Patent number: 6326500
Abstract: Compounds of formula (I)
and salts thereof, wherein
R1 is hydrogen, halo, cyano, cyanoalkyl, alkyl, alkoxy, phenoxy, phenyl, alkoxycarbonyl, —NR13R14, —N(R15)SO2R16, haloalkoxy, haloalkyl, arylalkoxy, hydroxy, phenylalkyl, alkoxycarbonylvinyl, —SOnR7, alkoxycarbonylalkyl, carboxylalkyl, —CONR11R12, carbamoylvinyl, —O—SO2R21, 4,5-dihydrothiazol-2-yl, 4,4-dimethyl-2-oxazolin-2-yl, —NR60R61 or —(O)z—L3—G (G=−NR22R23, —SOmR26, CONR27R28 or —OR29);
R2 and R3 are independently hydrogen halo, alkyl, alkoxy, —NR13R14, haloalkoxy, haloalkyl, hydroxy, —SOnR7 or —NR60R61;
L1 is a bond, alkylene, cycloalkylene or cycloalkylidene;
T is a bond, O, S, SO, SO2, CO or 1,3-dioxolan-2-ylidene;
L2 is alkylene, cycloalkylene or cycloalkylidene;
R6 is hydrogen or alkyl;
Q is alkylene; and
Y is imidazolyl,
which are antiinflammatory, antiallergic and immunodulant agents.
Type:
Grant
Filed:
December 27, 2000
Date of Patent:
December 4, 2001
Assignee:
Abbott Laboratories
Inventors:
David John Calderwood, Adrian John Fisher, James Edward Jeffery, Colin Gerhart Pryce Jones, Paul Rafferty