Abstract: A lateral flow chromatography test device is disclosed that includes a stopping mechanism which enables a user of the test device to stop reactions of a test by pushing the stopping mechanism downward to remove materials flowing along a test strip in the test device at a time instructed by the manufacturer or decided by the user. This stopping mechanism is adapted to freeze the test result at the stopping time so as to keep the test result as a permanent record. The invention enables qualitative tests to become quantitative or semi-quantitative tests.

Abstract: A method for detecting high antigen concentration is disclosed. The method enables the mobile-phase antibody, in the presence of excessive amount of antigen, to form the antibody-antigen-antibody sandwich with the immobilized solid-phase antibody effectively in a rapid lateral flow chromatographic immunoassay. The mobile-phase and/or immobilized solid-phase antibody are treated with soluble coatings to generate a delaying mechanism, so that antigen-antibody binding occurs only when both phases of antibodies and antigen are in very close proximity. A user friendly immunoassay device with a sample over-flow mechanism also facilitates such antigen-antibody binding.

Abstract: A lateral flow chromatography test device is disclosed that includes a stopping mechanism which enables a user of the test device to stop reactions of a test by pushing the stopping mechanism downward to remove materials flowing along a test strip in the test device at a time instructed by the manufacturer or decided by the user. This stopping mechanism is adapted to freeze the test result at the stopping time so as to keep the test result as a permanent record. The invention enables qualitative tests to become quantitative or semi-quantitative tests.

Abstract: A data storage system includes an active data store (ADS) and a passive data store (PDS) that, when implemented as a network-attached database appliance, facilitates the separation of operating system software components and data.

Abstract: Systems and methods for managing data within a networked computer environment including application servers and a plurality of storage devices utilize a collection of service modules, each separately addressable from and in communication with the application servers and the storage devices and providing system-wide services to the application servers and the storage devices.

Abstract: A display for a data-appliance cabinet comprises a panel having front and rear surfaces and dimensions matching a front-side portion of a data-appliance cabinet allocated to an absent accessory device, a translucent window through the panel, a light source for illuminating the translucent window via the rear surface of the panel, and means facilitating installation of the backlit display.

Abstract: This application discloses provides a process for the introduction of nitro-group functionality into a compound which contains also a site of unsaturation and/or oxygen functionality by direct (one step) oxidation of an oxime functional group mediated by a molybdenum VI/VII peroxo complex, the process comprising: (a) providing a substrate of Formula I containing an oxime functional group; ?wherein R1 and R2 are selected independently from linear, branched or cyclic alkyl and linear, branched or cyclic alkenyl groups, optionally substituted, with the proviso that at least one of R1 or R2 contains a carbon/carbon double bond; and (b) contacting said substrate of Formula I with a molybdenum oxidation complex, thereby oxidizing said oxime functional group to a nitro functional group to yield the structure of Formula III. Where R1 and R2 are as defined above.

Abstract: A thermoelectric unit for a thermoelectric insulated container. The thermoelectric unit is configured to be inserted in a small opening in the insulated container. A cold side heat sink is mounted on the portion of the thermoelectric unit that extends inside of the insulated container, and a hot side heat sink is mounted on a portion of the thermoelectric unit that extends outside. The thermoelectric unit is arranged so that a thermoelectric module for the thermoelectric unit, the cold side heat sink, and the hot side heat sink are aligned linearly. A hot side fan and motor unit is mounted on the outside of the hot side heat sink and a cold side fan and motor unit is mounted on the outside of the cold side heat sink. The hot and cold side fan and motor units may also be mounted linearly with the hot and cold side heat sinks.

Abstract: A crystalline polymorph of a bislulfate salt of a thrombin receptor antagonist compound, which exhibits a powder x-ray diffraction profile substantially the same as that shown in FIG. 1, or which exhibits a differential scanning calorimtery profile substantially the same as that shown in FIG. 3, and is represented by the formula for Compound 2: and processes for preparing Compound 2 are disclosed. Pharmaceutical compositions comprising the polymorph of the bisulfate salt and at least one excipient or carrier, and methods of using the polymorph of Compound 2 to treat a variety of physiological disorders, such as thrombosis, are also disclosed.

Abstract: Thermoelectric unibody cooler apparatus with a unibody insulated vessel, a unibody insulated lid, and a thermoelectric heat pump assembly. A preferred embodiment includes the unibody insulated vessel manufactured as a single piece of semi-rigid insulating material being both insulation and structural support. A preferred embodiment includes the thermoelectric heat pump assembly assembled as one integral cassette and where the integral cassette forms a dissengageable friction and thermal bond with a compatible mounting area of the unibody insulated vessel.

Abstract: Universal Thermoelectric Module Apparatus with a thermoelectric heat pump assembly, an air circulation system, a structural plate, and an insulated interface.

