Abstract: A stent may be actuatable between a delivery configuration and a deployed configuration. A stent may include one or more interwoven filaments each including a cross-sectional profile having at least one flattened portion. A flattened portion of a first filament portion of the one or more filaments may be positioned in contact with a flattened portion of a second filament portion of the one or more filaments.

Abstract: The present disclosure relates to the field of weight loss. Specifically, the present disclosure relates to systems and methods for reducing daily caloric loads by limiting the delivery of long chain fatty acids into the bloodstream. More specifically, the present disclosure relates to systems and methods for reducing or restricting the flow of chylomicron lipids from the cysterna chyli through the thoracic duct into the bloodstream.

Abstract: This disclosure concerns systems and methods for tissue resection. Systems according to the various embodiments of the invention include cutting instruments, particularly laser cutting heads, and/or polymer materials that form polymer bodies when flowed into tissue.

Abstract: The present disclosure relates to the field of endoscopy. Specifically, the present disclosure relates to systems and methods for en bloc resection of malignant and pre-malignant lesions and/or tumors within the gastrointestinal (GI) tract. More specifically, the present disclosure relates to systems and methods for delivering an expandable scaffold between tissue layers (e.g., between the muscularis and submucosa layers) to elevate and stabilize the lesion or tumor for fast and efficient resection.

Abstract: This disclosure concerns magnetic or electromagnetic systems and methods for tissue resection. Systems according to the various embodiments of the disclosure include a first component such as a thin plate or a plurality of beads which, in either case, include magnetic materials and are sized to be inserted between mucosal and submucosal tissue layers, and a second component that may be used to apply an attractive (e.g. magnetic) force to the first component.

Abstract: A reduced absorption device may include a proximal anchor and a distal sleeve including a frame and a membrane. The membrane may include a plurality of porous regions, and each porous region may be configured to align with a corresponding region of an intestine configured to absorb nutrients.

Abstract: An endoscopic stent for implantation in a patient after sleeve gastrectomy or biliopancreatic diversion with duodenal switch or biliopancreatic diversion with duodenal switch comprising a stent portion, the stent portion comprising a proximal end portion, the proximal end portion defined by a length of about 50 mm to about 200 mm, an enlarged middle portion, a middle portion having an enlarged diameter relative to the proximal end portion and the distal end portion and defined by a length of about 20 mm to about 80 mm, and a distal end portion and a polymeric sleeve portion engaged to and extending distally from the distal end portion of the stent.

Abstract: A system for restricting a stomach of a patient may include a plurality of discrete magnetic devices. Each magnetic device may include a magnet and be configured to be secured to tissue. A first portion of the plurality of magnetic devices may be configured to be transorally inserted into the patient and secured to a first wall of the stomach, and a second portion of the plurality of magnetic devices may be configured to be transorally inserted into the patient and secured to a second wall of the stomach. The first and second portions may be configured to be magnetically joined together to draw the first and second walls of the stomach towards each other.

Abstract: This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes a stent having a first strut. The first strut may include an inner surface and an outer surface. The medical device may also include a first attachment member coupled to the strut and a radioactive element. The radioactive element may be coupled to the attachment member.

Abstract: An endoscopic stent for implantation in a patient after sleeve gastrectomy or biliopancreatic diversion with duodenal switch or biliopancreatic diversion with duodenal switch comprising a stent portion, the stent portion comprising a proximal end portion, the proximal end portion defined by a length of about 50 mm to about 200 mm, an enlarged middle portion, a middle portion having an enlarged diameter relative to the proximal end portion and the distal end portion and defined by a length of about 20 mm to about 80 mm, and a distal end portion and a polymeric sleeve portion engaged to and extending distally from the distal end portion of the stent.

Abstract: This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes a stent having a plurality of longitudinally extending filaments. The stent also has an inner surface and an outer surface and a plurality of tubular members extending along the stent. Each of the plurality of tubular members is coupled with one or more of the plurality of longitudinally extending filaments and each of the plurality of tubular members is configured to accept a radioactive element, a spacer or both.

Abstract: This disclosure provides design, material, preparation methods, and use alternatives for medical devices. An example stent includes an expandable framework and a plurality of tubular members disposed along the expandable framework. Each of the plurality of tubular members include a lumen extending therein. The example stent also include a coating, wherein the coating is applied directly to both the plurality of tubular members and the expandable framework.

Abstract: This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes a scaffold including a central member and a plurality of extension members extending away from the central member. The central member includes a plurality of discrete attachment locations corresponding to each of the plurality of extension members and each of the plurality of extension members is pivotably coupled to the central member at a corresponding discrete attachment location. The medical device also includes a covering substantially surrounding the scaffold and an electrode located at a distal end of each of the plurality of extension members. Each electrode extends through at least a portion of the covering.

Abstract: Methods, devices, and systems for obtaining a navigating to a targeted biopsy region are disclosed. An example device for navigating to a targeted biopsy region may include an elongate shaft having a proximal end, a distal end, an inflation lumen, and a vacuum lumen. An inflatable balloon may be positioned proximal to the distal end of the elongate shaft. The device may further include an ultrasound transducer positioned adjacent to the distal end of the elongate shaft and a power and control unit in electrical communication with the ultrasound transducer. A vacuum source may be in fluid communication with the vacuum lumen.

Abstract: Methods and devices for dilating a stricture of a body lumen are disclosed. In some embodiments, a device for dilating a lumen of a body comprises an elongate member having a proximal end and a distal end and an inflatable scaffold member disposed on the distal end of the elongate member, the inflatable scaffold member defining a lumen. In some additional embodiments, the device may further include an inflation member in fluid communication with the lumen of the inflatable scaffold member. Additionally, in some embodiments, the inflatable scaffold member is frangibly connected to the inflation member.

Abstract: An implantable medical device for implantation within a passageway of a patient comprises a stent including a plurality of wires, at least one of the plurality of wires having a cross-section having a first tapered point, and a covering layer having an inner diameter and an outer diameter. In some embodiments, the plurality of wires may be disposed at least partially around the covering layer. Additionally in some embodiments, the first tapered point may extend outward further than the outer diameter of the covering layer.

Abstract: An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member may include at least one flexible tie affixed to an end thereof. The tie may allow the stent to be attached to a lumen wall with a clip, such as a retention clip, to inhibit migration of the stent within the body lumen.

Abstract: A needle for collecting a tissue sample includes a needle body extending longitudinally from a proximal end to a distal end and including a channel extending therethrough and a plurality of optical fibers extending along a length of the needle body and configured to pass laser energy therethrough to the distal end of the needle body to cut and collect a tissue sample within the channel.

Abstract: A tubular prosthesis that includes a scaffolding formed by at least one scaffolding filament; a cover; and at least one controlled ingrowth feature constructed and arranged to abut an inner surface of a lumen wall when the prosthesis is implanted in the body lumen. The controlled ingrowth feature may extend inwards or outwards from the prosthesis outer surface. The controlled ingrowth feature may be formed by a scaffolding filament; by a separate filament; by the cover; and combinations thereof.

Abstract: A prosthesis that when implanted in the gastrointestinal tract does not impede the normal function of the pyloric sphincter. In some instances, the prosthesis is implanted as part of, or after, a sleeve gastrectomy procedure. The prosthesis includes a stent with an outer surface and a polymeric cover fully covering the outer surface of the stent. The stent includes a proximal stent flange; a proximal stent segment extending distally from the proximal stent flange; and an enlarged stent segment extending distally from the proximal stent segment.