Abstract: A method of fabricating synthetic diamond material using a microwave plasma activated chemical vapour deposition technique is provided which utilizes high and uniform microwave power densities applied over large areas and for extended periods of time. Products fabricated using such a synthesis technique are described including a single crystal CVD diamond layer which has a large area and a low nitrogen concentration, and a high purity, fast growth rate single crystal CVD diamond material.

Abstract: Provided herein are E. coli host strains with improved capacity for producing recombinant proteins.

Abstract: Provided herein are E. coli host strains with improved capacity for producing recombinant proteins.

Abstract: Provided herein are methods for the improved production of periplasmic-targeted recombinant proteins in E. coli host strains. Also provided are E. coli host strains with improved capacity for producing recombinant proteins.

Abstract: A method of coating a non-refractory and/or non-planar substrate (8) with synthetic diamond material using a microwave plasma chemical vapour deposition (CVD) synthesis technique, the method comprising: forming a composite substrate assembly (1) comprising: a support substrate (2) comprising an upper surface; one or more electrically conductive refractory guards (6) disposed over the upper surface of the support substrate and extending to a height hg above the upper surface of the support substrate; and one or more non-refractory and/or non-planar substrates disposed over the upper surface of the support substrate and extending to a height hs above the upper surface of the support substrate, wherein the height hs is less than the height hg, wherein a difference in height hg?hs lies in a range 0.

Abstract: A synthetic diamond plate comprising a polygonal plate formed of synthetic diamond material, the polygonal plate of synthetic diamond material having a thickness in a range 0.4 mm to 1.5 mm, and rounded corners having a radius of curvature in a range 1 mm to 6 mm. A mounted synthetic diamond plate is also disclosed comprising a polygonal synthetic diamond plate as described and a base to which the polygonal synthetic diamond plate is bonded, wherein the base comprises a cooling channel. An array of mounted synthetic diamond plates is also described, comprising a plurality of mounted synthetic diamond plates described above, wherein the cooling channels of the mounted synthetic diamond plates are linked to form a common cooling channel across the array of mounted synthetic diamond plates.

Abstract: A synthetic diamond plate comprising a polygonal plate formed of synthetic diamond material, the polygonal plate of synthetic diamond material having a thickness in a range 0.4 mm to 1. mm, and rounded corners having a radius of curvature in a range 1 mm to 6 mm. A mounted synthetic diamond plate is also disclosed comprising a polygonal synthetic diamond plate as described and a base to which the polygonal synthetic diamond plate is bonded, wherein the base comprises a cooling channel. An array of mounted synthetic diamond plates is also described, comprising a plurality of mounted synthetic diamond plates described above, wherein the cooling channels of the mounted synthetic diamond plates are linked to form a common cooling channel across the array of mounted synthetic diamond plates.

Abstract: A method of fabricating synthetic diamond material using a microwave plasma activated chemical vapour deposition technique is provided which utilizes high and uniform microwave power densities applied over large areas and for extended periods of time. Products fabricated using such a synthesis technique are described including a single crystal CVD diamond layer which has a large area and a low nitrogen concentration, and a high purity, fast growth rate single crystal CVD diamond material.

Abstract: The present invention relates to the use of redox agents for purification of the CRM 197 variant of diphtheria toxin. The invention further relates to multi-step purification of CRM 197 from bacterial fermentates.

Abstract: A synthetic diamond plate comprising a polygonal plate formed of synthetic diamond material, the polygonal plate of synthetic diamond material having a thickness in a range 0.4 mm to 1. mm, and rounded corners having a radius of curvature in a range 1 mm to 6 mm. A mounted synthetic diamond plate is also disclosed comprising a polygonal synthetic diamond plate as described and a base to which the polygonal synthetic diamond plate is bonded, wherein the base comprises a cooling channel. An array of mounted synthetic diamond plates is also described, comprising a plurality of mounted synthetic diamond plates described above, wherein the cooling channels of the mounted synthetic diamond plates are linked to form a common cooling channel across the array of mounted synthetic diamond plates.

Abstract: Provided herein are methods for the improved production of periplasmic-targeted recombinant proteins in E. coli host strains. Also provided are E. coli host strains with improved capacity for producing recombinant proteins.

Abstract: The present invention relates to the use of redox agents for purification of the CRM 197 variant of diphtheria toxin. The invention further relates to multi-step purification of CRM 197 from bacterial fermentates.

