Patents by Inventor John C. Sih

John C. Sih has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 19,20-Didehydro-13,14-dihydro-PG.sub.2 compounds
    Patent number: 4269995
    Abstract: The present invention provides novel 19,20-didehydro-13,14-dihydro-PG.sub.2 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 17, 1979
    Date of Patent: May 26, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-cis-4,5-didehydro-PG.sub.1 analogs
    Patent number: 4269996
    Abstract: The present invention provides novel 19-hydroxy-cis-4,5-didehydro-PG.sub.1 analogs methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 26, 1979
    Date of Patent: May 26, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-19-methyl-6-oxo-PGF.sub.1 amides
    Patent number: 4269779
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-6-oxo-PGF.sub.1 amides which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: May 26, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-6a-carba-PGI.sub.2 amides
    Patent number: 4267371
    Abstract: The present invention provides novel 19-hydroxy-6a-carba-PGI.sub.1 amides which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-19-methyl-6-oxo-PGF.sub.1 sulfonylamides
    Patent number: 4267352
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-6-oxo-PGF.sub.1 sulfonylamides which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-19-methyl-trans-2,3-didehydro-PG.sub.1 compounds
    Patent number: 4267367
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-trans-2,3-didehydro-PG.sub.1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-19-methyl-inter-oxa-PG.sub.1 compounds
    Patent number: 4267370
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-inter-oxa-PG.sub.1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-19-methyl-cis-4,5-didehydro-13,14-dihydro-PG.sub.1 compounds
    Patent number: 4267368
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-cis-4,5-didehydro-13,14-dihydro-PG.sub.1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 2-Decarboxy-2-hydroxymethyl-19-hydroxy-19-methyl-6A-carba-PGI.sub.2 compounds
    Patent number: 4267395
    Abstract: The present invention provides novel 2-decarboxy-2-hydroxymethyl-19-hydroxy-19-methyl-6a-carba-PGI.sub.1 compounds which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-19-methyl-trans-2,3-didehydro-13,14-dihydro-PG.sub.1 compounds
    Patent number: 4267369
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-trans-2,3-didehydro-13,14-dihydro-PG.sub.1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-19-methyl-6,9.alpha.-epoxymethano-PGF compounds
    Patent number: 4267114
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-6,9.alpha.-epoxy-methano-PGF compounds which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Dihydro-inter-phenylene-11-deoxy-11-hydroxymethyl-19-oxo-PGE.sub.1 compounds
    Patent number: 4267357
    Abstract: The present invention provides novel 13,14-dihydro-inter-3,7-inter-m-phenylene-4,5,6-trinor-3-oxa-11-deoxy-11-h ydroxymethyl-19-oxo-PGE.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 11-Deoxy-inter-phenylene-19-oxo-PGF.sub.1 compounds
    Patent number: 4266072
    Abstract: The present invention provides novel 11-deoxy-inter-phenylene-19-oxo-PGF.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: May 5, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-7,8-didehydro-PGI.sub.1 compounds
    Patent number: 4265820
    Abstract: The present invention provides novel 19-hydroxy-7,8-didehydro-PGI.sub.1 compounds which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: May 5, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-PG amides
    Patent number: 4264522
    Abstract: The present invention provides novel 19-hydroxy-PG amides methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 26, 1979
    Date of Patent: April 28, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19,20-Didehydro-13,14-dihydro-PG.sub.1 amides
    Patent number: 4264523
    Abstract: The present invention provides novel 19,20-didehydro-13,14-dihydro-PG.sub.1 amides, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 17, 1979
    Date of Patent: April 28, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19,20-Didehydro-PG.sub.1 amides
    Patent number: 4264524
    Abstract: The present invention provides novel 19,20-didehydro-PG.sub.1 amides methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 17, 1979
    Date of Patent: April 28, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-4-oxo-PGI.sub.1 compounds
    Patent number: 4263210
    Abstract: The present invention provides novel 19-hydroxy-4-oxo-PGI.sub.1 compounds which are useful for pharmacological purposes. e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: April 21, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-inter-phenylene-11-deoxy -11-hydroxymethyl-19-oxo-PGE.sub.1 compounds
    Patent number: 4262132
    Abstract: The present invention provides novel 13,14-didehydro-interphenylene-11-deoxy-11-hydroxymethyl-19-oxo-PGE.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: April 14, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14,-Di hydro-inter-phenylene-11-deoxy-11-hydroxymethyl-9-deoxy-9-methylene-19-ox o-PGF.sub.1 compounds
    Patent number: 4262136
    Abstract: The present invention provides novel 13,14-dihydro-inter-3,7-inter-m-phenylene4,5,6-trinor-3-oxa-11-deoxy-11-hy droxymethy-9-deoxy-9-methylene-19-oxo-PGF.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: April 14, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih