Abstract: A catheter insertion device is provided that includes an insertion needle that is retractable into the device after use to prevent exposure to the contaminated needle. The needle retainer releasably retains the needle in an extended position against the bias of the biasing element. When the catheter is removed from the insertion device, the needle retainer automatically releases the needle, which is propelled rearwardly into the device. A device for inserting a guide wire into a patient is also provided. The device includes an insertion needle that is retractable into the housing of the device after use. A needle retainer releasably retains the needle in an extended position against the bias of the biasing element. After the guide wire is inserted into the patient, the needle retainer allows the needle to be released, so that the needle is retracted into the device.

Abstract: Needle-bearing medical devices are provided for fluid infusion, fluid transfusion, and inserting a guide wire. After use the needle is shielded to render the contaminated needle safe to prevent inadvertent needle sticks. The device includes a housing and a needle having a sharpened tip. A biasing element biases the needle toward a position in which the sharpened tip is shielded.

Abstract: A device for injecting fluid from a pre-filled cartridge is provided. The device includes a needle for piercing a patient. After an injection, the needle can be retracted to prevent inadvertent contact with the contaminated needle. A needle retainer releasably retains the needle in the retracted position. The needle can subsequently be re-extended to administer a subsequent injection. After the cartridge is emptied, the cartridge can be removed, if desired, and replaced with another cartridge for additional injections. Alternatively, the needle can be substantially permanently retracted into the device and safely disposed of in a sharps container.

Abstract: A catheter insertion device is provided for inserting an over-the-needle catheter. The device includes an insertion needle that is retractable into the housing of the device after use to prevent exposure to the contaminated needle. A needle retainer releasably retains the needle in an extended position against the rearward bias of the biasing element. The needle retainer engages the hub of the catheter so that when the catheter is removed from the insertion device, the needle retainer automatically releases the needle. The biasing element then propels the needle rearwardly into the housing of the device. The device further allows the operator to intervene to delay retraction if desired.

Abstract: A device for injecting fluid from a pre-filled cartridge is provided. The device includes a needle for piercing a patient. After an injection, the needle can be retracted to prevent inadvertent contact with the contaminated needle. A needle retainer releasably retains the needle in the retracted position. The needle can subsequently be re-extended to administer a subsequent injection. After the cartridge is emptied, the cartridge can be removed, if desired, and replaced with another cartridge for additional injections. Alternatively, the needle can be substantially permanently retracted into the device and safely disposed of in a sharps container.

Abstract: The present invention relates to a syringe (10) for administering injections of medicinal fluids to a patient or withdrawal of fluid, such as blood from a patient. More specifically the present invention is a syringe device (10) for injecting medication or withdrawing fluid, wherein after use the needle (60) is shielded (15) against inadvertent contact to prevent needle sticks.

Abstract: A method, an apparatus, and a computer program product for electromagnetically designing a shaped-reflector multibeam antenna (100) are disclosed. An initial configuration of the multibeam antenna (100) for given beam directions is provided of reflectors (110,120) shaped with an initial reflector shaping process (612) and feeds of an initial specification (614). The initial reflector shaping process (612) is an iterative optimization process for increasing the focusing of optical rays incident on the multibeam antenna from the given beam directions (100). A second iterative optimizing process consisting of optimizing (620) radiation patterns of feeds (140A-140D) and optimizing (622) surface shapes and sizes of reflectors (110,120) is used to reduce beam spillover, improve beam shapes and obtain beams with gain radiation patterns within required upper and lower bounds.

Abstract: A fax device having a memory for storing a list of blocked callers and the capability to receive caller identification information. As calls are received the fax device compares the caller identification information of the incoming call to the list of blocked callers. If the telephone number of the incoming call is contained in the list of blocked callers, a connection is denied. If the number is not contained in the list, the call is connected. The list of blocked callers may be automatically maintained by monitoring incoming calls for frequency, date, time and number of pages. The factors may be combined to determine a usage value. If the usage value exceeds a predetermined threshold, the incoming telephone number may be added to the list of blocked callers. A list of trusted callers prevents trusted phone numbers from accidentally being added to the blocked list. A list of urgent callers includes actions such as forwarding and messaging to determine how to handle a received fax from a certain number.

Abstract: A device is provided for injecting fluid from a pre-filled cartridge. The device includes a needle and a hollow barrel that holds a pre-filled cartridge. A needle retainer releasably retains the needle in an extended position so the needle can be inserted into a patient. A plunger in the rear of the barrel cooperates with the cartridge to expel fluid from the cartridge during an injection. After an injection, the needle is automatically retracted into the barrel when pressure is released from the plunger. A locking mechanism locks the contaminated needle and cartridge in the barrel after needle retraction. After use, the device may be safely disposed of in a sharps container.