Abstract: A method of fabricating synthetic diamond material using a microwave plasma activated chemical vapour deposition technique is provided which utilizes high and uniform microwave power densities applied over large areas and for extended periods of time. Products fabricated using such a synthesis technique are described including a single crystal CVD diamond layer which has a large area and a low nitrogen concentration, and a high purity, fast growth rate single crystal CVD diamond material.

Abstract: Method of reclaiming and inhibiting activation of DRI fines is disclosed comprising the steps of forming a moving stream or pile containing DRI pellets and DRI fines, coating the moving stream or the pile of DRI pellets and DRI fines with a coating material comprising an alkane mixture in the C15 to C40 range to form a coating on the DRI pellets and DRI fines and cause DRI fines to adhere together and to the DRI pellets to form a plurality of agglomerates, and moving the agglomerates of coated DRI pellets and coated DRI fines to a facility for use in making steel. The coating material may be applied to coat the DRI pellets and DRI fines at a rate between 0.2 and 2.0 gallons per ton of DRI processed. The coating material may be mineral oil.

Abstract: A method of coating a non-refractory and/or non-planar substrate (8) with synthetic diamond material using a microwave plasma chemical vapour deposition (CVD) synthesis technique, the method comprising: forming a composite substrate assembly (1) comprising: a support substrate (2) comprising an upper surface; one or more electrically conductive refractory guards (6) disposed over the upper surface of the support substrate and extending to a height hg above the upper surface of the support substrate; and one or more non-refractory and/or non-planar substrates disposed over the upper surface of the support substrate and extending to a height hs above the upper surface of the support substrate, wherein the height hs is less than the height hg, wherein a difference in height hg?hs lies in a range 0.

Abstract: A method of reclaiming and inhibiting activation of DRI including forming a moving stream or pile containing DRI pellets and DRI fines and applying to said DRI material a coating material optionally having a melting point between 70 and 200° F. and comprising at least one antioxidant and at least one a carboxylic material with at least one selected from the group consisting of coatable fatty acid and an esterified derivative thereof, forming a coating on the DRI pellets and DRI fines to cause the fines to adhere together and to the pellets to form a plurality of DRI agglomerates. The coating material may be selected from the group consisting of palm oil, coconut oil, combinations thereof, and ester derivatives thereof. The antioxidant in the coating material is selected from the group consisting of at least one of butylated hydroxytoluene, carotenoid, phytosterol, squalene, vitamin E, tocopherols, tocotrienols, and mixtures thereof.

Abstract: Method of reclaiming and inhibiting activation of DRI fines is disclosed comprising the steps of forming a moving stream or pile containing DRI pellets and DRI fines, coating the moving stream or the pile of DRI pellets and DRI fines with a coating material comprising an alkane mixture in the C15 to C40 range to form a coating on the DRI pellets and DRI fines and cause DRI fines to adhere together and to the DRI pellets to form a plurality of agglomerates, and moving the agglomerates of coated DRI pellets and coated DRI fines to a facility for use in making steel. The coating material may be applied to coat the DRI pellets and DRI fines at a rate between 0.2 and 2.0 gallons per ton of DRI processed. The coating material may be mineral oil.

Abstract: A method of reclaiming and inhibiting activation of DRI including forming a moving stream or pile containing DRI pellets and DRI fines and applying to said DRI material a coating material optionally having a melting point between 70 and 200° F. and comprising at least one antioxidant and at least one a carboxylic material with at least one selected from the group consisting of coatable fatty acid and an esterified derivative thereof, forming a coating on the DRI pellets and DRI fines to cause the fines to adhere together and to the pellets to form a plurality of DRI agglomerates. The coating material may be selected from the group consisting of palm oil, coconut oil, combinations thereof, and ester derivatives thereof. The antioxidant in the coating material is selected from the group consisting of at least one of butylated hydroxytoluene, carotenoid, phytosterol, squalene, vitamin E, tocopherols, tocotrienols, and mixtures thereof.

Abstract: Nitrosamines are reduced in tobacco by treating a whole tobacco leaf with ferulic acid. Treatment is conducted by applying an aqueous solution of ferulic acid to the whole tobacco leaf immediately before, at, or after harvesting, or fire curing the whole tobacco leaf with wood smoke containing the ferulic acid.

Abstract: Nitrosamines are reduced in tobacco by treating a whole tobacco leaf with ferulic acid. Treatment is conducted by applying an aqueous solution of ferulic acid to the whole tobacco leaf immediately before, at, or after harvesting, or fire curing the whole tobacco leaf with wood smoke containing the ferulic acid.