Abstract: A network appliance is configured to determine a security policy controlled by a system of an organization. The network appliance creates an association between the security policy and support agent access to the system. The network appliance creates portals where the access is based on the security policy and access includes connectivity for providing remote support service to the system from a remote support service disconnected from the system.

Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerization and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).

Abstract: Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy and for delivery by oral or nasal inhalation are provided, wherein said compositions additionally comprise particles of at least one additional active agent. Also provided are methods of preparation of the compositions and their use in medicine.

Abstract: Methods and systems for the optimization of available computing resources within a virtual environment are disclosed. An exemplary method comprises determining the sizes of the computing resources available to the virtual machine and determining optimal data structures for the virtual machine based on the sizes of the computing resources. The optimal data structures may include an indexing data structure and a historic data. The method may further comprise allocating a Random Access Memory (RAM) and disk storage to the optimal data structures and configuring the optimal data structures within the RAM and the disk storage. The optimization of data structures involves balancing requirements of the indexing data structure and the historic data.

Abstract: A summer style ski having three different types of wheels aligned to allow the ski to travel on non-snow or ice surfaces and to create the feel of carving or turning on a paved surface.

Abstract: Medical systems and methods for treating kidney disease alone, heart failure alone, kidney disease with concomitant heart failure, or cardiorenal syndrome are described. The systems and methods are based on delivery of a chimeric natriuretic peptide to a patient. Methods for increasing peptide levels include direct peptide delivery via either an external or implantable programmable pump.

Abstract: An approach is provided for a secure remote access and control in a shared resource model. The approach involves initiating a logically separate instance of a virtual appliance using one or more shared computing resources of at least one shared resource provider. The approach also involves initiating an agent at an administrator system associated with the logically separate instance of the virtual appliance, wherein the agent services authentication requests directed to the virtual appliance by acting as a proxy or a push agent to the at least one shared resource provider.

Abstract: An approach is described for securely and automatically handling credentials when used for accessing endpoints, and/or applications and resources on the endpoints.

Abstract: A system for matching data using flow based packet data storage includes a communications interface and a processor. A communications interface receives a packet between a source and a destination. The processor identifies a flow between the source and the destination based on the packet. The processor determines whether some of packet data of the packet indicates a potential match to data in storage using hashes. The processor then stores the data from the most likely data match and second most likely data match without a packet header in a block of memory in the storage based on the flow.

Abstract: A summer style ski having three different types of wheels aligned to allow the ski to travel on non-snow or ice surfaces and to create the feel of carving or turning on a paved surface.

Abstract: A wafer container an enclosure portion including a top wall, a bottom wall, a pair of side walls, a back wall, and a door frame opposite the back wall, the door frame defining a front opening, and a wafer support structure including two side wafer supports 5 each side wafer support including a removable backstop. The invention includes maintaining wafer containers by replacing the removable backstop. The invention includes converting shipping containers that ship large diameter wafers vertically to containers to be used in fabrication facilities that store wafers horizontally for robotic pickup for processing.

Abstract: Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerisation and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).

Abstract: Systems and methods for pre-fetching of data in a memory are provided. By pre-fetching stored data from a slower memory into a faster memory, the amount of time required for data retrieval and/or processing may be reduced. First, data is received and pre-scanned to generate a sample fingerprint. Fingerprints stored in a faster memory that are similar to the sample fingerprint are identified. Data stored in the slower memory associated with the identified stored fingerprints is copied into the faster memory. The copied data may be compared to the received data. Various embodiments may be included in a network memory architecture to allow for faster data matching and instruction generation in a central appliance.

Abstract: According to various embodiments, methods and systems for determining pressure in an inflatable cuff of a tracheal tube may employ pressure transducers associated with a cuff inflation line or a pilot balloon assembly. The pressure transducers may be implemented to provide continuous or intermittent cuff pressure. Also provided are tracheal tubes with adapters or other devices that incorporate pressure transducers. The tracheal tubes may facilitate wireless cuff pressure monitoring.

Abstract: Fluid delivery devices, systems and methods. The fluid delivery devices may be used to delivery fluid (e.g., insulin) to a user. The devices may have one or more inlets, and may be configured for use with an injection device, such as a syringe, and/or with a pump.

Abstract: The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.

Abstract: A system for matching data using flow based packet data storage includes a communications interface and a processor. A communications interface receives a packet between a source and a destination. The processor identifies a flow between the source and the destination based on the packet. The processor determines whether some of packet data of the packet indicates a potential match to data in storage using hashes. The processor then stores the data from the most likely data match and second most likely data match without a packet header in a block of memory in the storage based on the flow.

Abstract: The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.

Abstract: Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy and for delivery by oral or nasal inhalation are provided, wherein said compositions additionally comprise particles of at least one additional active agent. Also provided are methods of preparation of the compositions and their use in medicine.