Abstract: This invention relates to the identification of modified cytosine residues, such as 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) to be distinguished from cytosine (C) in a sample nucleotide sequence. Methods may comprise oxidising or reducing a first portion of polynucleotides which comprise the sample nucleotide sequence; treating the oxidised or reduced first portion and a second portion of polynucleotides with bisulfite; sequencing the polynucleotides in the first and second portions of the population following steps ii) and iii) to produce first and second nucleotide sequences, respectively and; identifying the residue in the first and second nucleotide sequences which corresponds to a cytosine residue in the sample nucleotide sequence. These methods may be useful, for example in the analysis of genomic DNA and/or of RNA.

Abstract: In a communication device using a plurality of signal enhancement mechanisms, a system and method are provided for managing signal processing power consumption. A receiver accepts a communications signal and analyzes signal integrity. In response to analyzing the signal integrity, a signal enhancement mechanism is changed, and device power consumption is modified in response to changing the signal enhancement mechanism. In one aspect, the receiver changes a receiver signal enhancement mechanism, and modifies its power consumption. For example, one or more of the following receiver signal enhancement mechanisms may be selected: forward error correction (FEC), equalization, dc voltage level, and physical coding sublayer (PCS).

Abstract: A system and method are provided for securing links at the physical (PHY) layer in an IEEE 802.3 Ethernet communication system. A local device (LD) receives an electrical waveform representing link partner security information from a network-connected link partner (LP) via unformatted message pages. The LD accesses predetermined LP reference information stored in a tangible memory medium. The LD compares the received LP security information to the LP reference information. In response to the LD matching the received LP security information to the LP reference information, a secure link to the LP is verified. Likewise, the LD may send electrical waveforms representing security information to the LP via the unformatted message pages. In response to the LP matching the LD security information to the LD reference information, a secure link to the LD is verified.

Abstract: A method for spraying a food product is disclosed herein. The method includes the step of disposing a first sprayer along an axis defining, at least in part, a path of movement for a food product. The method also includes the step of disposing a second sprayer along the axis axially and radially spaced from the first sprayer. The method also includes the step of directly communicating with the first and second sprayers disposed along the axis with a cavity operable to receive edible ink such that the first and second sprayers concurrently spray the edible ink to the axis.

Abstract: A system and method are provided for accelerating forward error correction (FEC) synchronization in a communicating receiver. On the transmitter side, the method accepts an energy waveform representing a packet of data symbols, encodes the packet, and creates an FEC block. Prior to transmitting the FEC block, an electromagnetic waveform is transmitted representing an FEC flag character. Then, an electromagnetic waveform representing the FEC block is transmitted a predetermined first period of time after the transmission of the FEC flag character. For example, the first time period may be immediately following the FEC flag character transmission or a predetermined number of idle characters following the transmission of the FEC flag character.

Abstract: Disclosed is a method for printing a media sheet in a media processing device. The method includes aligning a first portion of a printhead of the media processing device to a print area of the media sheet. The method further includes printing the print area of the media sheet by traversing the printhead over the print area in a first direction. The printing is performed by the first portion. Further, the method includes aligning a second portion of the printhead to the print area by adjusting the media sheet relative to the printhead by an index distance in a direction perpendicular to the first direction. Thereafter, the method includes reprinting the print area by traversing the printhead over the print area in a second direction opposite to the first direction. The reprinting is performed by the second portion.

Abstract: A computer for use in the transfer and monitoring of data and a method of verifying the transfer of patient physiological data is herein disclosed. The computer comprises a display for displaying data, a controller for controlling the display of the data, a graphical user interface being disposed to display data, a first input device connected to the controller for entering data that is recorded and displayed by a data recording device and a second input device connected to the controller for entering data into the controller that is indicative of the spatial arrangement of the display of the data by the data recording device, wherein the controller uses the data indicative of the spatial arrangement of the display of data by the data recording device to display the data in the graphical user interface according to the data by the data recording device.

Abstract: A method for compressing data includes transmitting a requested compression factor such as a quality factor known in JPEG compression, to a scanner or like peripheral device. The type of communication link between the scanner or like device and a host computer is identified, and based on the communication link type, the requested compression factor is altered to generate a new compression factor subsequently used to compress the data. The amount of buffer, such as scan buffer, used by the scanner or peripheral device may also be used to alter the compression factor prior to compression.

Abstract: A method of making an article 2 comprising an ultra-thin sheet 26 of material secured at lateral regions to a support member, the method comprises laying the ultra-thin sheet on a substrate 20, forming the support member on the lateral regions of the ultra-thin sheet such that the lateral regions of the ultra-thin sheet are sandwiched between the support member and the substrate and adhered to the support member, and removing the substrate by vaporisation or by a dissolution step using a solvent, to leave the article. The ultra-thin sheet is supported around its periphery and has a central region in which the ultra-thin sheet is free from contact with any other material.

Abstract: A method for printing of raster data in a media processing device is disclosed. The method includes identifying an attribute of a set of raster lines of the raster data. The method further includes determining at least one print mode from a plurality of print modes based on the attribute. Each print mode of the plurality of print modes is configured to print the set of raster lines of the raster data. Furthermore, the method includes printing the set of raster lines of the raster data in the at least one print mode.

