Abstract: A system, e.g., a system on a chip (SoC) includes a first domain including a first processor configured to boot the system; a second domain including a processing subsystem having a second processor; and isolation circuitry between the first domain and the second domain During boot-up of the system, the first processor provides code to the second domain. When the code is executed by the second processor, it configures the processing subsystem as either a safety domain or as a general-purpose processing domain. The safety domain may an external safety domain or an internal safety domain.

Abstract: The invention includes sample preparation cartridges and apparatuses. The invention provides means for lysing and optionally selectively capturing at least one compound in a sample to purify, concentrate, and/or select for the at least one compound. The invention can be used in conjunction with a sample processing instrument to create a fully-automated or near-fully-automated sample workflow.

Abstract: Systems and methods for training models to improve fairness.

Abstract: Embodiments of the present disclosure are directed to coated glass articles which reduce glass particle formation caused by glass to glass contact in pharmaceutical glass filling lines.

Abstract: An exemplary method comprises receiving information associated with a game-playing transaction conducted between a user device and a game-playing terminal, wherein the game-playing transaction is associated with a request for playing a game; determining a location of the user device associated with the game; determining the user device is located in an approved location associated with the game; and processing the game-playing transaction based on determining the user device is located in the approved location associated with the game. The game-playing transaction is conducted on a first communication interface, and the information associated with the game-playing transaction is received on a first or second communication interface.

Abstract: Apparatus for transdermal delivery of a powdered agent to a patient, the apparatus comprising a fluid source comprising a fluid; a nozzle extending distally from the fluid source, the nozzle comprising a proximal end, a distal end and a lumen extending from the proximal end to the distal end; a blister containing a powdered agent disposed within the lumen of the nozzle; and an actuation element for releasing the fluid from the fluid source, wherein the actuation element causes the released fluid to be propelled through the blister with sufficient pressure to entrain the powdered agent into the released fluid and move the entrained powdered agent through the lumen of the nozzle and out the distal end of the nozzle.

Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a RRM2 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a RRM2 gene using said pharmaceutical composition; and methods for inhibiting the expression of RRM2 in a cell.

Abstract: An example modular meal system includes two or more modular meal components. Example modular meal components include a tray, a meal component disposed within the tray, and a sauce component disposed within the tray. The meal component is selected from a protein component, a starch component, a vegetable component, an appetizer component, and a dessert component. Each modular meal component is configured and/or formulated to reach at least 165° F. or at least 167° F. when heated from frozen for a heating time period within the range of from about 20 minutes to about 60 minutes and at a heating temperature within the range of about 350° F. to about 450° F.

Abstract: An example modular meal system includes two or more modular meal components. Example modular meal components include a tray, a meal component disposed within the tray, and a sauce component disposed within the tray. The meal component is selected from a protein component, a starch component, a vegetable component, an appetizer component, and a dessert component. Each modular meal component is configured and/or formulated to reach at least 165° F. or at least 167° F. when heated from frozen for a heating time period within the range of from about 20 minutes to about 60 minutes and at a heating temperature within the range of about 350° F. to about 450° F.

Abstract: A computer-implemented method is disclosed. The method includes: receiving, from a web server associated with a protected resource, a first signal including a request to validate a bearer token submitted by a client device to the web server, the bearer token including a digital signature; validating the bearer token, the validating including verifying the digital signature using a public key associated with an end user of the client device; and in response to validating the bearer token, sending to the web server a second signal including a notification that the bearer token is valid.

Abstract: A projection system and method therefor comprises a first light source configured to emit a first-eye light, wherein the first-eye light includes a first set of wavelengths; a second light source configured to emit a second-eye light, wherein the second-eye light includes a second set of wavelengths; a first projector including first projection optics configured to receive a first input light; and an optical switch configured to be switched between an a first mode and a second mode, wherein the optical switch is configured to, in the first mode, combine the first-eye light and the second-eye light into a combined light and direct the combined light to the first projection optics as the first input light.

Abstract: The subject matter of the present disclosure generally relates to techniques for following a treatment protocol having one or more treatment parameters to cause a targeted physiological outcome at a distal site, assessing an expression level of a gene in a region of interest after completing the treatment protocol, and modifying the one or more treatment parameters based on the expression level of the gene. The treatment protocol may include one or more ultrasound energy treatments to the region of interest.

Abstract: An example peripheral device includes circuitry to identify a target device that matches the device type identifier of the peripheral device. The example circuitry of the peripheral device is to cause selection of an input component device, transmission of a request to place the input component of the target device into an instruction set receiver mode, and operation of an output component of the peripheral device to produce audio output or video output that represents the instruction set in response to a determination that an instruction set version identifier of the target device mismatches the instruction set version identifier of the peripheral device.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue at multiple regions of interest, concurrently or consecutively. The neuromodulation may result in tissue displacement, which may be observed through changes in one or more molecules of interest.

Abstract: The present invention relates to an improved ball tossing device that is portable and adjustable to accommodate a variety of different balls and lobbing preferences. This may be achieved through various features including some or all of the following: a ball feeding mechanism using a rotating disk with an offset feed channel to deliver balls to the ball tossing queue; a catapult arm that uses a motor/spring mechanism to toss balls in the queue out of the machine; an indexer feature for isolating the ball to be tossed from the other balls in the queue; and adjustable features that allow users to vary ball trajectory of the ball being tossed.

Abstract: A computer-implemented method is disclosed. The method includes: receiving, via a communication interface from a client application executing on a first device, a first signal including a request to obtain an access token for accessing a protected resource, the request including a public key associated with an end user; validating the request to obtain the access token; and in response to validating the request: encrypting an authorization code associated with the request using the public key to generate a first code; and transmitting, via the communication interface to the client application on the first device, a second signal including both the access token for accessing the protected resource and the first code.

Abstract: The disclosure is directed, in part, to improved systems and nucleic acids for modifying target DNA.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue at multiple regions of interest, concurrently or consecutively. The neuromodulation may result in tissue displacement, which may be observed through changes in one or more molecules of interest.

Abstract: Disclosed is a woven product adapted to be used as a primary backing layer for a surface, ground or floor covering comprising artificial or synthetic grass or turf. The woven product comprises at least a first woven layer and a second woven layer, wherein the first and second woven layers are interwoven, the first woven layer comprises a plurality of warp tapes/threads and a plurality of weft tapes/threads, the warp tapes/threads and the weft tapes/threads of the first woven layer being substantially perpendicular to one another. The second woven layer comprises a plurality of warp tapes/threads and a plurality of weft tapes/threads, the warp tapes/threads and the weft tapes/threads of the second woven layer being substantially perpendicular to one another.

Abstract: The present invention provides novel methods of using nitric oxide donor compounds for treating infectious diseases, for example, COVID-19.