a network are disclosed. Example methods disclosed herein include, in response to detecting an event associated with routing first traffic in the network, determining a plurality of paths to carry respective traffic for a plurality of tunnels between pairs of routers in the network, the plurality of paths being determined based on a quality metric characterizing an aggregate tunnel bandwidth to be carried by the plurality of paths for the plurality of tunnels. Such disclosed example methods also include sending first routing information describing the plurality of paths to the routers in the network to cause the routers to route the respective traffic for the plurality of tunnels using the plurality of paths.

Abstract: A transfer rack on one floor of an inventory system can receive multiple containers each carrying an inventory item designated for an operation on a different floor of the inventory system. A vertical lift can move the transfer rack carrying the multiple containers from the one floor to the different floor. On the different floor, the multiple containers may be swapped for different multiple containers each carrying an inventory item designated for an operation on the one floor. The vertical lift may return the transfer rack carrying the different multiple containers to the one floor.

Abstract: Various aspects provide for managing data associated with a cache memory. For example, a system can include a cache memory and a memory controller. The cache memory stores data. The memory controller maintains a history profile for the data stored in the cache memory. In an implementation, the memory controller includes a filter component, a tagging component and a data management component. The filter component determines whether the data is previously stored in the cache memory based on a filter associated with a probabilistic data structure. The tagging component tags the data as recurrent data in response to a determination by the filter component that the data is previously stored in the cache memory. The data management component retains the data in the cache memory in response to the tagging of the data as the recurrent data.

Abstract: Various aspects provide for mitigating voltage droop associated with a microprocessor (e.g., by controlling a clock associated with the microprocessor). For example, a system can include a microprocessor and a controller. The microprocessor can receive a clock provided by a clock buffer. The controller can control frequency of the clock provided by the clock buffer based on a voltage associated with the microprocessor. In an aspect, the controller can reduce the frequency of the clock in response to a determination that the voltage satisfies a defined criterion. Additionally, the controller can incrementally increase the frequency of the clock in response to another determination that the voltage satisfies another defined criterion after satisfying the defined criterion.