Abstract: A system and method are provided for accelerating forward error correction (FEC) synchronization in a communicating receiver. On the transmitter side, the method accepts an energy waveform representing a packet of data symbols, encodes the packet, and creates an FEC block. Prior to transmitting the FEC block, an electromagnetic waveform is transmitted representing an FEC flag character. Then, an electromagnetic waveform representing the FEC block is transmitted a predetermined first period of time after the transmission of the FEC flag character. For example, the first time period may be immediately following the FEC flag character transmission or a predetermined number of idle characters following the transmission of the FEC flag character.

Abstract: Disclosed is a method for printing a media sheet in a media processing device. The method includes aligning a first portion of a printhead of the media processing device to a print area of the media sheet. The method further includes printing the print area of the media sheet by traversing the printhead over the print area in a first direction. The printing is performed by the first portion. Further, the method includes aligning a second portion of the printhead to the print area by adjusting the media sheet relative to the printhead by an index distance in a direction perpendicular to the first direction. Thereafter, the method includes reprinting the print area by traversing the printhead over the print area in a second direction opposite to the first direction. The reprinting is performed by the second portion.

Abstract: A system and method are provided for securing links at the physical (PHY) layer in an IEEE 802.3 Ethernet communication system. A local device (LD) receives an electrical waveform representing link partner security information from a network-connected link partner (LP) via unformatted message pages. The LD accesses predetermined LP reference information stored in a tangible memory medium. The LD compares the received LP security information to the LP reference information. In response to the LD matching the received LP security information to the LP reference information, a secure link to the LP is verified. Likewise, the LD may send electrical waveforms representing security information to the LP via the unformatted message pages. In response to the LP matching the LD security information to the LD reference information, a secure link to the LD is verified.

Abstract: A hydromassage bathtub includes a bathtub including a sidewall, a deck, and an access opening in one of the sidewall and the deck. A fixture is secured to an outside surface of the bathtub proximate the access opening, and a removable plate configured to cover the access opening. A system component such as a control box is removably mounted on the fixture at a position whereby, upon removal of the plate, the system component can be removed from the fixture by accessing it through the access opening.

Abstract: An article of manufacture and method is disclosed to design an interior space having a plurality of components that includes displaying a plurality of interior design elements each having a common first attribute within a first attribute group, with the first attribute associated with a first interior space component. Further, the method of designing the interior space includes displaying a plurality of interior design elements each having a common second attribute within a second attribute group, with the second attribute associated with a second interior space component. Continuing, the method of designing the interior space includes selecting one the interior design elements from each group defined by the first attribute and second attribute. In addition, displaying each of the selected interior design elements from the first and second attribute groups on their respective associated first and second interior space components, all within the interior space.

Abstract: A method of printing a high resolution image with a printhead in a multi-pass printing mode includes subdividing the high resolution image into a plurality of low resolution sub-images; subdividing each low resolution sub-image into a plurality of low resolution swath portions; and allocating an amount of a memory for buffer storage, the amount being only sufficient to store data corresponding to less than two of the low resolution swath portions. The method also includes, for each low resolution swath portion: halftoning each low resolution swath portion to generate a corresponding halftoned low resolution swath portion, the halftoning of each low resolution swath portion of a particular low resolution sub-image being performed independently of halftoning the low resolution swath portions of other low resolution sub-images; storing the halftoned low resolution swath portion into the amount of the memory; and printing the halftoned low resolution swath portion.

Abstract: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4).

Abstract: A computer for use in the transfer and monitoring of data and a method of verifying the transfer of patient physiological data is herein disclosed. The computer comprises a display for displaying data, a controller for controlling the display of the data, a graphical user interface being disposed to display data, a first input device connected to the controller for entering data that is recorded and displayed by a data recording device and a second input device connected to the controller for entering data into the controller that is indicative of the spatial arrangement of the display of the data by the data recording device, wherein the controller uses the data indicative of the spatial arrangement of the display of data by the data recording device to display the data in the graphical user interface according to the data by the data recording device.

Abstract: A method and system for playing media are disclosed. The media play system comprises a media server comprising a plurality of outputs, wherein each of the plurality of outputs is connected to a playback station, wherein the media server is connected to at least one device that is configured to store digital content, and wherein the at least one device comprises either a mobile media player docked in a mobile media docking mechanism or a local network connected to a media track storage. The method comprises media retrieving a plurality of media tracks stored in a plurality of devices, wherein each of the plurality of devices comprises either a mobile media player docked in a mobile media docking mechanism or a local network connected to a media track storage and wherein the media tracks stored therein are seen as a single collection of tracks and substantially simultaneously outputting the plurality of media tracks to a plurality of playback stations.

Abstract: A method for spraying a food product is disclosed herein. The method includes the step of disposing a first sprayer along an axis defining, at least in part, a path of movement for a food product. The method also includes the step of disposing a second sprayer along the axis axially and radially spaced from the first sprayer. The method also includes the step of directly communicating with the first and second sprayers disposed along the axis with a cavity operable to receive edible ink such that the first and second sprayers concurrently spray the edible ink to the axis.