Abstract: The present invention relates to the use of redox agents for purification of the CRM 197 variant of diphtheria toxin. The invention further relates to multi-step purification of CRM 197 from bacterial fermentates.

Abstract: An eyeglass assembly with a bridge frame having temple tab thru-holes and lens retention receivers; a nose bridge insert; at least one lens in a single lens configuration with tabs configured to insert into the lens retention receivers of the bridge frame such that the lens tabs, or a portion thereof, protrude through temple tab thru-holes. In some embodiments, the eyeglasses are frameless, having first and second temple lugs with temple tab thru-holes and lens locking features; at least one lens in a single lens configuration having lens tabs, lens retention steps, lug locking notches; and a nose bridge insert. In some embodiments, the eyeglass assembly has a bridge frame with an integral nose bridge, two lenses, each lens having a lens tab, and a lens retention step, further having a lens hook.

Abstract: An eyeglass assembly with a bridge frame having temple tab thru-holes and lens retention receivers; a nose bridge insert; at least one lens in a single lens configuration with tabs configured to insert into the lens retention receivers of the bridge frame such that the lens tabs, or a portion thereof, protrude through temple tab thru-holes. In some embodiments, the eyeglasses are frameless, having first and second temple lugs with temple tab thru-holes and lens locking features; at least one lens in a single lens configuration having lens tabs, lens retention steps, lug locking notches; and a nose bridge insert. In some embodiments, the eyeglass assembly has a bridge frame with an integral nose bridge, two lenses, each lens having a lens tab, and a lens retention step, further having a lens hook.

Abstract: A computer-implemented system includes a plurality of metrological interface devices. Each metrological interface device is in communication with a metrological sensing device configured to detect metrological data from a physical asset. The computer-implemented system also includes a portable computing device. The portable computing device is configured to a) receive a metrological data set, the metrological data set substantially representing data associated with the physical asset at a point in time, b) process the metrological data set and an asset data model into a processed metrological data set, c) upon determining, based on the processed metrological data set, a metrological variance, recalibrating the asset data model and returning to step (a), and d) upon determining no metrological variance, reporting the metrological data set and the asset data model to at least one report recipient.

Abstract: An eyeglass assembly with a bridge frame having temple tab thru-holes and lens retention receivers; a nose bridge insert; at least one lens in a single lens configuration with tabs configured to insert into the lens retention receivers of the bridge frame such that the lens tabs, or a portion thereof, protrude through temple tab thru-holes. In some embodiments, the eyeglasses are frameless, having first and second temple lugs with temple tab thru-holes and lens locking features; at least one lens in a single lens configuration having lens tabs, lens retention steps, lug locking notches; and a nose bridge insert. In some embodiments, the eyeglass assembly has a bridge frame with an integral nose bridge, two lenses, each lens having a lens tab, and a lens retention step, further having a lens hook.

Abstract: An eyeglass assembly with a bridge frame having temple tab thru-holes and lens retention receivers; a nose bridge insert; at least one lens in a single lens configuration with tabs configured to insert into the lens retention receivers of the bridge frame such that the lens tabs, or a portion thereof, protrude through temple tab thru-holes. In some embodiments, the eyeglasses are frameless, having first and second temple lugs with temple tab thru-holes and lens locking features; at least one lens in a single lens configuration having lens tabs, lens retention steps, lug locking notches; and a nose bridge insert. In some embodiments, the eyeglass assembly has a bridge frame with an integral nose bridge, two lenses, each lens having a lens tab, and a lens retention step, further having a lens hook.

Abstract: A method implemented using one or more computer processors for estimating the density of a material in an annular space includes receiving detector data representative of scattered photons resulting from interaction of a material in an annular space with radiation from a radiation source and detected by a plurality of radiation detectors. The technique further includes performing a set of Monte Carlo simulations. The method further includes performing a principal component analysis on the set of Monte Carlo simulations to generate a principal component analysis model of the detector data. The method also includes estimating the density of the material at one or more locations within the annular space based upon the principal component analysis model and the detector data.

