Abstract: The present invention provides for a method of culturing cells and inducing the expression of at least one gene in the cell culture. The method provides for contacting the cell with a transcription factor decoy oligonucleotide sequence directed against a nucleotide sequence encoding a shear stress response element.

Abstract: A scroll compressor which comprises a scroll assembly comprising two scroll walls, and a drive for causing a relative orbiting motion between the scroll walls for compressing fluid on two fluid flow paths between an inlet and an exhaust of the scroll assembly. A first fluid flow path is formed between a wall surfaces of the scroll walls and a second fluid flow path is formed between another facing wall surfaces of the scroll walls. A first ambient clearance A1 is selected between the first two facing surfaces, and a second ambient clearance A2 is selected between the second two facing surfaces, and where the first and the second ambient clearances are selected independently from each other. Independent selection permits each ambient clearance to be designed according to its own performance requirements, to take into account thermal expansion and manufacturing tolerances.

Abstract: A system and method of displaying information by an electronic price label which uses thresholds to minimize the number of messages to an electronic price label. The system includes a record for an item associated with the electronic price label which contains the thresholds. The thresholds divide the information into a number of ranges including a first range of information and a second range of information.

Abstract: A system and method of displaying information by an electronic price label which uses thresholds to minimize the number of messages to an electronic price label. The system includes a record for an item associated with the electronic price label which contains the thresholds. The thresholds divide the information into a number of ranges including a first range of information and a second range of information.

Abstract: A scroll compressor which comprises a scroll assembly comprising two scroll walls, and a drive for causing a relative orbiting motion between the scroll walls for compressing fluid on two fluid flow paths between an inlet and an exhaust of the scroll assembly. A first fluid flow path is formed between a wall surfaces of the scroll walls and a second fluid flow path is formed between another facing wall surfaces of the scroll walls. A first ambient clearance A1 is selected between the first two facing surfaces, and a second ambient clearance A2 is selected between the second two facing surfaces, and where the first and the second ambient clearances are selected independently from each other. Independent selection permits each ambient clearance to be designed according to its own performance requirements, to take into account thermal expansion and manufacturing tolerances.

Abstract: The present invention provides a method for production of functional proteins including hormones by renal cells in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel. Natural mixture of renal cells expresses the enzyme 1-a-hydroxylase which can be used to generate the active form of vitamin D: 1,25-diOH vitamin D3. The fibroblast cultures and co-culture of renal cortical cells express the gene for erythropoietin and secrete erythropoietin into the culture supernatant. Other shear stress response genes are also modulated by shear stress, such as toxin receptors megalin and cubulin (gp280). Also provided is a method of treating in-need individual with the functional proteins produced in a three dimensional co-culture process responsive to shear stress using a rotating wall vessel.

Abstract: A vacuum pump comprising a shaft rotatable by means of a motor, at least two spaced pump stages mounted on the shaft, a first pump inlet through which gas can pass for passage through all the pump stages for evacuating a first system and a second pump inlet through which gas can enter the pump at an inter-stage location for passage through only subsequent stages of the pump for evacuating a second system, said first and second systems each having a gas outlet flange for attachment to a first or a second pump inlet, in which the vacuum pump is mounted relative to the respective first and second systems such that the longitudinal axis of the shaft is inclined to each of the gas outlet flanges.

Abstract: A granular material for the sorption of organic material comprises granules of an inorganic silicon-containing material having negatively charged sites and having an average granule size of at least 50 microns, the granules being porous and coated on their outer and inner surfaces with a film of an organic polymeric material having polar and non-polar moieties. The organic polymeric material may form from 0.25% to 10% by weight of the weight of the inorganic material.The granular material may be prepared by treating an aqueous suspension of the inorganic material with a material comprising the organic polymeric material. The inorganic silicon-containing material may comprise a silicate, eg. an aluminosilicate, eg. a kandite and/or smectite clay which may be a foamed material which has been calcined. The polymeric material may comprise a nitrogen-containing polymer which can be employed in the form of an acid colloidal medium, eg. a melamine-aldehyde polymer.

Abstract: A ceramic particulate material which comprises particles having an irregular three dimensional surface profile having jagged projections and a median particle diameter of 200 micrometers or less, the particles being fractals produced by comminution of foamed ceramic material. The material may be such that in a sphere of rotation of the particle, from 30% to 80% of the volume of the sphere is void, the remainder being continuous solid material. The material may be produced by a process which includes providing a suspension of ceramic forming particles e.g., of an aluminosilicate such as clay, in a liquid medium; incorporating a gas in the liquid medium before or after formation of the suspension therein to produce a foamed suspension; extruding the foamed suspension; optionally drying the extrudate formed thereby; calcining the extrudate; and comminuting the calcined material, e.g. by crushing. The material may be used as a substitute for diatomite.

Abstract: The adaptive sequential pattern memory search technique only examines the contents of a subset of the total number of memory locations in each search for information representative of a character string. The subset includes a plurality of storage locations and each examination is performed in one concurrent read operation. If the character string is not matched, the memory must be updated to store information representative of the unmatched string. This updating process selects one location from the subset for storing this representative information. Advantageously, an indicator of when each stored representative information last matched a character string is maintained and utilized in the selection process. In addition, to avoid operational errors associated with outputting invalid information from the "child" of a previously discarded "parent", an indication of the time each stored entry is created is utilized to remove such invalid information as it is detected in the updating process.

Abstract: The invention relates to a method of and apparatus for agitating and pumping particulate solids which are settled in and beneath a liquid by rotating a vaned impeller which is attached to a pump such that pressure waves are set up in the liquid and the settled solids, the solids being loosened so as to be pumpable, and the agitator being arranged to impart to its surroundings an axial component of movement towards the pump inlet.