Abstract: The invention relates to a breathing assistance apparatus that may be configured to reduce the risk of damage to electronics within the apparatus as a result of liquid leaks within the apparatus or impacts to the apparatus. In other forms, the apparatus may be configured to allow for easy assembly and/or safe operation.

Abstract: A survey tool system (100) for surveying deviation of a previously drilled hole (10, 20) from a selected hole path (30) comprises: an assembly of drill pipe sections (55) co-operable with said previously drilled hole (10, 20); and at least one sensor (125) included within the assembly of drill pipe sections (55) for collecting survey data including data correlated with deviation of said previously drilled hole (10, 20) from said selected hole path (30). A processor (130) processes data collected from the at least one sensor (125) and determines deviation of the previously drilled hole (10, 20) from the selected path (30) for said previously drilled hole (10, 20).

Abstract: A medical device such as a stent or medical balloon is functionalised prior to coating with a bioactive material, specifically by carboxylic acidification of the contact surface or surfaces of the medical device. The preferred process involves washing a stent or other medical device in a washing solution which may be sodium hydroxide, soaking in a carboxylic acid solution, rinsing in water to remove excess carboxylic acid, allowing to dry before applying a bioactive agent layer. It has been found that washing after functionalisation removes excess carboxylic acid and enhances the retention of bioactive agent on the contact surface or surfaces of the medical device leading to a more uniform and consistent layer of bioactive agent.

Abstract: A compliance discovery and integration process is implemented in association with a cloud-based security and compliance platform and associated CI/CD framework. The process assumes an existing DevOps-based deployment of a product, such as an enterprise application that executes in a runtime production environment. The technique of this disclosure addresses the problem of misalignment between a compliance policy and the product's post-deployment regulation posture by providing tools and methods that enable pro-active augmentation of governance and compliance policy during the pre-deployment phase and with respect to a next deployment of the product (e.g., a next or updated version). Thus, when the product is later deployed in its next deployment, its regulation posture (post-deployment) is already consistent with the compliance policy.

Abstract: A filter cartridge for a pool or spa includes a fluid flow path into the filter cartridge, and the orientation of the fluid flow path is adjustable. A diverter may be provided within a housing of the filter cartridge for adjusting the orientation of the fluid flow path of the pool water entering the housing. The diverter may be detachable and allow multiple angular settings directing flow. Additionally, or alternatively, the filter cartridge includes internal vertical ribs for directing debris caught by the filter cartridge.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.

Abstract: A method, apparatus and computer program product for automated security and regulatory compliance in association with an enterprise. A set of security and compliance controls that operate in association with the enterprise are provided. One or more compliance policies that are enforced by the set of security and compliance controls are encapsulated according to a common data format. One or more customer-specific security/compliance requirements associated with the enterprise are collected. Using microservices-based modular components, the customer-specific security/compliance requirements are then transformed into machine-readable representations having the common data format and that conform to the one or more compliance policies being enforced by the set of security and compliance controls. The one or more compliance policies including the one or more transformed security/compliance requirements are then activated to facilitate the security and regulatory compliance.

Abstract: A compliance discovery and integration process is implemented in association with a cloud-based security and compliance platform and associated CI/CD framework. The process assumes an existing DevOps-based deployment of a product, such as an enterprise application that executes in a runtime production environment. The technique of this disclosure addresses the problem of misalignment between a compliance policy and the product’s post-deployment regulation posture by providing tools and methods that enable pro-active augmentation of governance and compliance policy during the pre-deployment phase and with respect to a next deployment of the product (e.g., a next or updated version). Thus, when the product is later deployed in its next deployment, its regulation posture (post-deployment) is already consistent with the compliance policy.

Abstract: A safety system for an automated storage and picking system is described. The storage system includes load handling devices operating above a series of stacked containers located within a framework, the top of which includes tracks on which the load handling devices operate. The safety system includes a transmitter located in close proximity to the storage system and a receiver located on each of the load handling devices. The transmitter can continually transmit a signal that is detected by the receivers on the load handling devices. In the event of an emergency or a breach of the storage system, the transmission of the signal is cut. Once the receiver no longer receives the signal from the transmitter, power to each load handling device drive is cut to render the storage system safe.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.

Abstract: The present disclosure provides systems, methods, and devices for the simultaneous determination of a single cell's response to a stimuli and characterization of its cell response. The present disclosure further provides methods for detection of disease state, clinical management of a subject suffering from a disease, drug screening, prediction of drug response, and stands to help direct drug and diagnostic development for the treatment of disease.

Abstract: One embodiment describes a network system. The system includes a primary enclosure including a network switch system that includes a plurality of physical interface ports. A first one of the plurality of physical interface ports is to communicatively couple to a network. The system further includes a sub-enclosure comprising a network interface card (NIC) to which a computer system is communicatively coupled and a downlink extension module (DEM) that is communicatively coupled with the NIC and a second one of the plurality of physical interface ports of the network switch system to provide network connectivity of the computer system to the network via the network switch system.

Abstract: A technique relates to communication resource allocation. A computer system monitors a communication between a conversational entity communication channel and a user device. A type of the communication associated with the user device is determined based on the communication. A replacement communication channel to replace the conversational entity communication channel is determined, in response to the type of the communication. The replacement communication channel is coupled to the user device in place of the conversational entity communication channel.

Abstract: A method for displaying a visual representation corresponding to a carriage capacity may include obtaining passenger data of passengers onboard a carriage of a multi-carriage vehicle. The method may further include predicting, based at least in part on the first passenger data, a number of passengers who will exit the carriage at a destination. The method may further include determining, based at least in part on the predicting, an available capacity for the carriage and generating a visual representation that corresponds to the available capacity. The method may further include displaying the visual representation at the destination of the multi-carriage vehicle.

Abstract: Segmentation and classification of documents in a mixed security environment includes receiving a document including a plurality of subcomponents. A security classification level of each of the plurality of subcomponents is determined using a first classification model. The security classification level of each subcomponent includes one of a first classification level and a second classification level. A first subcomponent having the first classification level is routed to a first environment having a first security level. A second subcomponent having the second classification level is routed to a second environment having a second security level. A pointer for the second subcomponent is determined in which the pointer references a portion of the first subcomponent.

Abstract: Provided herein is a method of isolating cellular components from at least one region of interest in a planar tissue section.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.

Abstract: An electrical supply system including a voltage converter including having an input electrically coupled to a supply for receiving a supply signal and an output for supplying an output signal having a output voltage different to a supply voltage of the supply signal. The system includes a diode including a diode input electrically coupled to the voltage converter output, a bus electrically coupled to a diode output and at least one of a load and a store, a voltage sensor for detecting the output voltage, a current sensor for detecting a diode input current and an electronic processing device coupled to the sensors for monitoring the diode input current and the output voltage and detecting a fault in the electrical supply system based on at least the diode input current and output voltage.

Abstract: A technique relates to communication resource allocation. A computer system monitors a communication between a conversational entity communication channel and a user device. A type of the communication associated with the user device is determined based on the communication. A replacement communication channel to replace the conversational entity communication channel is determined, in response to the type of the communication. The replacement communication channel is coupled to the user device in place of the conversational entity communication channel.