Patents by Inventor John F. Engelhardt

John F. Engelhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pseudotyped adeno-associated viruses and uses thereof
    Publication number: 20030103939
    Abstract: Pseudotyped rAAV and methods of using pseudotyped rAAV are provided.
    Type: Application
    Filed: July 12, 2002
    Publication date: June 5, 2003
    Inventors: John F. Engelhardt, Ziying Yan
  • Adeno-associated virus vectors
    Publication number: 20020197237
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Application
    Filed: January 22, 2002
    Publication date: December 26, 2002
    Applicant: University of Iowa Research Foundation
    Inventors: John F. Engelhardt, Dongsheng Duan
  • Adeno-associated virus vectors
    Patent number: 6436392
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: August 20, 2002
    Assignee: University of Iowa Research Foundation
    Inventors: John F. Engelhardt, Dongsheng Duan
  • Non-human animal model of a human airway, methods of use
    Patent number: 5667766
    Abstract: A non-human animal characterized by a human airway, the human airway being open-ended. The human airway is characterized by cells derived from the human respiratory system. The non-human animal and the human airway it carries are useful as models of human airways, particularly diseased human airways, for example, human CF airways. They are also useful to predict the efficacy or toxicity of agents and therapies on human airways, particularly on diseased human airways, for example, human CF airways.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 16, 1997
    Assignee: The Regents Of The University Of Michigan
    Inventors: James M. Wilson, John F. Engelhardt
  • Non-human animal model of a human airway
    Patent number: 5625128
    Abstract: A non-human animal characterized by a human airway, the human airway being open-ended. The human airway is characterized by cells derived from the human respiratory system. The non-human animal and the human airway it carries are useful as models of human airways, particularly diseased human airways, for example, human CF airways. They are also useful to predict the efficacy or toxicity of agents and therapies on human airways, particularly on diseased human airways, for example, human CF airways.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: April 29, 1997
    Assignee: The Regents of the University of Michigan
    Inventors: James M. Wilson, John F. Engelhardt