Abstract: System architecture that provides computer-based methods of wireless communication between a wireless metrological device and a mobile computing device that includes the sending/receiving of data (e.g., measurements) along with a universal generic data service that includes data descriptor(s) affiliated with the measurements. The architecture and methods, which may be communicated via BLE, allow for uniform communication between tools and mobile computing devices regardless of tool type, manufacturer, and measurement information.

Abstract: A system includes a light emitting unit, a front mirror, a rear mirror, an imaging unit and a processor. The light emitting unit is configured to emit a collimated light beam. The front mirror is configured to reflect part of the collimated light beam to produce and project a front focused ring of structured light to an object to obtain a front reflected ring of light, and configured to allow part of the collimated light beam to pass by. The rear mirror is positioned downstream of a light transmitting path of the front mirror. The rear mirror is configured to reflect at least part of the collimated light beam passing by the front mirror to produce and project a rear focused ring of the structured light to the object to obtain a rear reflected ring of light.

Abstract: System and method for promoting enterprise adoption of a web-based collaboration environment are disclosed. In one aspect, embodiments of the present disclosure include a method, which may be implemented on a system, for detecting eligibility of a user having an account in the web-based collaboration environment, for the user to invite additional users to join the web-based collaboration environment, providing the user with a mechanism to invite the additional users to join the web-based collaboration environment to create accounts with enhanced features, and/or sending, to those of the additional users who qualify, an invitation to create new accounts in the web-based collaboration environment, those of the additional users who qualify are affiliated with the enterprise of the user having the account. The new accounts that are created include the enhanced features.

Abstract: System and method for promoting enterprise adoption of a web-based collaboration environment are disclosed. In one aspect, embodiments of the present disclosure include a method, which may be implemented on a system, for detecting eligibility of a user having an account in the web-based collaboration environment, for the user to invite additional users to join the web-based collaboration environment, providing the user with a mechanism to invite the additional users to join the web-based collaboration environment to create accounts with enhanced features, and/or sending, to those of the additional users who qualify, an invitation to create new accounts in the web-based collaboration environment, those of the additional users who qualify are affiliated with the enterprise of the user having the account. The new accounts that are created include the enhanced features.

Abstract: System and method for actionable event generation for task delegation and management via a discussion forum in a web-based collaboration environment are disclosed. In one aspect, embodiments of the present disclosure include a method, which may be implemented on a system, for creating an actionable event via a discussion forum in a web-based collaboration environment. The method includes, for creating an actionable event via a discussion forum in a web-based collaboration environment, where, through commenting, the user is able to create the actionable event relating to the work item.

Abstract: A metrological interface device includes a printed circuit board (“PCB”) including at least one metrological sensor communication interface and at least one first wireless communication interface. The metrological interface device is in communication with a metrological sensing device via the metrological sensor communication interface. Each metrological sensing device is coupled to a physical asset. Each metrological interface device is configured to receive the metrological data from the metrological sensing device. The metrological interface device is configured to receive metrological data from the metrological sensing device via the metrological sensor communication interface. Metrological data represents physical measurement data associated with the physical asset.

Abstract: A measurement system for determining dimensions of a measurement zone of a physical asset is presented. The system includes a telescoping gauge configured to determine one or more analog measurements corresponding to the measurement zone of the physical asset, where the telescoping gauge includes a sliding arm and a vertical arm. Furthermore, the system includes a data digitizer operatively coupled to the telescoping gauge and configured to convert the one or more analog measurements to corresponding one or more digital measurements. In addition, the system includes a wireless unit operatively coupled to the telescoping gauge and configured to wirelessly transmit the one or more digital measurements.

Abstract: According to some embodiments, system comprises a metrological device operative to collect and transmit measurement data; and a hands-free communication device operative to receive the collected data and communicate the data to a user. Numerous other aspects are provided.

Abstract: A method of fabricating synthetic diamond material using a microwave plasma activated chemical vapour deposition technique is provided which utilizes high and uniform microwave power densities applied over large areas and for extended periods of time. Products fabricated using such a synthesis technique are described including a single crystal CVD diamond layer which has a large area and a low nitrogen concentration, and a high purity, fast growth rate single crystal CVD diamond material.