Abstract: A differentially pumped mass spectrometer system comprises a mass spectrometer having first and second pressure chambers through which, during use, ions are conveyed along a path. A pump assembly for differentially evacuating the chambers is attached to the mass spectrometer. The pump assembly comprises a housing attached to the mass spectrometer and a cartridge inserted into the housing. The cartridge has a plurality of inlets each for receiving fluid from a respective pressure chamber and a pumping mechanism for differentially pumping fluid from the chambers. The cartridge is inserted into the housing such that the pumping mechanism is inclined relative to the ion path, but with the cartridge protruding into the mass spectrometer to such an extent that at least one of the inlets at least partially protrudes into its respective chamber without crossing the ion path.

Abstract: A weighting agent composition for use in a cement slurry for downhole operations in a subterranean well, the composition comprising a finely divided solid weighting agent; and a dispersant comprising a sulphonic acid, salt or derivative thereof, the sulphonic acid having the general formula I: -[A(OSOO?M+)-B-A?(OSOO?M+)]n-??(I) wherein A and A? are each an aromatic moiety; B is an aliphatic moiety; OSOO?M+ is a solubilising group consisting of sulphonic acid, a salt or derivative thereof; and n is an integer of at least 2. The composition is of particular use in formulating a cement slurry for use in a downhole cementing operation. There is also provided a method of preparing a finely divided weighting agent using the sulphonic acid of formula I, a cement formulation comprising the composition and a method of cementing a subterranean well.

Abstract: A target map area system for an online game is described. A player selects a target map area of an online neighbor of an online social game. Reward information from the target map area resulting from a successful attack from the player in the target map area of the online neighbor is generated to the player prior to the attack. A result of the attack in the target map area of the online neighbor based on a profile of the player and a profile of the online neighbor is determined. An outcome on the target map area is generated based on the result of the attack.

Abstract: A vacuum pump comprises a first pumping section (106), and, downstream therefrom, a second pumping section (108), The pump comprises a first pump inlet (120) through which fluid can enter the pump and pass through both the first and second pumping sections towards a pump outlet, and a second pump inlet (122) through which fluid can enter the pump and pass through only the second pumping section towards the outlet. The second pumping section (108) comprises an externally threaded rotor (109).

Abstract: A collaborative diplomacy mechanics system for an online game is described. A player selects an ally to be engaged in a combat mode of an online social game against an enemy. The profile of the selected ally is retrieved. An ally power up weapon is generated based on the profile of the selected ally. The ally power up weapon is applied against a combat unit of an enemy of a player in the combat mode. The ally power up weapon can also be applied on a combat unit of the player in the combat mode.

Abstract: A target map area system for an online game is described. A player selects a target map area of an online neighbor of an online social game. Reward information from the target map area resulting from a successful attack from the player in the target map area of the online neighbor is generated to the player prior to the attack. A result of the attack in the target map area of the online neighbor based on a profile of the player and a profile of the online neighbor is determined. An outcome on the target map area is generated based on the result of the attack.

Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.

Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.

Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, (CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process includes reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.

Abstract: A method for the production of functional proteins including hormones by renal cells in a three dimensional culturing process responsive to shear stress uses a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-?-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating an in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.

Abstract: A differentially pumped mass spectrometer system comprises a mass spectrometer having first and second pressure chambers through which, during use, ions are conveyed along a path. A pump assembly for differentially evacuating the chambers is attached to the mass spectrometer. The pump assembly comprises a housing attached to the mass spectrometer and a cartridge inserted into the housing. The cartridge has a plurality of inlets each for receiving fluid from a respective pressure chamber and a pumping mechanism for differentially pumping fluid from the chambers. The cartridge is inserted into the housing such that the pumping mechanism is inclined relative to the ion path, but with the cartridge protruding into the mass spectrometer to such an extent that at least one of the inlets at least partially protrudes into its respective chamber without crossing the ion path.

Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.

Abstract: A differentially pumped mass spectrometer system comprises a mass spectrometer having first and second pressure chambers through which, during use, ions are conveyed along a path. A pump assembly (10) for differentially evacuating the chambers (62, 66, 68) is attached to the mass spectrometer. The pump assembly comprises a housing (12) attached to the mass spectrometer and a cartridge (14) inserted into the housing. The cartridge has a plurality of inlets (16, 18, 20) each for receiving fluid from a respective pressure chamber (62, 68, 66) and a pumping mechanism (30, 32, 34) for differentially pumping fluid from the chambers. The cartridge is inserted into the housing such that the pumping mechanism (10) is inclined relative to the ion path (76), but with the cartridge protruding into the mass spectrometer to such an extent that at least one of the inlets (16, 18) at least partially protrudes into its respective chamber (62, 68) without crossing the ion path.

Abstract: A method for the production of functional proteins including hormones by renal cells in a three dimensional culturing process responsive to shear stress uses a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-?-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating an in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.

Abstract: An antenna for microwave tumor ablation provides coaxial antenna conductors surrounded by an insulated sleeve of length and size promoting destructive interference of axial microwave energy passing inside and outside of the sleeve to limit the tail of SAR power toward the skin.

Abstract: The present invention provides isolated, purified ?9 THC. In another embodiment, the invention provides pharmaceutical compositions comprising isolated, purified ?9 THC and a pharmaceutically acceptable carrier. In another embodiment, the invention provides methods of preparing pharmaceutical compositions comprising isolated, purified ?9 THC and a pharmaceutically acceptable carrier.

Abstract: A scroll compressor having a scroll wall arrangement with a fixed scroll having fixed scroll walls and an orbiting scroll having orbiting scroll wall, an inlet at a radially outer portion and an outlet at a radially central portion, a first flow path defined by the orbiting and fixed scroll walls and extending from the inlet to the outlet, gas entering through inlet at a pressure and exhausting through outlet at a second pressure higher than the first pressure. Scroll wall arrangement having a second inlet through which gas enters at a third pressure and follows a second fluid path where it is exhausted through the outlet at the second pressure to form two flow paths having respective inlets. The third pressure at which gas enters through inlet is different from the first pressure, and lower than the second pressure.

Abstract: ?9 THC acid is obtained from plant material and extracted into an aqueous solvent under conditions of pH control. The acid is converted to a salt and the salt extracted into a polar solvent, yielding acid of high purity. The ?9 THC acid is then converted to ?9 THC which is further purified and combined with a carrier for pharmaceutical use.

Abstract: A differentially pumped mass spectrometer system comprises a mass spectrometer having first and second pressure chambers through which, during use, ions are conveyed along a path. A pump assembly (10) for differentially evacuating the chambers (62, 66, 68) is attached to the mass spectrometer. The pump assembly comprises a housing (12) attached to the mass spectrometer and a cartridge (14) inserted into the housing. The cartridge has a plurality of inlets (16, 18, 20) each for receiving fluid from a respective pressure chamber (62, 68, 66) and a pumping mechanism (30, 32, 34) for differentially pumping fluid from the chambers. The cartridge is inserted into the housing such that the pumping mechanism (10) is inclined relative to the ion path (76), but with the cartridge protruding into the mass spectrometer to such an extent that at least one of the inlets (16, 18) at least partially protrudes into its respective chamber (62, 68) without crossing the ion path.

Abstract: The present invention provides a method for production of functional proteins including hormones by renal cells in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-a-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.