Abstract: The invention relates to compounds of the Formula: salts thereof, pharmaceutical compositions thereof, combinations thereof, as well as therapeutic methods of treatment and prevention.

Abstract: An improved core for mounting on one or more core engaging elements such as a pair of chucks and a method of making an improved core are provided. The core is adapted to wind and unwind material thereon. The core comprises a high coefficient of friction coating disposed on the inner surface of the core to improve core-chuck interaction.

Abstract: An occipital plate and hinged rod assembly. The occipital plate having a screw-attachment section having through holes for securing the occipital plate to a skull, a laterally-extending section, a tulip connector, a slide clip disposed underneath the laterally-extending section and engaging a base of the tulip connector, and an insert ring encompassing side walls of tulip connector. The laterally-extending section, the tulip connector, the slide clip, and the insert ring have respective surfaces with complementary curvatures that fit together. The hinged rod assembly is connected to the occipital plate by rods.

Abstract: A system includes an energy storage device geographically proximate a plurality of load centers. The energy storage device is coupled to one or more of the plurality of load centers for supplying energy to the load centers and is also coupled to an energy generation source for receiving energy from the energy generation source. The system also includes a control system that is operable to receive energy market data, monitor the plurality of load centers, the energy storage device, and the energy generation source, and control the charging and dispatching of the energy storage device based on the monitoring and the energy market data.

Abstract: A turbine nozzle for a turbine includes: an airfoil having a shape having a nominal profile substantially in accordance with at least a portion of Cartesian coordinate values of X, Y and Z set forth in TABLE I. The Cartesian coordinate values are non-dimensional values of from 0% to 100% convertible to distances by multiplying the values by a height of the airfoil expressed in units of distance. The X and Y values are connected by smooth continuing arcs to define airfoil profile sections at each distance Z along at least a portion of the airfoil, and the profile sections at the Z distances are joined smoothly with one another to form the nominal profile. A trailing edge profile for a turbine nozzle is also disclosed.

Abstract: Identifying network applications using images generated from payload data and time data. In some embodiments, a method may include capturing target payload data and target time data from a target flow of network packets between a target client application and a target server application, generating a target image from the target payload data and the target time data, and determining, based on the target image, an output including an extent to which the target image matches one of a plurality of predetermined images in order to determine a likelihood that the target client application and/or the target server application matches one of a plurality of predetermined client applications and/or one of a plurality of predetermined server applications.

Abstract: Techniques for implementing and/or operating a pipe deployment system that includes pipe deployment equipment, which facilitates deploying a pipe segment from a pipe coil, and a pipe drum, which includes a drum body around which the pipe coil is to be disposed. The pipe drum is to be disposed on the pipe deployment equipment and the drum body includes a drum core as well as a lower paddle assembly and an upper paddle assembly, which are slidably secured to the drum core. The pipe deployment system maintains the paddle assemblies in a retracted state to enable the drum body to be inserted into the pipe coil, extends the lower paddle assembly to a more extended state to facilitate raising the drum core, and retracts the lower paddle assembly to a less extended state and extends the upper paddle assembly to the less extended state to facilitate lifting the pipe coil.

Abstract: Connections between nodes and tubes are provided. An apparatus can include additively manufactured first and second nodes, a tube, and an interconnect connecting the tube to the first and second nodes. An apparatus can include a node having an end portion with inner and outer concentric portions forming an annular gap therebetween, and a tube having an end portion extending into the gap.

Abstract: A surgical implant and a surgical kit. The surgical implant has a body portion comprising a first hole formed in an exterior surface of the body portion, a second hole adjacent the first hole, and at least one through-hole within the body portion and extending entirely thought a depth of the body portion extending entirely thought a depth of the body portion. The implant has a central opening abutting the body portion and extending through the body portion. The first hole has a first sidewall and a first cavity in the body portion, the second hole has a second sidewall and a second cavity in the body portion, and the first cavity and the second cavity have an interconnected opening there between. The surgical kit includes the surgical implant and an intervertebral insertion device.

