Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: The invention provides improved devices, methods, and systems for shrinking of collagenated tissues, particularly for treating urinary incontinence in a noninvasive manner by directing energy to a patient's own support tissues. This energy heats fascia and other collagenated support tissues, causing them to contract. The energy can be applied intermittently, often between a pair of large plate electrodes having cooled flat electrode surfaces, the electrodes optionally being supported by a clamp structure. Such cooled plate electrodes are capable of directing electrical energy through an intermediate tissue and into fascia while the cooled electrode surface prevents injury to the intermediate tissue, particularly where the electrode surfaces are cooled before, during, and after an intermittent-heating cycle. Ideally, the plate electrode comprises an electrode array including discrete electrode surface segments so that the current flux can be varied to selectively target the fascia.

Abstract: A pigment product suitable for use in a coating composition to provide a gloss coating on paper, the pigment product comprising a processed particulate kaolin whose particles have a particle size distribution such that at least 80% by weight of the particles have an equivalent spherical diameter less than 2 &mgr;m and not less than 8%, preferably not less than 12%, by weight of the particles have an equivalent spherical diameter less than 0.25 &mgr;m and whose particles have a shape factor of at least 45, preferably at least 50.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: Levetiracetam, an N-type calcium channel antagonist drug, has been discovered to be highly effective in treating migraine headaches. When administered orally on a daily basis, it reduces the adverse traits (including frequency, severity, and duration) of migraines among chronic sufferers. When injected intravenously, it was highly effective in entirely curing or greatly reducing full-blown acute migraine headaches, even among patients who could not be treated adequately by triptans or any other known drugs.

Abstract: A pigment product suitable for use in a coating composition to provide a gloss coating on paper, the pigment product comprising a processed particulate kaolin whose particles have a particle size distribution such that at least 80% by weight of the particles have an equivalent spherical diameter less than 2 &mgr;m and not less than 8%, preferably not less than 12%, by weight of the particles have an equivalent spherical diameter less than 0.25 &mgr;m and whose particles have a shape factor of at least 45, preferably at least 50.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: A pigment product suitable for use in a coating composition to provide a gloss coating on paper, the pigment product comprising a processed particulate kaolin whose particles have a particle size distribution such that at least 80% by weight of the particles have an equivalent spherical diameter less than 2 &mgr;m and not less than 8%, preferably not less than 12%, by weight of the particles have an equivalent spherical diameter less than 0.25 &mgr;m and whose particles have a shape factor of at least 45, preferably at least 50.

Abstract: A pigment product suitable for use in a coating composition to provide a gloss coating on paper, the pigment product comprising a processed particulate kaolin produced from a naturally platy kaolin clay having a particle size distribution such that about 50% to 60% by weight of the particles have an esd less than 2 &mgr;m and less than 25% by weight of the particles have an esd less than 0.25 &mgr;m and a shape factor of at least 15. In processing, the crude kaolin is ground to a shape factor greater than 50 to produce even greater “platy” clay. The pigment product has a particle size distribution such that at least 80% by weight of the particles have an esd less than 2 &mgr;m and greater than 12% and less than 35% by weight of the particles have an esd less than 0.25 &mgr;m and whose surface area is greater than 12 m2/g when measured by the BET method.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: A pigment product suitable for use in a coating composition to provide a gloss coating on paper, the pigment product comprising a processed particulate kaolin produced from a naturally platy kaolin clay having a particle size distribution such that about 50% to 60% by weight of the particles have an esd less than 2 &mgr;m and less than 25% by weight of the particles have an esd less than 0.25 &mgr;m and a shape factor of at least 15. In processing, the crude kaolin is ground to a shape factor greater than 50 to produce even greater “platy” clay. The pigment product has a particle size distribution such that at least 80% by weight of the particles have an esd less than 2 &mgr;m and greater than 12% and less than 35% by weight of the particles have an esd less than 0.25 &mgr;m and whose surface area is greater than 12 m2/g when measured by the BET method.

Abstract: A pigment product suitable for use in a coating composition to provide a gloss coating on paper, the pigment product comprising a processed particulate kaolin produced from a naturally platy kaolin clay having a particle size distribution such that about 50% to 60% by weight of the particles have an esd less than 2 &mgr;m and less than 25% by weight of the particles have an esd less than 0.25 &mgr;m and a shape factor of at least 15. This platy clay can be blended with b-fraction clay component. In processing, the crude kaolin is ground to a shape factor greater than 50 to produce even greater “platy” clay. The pigment product has a particle size distribution such that at least 80% by weight of the particles have an esd less than 2 &mgr;m and greater than 12% and less than 35% by weight of the particles have an esd less than 0.25 &mgr;m and whose surface area is greater than 12 m2/g when measured by the BET method.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.

Abstract: Improved cathode cans, for use in electrochemical cells. Broadly, the cans comprise corrosion-susceptible core layers, and protective metal layers such as nickel overlying the core layer and disposed between the core layer and a, preferably electroless plated, duplex coating layer such as nickel, which overlies severed edges of the core layer, and also typically overlies the protective metal layers. Thickness of the duplex coating layer is less, preferably no more than 75%, of the thickness of the protective metal layer. Combined thickness of the protective metal layer and duplex coating layer is preferably about 75 microinches (0.002 mm) to 200 microinches (0.005 mm). Thickness of the duplex coating layer alone is preferably about 25 microinches (0.0006 mm) to 100 microinches (0.0025 mm). Combined thickness of the protective metal layer and the duplex coating layer is preferably at least 1.25 times, up to no more than 2 times, thickness of the protective metal layer.

Abstract: The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred shapes of such particles are microspheres, particularly those having diameters of about 1 to about 1,000 microns. The stable shaped particles of the present invention are particularly well-suited to the fabrication of pharmaceutical formulations, particularly where sustained release and uniform bioavailability are desired. The storage stable particles are formed by a solid state crystallization of allotropic organic compounds. The solid state crystallization process of the present invention affords a means for achieving a storage stable crystalline form of said allotropic compound without loss or deterioration of the original particle dimensions.