Patents by Inventor John A. Kessler

John A. Kessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8796022
    Abstract: The present invention provides method, compositions, and systems for generating basal forebrain cholinergic neurons (BFCNs) using FGF8, SHH, LXH8, GBX1, or vectors encoding these ligands, as well as using such BFCNs to treat neurological disorders such as Alzheimer's disease.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: August 5, 2014
    Assignee: Northwestern University
    Inventors: Christopher Bissonnette, John Kessler
  • Patent number: 8697048
    Abstract: The present invention relates to the use of self-assembling peptide amphiphiles to prevent tumor formation by transplanted stem cells. The present invention further relates to the use of self-assembling peptide amphiphiles to treat cancers.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: April 15, 2014
    Assignee: Northwestern University
    Inventors: Li-Ru Zhao, John A. Kessler
  • Publication number: 20140041309
    Abstract: An air and/or debris dam for moving coil balance assembly for a hung window is disclosed. The air and/or debris dam is located between the carrier and a mounting location of a moving coil window balance assembly. The air and/or debris dam can travel within the jamb channel of a window frame assembly to inhibit airflow and/or the deposition of dust and/or debris in the jamb channel.
    Type: Application
    Filed: August 9, 2013
    Publication date: February 13, 2014
    Applicant: Caldwell Manufacturing Company North America, LLC
    Inventors: Jay Sofianek, Wilbur James Kellum, III, John Kessler
  • Publication number: 20140007809
    Abstract: An in-line production apparatus and a method for composition control of copper indium gallium diselenide (CIGS) solar cells fabricated by a co-evaporation deposition process. The deposition conditions are so that a deposited Cu-excessive overall composition is transformed into to a Cu-deficient overall composition, the final CIGS film. Substrates with a molybdenum layer move through the process chamber with constant speed. The transition from copper rich to copper deficient composition on a substrate is detected by using sensors which detect a physical parameter related to the transition. Preferred embodiment sensors are provided that detect the composition of elements in the deposited layer. A controller connected to the sensors adjusts the fluxes from the evaporant sources in order provide a CIGS layer with uniform composition and thickness over the width of the substrate.
    Type: Application
    Filed: September 6, 2013
    Publication date: January 9, 2014
    Applicant: SOLIBRO RESEARCH AB
    Inventors: LARS STOLT, JOHN KESSLER
  • Patent number: 8524655
    Abstract: The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: September 3, 2013
    Assignee: Northwestern University
    Inventors: Li-Ru Zhao, John Kessler, Seema Singhal, Jayesh Mehta
  • Publication number: 20120237484
    Abstract: The present invention provides method, compositions, and systems for generating basal forebrain cholinergic neurons (BFCNs) using FGF8, SHH, LXH8, GBX1, or vectors encoding these ligands, as well as using such BFCNs to treat neurological disorders such as Alzheimer's disease.
    Type: Application
    Filed: July 8, 2011
    Publication date: September 20, 2012
    Inventors: Christopher Bissonnette, John Kessler
  • Publication number: 20120093784
    Abstract: The present invention relates to the use of self-assembling peptide amphiphiles to prevent tumor formation by transplanted stem cells. The present invention further relates to the use of self-assembling peptide amphiphiles to treat cancers.
    Type: Application
    Filed: December 21, 2011
    Publication date: April 19, 2012
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Li-Ru Zhao, John A. Kessler
  • Publication number: 20100286039
    Abstract: The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.
    Type: Application
    Filed: February 26, 2010
    Publication date: November 11, 2010
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Li-Ru Zhao, John Kessler, Seema Singhal, Jayesh Mehta
  • Publication number: 20100233841
    Abstract: Thin-film solar cells of the CIGS-type use two integrally formed buffer layers, a first ALD Zn(O,S) buffer layer on top of the CIGS-layer and a second ALD ZnO-buffer layer on top of the first buffer layer. Both buffer layers are deposited in the same process step using ALD (atom layer deposition). The technology also relates to a method of producing the cell and a process line for manufacturing of the cell structure.
    Type: Application
    Filed: May 27, 2010
    Publication date: September 16, 2010
    Applicant: SOLIBRO RESEARCH AB
    Inventors: Charlotte PLATZER BJĂ–RKMAN, John Kessler, Lars Stolt
  • Publication number: 20080254202
    Abstract: An in-line production apparatus and a method for composition control of copper indium gallium diselenide (CIGS) solar cells fabricated by a co-evaporation deposition process. The deposition conditions are so that a deposited Cu-excessive overall composition is transformed into to a Cu-deficient overall composition, the final CIGS film. Substrates with a molybdenum layer move through the process chamber with constant speed. The transition from copper rich to copper deficient composition on a substrate is detected by using sensors which detect a physical parameter related to the transition. A preferred embodiment sensors are provided that detect the composition of elements in the deposited layer. A controller connected to the sensors adjusts the fluxes from the evaporant sources in order provide a CIGS layer with uniform composition and thickness over the width of the substrate.
    Type: Application
    Filed: March 4, 2005
    Publication date: October 16, 2008
    Applicant: SOLIBRO AB
    Inventors: Lars Stolt, John Kessler
  • Publication number: 20070115129
    Abstract: Disclosed are deactivatable RFID labels and tags in individual and web form, and methods of making same. When it is desired to deactivate the label or tag, the tag or label is subjected to tearing. One arrangement involves providing the label or tag with a tear strip by which the RFID transponder in the label or tag is destroyed, and in another arrangement a tag can be torn along a weakening line to destroy the RFID transponder.
