Abstract: A hand-held conduit bending tool includes an elongated handle and a bender head disposed on the handle. The bender head comprising a body portion having at least one curved channel therein. In an embodiment, the channel is elliptical in cross-section. A handle mount is at a rear end of the body portion and rearward of the hook portion and a foot pedal is formed. In some embodiments, two channels are provided to accommodate two differently sized conduits. Markings are provided to enable use of the tool in a head-down position and in a head-up position.

Abstract: A hand-held conduit bending tool includes an elongated handle and a bender head disposed on the handle. The bender head comprising a body portion having at least one curved channel therein. In an embodiment, the channel is elliptical in cross-section. A handle mount is at a rear end of the body portion and rearward of the hook portion and a foot pedal is formed. In some embodiments, two channels are provided to accommodate two differently sized conduits. Markings are provided to enable use of the tool in a head-down position and in a head-up position.

Abstract: Disclosed here are uses of autophagy inhibitors for treating a subject at risk of suffering from an aneurysm. The present disclosure demonstrates that autophagy plays a role in THSD1-mediated focal adhesion stability and aneurysm formation and characterizes molecular targets for therapeutic intervention.

Abstract: A fish tape case is configured to house a fish tape. The fish tape includes a shell having an upper base wall, a lower base wall, an inner side wall extending between inner perimeters of the base walls and forming a central aperture through the shell, an outer side wall extending between outer perimeters of the base walls and defining an outer diameter of the shell, the walls defining a cavity therein, the upper base wall having a first opening therethrough in communication with the cavity through which the fish tape can exit, and the outer side wall having a second opening therethrough in communication with the cavity through which the fish tape can exit. A storage reel is mounted in the cavity for holding the fish tape.

Abstract: Disclosed here are uses of autophagy inhibitors for treating a subject at risk of suffering from an aneurysm. The present disclosure demonstrates that autophagy plays a role in THSD1-mediated focal adhesion stability and aneurysm formation and characterizes molecular targets for therapeutic intervention.

Abstract: The disclosure describes global transcriptome profiling in human vascular endothelial cells upon THSD1 knockdown and identification from these studies of specific genes and pathways that are THSD1. The analysis highlights a role for THSD1 in regulating endothelial to mesenchymal transition and other pathways. The analysis also demonstrates that endothelial cell injury is the first event of an intracranial aneurysm. The disclosure provides novel cell lines and reagents used for better understanding the molecular mechanism of THSD1 biology.

Abstract: Disclosed here are uses of anti-podosome therapies for treating a subject at risk of suffering from an aneurysm. The present disclosure demonstrates that endothelial podosomes plays a role in THSD1-mediated focal adhesion stability and aneurysm formation and characterizes molecular targets for therapeutic intervention.

Abstract: Disclosed here are metal coils conjugated to TGF-beta ligand(s) or TGF-beta activator(s) to improve the outcome of existing surgical treatments on intracranial aneurysm patients and methods for using the same.

Abstract: A fish tape case is configured to house a fish tape in accordance with some example embodiments is provided. The fish tape includes a shell having a rotatable tray therein. A fish tape extends through openings in the shell and the tray. The fish tape case does not include a handle.

Abstract: A hand-held conduit bending tool includes an elongated handle and a bender head disposed on the handle. The bender head comprising a body portion having at least one curved channel therein. In an embodiment, the channel is elliptical in cross-section. A handle mount is at a rear end of the body portion and rearward of the hook portion and a foot pedal is formed. In some embodiments, two channels are provided to accommodate two differently sized conduits. Markings are provided to enable use of the tool in a head-down position and in a head-up position.

Abstract: A fish tape case is configured to house a fish tape. The fish tape includes a shell having an upper base wall, a lower base wall, an inner side wall extending between inner perimeters of the base walls and forming a central aperture through the shell, an outer side wall extending between outer perimeters of the base walls and defining an outer diameter of the shell, the walls defining a cavity therein, the upper base wall having a first opening therethrough in communication with the cavity through which the fish tape can exit, and the outer side wall having a second opening therethrough in communication with the cavity through which the fish tape can exit. A storage reel is mounted in the cavity for holding the fish tape.

Abstract: A fish tape case is configured to house a fish tape in accordance with some example embodiments is provided. The fish tape includes a shell having a rotatable tray therein. A fish tape extends through openings in the shell and the tray. The fish tape case does not include a handle.

Abstract: An ergonomic fish tape configured to house a fish tape in accordance with some example embodiments is provided. The fish tape includes a shell having an upper base wall, a lower base wall, an inner side wall extending between inner perimeters of the base walls and forming a central aperture through the shell, an outer side wall extending between outer perimeters of the base walls and defining an outer diameter of the shell, the walls defining a cavity therein, and a storage tray within the cavity. An opening through which the fish tape can pass is provided through the outer side wall. The fish tape case does not include a handle, and the walls of the shell are devoid of surfaces which would indicate or suggest to a user as to how to grip the fish tape case.

Abstract: An ergonomic fish tape configured to house a fish tape in accordance with some example embodiments is provided. The fish tape includes a shell having an upper base wall, a lower base wall, an inner side wall extending between inner perimeters of the base walls and forming a central aperture through the shell, an outer side wall extending between outer perimeters of the base walls and defining an outer diameter of the shell, the walls defining a cavity therein, and a storage tray within the cavity. An opening through which the fish tape can pass is provided through the outer side wall. The fish tape case does not include a handle, and the walls of the shell are devoid of surfaces which would indicate or suggest to a user as to how to grip the fish tape case.

Abstract: A method of cleaning plastic chips includes introducing a mixture of plastic chips and water to an in-feed of a housing. The mixture of plastic chips and water is impelled from the in-feed within the housing and agitated so that debris on the plastic chips is abraded by adjacent chips and agitators until substantially all debris has been removed from the plastic chips. Water and debris are discharged through a screen to a debris discharge. Cleaned plastic chips are discharged to a plastic chip discharge that is further from the in-feed than the debris discharge. Chip discharge takes place when the pressure of the plastic chips at the plastic chip discharge exceeds a threshold.

Abstract: A handle assembly includes a mounting bracket and a handle. The mounting bracket supports the handle which can pivot relative to the mounting bracket. The mounting bracket includes first and second mounting elements which prevent the handle from rotating more than approximately ninety degrees relative to the mounting bracket.

Abstract: A tool is provided into which a saw blade can be mounted and removed therefrom. The tool includes a housing have a groove therein. An attachment assembly is mounted in the groove and can be slid within the groove. The attachment assembly includes a first part, a second part, and a member attaching the parts together, while allowing the parts to move relative to each other. The saw blade is inserted between the first and second parts and is removable therefrom. A spring retainer is affixed within the housing. The attachment assembly is moveable within the housing to abut against the spring retainer. When the attachment assembly abuts the spring retainer, the second parts can be moved out of engagement with each other to allow the removal of the saw blade from therebetween.

Abstract: A handle assembly includes a mounting bracket and a handle. The mounting bracket supports the handle which can pivot relative to the mounting bracket. The mounting bracket includes first and second mounting elements which prevent the handle from rotating more than approximately ninety degrees relative to the mounting bracket.