Abstract: The invention includes sample preparation cartridges and apparatuses. The invention provides means for lysing and optionally selectively capturing at least one compound in a sample to purify, concentrate, and/or select for the at least one compound. The invention can be used in conjunction with a sample processing instrument to create a fully-automated or near-fully-automated sample workflow.

Abstract: Embodiments of the present disclosure relate to techniques for inducing physiological perturbations in a subject via neuromodulation, e.g., peripheral neuromodulation of a region of interest of an organ. The nature and degree of the perturbations may be related to the subject's clinical condition. Accordingly, an assessment of one or more characteristics of the perturbations may be used to determine a clinical condition of the subject.

Abstract: A heating device may include a substrate and a heating element disposed on a surface of the substrate. The heating element may include an ohmically resistive coating having a layer thickness of 2 to 300 microns. The ohmically resistive coating may include at least 30% by weight of at least one ductile or malleable metal and a plurality of electrically resistive particles. The ohmically resistive coating may be deposited via the at least one of the cold spray and the solid state deposition performed at a temperature below at least one of a melting temperature and a partially softening temperature of the at least one ductile or malleable metal. The ohmically resistive coating may exhibit less heterogeneity and porosity than a thermally sprayed coating, may have a density of 90% or greater, and may have a porosity of 10% or less.

Abstract: Methods, systems, and apparatuses, including computer programs encoded on computer storage media, for configuring a set of language model neural networks, e.g., a first large language model and a second smaller-sized language model, and performing a machine learning task on new inputs using the set of language model neural networks. Configuring the language model neural networks and performing a machine learning task can include leveraging the ability of a first large language model to follow prompt-engineered instructions and perform chain-of-thought reasoning, while also fine-tuning a second, smaller language model neural network to optimize the machine learning task performance.

Abstract: Various laser level designs including the ability to physically/mechanically mask light emitted from the laser level are shown. In one example, the laser level includes physical barriers that can be moved between open and closed positions to selectively block or mask a desired portion of the projected laser plane.

Abstract: An apparatus and methods for installation of an offshore platform for supporting equipment installations is provided. The apparatus includes a platform configured to support offshore equipment supported by a structure such as a modular column assembly. The modular column assembly can be comprised of main barrel joint bundles.

Abstract: The invention includes sample preparation cartridges and apparatuses. The invention provides means for lysing and optionally selectively capturing at least one compound in a sample to purify, concentrate, and/or select for the at least one compound. The invention can be used in conjunction with a sample processing instrument to create a fully-automated or near-fully-automated sample workflow.

Abstract: Various embodiments include apparatuses and methods to form the apparatus. In one embodiment, the apparatus is a flow meter having inlet and outlet portions for transporting a fluid along a flow path. A flow-restrictor element is formed within the flow path to impart a pressure drop to the fluid. A flow sensor has a first surface of the flow sensor in direct fluid communication with fluid flowing upstream of the flow-restrictor element and a second surface, on a portion of the flow sensor opposite to the first surface, in direct fluid communication with fluid flowing downstream of the flow-restrictor element. The flow sensor senses a differential pressure in the fluid due to the at least one flow-restrictor element. Other apparatuses and systems are disclosed.

Abstract: Input context for a statistical dialog manager may be provided. Upon receiving a spoken query from a user, the query may be categorized according to at least one context clue. The spoken query may then be converted to text according to a statistical dialog manager associated with the category of the query and a response to the spoken query may be provided to the user.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.

Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; a proximal balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the proximal balloon; a push tube slidably mounted to the sleeve; and a distal balloon secured to the distal end of the push tube, the interior of the distal balloon being in fluid communication with the push tube, wherein the distal balloon is capable of assuming a deflated condition and an inflated condition, and further wherein when the distal balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and when the distal balloon is in its inflated condition, the axial opening is closed down.

Abstract: An adjustable tubular insulator, such as for insulating a pipe, has a body having a width, a thickness, a length, and a longitudinal slit extending the length of the body. The width and the thickness define a first inner diameter. The body is sized and configured for engaged receipt of a first pipe size having first outer diameter. The body has first and second longitudinal seams at first and second predetermined distances from the longitudinal slit. The first and second longitudinal seams demark first and second detachable insulator strips having different predetermined widths. One or both of the detachable insulator strips may be selectively removed or repositioned to reduce the width of the body such that the body is sized and configured for engaged receipt of a second pipe size, the second pipe size having an outer diameter less than the first outer diameter.

Abstract: Methods and systems for manufacturing a transdermal sampling and analysis device for non-invasively and transdermally obtaining biological samples from a subject and determining levels of analytes of the obtained biological samples are provided. A method of manufacturing the device may improve performance and includes forming channel structures on the lid of the device, thereby making the spacer/channel support structures physically independent and separable from the sensing electrode. Other methods of manufacturing the device may improve performance and include forming at least one of the electrodes on each of the base and the lid, and forming a recessed second spacer layer over the channel support structures, thereby separating the channel support structures and the electrode on the lid to allow a larger area of the electrode to be exposed to the biological sample.

Abstract: An exemplary method comprises receiving information associated with a game-playing transaction conducted between a user device and a game-playing terminal, wherein the game-playing transaction is associated with a request for playing a game; determining a location of the user device associated with the game; determining the user device is located in an approved location associated with the game; and processing the game-playing transaction based on determining the user device is located in the approved location associated with the game. The game-playing transaction is conducted on a first communication interface, and the information associated with the game-playing transaction is received on a first or second communication interface.

Abstract: A battery electrode composition includes a population of jagged composite particles, in which each of the jagged composite particles includes silicon and carbon. In some embodiments, 90% or more of the jagged composite particles in the population are characterized by aspect ratios of 2.3 or less and 50% or more of the jagged composite particles in the population are characterized by aspect ratios of 1.25 or more. In some embodiments, the population is characterized by a particle size distribution (PSD) as determined by laser particle size distribution analysis (LPSA) and a fiftieth-percentile volume-weighted particle size parameter D50 of the PSD is in a range of about 2.0 to about 17.0 ?m.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into the tissue to cause a change in a glucose transporter pathway molecule and/or an incretin pathway molecule. In one embodiment, the neuromodulation is performed as a treatment of a metabolic disorder.

Abstract: Systems and methods are described for outputting light and/or audio using one or more light and/or audio sources of a robot. The light sources may be located on one or more legs of the robot, a bottom portion of the robot, and/or a top portion of the robot. The audio sources may include a speaker and/or an audio resonator. A system can obtain sensor data associated with an environment of the robot. Based on the sensor data, the system can identify an alert. For example, the system can identify an entity based on the sensor data and identify an alert for the entity. The system can instruct an output of light and/or audio indicative of the alert using the one or more light and/or audio sources. The system can adjust parameters of the output based on the sensor data.

Abstract: cMET inhibitors can be used in the treatment of glioblastoma, including disseminated glioblastoma harboring MET amplification.

Abstract: A battery anode includes a binder, a conductive additive, and an active material blend including silicon (Si)-comprising active material particles and graphite active material particles. In some embodiments, the battery anode has a reversible capacity loading in a range of about 2 mAh/cm2 to about 16 mAh/cm2, the silicon (Si)-comprising active material particles exhibit a specific capacity in a range of about 800 mAh/g to about 3000 mAh/g, and the silicon (Si)-comprising active material particles contribute from about 25% to about 99% of a total capacity of the battery anode.