    Type: Application
    Filed: November 23, 2005
    Publication date: May 24, 2007
    Inventor: John Kessler
  • Publication number: 20060247165
    Abstract: The present invention relates to methods and compositions for altering (e.g., augmenting or stimulating) differentiation and growth of cells (e.g., neural progenitor cells and neurons). In particular, the present invention relates to compositions comprising one or more self-assembling peptide amphiphiles (e.g., in solution or that generate (e.g., self-assemble into) nanofibers (e.g., that are able to encapsulate cells and promote cellular differentiation (e.g., neurite development))) and methods of using the same. Compositions and methods of the present invention find use in research, clinical (e.g., therapeutic) and diagnostic settings.
    Type: Application
    Filed: January 23, 2006
    Publication date: November 2, 2006
    Inventors: Samuel Stupp, John Kessler
  • Publication number: 20060222430
    Abstract: A method and system operable in multiple modes of operation and including a web feeding mode and an idle mode. In the web feeding mode, the device operates to perform a function on a linerless web having tacky adhesive in contact with a feed roll by which the web is being moved or advanced. This function can be a printing function and/or an RFID and/or write function, or other functions. During the idle mode, the controller can cause the web feeding device to perform a cycling program to abate excessive sticking or bonding of the tacky linerless web to the feed roll.
    Type: Application
    Filed: April 1, 2005
    Publication date: October 5, 2006
    Inventors: Jeanne Duckett, John Kessler
  • Publication number: 20060180200
    Abstract: The present invention relates to thin-film solar cells of the CIGS-type. A characteristic feature of the invention is the use of two integrally formed buffer layers, a first ALD Zn(O,S) buffer layer (7) on top of the CIGS-layer (3) and a second ALD ZnO-buffer layer (8) on top of the first (7) buffer layer. Both buffer layers are deposited in the same process step using ALD (atom layer deposition). The invention also relates to a method of producing the cell and a process line for manufacturing of the cell structure.
    Type: Application
    Filed: May 5, 2004
    Publication date: August 17, 2006
    Inventors: Charlotte Platzer Bjorkman, John Kessler, lars Stoit
  • Publication number: 20060153799
    Abstract: The present invention relates to the use of stem cell factor (SCF) polypeptide, alone and in combination with granulocyte colony stimulating factor (G-CSF) polypeptide, in the prevention or treatment of injury to the brain after cerebral ischemia or neurological disorder. More particularly, the invention provides methods of improving neurological function and outcome after stroke by the administration of SCF polypeptide, alone and in combination with G-CSF polypeptide. This treatment can be used alone or in combination with other well-known methods of treatment of cerebral ischemia and neurological disorders in a mammal.
    Type: Application
    Filed: November 4, 2005
    Publication date: July 13, 2006
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Li-Ru Zhao, John Kessler, Seema Singhal, Mehta Jayesh
  • Publication number: 20060059668
    Abstract: The safety pin with an arcuate pin bar is formed from pin wire bent in the middle to form a coil having a stationary bar extending from one end of the coil and a pin bar with a pointed end extending from the opposite end of the coil. The pin bar is arcuate, or formed with an arch. The stationary bar has a shield attached thereto, the end of the stationary bar being bent backward or the shield being attached to the end of the stationary bar so that the shield extends at an angle complementary to the curvature of the pin bar. The stationary bar may have a textured or roughened fin formed thereon, and may have linear inner and outer edges, a straight inner edge and convex outer edge, or a concave inner edge and convex outer edge.
    Type: Application
    Filed: August 17, 2005
    Publication date: March 23, 2006
    Inventor: John Kessler
  • Publication number: 20050214257
    Abstract: The present invention relates to the use of self-assembling peptide amphiphiles to prevent tumor formation by transplanted stem cells. The present invention further relates to the use of self-assembling peptide amphiphiles to treat cancers.
    Type: Application
    Filed: December 21, 2004
    Publication date: September 29, 2005
    Applicant: Northwestern University
    Inventors: Li-Ru Zhao, John Kessler
  • Patent number: 6011004
    Abstract: This invention relates to the use of neuronotrophic factors, such as nerve growth factor (NGF), ciliary derived neuronotrophic factor (CNTF), brain derived neuronotrophic factor (BDNF), neuronotrophin-3 (NT-3), fibroblast growth factor (FGF), epidermal growth factor (EGF), transforming growth factor .alpha. (TFG-.alpha.), transforming growth factor .beta. (TGF-.beta.) and others to prevent drug-induced neuropathy.
    Type: Grant
    Filed: December 17, 1996
    Date of Patent: January 4, 2000
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: John A. Kessler, Stuart C. Apfel
  • Patent number: 5648335
    Abstract: The invention features a method of using insulin-like growth factor-I (IGF-I) or insulin-like growth factor-III (IGF-III) to prevent or treat peripheral neuropathy in a mammal.
    Type: Grant
    Filed: June 4, 1996
    Date of Patent: July 15, 1997
    Assignees: Cephalon, Inc., Albert Einstein College of Medicine of Yeshiva Univ.
    Inventors: Michael E. Lewis, Stuart C. Apfel, John A. Kessler
  • Patent number: 5633228
    Abstract: The invention features a method of using insulin-like growth factor-I (IGF-I) or insulin-like growth factor-III (IGF-III) to prevent or treat peripheral neuropathy in a mammal.
    Type: Grant
    Filed: December 29, 1994
    Date of Patent: May 27, 1997
    Assignees: Cephalon, Inc.,, Albert Einstein College of Medicine of Yeshiva University
    Inventors: Michael E. Lewis, Stuart C. Apfel, John A. Kessler