Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).

Abstract: Audio amplification may be improved by controlling an audio amplifier based on the audio signal being amplified. For example, when the audio signal level increases or decreases, a boost voltage provided to an audio amplifier by a boost converter may also be increased or decreased. In another example, when the audio signal level decrease below a certain level, the audio amplifier may be switched from amplifying the audio signal with a boost converter input to amplifying the audio signal with a low voltage input. Control of the audio amplifier may be implemented in a digital boost converter controller coupled to the boost converter and/or the audio amplifier.

Abstract: An intravenous baclofen solution is disclosed, along with methods of dosing and treatment therewith.

Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).

Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).

Abstract: Audio amplification may be improved by controlling an audio amplifier based on the audio signal being amplified. For example, when the audio signal level increases or decreases, a boost voltage provided to an audio amplifier by a boost converter may also be increased or decreased. In another example, when the audio signal level decrease below a certain level, the audio amplifier may be switched from amplifying the audio signal with a boost converter input to amplifying the audio signal with a low voltage input. Control of the audio amplifier may be implemented in a digital boost converter controller coupled to the boost converter and/or the audio amplifier.

Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).

Abstract: Existing telecommunications equipment may require network connectivity for data transfer but may have no external interfaces except for the TDM voice circuits to which they are connected. Thus on most newer systems, an additional local management interface is provided for proprietary maintenance functions. This is typically accessed via a shell-based Command Line Interface. This cannot be used on a remote site with only TDM connections.

Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases.

Abstract: A self-leveling mounting assembly for mounting a mountable object on a vertical surface is described. The assembly includes: an engagement member structurally integrated in or securable to a mountable object, and providing a cavity; a fixturing plate adapted for securement to a vertical surface; and a retention member coupleable with the fixturing plate and with the cavity of the engagement member. The retention member includes first and second portions that are rotatable in relation to one another, with the first portion being fixedly positioned in relation to the fixturing plate, and with the second portion being positioned in the cavity to allow self-leveling movement of the mountable object on the vertical surface.

Abstract: Compositions for delivering an active ingredient include particles comprising an active ingredient (for example, 1-MCP complex powder) imbedded in a resin matrix, the particles being suspended in an oil medium. Methods for preparing such compositions include blending an active ingredient with a resin at a temperature higher than the melting point of the resin to provide a blend; dispersing the blend into an oil medium at a temperature higher than the melting point of the resin to provide a dispersion comprising dispersed particles in the oil medium; and consolidating the dispersed particles to provide consolidated particles comprising a solid matrix of the resin impregnated with the active ingredient. Methods of using such compositions include mixing the compositions with an aqueous medium to provide an emulsion or slurry and either contacting plants or plant parts with the emulsion or placing the emulsion near plants or plant parts.

Abstract: There is provided a coating composition comprising (a) one or more microbicide, (b) one or more soluble polymer comprising acrylamide as polymerized units, wherein said polymer has is non-anionic, and (c) solvent, wherein said polymer is dissolved in said solvent. Also provided is a method of coating a substrate with such a coating, and also provided is the resulting coated substrate.

Abstract: There is provided a coating composition comprising (a) one or more microbicide, (b) one or more soluble polymer comprising acrylamide as polymerized units, wherein said polymer has is non-anionic, and (c) solvent, wherein said polymer is dissolved in said solvent. Also provided is a method of coating a substrate with such a coating, and also provided is the resulting coated substrate.

Abstract: Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases.

Abstract: A loader for inserting an ammunition cartridge into a gun's magazine includes a body operable to hold two or more ammunition cartridges, a retainer to prevent a cartridge held by the body from leaving the body and operable to release a held cartridge from the body to position the cartridge for insertion into a gun's magazine, and an insertion component to exert pressure on a positioned cartridge to insert the cartridge into the gun's magazine. When the loader is used to insert a cartridge into a gun's magazine, the insertion component extends into the gun's carrier opening, a cartridge from the body is positioned on the insertion component, and the body is then moved relative to the gun's magazine. By holding the cartridges with the body and forcing a positioned cartridge into the gun's magazine with the insertion component, one can quickly and efficiently load a gun's magazine.

Abstract: The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

Abstract: A loader for inserting an ammunition cartridge into a gun's magazine includes a body operable to hold two or more ammunition cartridges, a retainer to prevent a cartridge held by the body from leaving the body and operable to release a held cartridge from the body to position the cartridge for insertion into a gun's magazine, and an insertion component to exert pressure on a positioned cartridge to insert the cartridge into the gun's magazine. When the loader is used to insert a cartridge into a gun's magazine, the insertion component extends into the gun's carrier opening, a cartridge from the body is positioned on the insertion component, and the body is then moved relative to the gun's magazine. By holding the cartridges with the body and forcing a positioned cartridge into the gun's magazine with the insertion component, one can quickly and efficiently load a gun's magazine.

Abstract: This invention is directed to acylated amino acid amidyl pyrazoles and related compounds of Formula I. The invention is also directed to a pharmaceutical formation comprising such compound or in a pharmaceutically acceptable salt form thereof. The invention is further directed to a method for inhibiting ?-amyloid peptide release and/or synthesis, a method for inhibiting ?-secretase activity, and a method for treating neurological disorders associated with ?-amyloid peptide production. The method comprises administering to a host a pharmaceutical formulation comprising an effective amount of a compound of Formula I. The compounds of Formula I are useful in the prevention and treatment of Alzheimer's disease.

Abstract: This invention is directed to acylated amino acid amidyl pyrazoles and related compounds of Formula I. The invention is also directed to a pharmaceutical formation comprising such compound or in a pharmaceutically acceptable salt form thereof. The invention is further directed to a method for inhibiting ?-amyloid peptide release and/or synthesis, a method for inhibiting ?-secretase activity, and a method for treating neurological disorders associated with ?-amyloid peptide production. The method comprises administering to a host a pharmaceutical formulation comprising an effective amount of a compound of Formula I. The compounds of Formula I are useful in the prevention and treatment of Alzheimer's disease.

Abstract: Disclosed are compounds of the formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.