Patents by Inventor John C. Chabala

John C. Chabala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140135290
    Abstract: The present invention includes macrocyclic prodrug compounds, pharmaceutical compositions containing them. The present invention also includes use of these compounds in the treatment of various diseases including an autoimmune disease, an inflammatory disease, a neurological or neurodegenerative disease, cancer, a cardiovascular disease, allergy, asthma, a hormone-related disease, and tumors or symptoms resulting from neurofibromatosis.
    Type: Application
    Filed: November 4, 2013
    Publication date: May 15, 2014
    Applicants: ONCOSYNERGY, INC., LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE STRASBOURG
    Inventors: James HECK, Nicolas Winssinger, John C. Chabala, Sofia Barluenga, Ruihong Chen, Allan Rubenstein, Jin-Chen Yu
  • Patent number: 8658656
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: February 25, 2014
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustav S Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Patent number: 8470838
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: August 25, 2009
    Date of Patent: June 25, 2013
    Assignee: Cytokinetics, Incorporated
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Publication number: 20130053408
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Application
    Filed: September 12, 2012
    Publication date: February 28, 2013
    Inventors: Jeffrey T. Finer, Gustave S. Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Patent number: 8008311
    Abstract: Quinazolinones of formulae (a, b, c and d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: August 30, 2011
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Bainian Feng, Whitney W. Smith, John C. Chabala
  • Publication number: 20110190237
    Abstract: The present invention includes macrocyclic prodrug compounds, pharmaceutical compositions containing them. The present invention also includes use of these compounds in the treatment of various diseases including an autoimmune disease, an inflammatory disease, a neurological or neurodegenerative disease, cancer, a cardiovascular disease, allergy, asthma, a hormone-related disease, and tumors or symptoms resulting from neurofibromatosis.
    Type: Application
    Filed: August 23, 2010
    Publication date: August 4, 2011
    Applicants: NEXGENIX PHARMACEUTICALS, UNIVERSITE DE STRASBOURG
    Inventors: James Heck, Nicolas Winssinger, John C. Chabala, Sofia Barluenga, Ruihong Chen, Allan Rubenstein, Jin-Chen Yu
  • Publication number: 20100210670
    Abstract: Quinazolinones of formulae (a, b, c and d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Application
    Filed: February 11, 2010
    Publication date: August 19, 2010
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Bainian Feng, Whitney W. Smith, John C. Chabala
  • Patent number: 7763628
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: July 27, 2010
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustav E Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Publication number: 20100063073
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Application
    Filed: August 25, 2009
    Publication date: March 11, 2010
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Patent number: 7589098
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: March 21, 2005
    Date of Patent: September 15, 2009
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Publication number: 20080182864
    Abstract: Quinazolinones of formulae (a, b, c and d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Application
    Filed: June 28, 2007
    Publication date: July 31, 2008
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Bainian Feng, Whitney W. Smith, John C. Chabala
  • Patent number: 7294634
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed.
    Type: Grant
    Filed: July 20, 2004
    Date of Patent: November 13, 2007
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Patent number: 7230000
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: June 12, 2007
    Assignee: Cytokinetics, Incorporated
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Patent number: 7119089
    Abstract: Phenothiazine derivatives of formula (I) are disclosed. The compounds are inhibitors of the mitotic kinesin KSP and are useful in the treatment of cellular proliferative diseases, such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: October 10, 2006
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, John C. Chabala
  • Patent number: 7105668
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: September 12, 2006
    Assignee: Cytokinetics, Inc.
    Inventors: Gustave Bergnes, Whitney W. Smith, John C. Chabala
  • Patent number: 6992082
    Abstract: Phenothiazine derivatives of formula (I) are disclosed. The compounds are inhibitors of the mitotic kinesin KSP and are useful in the treatment of cellular proliferative diseases, such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: January 31, 2006
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, John C. Chabala
  • Publication number: 20040254203
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Application
    Filed: July 20, 2004
    Publication date: December 16, 2004
    Applicant: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Patent number: 6831085
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: December 14, 2004
    Assignee: Cytokinetics, Inc.
    Inventors: Gustave Bergnes, Whitney W. Smith, John C. Chabala
  • Publication number: 20040132719
    Abstract: Phenothiazine derivatives of formula (I) are disclosed. The compounds are inhibitors of the mitotic kinesin KSP and are useful in the treatment of cellular proliferative diseases, such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation.
    Type: Application
    Filed: February 17, 2004
    Publication date: July 8, 2004
    Inventors: Jeffrey T Finer, John C Chabala
  • Publication number: 20040132830
    Abstract: Triphenylmethane derivatives of the formula (I) are disclosed.
    Type: Application
    Filed: February 17, 2004
    Publication date: July 8, 2004
    Inventors: Jeffrey T Finer, John C Chabala, Evan Lewis