Patents by Inventor John C. Chabala

John C. Chabala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective hydrogenation products of C-076 compounds and derivatives thereof
    Patent number: 4199569
    Abstract: Derivatives of C-076 are described in which the C-076 molecule, as series of macrolides, has a specific unsaturation, at the 22,23-position, catalytically reduced. Further reaction of the reduced C-076 compounds are also possible. The compounds thus produced have profound anthelmintic, insecticidal, ectoparasiticidal and acaracidal activity. Compositions containing the described C-076 derivatives as the active ingredient thereof are also disclosed.
    Type: Grant
    Filed: July 31, 1978
    Date of Patent: April 22, 1980
    Assignee: Merck & Co., Inc.
    Inventors: John C. Chabala, Michael H. Fisher
  • 13-Halo and 13-deoxy derivatives of C-076 compounds
    Patent number: 4173571
    Abstract: Derivatives of the C-076 compounds are disclosed wherein the 13-position is unsubstituted. The compounds are prepared by removing the glycosyl groups on the 13-position of the C-076 compounds isolated from the fermentation broth of Streptomyces avermitilis, followed by halogenation and subsequent removal of the halogen. The disclosed compounds are antiparasitic, anthelmintic, insecticidal and acaricidal agents.
    Type: Grant
    Filed: December 19, 1977
    Date of Patent: November 6, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John C. Chabala, Michael H. Fisher, Helmut H. Mrozik
  • 13-Halo and 13-deoxy C-076 compounds
    Patent number: 4171314
    Abstract: Derivatives of the C-076 compounds are disclosed wherein the 13-position is unsubstituted or substituted by a halogen atom. The compounds are prepared by removing the glycosyl groups on the 13-position of the C-076 compounds isolated from the fermentation broth of Streptomyces avermitilis. This is followed by substitution of the 13-hydroxy group with a halogen, and subsequent removal of the halogen. The disclosed compounds are antiparasitic, anthelmintic, insecticidal and acaracidal agents.
    Type: Grant
    Filed: December 19, 1977
    Date of Patent: October 16, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John C. Chabala, Michael H. Fisher, Helmut H. Mrozik