Abstract: Identifying network applications using images generated from payload data and time data. In some embodiments, a method may include training a convolutional neural network with training images generated from training payload data and training time data from flows of network packets, capturing target payload data and target time data from a target flow of network packets between a target client application and a target server application, generating a target image from the target payload data and the target time data, providing the target image as input to the trained convolutional neural network, and employing the trained convolutional neural network to determine an output including an extent to which the target image matches one of the training images in order to determine a likelihood that the target client application and/or the target server application matches one of the training client applications and/or one of the training server applications.

Abstract: A turbine nozzle for a turbine includes: an airfoil having a shape having a nominal profile substantially in accordance with at least a portion of Cartesian coordinate values of X, Y and Z set forth in TABLE I. The Cartesian coordinate values are non-dimensional values of from 0% to 100% convertible to distances by multiplying the values by a height of the airfoil expressed in units of distance. The X and Y values are connected by smooth continuing arcs to define airfoil profile sections at each distance Z along at least a portion of the airfoil, and the profile sections at the Z distances are joined smoothly with one another to form the nominal profile. A trailing edge profile for a turbine nozzle is also disclosed.

Abstract: A surgical implant and a surgical kit. The surgical implant has a body portion comprising a first hole formed in an exterior surface of the body portion, a second hole adjacent the first hole, and at least one through-hole within the body portion and extending entirely thought a depth of the body portion extending entirely thought a depth of the body portion. The implant has a central opening abutting the body portion and extending through the body portion. The first hole has a first sidewall and a first cavity in the body portion, the second hole has a second sidewall and a second cavity in the body portion, and the first cavity and the second cavity have an interconnected opening there between.

Abstract: A firearm rear stabilizing crutch is disclosed having a shaft with a proximal end and a distal end, and an underarm firearm support on the proximal end of the shaft. The underarm firearm support has a support base with front and rear ends and a top element extending therebetween, with the top element defining a generally curved profile extending from proximate the front end to proximate the rear end. A support nose extends from the front end of the support base, with the support nose defining a recess therein for accommodating a firearm buttstock. The distal end of the shaft is configured to be engaged with the ground when the crutch is being used to support a firearm in a shooting position. Some embodiments of the crutch include integrated storage for the shaft and spikes.

Abstract: A surgical implant and a surgical kit. The surgical implant has a body portion comprising a first hole formed in an exterior surface of the body portion, a second hole adjacent the first hole, and at least one through-hole within the body portion and extending entirely thought a depth of the body portion extending entirely thought a depth of the body portion. The implant has a central opening abutting the body portion and extending through the body portion. The first hole has a first sidewall and a first cavity in the body portion, the second hole has a second sidewall and a second cavity in the body portion, and the first cavity and the second cavity have an interconnected opening there between.

Abstract: The present application provides a turbine rotor blade including an airfoil shape. The airfoil shape may have a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in Table I. The Cartesian coordinate values of X, Y and Z are non-dimensional values from 0% to 100% convertible to dimensional distances expressed in a unit of distance (e.g., inches) by multiplying the Cartesian coordinate values of X, Y and Z by a height of the airfoil in the unit of distance. The X and Y values, when connected by smooth continuing arcs, define airfoil profile sections at each Z value. The airfoil profile sections at Z values may be joined smoothly with one another to form a complete airfoil shape.

Abstract: Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.

Abstract: A firearm heater system for warming a scope of a firearm. The firearm heater system comprising an upper portion, a lower portion, a pocket portion and an edge portion. The upper portion is attached to the pocket portion. The lower portion is attached to the pocket portion. The edge portion is attached to the pocket portion. The edge portion comprise one or more dial apertures. The one or more dial apertures configured to allow access to portions of the scope. The pocket portion comprise a pocket. The pocket is configured to receive a portion of a hand warmer. The firearm heater system configured to wrap around a portion of the scope and hold a portion of the hand warmer against the scope.

Abstract: Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.

Abstract: Systems and methods are disclosed for online distribution of content based on a user sentiment index. The method may include receiving, over a network and from a user device, one or more user generated inputs and calculating the user sentiment index based on the one or more user generated inputs. The method may also include receiving, over the network, from a content or advertising provider, instructions on publishing content or advertising to a webpage based on the calculated user sentiment index, and publishing content for display on user devices over the network based on a comparison of the calculated user sentiment index and the received instructions.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.