Abstract: A safety needle-bearing medical advice (10) is provided. Specifically, a safety device for injecting medicinal fluid into a patient is provided. The device comprises a hollow housing (20), a needle assembly (40) and a plunger (30). The needle assembly (40) releasably retains a needle (45) in an extended position in which the sharpened tip of the needle is exposed for use. At the end of an injection stroke, the plunger (30) engages the needle assembly (40), such that the needle (45) is released and retracted into a cavity (38) within the plunger. The device (10) includes structure for reducing the dead-space volume, which represents the amount a fluid remaining in the device at the end of an injection stroke. In addition, preferably the device (10) includes structure for minimizing the volume of potential air bubbles trapped in the medicinal fluid prior to an injection.

Abstract: A bonding system is provided that bonds a heat sink to a printed circuit assembly. The bonding system includes an adhesive applicator that is configured to hold an adhesive layer, and a heat sink holder that is configured to hold a heat sink while the adhesive applicator applies the adhesive layer to the heat sink.

Abstract: A device is provided for inserting medical instruments, such as pacemaker leads, into a patient. The device includes a flexible needle with a sharpened tip surrounded by a sheath and catheter. A biasing element biases the needle toward a position in which the needle tip is enclosed within the sheath. A method for inserting a medical instrument, such as a pacemaker lead, is also provided, in which the needle is inserted into a patient, followed by the sheath and catheter. The needle is then retracted so that the sharpened tip is enclosed within the sheath. The needle remains in the sheath as the sheath and catheter are curved into alignment with a blood vessel and advanced through the blood vessel. The needle and sheath are then pulled out, and a pacemaker lead or other instrument is fed through the catheter and into the vessel.

Abstract: A method and apparatus are provided for using a medical device (10) comprised of a medical apparatus (20) and a needle assembly (30). The needle assembly includes a needle (70) having a sharpened tip. Preferably, the medical apparatus (20) is a standard apparatus, such as a syringe or phlebotomy device. The medical apparatus (20) includes a connector (24), such as a Luer connector. The needle assembly (30) is configured so that it can be attached to the medical apparatus (20) and the sharpened tip of the needle (70) is automatically shielded after use to prevent inadvertent contact with the contaminated needle.

Abstract: A process by which a user accesses a web site through the use of a mnemonic associated with the desired site, rather than through the use of the site's actual URL. The mnemonic may be text or an audio or video representation. An on-line service converts the mnemonic to a URL, which then can be used by the user to access the target web site.

Abstract: The invention concerns the use of a compound of formula (I), in which Z, X, T, A, R1, R2, p and q have any of the meanings defined herein, and their pharmaceutically acceptable salts or in vivo hydrolysable esters, in the treatment of a disease or condition mediated by monocyte chemoattractant protein-1 (MCP-1). Certain of the components of formula (I) are novel and are provided, together with pharmaceutical compositions thereof, as further features of the invention.

Abstract: A catheter insertion device is provided that includes an insertion needle that is retractable into the device after use to prevent exposure to the contaminated needle. The needle retainer releasably retains the needle in an extended position against the bias of the biasing element. When the catheter is removed from the insertion device, the needle retainer automatically releases the needle, which is propelled rearwardly into the device. A device for inserting a guide wire into a patient is also provided. The device includes an insertion needle that is retractable into the housing of the device after use. A needle retainer releasably retains the needle in an extended position against the bias of the biasing element. The needle retainer engages the guide wire so that when the guide wire is removed from the insertion device, the needle retainer automatically releases the needle, which is propelled into the device.

Abstract: A process for the preparation of arylcyclobutylnitrile derivatives which involves reaction of a solution of a 1,3-dihalopropane and a cyanobenzyl derivative in a substantialy dimethyl sulphoxide-free solvent with a suspension of a base in a substantially dimethyl sulphoxide-free solvent at a temperature of at least 35° C.

Abstract: A device is provided for inserting medical instruments, such as pacemaker leads, into a patient. The device includes a flexible needle with a sharpened tip surrounded by a sheath and catheter. A biasing element biases the needle toward a position in which the needle tip is enclosed within the sheath. A method for inserting a medical instrument, such as a pacemaker lead, is also provided, in which the needle is inserted into a patient, followed by the sheath and catheter. The needle is then retracted so that the sharpened tip is enclosed within the sheath. The needle remains in the sheath as the sheath and catheter are curved into alignment with a blood vessel and advanced through the blood vessel. The needle and sheath are then pulled out, and a pacemaker lead or other instrument is fed through the catheter and into the vessel.

Abstract: The invention concerns quinazoline derivatives of the formula I 1