Abstract: Stowable Cooler with insulated walls, resealable mechanical devices, a stowing medium, and an access lid. A preferred embodiment includes the insulated walls having a soft or semi-rigid construction. The lower edges of the insulated walls are permanently secured to the stowing medium forming a flexible bond. The side edges of the insulated walls each feature at least one half of at least one resealable mechanical device. The lower edges of each resealable mechanical device are secured to the stowing medium. The stowable cooler has a stowing mode and a usage mode. The stowing mode is true when the sealable mechanical devices are unsealed, and the usage mode is true when the sealable mechanical devices are sealed. The stowing medium is of sufficient volume to house the insulated walls while in stowing mode in a plurality of overlapping flats.

Abstract: The present invention relates to an improved process for preparing himbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield on the desired enantiomer.

Abstract: A process is provided for preparing azetidinones useful as intermediates in the synthesis of penems and as hypocholesterolemic agents, comprising reacting a ?-(substituted-amino)amide, a ?-(substituted-amino)acid ester, or a ?-(substituted-amino)thiolcarbonic acid ester with a silylating agent and a cyclizing agent selected from the group consisting of alkali metal carboxylates, quaternary ammonium carboxylates, quaternary ammonium hydroxides, quaternary ammonium alkoxides, quaternary ammonium aryloxides and hydrates thereof, or the reaction product of: (i) at least one quaternary ammonium halide and at least one alkali metal carboxylate; or (ii) at least one quaternary ammonium chloride, quaternary ammonium bromide, or quaternary ammonium iodide and at least one alkali metal fluoride, wherein a quaternary ammonium moiety of the cyclizing agent is unsubstituted or substituted by one to four groups independently selected from the group consisting of alkyl, arylalkyl and arylalkyl-alkyl.

Abstract: An apparatus for Cooled Or Heated On Demand Drinking Water having a thermal accumulator with embedded serpentine fluid conduit, a network of independently controlled thermoelectric heat transfer modules, and a network of temperature control modules. A preferred embodiment includes the thermal accumulator as a single die-cast thermally conductive metallic medium free of seams and an embedded pipe free of coupling structure.

Abstract: A thermoelectric unit for a thermoelectric insulated container. The thermoelectric unit is configured to be inserted in a small opening in the insulated container. A cold side heat sink is mounted on the portion of the thermoelectric unit that extends inside of the insulated container, and a hot side heat sink is mounted on a portion of the thermoelectric unit that extends outside. The thermoelectric unit is arranged so that a thermoelectric module for the thermoelectric unit, the cold side heat sink, and the hot side heat sink are aligned linearly. A hot side fan and motor unit is mounted on the outside of the hot side heat sink and a cold side fan and motor unit is mounted on the outside of the cold side heat sink. The hot and cold side fan and motor units may also be mounted linearly with the hot and cold side heat sinks.

Abstract: Disclosed is an apparatus and method for controlling boiling condition of hot H3PO4 solution by adjusting the vapor extracting rate thereof, wherein an acid tank filled with hot H3PO4 solution to a level surface is located in a treatment room and a temperature thermocouple is arranged above the level surface of the hot H3PO4 solution to monitor the vapor temperature near the level surface of the H3PO4 solution. The vapor temperature is used to adjust the extracting rate of the treatment room by control of a damper connected to an outlet of the treatment room. According to the present invention, the treatment apparatus and method can control the boiling condition of the hot H3PO4 solution thereof by properly adjusting the extracting rate, and therefore avoid defects and loss of control in manufacturing processes.

Abstract: An invasive therapeutic probe assembly and related methods for application of RF energy to a volume of body tissue are provided. The probe assembly includes an RF source configured to provide an RF energy having selected characteristics, a probe having a probe shaft and an antenna positioned therein, and a feed line for providing conductivity from the RF source to the antenna probe. The probe assembly is adapted to generate a zone of therapeutic effectiveness having a selected geometry and volume. The related method includes positioning the probe in a selected location with reference to a target tissue, initiating an electromagnetic field from the antenna having a selected geometry, and producing a zone of therapeutic effectiveness having a selected geometry and volume. The producing step preferably includes, taking periodic temperature measurements from sensors positioned at a selected location, and manipulating the selected characteristics of the RF energy to include duration and/or power level.

Abstract: An invasive therapeutic probe assembly and related methods for application of RF energy to a volume of body tissue are provided. The probe assembly includes an RF source configured to provide an RF energy having selected characteristics, a probe having a probe shaft and an antenna positioned therein, and a feed line for providing conductivity from the RF source to the antenna probe. The probe assembly is adapted to generate a zone of therapeutic effectiveness having a selected geometry and volume. The related method includes positioning the probe in a selected location with reference to a target tissue, initiating an electromagnetic field from the antenna having a selected geometry, and producing a zone of therapeutic effectiveness having a selected geometry and volume. The producing step preferably includes, taking periodic temperature measurements from sensors positioned at a selected location, and manipulating the selected characteristics of the RF energy to include duration and/or power level.